ROCK inhibitor Y-27632 suppresses dissociation-induced apoptosis of murine prostate stem/progenitor cells and increases their cloning efficiency

PLoS ONE

Volumn 6, Issue 3, 2011, Pages

  Zhang, Li ^a   Valdez, Joseph M ^a   Zhang, Boyu ^a   Wei, Lei ^b   Chang, Jiang ^c   Xin, Li ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; AMIDE; BIOLOGICAL MARKER; PROTEIN KINASE INHIBITOR; PYRIDINE DERIVATIVE; RHO KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL ACTIVITY; CELL CLONING; CELL RENEWAL; COLONY FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REPRESSION; EXTRACELLULAR MATRIX; IN VITRO STUDY; MOUSE; NONHUMAN; PROSTATE EPITHELIUM; PROTEIN FUNCTION; STEM CELL; ANIMAL; BIOASSAY; CELL CLONE; CLONOGENIC ASSAY; CYTOLOGY; DOWN REGULATION; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; EPITHELIUM CELL; MALE; METABOLISM; MULTICELLULAR SPHEROID; PROSTATE;

MURINAE;

AMIDES; ANIMALS; APOPTOSIS; BIOLOGICAL ASSAY; BIOLOGICAL MARKERS; CLONE CELLS; COLONY-FORMING UNITS ASSAY; DOWN-REGULATION; EPITHELIAL CELLS; MALE; MICE; PROSTATE; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; PYRIDINES; RHO-ASSOCIATED KINASES; SPHEROIDS, CELLULAR; STEM CELLS;

EID: 79953153425     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0018271     Document Type: Article

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