Impact of β2 integrin deficiency on mouse natural killer cell development and function

Blood

Volumn 117, Issue 10, 2011, Pages 2874-2882

  Crozat, Karine ^a,b,c,d   Eidenschenk, Céline ^d,f   Jaeger, Baptiste N ^a,b,c   Krebs, Philippe ^d   Guia, Sophie ^a,b,c   Beutler, Bruce ^d   Vivier, Eric ^a,b,c,e   Ugolini, Sophie ^a,b,c  

^a CENTRE D IMMUNOLOGIE DE MARSEILLE LUMINY   (France)

^b INSERM   (France)

^c CNRS   (France)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

^e HÔPITAL DE LA CONCEPTION   (France)

^f GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTEGRIN; CD18 ANTIGEN; STEM CELL FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; CELL MATURATION; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; HUMAN; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULAR RECOGNITION; MOUSE; NATURAL KILLER CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION;

EID: 79953107336     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-10-315457     Document Type: Article

References (49)

1. Vivier E, Tomasello E, Baratin M, Walzer T, Ugolini S. Functions of natural killer cells. Nat Immunol. 2008;9(5):503-510. (Pubitemid 351560519)
2. Lanier LL. NK cell recognition. Annu Rev Immunol. 2005;23:225-274. (Pubitemid 40563170)
3. Bottino C, Moretta L, Moretta A. NK cell activating receptors and tumor recognition in humans. Curr Top Microbiol Immunol. 2006;298:175-182.
4. Vivier E, Nunes JA, Vely F. Natural killer cell signaling pathways. Science. 2004;306(5701):1517-1519. (Pubitemid 39564941)
5. Raulet DH, Vance RE. Self-tolerance of natural killer cells. Nat Rev Immunol. 2006;6(7):520-531. (Pubitemid 43980524)
6. Yokoyama WM, Kim S. How do natural killer cells find self to achieve tolerance? Immunity. 2006;24(3):249-257.
7. Brodin P, Karre K, Hoglund P. NK-cell education: not an on-off switch but a tunable rheostat. Trends Immunol. 2009;30(4):143-149.
8. Anfossi N, Andre P, Guia S, et al. Human NK-cell education by inhibitory receptors for MHC class I. Immunity. 2006;25(2):331-342. (Pubitemid 44224147)
9. Fernandez NC, Treiner E, Vance RE, Jamieson AM, Lemieux S, Raulet DH.Asubset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC molecules. Blood. 2005;105(11):4416-4423. (Pubitemid 40720789)
10. Kim S, Poursine-Laurent J, Truscott SM, et al. Licensing of natural killer cells by host major histocompatibility complex class I molecules. Nature. 2005;436(7051):709-713. (Pubitemid 41117274)
11. Lucas M, Schachterle W, Oberle K, Aichele P, Diefenbach A. Dendritic cells prime natural killer cells by trans-presenting interleukin 15. Immunity. 2007;26(4):503-517. (Pubitemid 46602996)
12. Chaix J, Tessmer MS, Hoebe K, et al. Cutting edge: Priming of NK cells by IL-18. J Immunol. 2008;181(3):1627-1631.
13. Yokoyama WM, Kim S, French AR. The dynamic life of natural killer cells. Annu Rev Immunol. 2004;22:405-429. (Pubitemid 38680428)
14. Kim S, Iizuka K, Kang HS, et al. In vivo developmental stages in murine natural killer cell maturation. Nat Immunol. 2002;3:523-528.
15. Hayakawa Y, Smyth MJ. CD27 dissects mature NK cells into two subsets with distinct responsiveness and migratory capacity. J Immunol. 2006; 176(3):1517-1524. (Pubitemid 43134295)
16. Luo BH, Springer TA. Integrin structures and conformational signaling. Curr Opin Cell Biol. 2006;18(5):579-586.
17. Pribila JT, Quale AC, Mueller KL, Shimizu Y. Integrins and T cell-mediated immunity. Annu Rev Immunol. 2004;22:157-180. (Pubitemid 38680421)
18. Shier P, Otulakowski G, Ngo K, et al. Impaired immune responses toward alloantigens and tumor cells but normal thymic selection in mice deficient in the beta2 integrin leukocyte function-associated antigen-1. J Immunol. 1996;157(12):5375-5386. (Pubitemid 126448956)
19. Matsumoto G, Nghiem MP, Nozaki N, Schmits R, Penninger JM. Cooperation between CD44 and LFA-1/CD11a adhesion receptors in lymphokine-activated killer cell cytotoxicity. J Immunol. 1998;160(12):5781-5789. (Pubitemid 28298035)
20. Matsumoto G, Omi Y, Lee U, Nishimura T, Shindo J, Penninger JM. Adhesion mediated by LFA-1 is required for efficient IL-12-induced NK and NKT cell cytotoxicity. Eur J Immunol. 2000;30(12):3723-3731. (Pubitemid 32005247)
21. Blasius AL, Barchet W, Cella M, Colonna M. Development and function of murine B220+ CD11c+NK1.1+ cells identify them as a subset of NK cells. J Exp Med. 2007;204(11):2561-2568. (Pubitemid 350044782)
22. Wu H, Rodgers JR, Perrard XY, et al. Deficiency of CD11b or CD11d results in reduced staphylococcal enterotoxin-induced T cell response and T cell phenotypic changes. J Immunol. 2004;173(1):297-306. (Pubitemid 38797354)
23. Hoebe K, Du X, Georgel P, et al. Identification of Lps2 as a key transducer of MyD88-independent TIR signalling. Nature. 2003;424(6950):743-748. (Pubitemid 37021696)
