High affinity soluble ILT2 receptor: A potent inhibitor of CD8+ T cell activation

Protein and Cell

Volumn 1, Issue 12, 2010, Pages 1118-1127

  Moysey, Ruth K ^a,b   Li, Yi ^a   Paston, Samantha J ^a   Baston, Emma E ^a   Sami, Malkit S ^a   Cameron, Brian J ^a   Gavarret, Jessie ^a   Todorov, Penio ^a   Vuidepot, Annelise ^a   Dunn, Steven M ^a,c   Pumphrey, Nicholas J ^a,d   Adams, Katherine J ^a   Yuan, Fang ^a   Dennis, Rebecca E ^a   Sutton, Deborah H ^a   Johnson, Andy D ^a   Brewer, Joanna E ^a,d   Ashfield, Rebecca ^a   Lissin, Nikolai M ^a   Jakobsen, Bent K ^a  

^a Immunocore Limited   (United Kingdom)

^b Oxford Nanopore Technologies Ltd   (United Kingdom)

^c MERCK SERONO S A   (Switzerland)

^d Adaptimmune Ltd   (United Kingdom)

Author keywords

autoimmunity; binding affinity; cell surface molecules; cellular activation; phage display

Indexed keywords

GAMMA INTERFERON; HLA ANTIGEN; IMMUNOGLOBULIN LIKE TRANSCRIPT 2 RECEPTOR; IMMUNOGLOBULIN LIKE TRANSCRIPT 2 RECEPTOR C132 FC FUSION PROTEIN; IMMUNOGLOBULIN LIKE TRANSCRIPT 2 RECEPTOR C138 FC FUSION PROTEIN; IMMUNOGLOBULIN LIKE TRANSCRIPT 2 RECEPTOR C50; IMMUNOGLOBULIN LIKE TRANSCRIPT 2 RECEPTOR C57; IMMUNOGLOBULIN LIKE TRANSCRIPT 2 RECEPTOR C64; IMMUNOGLOBULIN LIKE TRANSCRIPT 2 RECEPTOR C64 FC FUSION PROTEIN; IMMUNOGLOBULIN RECEPTOR; INTERLEUKIN 2; MACROGOL DERIVATIVE; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; AUTOIMMUNITY; CD8+ T LYMPHOCYTE; CELL KILLING; CELL STRAIN K 562; CONTROLLED STUDY; CROSS LINKING; CYTOKINE RELEASE; DRUG DESIGN; DRUG POTENCY; DRUG SCREENING; GENE FUSION; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; LIGAND BINDING; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PHAGE DISPLAY; PRIORITY JOURNAL; RECEPTOR AFFINITY; T LYMPHOCYTE ACTIVATION;

EID: 79953145408     PISSN: 1674800X     EISSN: 16748018     Source Type: Journal    
DOI: 10.1007/s13238-010-0144-5     Document Type: Article

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