메뉴 건너뛰기




Volumn 7, Issue 2, 2011, Pages 155-164

Ustekinumab for the treatment of psoriasis

Author keywords

biological therapy; psoriasis; ustekinumab

Indexed keywords

CUTANEOUS LYMPHOCYTE ASSOCIATED ANTIGEN; ETANERCEPT; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 2; INTERLEUKIN 22; INTERLEUKIN 23; INTERLEUKIN 6; PLACEBO; TUMOR NECROSIS FACTOR ALPHA; USTEKINUMAB;

EID: 79953117927     PISSN: 1744666X     EISSN: None     Source Type: Journal    
DOI: 10.1586/eci.11.4     Document Type: Article
Times cited : (10)

References (65)
  • 1
    • 34447539622 scopus 로고    scopus 로고
    • Pathogenesis and clinical features of psoriasis
    • DOI 10.1016/S0140-6736(07)61128-3, PII S0140673607611283
    • Griffiths CE, Barker JN. Pathogenesis and clinical features of psoriasis. Lancet 370(9583), 263-271 (2007). (Pubitemid 47069537)
    • (2007) Lancet , vol.370 , Issue.9583 , pp. 263-271
    • Griffiths, C.E.1    Barker, J.N.2
  • 3
    • 33751181855 scopus 로고    scopus 로고
    • Increased prevalence of the metabolic syndrome in patients with moderate to severe psoriasis
    • Sommer DM, Jenisch S, Suchan M, Christophers E, Weichenthal M. Increased prevalence of the metabolic syndrome in patients with moderate to severe psoriasis. Arch. Dermatol. Res. 298(7), 321-328 (2006).
    • (2006) Arch. Dermatol. Res. , vol.298 , Issue.7 , pp. 321-328
    • Sommer, D.M.1    Jenisch, S.2    Suchan, M.3    Christophers, E.4    Weichenthal, M.5
  • 5
    • 0041692739 scopus 로고    scopus 로고
    • The interrelationship between sex, susceptibility factors, and outcome in ankylosing spondylitis and its associated disorders including inflammatory bowel disease, psoriasis, and iritis
    • Brophy S, Taylor G, Blake D, Calin A. The interrelationship between sex, susceptibility factors, and outcome in ankylosing spondylitis and its associated disorders including inflammatory bowel disease, psoriasis, and iritis. J. Rheumatol. 30(9), 2054-2058 (2003). (Pubitemid 37075561)
    • (2003) Journal of Rheumatology , vol.30 , Issue.9 , pp. 2054-2058
    • Brophy, S.1    Taylor, G.2    Blake, D.3    Calin, A.4
  • 8
    • 43449111187 scopus 로고    scopus 로고
    • Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)
    • DOI 10.1016/S0140-6736(08)60725-4, PII S0140673608607254
    • Leonardi CL, Kimball AB, Papp KA et al. Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, doubleblind, placebo-controlled trial (PHOENIX 1). Lancet 371(9625), 1665-1674 (2008). Phase III study of ustekinumab for the treatment of chronic plaque psoriasis. (Pubitemid 351671883)
    • (2008) The Lancet , vol.371 , Issue.9625 , pp. 1665-1674
    • Leonardi, C.L.1    Kimball, A.B.2    Papp, K.A.3    Yeilding, N.4    Guzzo, C.5    Wang, Y.6    Li, S.7    Dooley, L.T.8    Gordon, K.B.9
  • 9
    • 43449139402 scopus 로고    scopus 로고
    • Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2)
    • DOI 10.1016/S0140-6736(08)60726-6, PII S0140673608607266
    • Papp KA, Langley RG, Lebwohl M et al. Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2). Lancet 371(9625), 1675-1684 (2008). A Phase III study of ustekinumab for the treatment of chronic plaque psoriasis. (Pubitemid 351671884)
    • (2008) The Lancet , vol.371 , Issue.9625 , pp. 1675-1684
    • Papp, K.A.1    Langley, R.G.2    Lebwohl, M.3    Krueger, G.G.4    Szapary, P.5    Yeilding, N.6    Guzzo, C.7    Hsu, M.-C.8    Wang, Y.9    Li, S.10    Dooley, L.T.11    Reich, K.12
  • 10
    • 57349145907 scopus 로고    scopus 로고
    • No association between polymorphisms in the interleukin-15 gene and early-onset psoriasis in a UK cohort suggests heterogeneity for this susceptibility locus identified in Chinese psoriasis patients
    • Smith RL, Eyre S, Warren RB, Young HS, Griffiths CE, Worthington J. No association between polymorphisms in the interleukin-15 gene and early-onset psoriasis in a UK cohort suggests heterogeneity for this susceptibility locus identified in Chinese psoriasis patients. J. Invest. Dermatol. 128(12), 2904-2905 (2008).
