Clr4/Suv39 and RNA quality control factors cooperate to trigger RNAi and suppress antisense RNA

Science

Volumn 331, Issue 6024, 2011, Pages 1624-1627

  Zhang, Ke ^a   Fischer, Tamas ^a,c   Porter, Rebecca L ^a,d   Dhakshnamoorthy, Jothy ^a   Zofall, Martin ^a   Zhou, Ming ^b   Veenstra, Timothy ^b   Grewal, Shiv I S ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLR4 SUV39 METHYLTRANSFERASE; COMPLEMENTARY RNA; FUNGAL PROTEIN; METHYLTRANSFERASE; MLO3 PROTEIN; RECOMBINANT PROTEIN; RNA; SMALL INTERFERING RNA; TRAMP PROTEIN; UNCLASSIFIED DRUG;

CHROMOSOME; DEGRADATION; ENZYME ACTIVITY; GENE EXPRESSION; MOLECULAR ANALYSIS; QUALITY CONTROL; RNA; YEAST;

ARTICLE; CENTROMERE; CONTROLLED STUDY; GENE LOCUS; GENE SILENCING; HETEROCHROMATIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; QUALITY CONTROL; RNA DEGRADATION; RNA INTERFERENCE; RNA PROCESSING; RNA TRANSCRIPTION; SACCHAROMYCES CEREVISIAE;

CELL CYCLE PROTEINS; CENTROMERE; EUCHROMATIN; HISTONES; METHYLATION; METHYLTRANSFERASES; MUTATION; RNA INTERFERENCE; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, ANTISENSE; RNA, FUNGAL; RNA-BINDING PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; SCHIZOSACCHAROMYCES; SCHIZOSACCHAROMYCES POMBE PROTEINS;

EUKARYOTA; SCHIZOSACCHAROMYCETACEAE;

EID: 79953133682     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1198712     Document Type: Article

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30. We thank R. Dhar and R. Allshire for antibody to Mlo3 and strains, E. Chen for helpful contributions, and F. Reyes-Turcu, N. Komissarova, and M. Lichten for comments on manuscripts and discussions. Microarray data are available at the National Center for Biotechnology Information's Gene Expression Omnibus repository under accession numbers GSE26999 and GSE17271. This work is supported by the Intramural Research Program of the National Institutes of Health, National Cancer Institute.