Evaluation of the in vivo radiosensitizing activity of etanidazole using tumor-bearing chick embryo

Journal of Radiation Research

Volumn 52, Issue 2, 2011, Pages 208-214

  Abe, Chiaki ^a   Uto, Yoshihiro ^a   Nakae, Takashi ^a   Shinmoto, Yuuya ^a   Sano, Keiichiro ^a   Nakata, Hiroko ^a   Teraoka, Mizue ^a   Endo, Yoshio ^b   Maezawa, Hiroshi ^a   Masunaga, Shin Ichiro ^c   Nakata, Eiji ^a   Hori, Hitoshi ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

IRRADIATION; RADIATION;

CHICK EMBRYO; COMBINATION TREATMENTS; EXPERIMENTAL ANIMALS; GROWTH SUPPRESSIONS; HYPOXIC CELLS; IN-VIVO; RADIOSENSITIZERS; RESEARCH FIELDS; TUMOR GROWTH; X RAY IRRADIATION;

TUMORS;

ANIMALIA;

EID: 79953127255     PISSN: 04493060     EISSN: 13499157     Source Type: Journal    
DOI: 10.1269/jrr.10122     Document Type: Article

References (28)

1. Hanahan D and Weinberg RA (2000) The Hallmarks of Cancer. Cell 100: 57-70.
2. Trédan O, et al (2007) Drug resistance and the solid tumor microenvironment. J Natl Cancer Inst 99: 1441-1454.
3. Brown JM and Wilson WR (2004) Exploiting tumor hypoxia in cancer treatment. Nat Rev Cancer 4: 437-447.
4. Das B, et al (2008) Hypoxia enhances tumor stemness by increasing the invasive and tumorigenic side population fraction. Stem Cells 26: 1818-1830.
5. Diehn M, et al (2009) Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature 458: 780-783.
6. Sugie C, et al (2005) Reevaluation of the radiosensitizing effects of sanazole and nimorazole in vitro and in vivo. J Radiat Res 46: 453-459.
7. Nakae T, et al (2008) Design, synthesis, and radiosensitizing activities of sugar-hybrid hypoxic cell radiosensitizers. Bioorg Med Chem 16: 675-682.
8. Oya N, et al (1995) Optical isomers of a New 2-nitroimidazole nucleoside analog (PR-350 series): radiosensitization efficacy and toxicity. Int J Radiation Oncology Biol Phys 33: 119-127.
9. Overgaard J, et al (2005) Plasma osteopontin, hypoxia, and response to the hypoxia sensitiser nimorazole in radiotherapy of head and neck cancer: results from the DAHANCA 5 randomised double-blind placebo-controlled trial. Lancet Oncol 6: 757-764.
10. Shoin K, et al (1991) Chick embryo assay as chemosensitivity test for malignant glioma. Jpn J Cancer Res 82: 1165-1170.
11. Endo Y, et al (1992) Experimental metastasis of oncogene-transformed NIH 3T3 cells in chick embryo. Jpn J Cancer Res 83: 274-280.
12. Nakayama S, et al (2008) TX-2152: a conformationally rigid and electron-rich diyne analogue of FTY720 with in vivo antiangiogenic activity. Bioorg Med Chem 16: 7705-7714.
13. Nishigori H, Mizumura M and Iwatsuru M (1992) The hen's fertile egg screening test (HEST): A comparison between the acute toxicity for chick embryos and rodents of 20 drugs. Cell Biol Toxicol 8: 255-265.
14. Saw CL, et al (2006) Enhanced photodynamic activity of hypericin by penetration enhancer N-methyl pyrrolidone formulations in the chick chorioallantoic membrane model. Cancer Lett 238: 104-110.
15. Zwadlo-Klarwasser G, et al (2001) The chorioallantoic membrane of the chick embryo as a simple model for the study of the angiogenic and inflammatory response to biomaterials. J Mater Sci Mater Med 12: 195-199.
16. Vargas A, et al (2007) The chick embryo and its chorioallantoic membrane (CAM) for the in vivo evaluation of drug delivery systems. Adv Drug Deliv Rev 59: 1162-1176.
17. Weber WT and Mausner R (1977) Migration patterns of avian embryonic bone marrow cells and their differentiation to functional T and B cells. Adv Exp Med Biol 88: 47-59.
18. Kiep L (2005) Metabolism of xenobiotics in the incubated hen's egg: investigations with ethyl 4-hydroxybenzoate. ALTEX 22: 135-141.
19. Tomosiunas V and Padarauskas A (2009) Ultra performance liquid chromatography-tandem mass spectrometry for the determination of 5-nitroimidazoles and their metabolites in egg. Cent Eur J Chem 7: 267-273.
20. Drzymala RE, et al (2008) A phase I-B trial of the radiosensitizer: etanidazole (SR-2508) with radiosurgery for the treatment of recurrent previously irradiated primary brain tumors or brain metastases (RTOG Study 95-02). Radiother Oncol 87: 89-92.
21. Xavier S, et al (2006) The vitamin-like dietary supplement para-aminobenzoic acid enhances the antitumor activity of ionizing radiation. Int J Radiation Oncology Biol Phys 65: 517-527.
22. Murayama C, et al (1992) Radiosensitization by 2-nitroimidazole nucleoside analog RP-170:Radiosensitizing effects under both intravenous and oral administration. Int J Radiation Oncology Biol Phys 22: 557-560.
23. Herman TS, et al (1990) Addition of 2-nitroimidazole radiosensitizers to cis-diamminedichloroplatinum(II) with radiation and with or without hyperthermia in the murine FSaIIC fibrosarcoma. Cancer Res 50: 2734-2740.
24. Grahan D and Hamilton KF (1957) Genetic variation in the acute lethal response of four inbred mouse strains to whole body X-irradiation. Genetics 42: 189-198.
25. Shintani S, et al (2006) Anti-tumor effect of radiation response by combined treatment with angiogenesis inhibitor, TNP-470, in oral squamous cell carcinoma. Oral Oncol 42: 66-72.
26. Cariveau MJ, et al (2008) Clofarabine acts as radiosensitizer in vitro and in vivo by interfering with DNA response. Int J Radiation Oncology Biol Phys 70: 213-220.
27. Jensen MM, et al (2008) Tumor volume in subcutaneous mouse xenografts measured by microCT is more accurate and reproducible than determined by 18F-FDG-microPET or external caliper. BMC Med Imaging 16: 8-16.
28. Uchida H, et al (1987) Response to antitumor agents of murine transplantable tumors implanted onto chorioallantoic membrane of chick embryo. Jpn J Cancer Res 78: 729-736.