    • (2008) J. Invest. Dermatol. , vol.128 , Issue.12 , pp. 2904-2905
    • Smith, R.L.1    Eyre, S.2    Warren, R.B.3    Young, H.S.4    Griffiths, C.E.5    Worthington, J.6
  • 11
    • 77951838972 scopus 로고    scopus 로고
    • Positive treatment effects of ustekinumab in psoriasis: Analysis of lesional and systemic parameters
    • Reddy M, Torres G, McCormick T et al. Positive treatment effects of ustekinumab in psoriasis: Analysis of lesional and systemic parameters. J. Dermatol. 37(5), 413-425 (2007).
    • (2007) J. Dermatol. , vol.37 , Issue.5 , pp. 413-425
    • Reddy, M.1    Torres, G.2    McCormick, T.3
  • 13
    • 62449205652 scopus 로고    scopus 로고
    • Long-term control of recalcitrant psoriasis with combination infliximab and methotrexate
    • Warren RB, Brown BC, Carmichael AJ, Griffiths CE. Long-term control of recalcitrant psoriasis with combination infliximab and methotrexate. Clin. Exp. Dermatol. 34(3), 415-416 (2009).
    • (2009) Clin. Exp. Dermatol. , vol.34 , Issue.3 , pp. 415-416
    • Warren, R.B.1    Brown, B.C.2    Carmichael, A.J.3    Griffiths, C.E.4
  • 14
    • 57649170604 scopus 로고    scopus 로고
    • Biologic therapies for psoriasis: Practical experience in a U.K. tertiary referral centre
    • Warren RB, Brown BC, Lavery D, Ashcroft DM, Griffiths CE. Biologic therapies for psoriasis: Practical experience in a U.K. tertiary referral centre. Br. J. Dermatol. 160(1), 162-169 (2009).
    • (2009) Br. J. Dermatol. , vol.160 , Issue.1 , pp. 162-169
    • Warren, R.B.1    Brown, B.C.2    Lavery, D.3    Ashcroft, D.M.4    Griffiths, C.E.5
  • 16
    • 78249281659 scopus 로고    scopus 로고
    • Ustekinumab in the treatment of palmoplantar pustulosis
    • Gerdes S, Franke J, Domm S, Mrowietz U. Ustekinumab in the treatment of palmoplantar pustulosis. Br. J. Dermatol. 163(5), 1116-1118 (2010).
    • (2010) Br. J. Dermatol. , vol.163 , Issue.5 , pp. 1116-1118
    • Gerdes, S.1    Franke, J.2    Domm, S.3    Mrowietz, U.4
  • 17
    • 77955891631 scopus 로고    scopus 로고
    • Treatment of pityriasis rubra pilaris with ustekinumab
    • Wohlrab J, Kreft B. Treatment of pityriasis rubra pilaris with ustekinumab. Br. J. Dermatol. 163(3), 655-656 (2010).
    • (2010) Br. J. Dermatol. , vol.163 , Issue.3 , pp. 655-656
    • Wohlrab, J.1    Kreft, B.2
  • 18
    • 79953104416 scopus 로고    scopus 로고
    • Severe pyoderma gangrenosum unresponsive to etanercept and adalimumab
    • DOI:10.3109/09546631003797106, Epub ahead of print
    • Kleinpenning MM, Langewouters AM, Van De Kerkhof PC, Greebe RJ. Severe pyoderma gangrenosum unresponsive to etanercept and adalimumab. J. Dermatolog. Treat. DOI:10.3109/09546631003797106 (2010) (Epub ahead of print).
    • (2010) J. Dermatolog. Treat.