24. Crozat K, Georgel P, Rutschmann S, et al. Analysis of the MCMV resistome by ENU mutagenesis. Mamm Genome. 2006;17(5):398-406. (Pubitemid 44011965)
25. Ruzek MC, Miller AH, Opal SM, Pearce BD, Biron CA. Characterization of early cytokine responses and an interleukin (IL)-6-dependent pathway of endogenous glucocorticoid induction during murine cytomegalovirus infection. J Exp Med. 1997;185(7):1185-1192. (Pubitemid 27172899)
26. Chiossone L, Chaix J, Fuseri N, Roth C, Vivier E, Walzer T. Maturation of mouse NK cells is a 4-stage developmental program. Blood. 2009;113(22):5488- 5496.
27. Crozat K, Hoebe K, Ugolini S, et al. Jinx, an MCMV susceptibility phenotype caused by disruption of Unc13d: a mouse model of type 3 familial hemophagocytic lymphohistiocytosis. J Exp Med. 2007;204(4):853-863. (Pubitemid 46631614)
28. Shi M, Foo SY, Tan SM, Mitchell EP, Law SK, Lescar J. A structural hypothesis for the transition between bent and extended conformations of the leukocyte beta2 integrins. J Biol Chem. 2007;282(41):30198-30206. (Pubitemid 350035258)
29. Xiao T, Takagi J, Coller BS, Wang JH, Springer TA. Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics. Nature. 2004;432(7013):59-67.
30. Mould AP, Humphries MJ. Regulation of integrin function through conformational complexity: not simply a knee-jerk reaction? Curr Opin Cell Biol. 2004;16(5):544-551.
31. Di Santo JP. Natural killer cell developmental pathways: a question of balance. Annu Rev Immunol. 2006;24:257-286.
32. Sola C, Andre P, Lemmers C, et al. Genetic and antibody-mediated reprogramming of natural killer cell missing-self recognition in vivo. Proc Natl Acad Sci U S A. 2009;106(31):12879-12884.
33. Lee SH, Miyagi T, Biron CA. Keeping NK cells in highly regulated antiviral warfare. Trends Immunol. 2007;28(6):252-259. (Pubitemid 46810349)
34. Scalzo AA, Fitzgerald NA, Wallace CR, et al. The effect of the Cmv-1 resistance gene, which is linked to the natural killer cell gene complex, is mediated by natural killer cells. J Immunol. 1992;149(2):581-589.
35. Welsh RM, Brubaker JO, Vargas-Cortes M, O'Donnell CL. Natural killer (NK) cell response to virus infections in mice with severe combined immunodeficiency. The stimulation of NK cells and the NK cell-dependent control of virus infections occur independently of T and B cell function. J Exp Med. 1991;173(5):1053-1063.
36. Scalzo AA, Corbett AJ, Rawlinson WD, Scott GM, Degli-Esposti MA. The interplay between host and viral factors in shaping the outcome of cytomegalovirus infection. Immunol Cell Biol. 2007;85(1):46-54. (Pubitemid 46067321)
37. Arase H, Mocarski ES, Campbell AE, Hill AB, Lanier LL. Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors. Science. 2002;296(5571):1323-1326. (Pubitemid 34522789)
38. Vidal SM, Lanier LL. NK cell recognition of mouse cytomegalovirus- infected cells. Curr Top Microbiol Immunol. 2006;298:183-206.
39. Smith HR, Heusel JW, Mehta IK, et al. Recognition of a virus-encoded ligand by a natural killer cell activation receptor. Proc Natl Acad Sci U S A. 2002;99(13):8826-8831. (Pubitemid 34693643)
40. Allavena P, Paganin C, Martin-Padura I, et al. Molecules and structures involved in the adhesion of natural killer cells to vascular endothelium. J Exp Med. 1991;173(2):439-448.
41. Barber DF, Faure M, Long EO. LFA-1 contributes an early signal for NK cell cytotoxicity. J Immunol. 2004;173(6):3653-3659. (Pubitemid 39280725)
42. Donskov F, Basse PH, Hokland M. Expression and function of LFA-1 on A-NK and T-LAK cells: role in tumor target killing and migration into tumor tissue. Nat Immun. 1996-1997;15(2-3):134-146. (Pubitemid 27100004)
43. Bryceson YT, March ME, Barber DF, Ljunggren HG, Long EO. Cytolytic granule polarization and degranulation controlled by different receptors in resting NK cells. J Exp Med. 2005;202(7):1001-1012. (Pubitemid 41396899)
44. Bryceson YT, Ljunggren HG, Long EO. Minimal requirement for induction of natural cytotoxicity and intersection of activation signals by inhibitory receptors. Blood. 2009;114(13):2657-2666.
45. Tay CH, Welsh RM, Brutkiewicz RR. NK cell response to viral infections in beta 2-microglobulin-deficient mice. J Immunol. 1995;154(2):780-789.
46. Sun JC, Lanier LL. Cutting edge: viral infection breaks NK cell tolerance to "missing self". J Immunol. 2008;181(11):7453-7457.
47. Messingham KA, Badovinac VP, Harty JT. Deficient anti-listerial immunity in the absence of perforin can be restored by increasing memory CD8+ T cell numbers. J Immunol. 2003;171(8):4254-4262. (Pubitemid 37238703)
48. Castriconi R, Dondero A, Cantoni C, et al. Functional characterization of natural killer cells in type I leukocyte adhesion deficiency. Blood. 2007;109(11):4873-4881. (Pubitemid 46827784)
49. Scharffetter-Kochanek K, Lu H, Norman K, et al. Spontaneous skin ulceration and defective T cell function in CD18 null mice. J Exp Med. 1998;188(1):119-131. (Pubitemid 28328611)