Anti-tumor effect of radiation response by combined treatment with angiogenesis inhibitor, TNP-470, in oral squamous cell carcinoma

Oral Oncology

Volumn 42, Issue 1, 2006, Pages 65-71

  Shintani, Satoru ^a   Li, Chunnan ^a   Mihara, Mariko ^a   Klosek, Sebastian K ^a   Terakado, Nagaaki ^a   Hino, Satoshi ^a   Hamakawa, Hiroyuki ^a  

^a EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Angiogenesis; Angiogenesis inhibitor; Oral cancer; Radiation; TNP 470

Indexed keywords

ANGIOGENESIS INHIBITOR; FUMAGILLOL CHLOROACETYLCARBAMATE;

AIR SAC; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CANCER RADIOTHERAPY; CELL STRAIN KB; CONTROLLED STUDY; EVALUATION; IRRADIATION; MALE; MOUSE; MOUTH CARCINOMA; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; RADIATION DOSE; RADIATION RESPONSE; SQUAMOUS CELL CARCINOMA; TUMOR GROWTH;

EID: 29244470563     PISSN: 13688375     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2005.06.010     Document Type: Article

References (21)

1. J. Folkman What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 82 1 1990 4 6
2. J. Denekamp Angiogenesis, neovascular proliferation and vascular pathophysiology as targets for cancer therapy Br J Radiol 66 783 1993 181 196
3. V. Castronovo, and D. Belotti TNP-470 (AGM-1470): mechanisms of action and early clinical development Eur J Cancer 32A 14 1996 2520 2527
4. M. Emoto, M. Ishiguro, H. Iwasaki, M. Kikuchi, and T. Kawarabayashi Effect of angiogenesis inhibitor TNP-470 on the growth, blood flow, and microvessel density in xenografts of human uterine carcinosarcoma in nude mice Gynecol Oncol 89 1 2003 88 94
5. T. Kalebic, M. Tsokos, and L.J. Helman Suppression of rhabdomyosarcoma growth by fumagillin analog TNP-470 Int J Cancer 68 5 1996 596 599
6. R.E. Alcalde, S. Shintani, Y. Yoshihama, and T. Matsumura Cell proliferation and tumor angiogenesis in oral squamous cell carcinoma Anticancer Res 15 4 1995 1417 1422
7. S. Shintani, C. Li, T. Ishikawa, M. Mihara, K. Nakashiro, and H. Hamakawa Expression of vascular endothelial growth factor A, B, C, and D in oral squamous cell carcinoma Oral Oncol 40 1 2004 13 20
8. S. Shintani, A. Kiyota, M. Mihara, Y. Nakahara, N. Terakado, Y. Ueyama, and T. Matsumura Association of preoperative radiation effect with tumor angiogenesis and vascular endothelial growth factor in oral squamous cell carcinoma Jpn J Cancer Res 91 2000 1051 1057
9. B.A. Teicher, S.A. Holden, G. Ara, T. Korbut, and K. Menon Comparison of several antiangiogenic regimens alone and with cytotoxic therapies in the Lewis lung carcinoma Cancer Chemother Pharmacol 38 2 1996 169 177
10. E.L. Lund, L. Bastholm, and P.E. Kristjansen Therapeutic synergy of TNP-470 and ionizing radiation: effects on tumor growth, vessel morphology, and angiogenesis in human glioblastoma multiforme xenografts Clin Cancer Res 6 3 2000 971 978
11. T. Oikawa, M. Sasaki, M. Inoue, M. Shimamura, H. Kuboki, and S. Hirano Effect of cytogenin, a novel microbial product, on embryonic and tumor cell-induced angiogenic response in vivo Anticancer Res 17 3C 1997 1881 1886
12. N. Weidner, J.P. Semple, W.R. Welch, and J. Folkman Tumor angiogenesis and metastasis-correlation in invasive breast carcinoma New Engl J Med 324 1 1991 1 8
13. H. Brem, and J. Folkman Analysis of experimental antiangiogenic therapy J Pediatr Surg 28 3 1993 445 451
14. M. Kusaka, K. Sudo, and E. Matsutani Cytostatic inhibition of endothelial cell growth by the angiogenesis inhibitor TNP-470 (AGM-1470) Br J Cancer 69 2 1994 212 216
15. N. Ueda, N. Kamata, E. Hayashi, K. Yokoyama, T. Hoteiya, and M. Nagayama Effects of an anti-angiogenic agent, TNP-470, on the growth of oral squamous cell carcinomas Oral Oncol 35 6 1999 554 560
16. D. Chaplin, G.R. Pettit, and S.A. Hill Anti-vascular approaches to solid tumor therapy: evaluation of combretastatin A-4 phosphates Anticancer Res 19 1A 1999 189 196
17. H.J. Mauceri, N.N. Hanna, M.A. Beckett, D.H. Gorski, M.J. Staba, and K.A. Stellato Combined effects of angiostatin and ionizing radiation in antitumour therapy Nature 394 6690 1998 287 291
18. H. Satoh, H. Ishikawa, M. Fujimoto, M. Fujiwara, Y.T. Yamashita, and T. Yazawa Combined effects of TNP-470 and taxol in human non-small cell lung cancer cell lines Anticancer Res 18 2A 1998 1027 1030
19. B.A. Teicher, S.A. Holden, G. Ara, E.A. Sotomayor, Z.D. Huang, and Y.N. Chen Potentiation of cytotoxic cancer therapies by TNP-470 alone and with other anti-angiogenic agents Int J Cancer 57 6 1994 920 925
20. R. Murata, Y. Nishimura, and M. Hiraoka An antiangiogenic agent (TNP-470) inhibited reoxygenation during fractionated radiotherapy of murine mammary carcinoma Int J Radiat Oncol Biol Phys 37 5 1997 1107 1113
21. B.A. Teicher, S.A. Holden, N.P. Dupuis, Y. Kakeji, M. Ikebe, and Y. Emi Potentiation of cytotoxic therapies by TNP-470 and minocycline in mice bearing EMT-6 mammary carcinoma Breast Cancer Res Treat 36 2 1995 227 236