    • Kleinpenning, M.M.1    Langewouters, A.M.2    Van De Kerkhof, P.C.3    Greebe, R.J.4
  • 21
    • 34249039292 scopus 로고    scopus 로고
    • A phase 1, double-blind, placebo-controlled study evaluating single subcutaneous administrations of a human interleukin-12/23 monoclonal antibody in subjects with plaque psoriasis
    • DOI 10.1185/030079907X182112
    • Gottlieb AB, Cooper KD, McCormick TS et al. A Phase 1, double-blind, placebocontrolled study evaluating single subcutaneous administrations of a human interleukin-12/23 monoclonal antibody in subjects with plaque psoriasis. Curr. Med. Res. Opin. 23(5), 1081-1092 (2007). Phase I study of ustekinumab for the treatment of chronic plaque psoriasis. (Pubitemid 46799592)
    • (2007) Current Medical Research and Opinion , vol.23 , Issue.5 , pp. 1081-1092
    • Gottlieb, A.B.1    Cooper, K.D.2    McCormick, T.S.3    Toichi, E.4    Everitt, D.E.5    Frederick, B.6    Zhu, Y.7    Pendley, C.E.8    Graham, M.A.9    Mascelli, M.A.10
  • 22
    • 58849118867 scopus 로고    scopus 로고
    • Population pharmacokinetic modeling of ustekinumab, a human monoclonal antibody targeting IL-12/23p40, in patients with moderate to severe plaque psoriasis
    • Zhu Y, Hu C, Lu M et al. Population pharmacokinetic modeling of ustekinumab, a human monoclonal antibody targeting IL-12/23p40, in patients with moderate to severe plaque psoriasis. J. Clin. Pharmacol. 49(2), 162-175 (2009).
    • (2009) J. Clin. Pharmacol. , vol.49 , Issue.2 , pp. 162-175
    • Zhu, Y.1    Hu, C.2    Lu, M.3
  • 23
    • 0018099294 scopus 로고
    • Severe psoriasis - oral therapy with a new retinoid
    • Fredriksson T, Pettersson U. Severe psoriasis - oral therapy with a new retinoid. Dermatologica 157(4), 238-244 (1978). (Pubitemid 8387357)
    • (1978) Dermatologica , vol.157 , Issue.4 , pp. 238-244
    • Fredriksson, T.1    Pettersson, U.2
  • 24
    • 20444466784 scopus 로고    scopus 로고
    • Decision points for the initiation of systemic treatment for psoriasis
    • DOI 10.1016/j.jaad.2005.03.050, PII S0190962205010303
    • Feldman SR, Koo JY, Menter A, Bagel J. Decision points for the initiation of systemic treatment for psoriasis. J. Am. Acad. Dermatol. 53(1), 101-107 (2005). (Pubitemid 40826702)
    • (2005) Journal of the American Academy of Dermatology , vol.53 , Issue.1 , pp. 101-107
    • Feldman, S.R.1    Koo, J.Y.M.2    Menter, A.3    Bagel, J.4
  • 25
    • 0028332995 scopus 로고
    • Dermatology Life Quality Index (DLQI) - A simple practical measure for routine clinical use
    • DOI 10.1111/j.1365-2230.1994.tb01167.x
    • Finlay AY, Khan GK. Dermatology Life Quality Index (DLQI) - a simple practical measure for routine clinical use. Clin. Exp. Dermatol. 19(3), 210-216 (1994). (Pubitemid 24194579)
    • (1994) Clinical and Experimental Dermatology , vol.19 , Issue.3 , pp. 210-216
    • Finlay, A.Y.1    Khan, G.K.2
  • 26
    • 0020527558 scopus 로고
    • The hospital anxiety and depression scale
    • Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr. Scand. 67(6), 361-370 (1983). (Pubitemid 13098606)
    • (1983) Acta Psychiatrica Scandinavica , vol.67 , Issue.6 , pp. 361-370
    • Zigmond, A.S.1    Snaith, R.P.2
  • 27
    • 0026877917 scopus 로고
    • The MOS 36-item Short-Form health survey (SF-36). I. Conceptual framework and item selection
    • Ware JE Jr, Sherbourne CD. The MOS 36-item Short-Form health survey (SF-36). I. Conceptual framework and item selection. Med. Care 30(6), 473-483 (1992).
