Cutting edge: Viral infection breaks nk cell tolerance to "missing self"

Journal of Immunology

Volumn 181, Issue 11, 2009, Pages 7453-7457

  Sun, Joseph C ^a   Lanier, Lewis L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 MICROGLOBULIN; GAMMA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CHIMERA; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOMEGALOVIRUS INFECTION; DISEASE MODEL; HEMATOPOIETIC CELL; HOST CELL; IMMUNOLOGICAL TOLERANCE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; VIRUS INFECTION; WILD TYPE;

EID: 71849094370     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.181.11.7453     Document Type: Article

References (25)

1. Ljunggren, H. G., and K. Karre. 1990. In search of the 'missing self': MHC molecules and NK cell recognition. Immunol. Today 11: 237-244.
2. Bix, M., N. S. Liao, M. Zijlstra, J. Loring, R. Jaenisch, and D. Raulet. 1991. Rejection of class I MHC-deficient haemopoietic cells by irradiated MHC-matched mice. Nature 349: 329-331. (Pubitemid 21912075)
3. - bone marrow in chimeric mice. Proc. Natl. Acad. Sci. USA 88: 10332-10336.
4. Liao, N. S., M. Bix, M. Zijlstra, R. Jaenisch, and D. Raulet. 1991. MHC class I deficiency: susceptibility to natural killer (NK) cells and impaired NK activity. Science 253: 199-202.
5. Ljunggren, H. G., L. Van Kaer, H. L. Ploegh, and S. Tonegawa. 1994. Altered natural killer cell repertoire in Tap-1 mutant mice. Proc. Natl. Acad. Sci. USA 91: 6520-6524. (Pubitemid 24200693)
6. Grigoriadou, K., C. Menard, B. Perarnau, and F. A. Lemonnier. 1999. MHC class Ia molecules alone control NK-mediated bone marrow graft rejection. Eur. J. Immunol. 29: 3683-3690. (Pubitemid 29527817)
7. 2-Microglobulin-deficient NK cells show increased sensitivity to MHC class I-mediated inhibition, but self tolerance does not depend upon target cell expression of H-2Kb and Db heavy chains. Eur. J. Immunol. 28: 370-378.
8. Fernandez, N. C., E. Treiner, R. E. Vance, A. M. Jamieson, S. Lemieux, and D. H. Raulet. 2005. A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC molecules. Blood 105: 4416-4423.
9. Kim, S., J. Poursine-Laurent, S. M. Truscott, L. Lybarger, Y. J. Song, L. Yang, A. R. French, J. B. Sunwoo, S. Lemieux, T. H. Hansen, and W. M. Yokoyama. 2005. Licensing of natural killer cells by host major histocompatibility complex class I molecules. Nature 436: 709-713. (Pubitemid 41117274)
10. + cells as effectors of IFN-γ dependent immunity to Toxoplasma gondii in MHC class I-deficient mice. J. Exp. Med. 178: 1465-1472.
11. Polic, B., S. Jonjic, I. Pavic, I. Crnkovic, I. Zorica, H. Hengel, P. Lucin, and U. H. Koszinowski. 1996. Lack of MHC class I complex expression has no effect on spread and control of cytomegalovirus infection in vivo. J. Gen. Virol. 77: 217-225. (Pubitemid 26044140)
12. 2-microglobulin-deficient mice. J. Immunol. 154: 780-789.
13. Sun, J. C., S. M. Lehar, and M. J. Bevan. 2006. Augmented IL-7 signaling during viral infection drives greater expansion of effector T cells but does not enhance memory. J. Immunol. 177: 4458-4463.
14. Sun, J. C., and L. L. Lanier. 2008. Tolerance of NK cells encountering their viral ligand during development. J. Exp. Med. 205: 1819-1828.
15. Yokoyama, W. M., and S. Kim. 2006. Licensing of natural killer cells by self-major histocompatibility complex class I. Immunol. Rev. 214: 143-154. (Pubitemid 44707908)
16. Corral, L., T. Hanke, R. E. Vance, D. Cado, and D. H. Raulet. 2000. NK cell expression of the killer cell lectin-like receptor G1 (KLRG1), the mouse homolog of MAFA, is modulated by MHC class I molecules. Eur. J. Immunol. 30: 920-930. (Pubitemid 30216267)
17. Robbins, S. H., M. S. Tessmer, L. Van Kaer, and L. Brossay. 2005. Direct effects of T-bet andMHCclass I expression, but not STAT1, on peripheralNKcell maturation. Eur. J. Immunol. 35: 757-765.
18. - mice. J. Immunol. 159: 5219-5225.
19. Held, W., J. R. Dorfman, M. F. Wu, and D. H. Raulet. 1996. Major histocompatibility complex class I-dependent skewing of the natural killer cell Ly49 receptor repertoire. Eur. J. Immunol. 26: 2286-2292. (Pubitemid 26340925)
20. Salcedo, M., A. D. Diehl, M. Y. Olsson-Alheim, J. Sundback, L. Van Kaer, K. Karre, and H. G. Ljunggren. 1997. Altered expression of Ly49 inhibitory receptors on natural killer cells from MHC class I-deficient mice. J. Immunol. 158: 3174-3180. (Pubitemid 127484031)
21. Arase, H., E. S. Mocarski, A. E. Campbell, A. B. Hill, and L. L. Lanier. 2002. Direct recognition of cytomegalovirus by activating and inhibitory NK cell receptors. Science 296: 1323-1326. (Pubitemid 34522789)
22. Smith, H. R., J. W. Heusel, I. K. Mehta, S. Kim, B. G. Dorner, O. V. Naidenko, K. Iizuka, H. Furukawa, D. L. Beckman, J. T. Pingel, et al. 2002. Recognition of a virus-encoded ligand by a natural killer cell activation receptor. Proc. Natl. Acad. Sci. USA 99: 8826-8831. (Pubitemid 34693643)
23. Biron, C. A., K. B. Nguyen, G. C. Pien, L. P. Cousens, and T. P. Salazar-Mather. 1999. Natural killer cells in antiviral defense: function and regulation by innate cytokines. Annu. Rev. Immunol. 17: 189-220.
24. Wu, M. F., and D. H. Raulet. 1997. Class I-deficient hemopoietic cells and nonhemopoietic cells dominantly induce unresponsiveness of natural killer cells to class Ideficient bone marrow cell grafts. J. Immunol. 158: 1628-1633.
25. Johansson, M. H., C. Bieberich, G. Jay, K. Karre, and P. Hoglund. 1997. Natural killer cell tolerance in mice with mosaic expression of major histocompatibility complex class I transgene. J. Exp. Med. 186: 353-364.