    • (1992) Med. Care , vol.30 , Issue.6 , pp. 473-483
    • Ware Jr., J.E.1    Sherbourne, C.D.2
  • 29
    • 74249094930 scopus 로고    scopus 로고
    • Comparison of ustekinumab and etanercept for moderate-to-severe psoriasis
    • Phase III clinical study directly comparing ustekinumab and etanercept for the treatment of chronic plaque psoriasis
    • Griffiths CE, Strober BE, van de Kerkhof P et al. Comparison of ustekinumab and etanercept for moderate-to-severe psoriasis. N. Engl. J. Med. 362(2), 118-128 (2010). Phase III clinical study directly comparing ustekinumab and etanercept for the treatment of chronic plaque psoriasis.
    • (2010) N. Engl. J. Med. , vol.362 , Issue.2 , pp. 118-128
    • Griffiths, C.E.1    Strober, B.E.2    Van De Kerkhof, P.3
  • 30
    • 72749086156 scopus 로고    scopus 로고
    • Ustekinumab improves health-related quality of life in patients with moderate-tosevere psoriasis: Results from the PHOENIX 1 trial
    • Lebwohl M, Papp K, Han C et al. Ustekinumab improves health-related quality of life in patients with moderate-tosevere psoriasis: Results from the PHOENIX 1 trial. Br. J. Dermatol. 162(1), 137-146 (2010).
    • (2010) Br. J. Dermatol. , vol.162 , Issue.1 , pp. 137-146
    • Lebwohl, M.1    Papp, K.2    Han, C.3
  • 31
    • 77955921585 scopus 로고    scopus 로고
    • Ustekinumab significantly improves symptoms of anxiety, depression, and skin-related quality of life in patients with moderate-to-severe psoriasis: Results from a randomized, double-blind, placebocontrolled Phase III trial
    • Langley RG, Feldman SR, Han C et al. Ustekinumab significantly improves symptoms of anxiety, depression, and skin-related quality of life in patients with moderate-to-severe psoriasis: Results from a randomized, double-blind, placebocontrolled Phase III trial. J. Am. Acad. Dermatol. 63(3), 457-465 (2010).
    • (2010) J. Am. Acad. Dermatol. , vol.63 , Issue.3 , pp. 457-465
    • Langley, R.G.1    Feldman, S.R.2    Han, C.3
  • 32
    • 12244252752 scopus 로고    scopus 로고
    • The plasma levels of interleukin-12 in schizophrenia, major depression, and bipolar mania: Effects of psychotropic drugs
    • DOI 10.1038/sj.mp.4001084
    • Kim YK, Suh IB, Kim H et al. The plasma levels of interleukin-12 in schizophrenia, major depression, and bipolar mania: Effects of psychotropic drugs. Mol. Psychiatry 7(10), 1107-1114 (2002). (Pubitemid 36044270)
    • (2002) Molecular Psychiatry , vol.7 , Issue.10 , pp. 1107-1114
    • Kim, Y.-K.1    Suh, I.-B.2    Kim, H.3    Han, C.-S.4    Lim, C.-S.5    Choi, S.-H.6    Licinio, J.7
  • 34
    • 60249084148 scopus 로고    scopus 로고
    • Ustekinumab, a human interleukin 12/23 monoclonal antibody, for psoriatic arthritis: Randomised, double-blind, placebocontrolled, crossover trial
    • Phase II study of ustekinumab for the treatment of psoriatic arthritis
    • Gottlieb A, Menter A, Mendelsohn A et al. Ustekinumab, a human interleukin 12/23 monoclonal antibody, for psoriatic arthritis: Randomised, double-blind, placebocontrolled, crossover trial. Lancet 373(9664), 633-640 (2009). Phase II study of ustekinumab for the treatment of psoriatic arthritis.
    • (2009) Lancet , vol.373 , Issue.9664 , pp. 633-640
    • Gottlieb, A.1    Menter, A.2    Mendelsohn, A.3
  • 35
    • 0346458589 scopus 로고    scopus 로고
    • Assessment of patients with psoriatic arthritis: A review of currently available measures
    • DOI 10.1002/art.11417
    • Gladman DD, Helliwell P, Mease PJ, Nash P, Ritchlin C, Taylor W. Assessment of patients with psoriatic arthritis: A review of currently available measures. Arthritis Rheum. 50(1), 24-35 (2004). (Pubitemid 38084284)
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.1 , pp. 24-35
    • Gladman, D.D.1    Helliwell, P.2    Mease, P.J.3    Nash, P.4    Ritchlin, C.5    Taylor, W.6
  • 36
    • 77956749789 scopus 로고    scopus 로고
    • Effect of ustekinumab on physical function and health-related quality of life in patients with psoriatic arthritis: A randomized, placebo-controlled, Phase II trial
    • Kavanaugh A, Menter A, Mendelsohn A, Shen YK, Lee S, Gottlieb AB. Effect of ustekinumab on physical function and health-related quality of life in patients with psoriatic arthritis: A randomized, placebo-controlled, Phase II trial. Curr. Med. Res. Opin. 26(10), 2385-2392 (2010).
    • (2010) Curr. Med. Res. Opin. , vol.26 , Issue.10 , pp. 2385-2392
    • Kavanaugh, A.1    Menter, A.2    Mendelsohn, A.3    Shen, Y.K.4    Lee, S.5    Gottlieb, A.B.6
  • 37
    • 77955751351 scopus 로고    scopus 로고
    • Impact of weight on the efficacy and safety of ustekinumab in patients with moderate to severe psoriasis: Rationale for dosing recommendations
    • Lebwohl M, Yeilding N, Szapary P et al. Impact of weight on the efficacy and safety of ustekinumab in patients with moderate to severe psoriasis: Rationale for dosing recommendations. J. Am. Acad. Dermatol. 63(4), 571-579 (2010).
    • (2010) J. Am. Acad. Dermatol. , vol.63 , Issue.4 , pp. 571-579
    • Lebwohl, M.1    Yeilding, N.2    Szapary, P.3
  • 38
    • 77951537732 scopus 로고    scopus 로고
    • Can primary immunodeficiencies help to provide insights into infectious risks of therapeutic antibodies?
    • Marodi L, Casanova JL. Can primary immunodeficiencies help to provide insights into infectious risks of therapeutic antibodies? Nat. Rev. Immunol. 10(5), 299-300 (2010).
    • (2010) Nat. Rev. Immunol. , vol.10 , Issue.5 , pp. 299-300
    • Marodi, L.1    Casanova, J.L.2
  • 39
    • 39249084392 scopus 로고    scopus 로고
    • Novel primary immunodeficiencies revealed by the investigation of paediatric infectious diseases
    • Bustamante J, Boisson-Dupuis S, Jouanguy E et al. Novel primary immunodeficiencies revealed by the investigation of paediatric infectious diseases. Curr. Opin. Immunol. 20(1), 39-48 (2008).
    • (2008) Curr. Opin. Immunol. , vol.20 , Issue.1 , pp. 39-48
    • Bustamante, J.1    Boisson-Dupuis, S.2    Jouanguy, E.3
  • 40
    • 55149102403 scopus 로고    scopus 로고
    • Inborn errors of interferon (IFN)-mediated immunity in humans: Insights into the respective roles of IFN-a/b, IFN-g, and IFN-l in host defense
    • Zhang SY, Boisson-Dupuis S, Chapgier A et al. Inborn errors of interferon (IFN)-mediated immunity in humans: Insights into the respective roles of IFN-a/b, IFN-g, and IFN-l in host defense. Immunol. Rev. 226, 29-40 (2008).
    • (2008) Immunol. Rev. , vol.226 , pp. 29-40
    • Zhang, S.Y.1    Boisson-Dupuis, S.2    Chapgier, A.3
  • 41
    • 38449083851 scopus 로고    scopus 로고
    • Host genetics of mycobacterial diseases in mice and men: Forward genetic studies of BCG-osis and tuberculosis
    • Fortin A, Abel L, Casanova JL, Gros P. Host genetics of mycobacterial diseases in mice and men: Forward genetic studies of BCG-osis and tuberculosis. Ann. Rev. Genomics Hum. Genet. 8, 163-192 (2007).
    • (2007) Ann. Rev. Genomics Hum. Genet. , vol.8 , pp. 163-192
    • Fortin, A.1    Abel, L.2    Casanova, J.L.3    Gros, P.4
  • 43
    • 77957082219 scopus 로고    scopus 로고
    • Adalimumab for psoriasis: Practical experience in a U.K. tertiary referral centre
    • Warren RB, Brown BC, Lavery D, Griffiths CE. Adalimumab for psoriasis: Practical experience in a U.K. tertiary referral centre. Br. J. Dermatol. 163(4), 859-862 (2010).
    • (2010) Br. J. Dermatol. , vol.163 , Issue.4 , pp. 859-862
    • Warren, R.B.1    Brown, B.C.2    Lavery, D.3    Griffiths, C.E.4
  • 44
    • 71949087471 scopus 로고    scopus 로고
    • British Association of Dermatologists' guidelines for biologic interventions for psoriasis 2009
    • Smith CH, Anstey AV, Barker JN et al. British Association of Dermatologists' guidelines for biologic interventions for psoriasis 2009. Br. J. Dermatol. 161(5), 987-1019 (2009).
    • (2009) Br. J. Dermatol. , vol.161 , Issue.5 , pp. 987-1019
    • Smith, C.H.1    Anstey, A.V.2    Barker, J.N.3
  • 46
    • 47049122733 scopus 로고    scopus 로고
    • National Psoriasis Foundation consensus statement on screening for latent tuberculosis infection in patients with psoriasis treated with systemic and biologic agents
    • Doherty SD, Van Voorhees A, Lebwohl MG et al. National Psoriasis Foundation consensus statement on screening for latent tuberculosis infection in patients with psoriasis treated with systemic and biologic agents. J. Am. Acad. Dermatol. 59(2), 209-217 (2008).
    • (2008) J. Am. Acad. Dermatol. , vol.59 , Issue.2 , pp. 209-217
    • Doherty, S.D.1    Van Voorhees, A.2    Lebwohl, M.G.3
  • 47
    • 77950848197 scopus 로고    scopus 로고
    • Review of ustekinumab, an interleukin-12 and interleukin-23 inhibitor used for the treatment of plaque psoriasis
    • Koutruba N, Emer J, Lebwohl M. Review of ustekinumab, an interleukin-12 and interleukin-23 inhibitor used for the treatment of plaque psoriasis. Ther. Clin. Risk Manag. 6, 123-141 (2010).
    • (2010) Ther. Clin. Risk Manag. , vol.6 , pp. 123-141
    • Koutruba, N.1    Emer, J.2    Lebwohl, M.3
  • 49
    • 67649331684 scopus 로고    scopus 로고
    • Ustekinumab: A new option in psoriasis therapy
    • Chien AL, Elder JT, Ellis CN. Ustekinumab: A new option in psoriasis therapy. Drugs 69(9), 1141-1152 (2009).
    • (2009) Drugs , vol.69 , Issue.9 , pp. 1141-1152
    • Chien, A.L.1    Elder, J.T.2    Ellis, C.N.3
  • 50
    • 77956130043 scopus 로고    scopus 로고
    • Oesophageal squamous cell carcinoma in a young adult with IL-12R b 1 deficiency
    • Cardenes M, Angel-Moreno A, Fieschi C et al. Oesophageal squamous cell carcinoma in a young adult with IL-12R b 1 deficiency. J. Med. Genet. 47(9), 635-637 (2010).
    • (2010) J. Med. Genet. , vol.47 , Issue.9 , pp. 635-637
    • Cardenes, M.1    Angel-Moreno, A.2    Fieschi, C.3
  • 51
    • 48849087125 scopus 로고    scopus 로고
    • Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: A Phase II, double-blind, placebo-controlled, randomised, dose-ranging study
    • Segal BM, Constantinescu CS, Raychaudhuri A, Kim L, Fidelus-Gort R, Kasper LH. Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: A Phase II, double-blind, placebo-controlled, randomised, dose-ranging study. Lancet Neurol. 7(9), 796-804 (2008).
    • (2008) Lancet Neurol. , vol.7 , Issue.9 , pp. 796-804
    • Segal, B.M.1    Constantinescu, C.S.2    Raychaudhuri, A.3    Kim, L.4    Fidelus-Gort, R.5    Kasper, L.H.6
  • 53
    • 0029788704 scopus 로고    scopus 로고
    • IL-12 unmasks latent autoimmune disease in resistant mice
    • Segal BM, Shevach EM. IL-12 unmasks latent autoimmune disease in resistant mice. J. Exp. Med. 184(2), 771-775 (1996). (Pubitemid 26324133)
    • (1996) Journal of Experimental Medicine , vol.184 , Issue.2 , pp. 771-775
    • Segal, B.M.1    Shevach, E.M.2
  • 54
    • 0032976126 scopus 로고    scopus 로고
    • The role of interleukin 12 in the development of atherosclerosis in ApoE-deficient mice
    • Lee TS, Yen HC, Pan CC, Chau LY. The role of interleukin 12 in the development of atherosclerosis in ApoE-deficient mice. Arterioscler. Thromb. Vasc. Biol. 19(3), 734-742 (1999).
    • (1999) Arterioscler. Thromb. Vasc. Biol. , vol.19 , Issue.3 , pp. 734-742
    • Lee, T.S.1    Yen, H.C.2    Pan, C.C.3    Chau, L.Y.4
  • 58
    • 77954882667 scopus 로고    scopus 로고
    • Observational case series on a group of patients with severe psoriasis who failed to respond to antitumour necrosis factor a biologics and switched to ustekinumab
    • Downs AM. Observational case series on a group of patients with severe psoriasis who failed to respond to antitumour necrosis factor a biologics and switched to ustekinumab. Br. J. Dermatol. 163(2), 433-434 (2010).
    • (2010) Br. J. Dermatol. , vol.163 , Issue.2 , pp. 433-434
    • Downs, A.M.1
  • 59
    • 79953111225 scopus 로고    scopus 로고
    • Responses to ustekinumab in the anti-TNF agent-naive vs. anti-TNF agent-exposed patients with psoriasis vulgaris
    • DOI: 10.1111/j.1468-3083.2010.03914.x, Epub ahead of print
    • Clemmensen A, Spon M, Skov L, Zachariae C, Gniadecki R. Responses to ustekinumab in the anti-TNF agent-naive vs. anti-TNF agent-exposed patients with psoriasis vulgaris. J. Eur. Acad. Dermatol. Venereol. DOI: 10.1111/j.1468-3083. 2010.03914.x (2010) (Epub ahead of print).
    • (2010) J. Eur. Acad. Dermatol. Venereol.
    • Clemmensen, A.1    Spon, M.2    Skov, L.3    Zachariae, C.4    Gniadecki, R.5
  • 61
    • 58349083267 scopus 로고    scopus 로고
    • Outcomes of methotrexate therapy for psoriasis and relationship to genetic polymorphisms
    • Warren RB, Smith RL, Campalani E et al. Outcomes of methotrexate therapy for psoriasis and relationship to genetic polymorphisms. Br. J. Dermatol. 160(2), 438-441 (2009).
    • (2009) Br. J. Dermatol. , vol.160 , Issue.2 , pp. 438-441
    • Warren, R.B.1    Smith, R.L.2    Campalani, E.3
  • 62
    • 77950524086 scopus 로고    scopus 로고
    • The latest advances in pharmacogenetics and pharmacogenomics in the treatment of psoriasis
    • Ryan C, Menter A, Warren RB. The latest advances in pharmacogenetics and pharmacogenomics in the treatment of psoriasis. Mol. Diagn. Ther. 14(2), 81-93 (2010).
    • (2010) Mol. Diagn. Ther. , vol.14 , Issue.2 , pp. 81-93
    • Ryan, C.1    Menter, A.2    Warren, R.B.3
  • 64
    • 71749085498 scopus 로고    scopus 로고
    • Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes
    • e1-e395
    • Zaba LC, Suarez-Farinas M, Fuentes- Duculan J et al. Effective treatment of psoriasis with etanercept is linked to suppression of IL-17 signaling, not immediate response TNF genes. J. Allergy Clin. Immunol. 124(5), 1022-1010; e1-e395 (2009).
    • (2009) J. Allergy Clin. Immunol. , vol.124 , Issue.5 , pp. 1022-1010
    • Zaba, L.C.1    Suarez-Farinas, M.2    Fuentes- Duculan, J.3
  • 65
    • 70349736206 scopus 로고    scopus 로고
    • Double-blind, placebo-controlled, dose-escalation study to evaluate the pharmacologic effect of CP-690,550 in patients with psoriasis
    • Boy MG, Wang C, Wilkinson BE et al. Double-blind, placebo-controlled, dose-escalation study to evaluate the pharmacologic effect of CP-690,550 in patients with psoriasis. J. Invest. Dermatol. 129(9), 2299-2302 (2009).
    • (2009) J. Invest. Dermatol. , vol.129 , Issue.9 , pp. 2299-2302
    • Boy, M.G.1    Wang, C.2    Wilkinson, B.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.