메뉴 건너뛰기




Volumn 26, Issue 1, 2011, Pages 29-40

Biomarkers of acute kidney injury in children: Discovery, evaluation, and clinical application

Author keywords

Acute renal failure; Children; Chronic kidney disease; Diagnostic test; Genomics; Proteomics

Indexed keywords

BIOLOGICAL MARKER; FATTY ACID BINDING PROTEIN; INTERLEUKIN 18; KIDNEY INJURY MOLECULE 1; LIVER TYPE FATTY ACID BINDING PROTEIN; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; UNCLASSIFIED DRUG;

EID: 79953019722     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00467-010-1576-0     Document Type: Review
Times cited : (79)

References (75)
  • 1
    • 0035100888 scopus 로고    scopus 로고
    • Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework
    • Biomarkers Definitions Working Group
    • Biomarkers Definitions Working Group (2001) Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clin Pharmacol Ther 69:89-95
    • (2001) Clin Pharmacol Ther , vol.69 , pp. 89-95
  • 6
  • 7
    • 30944437447 scopus 로고    scopus 로고
    • 3-5 year longitudinal follow-up of pediatric patients after acute renal failure
    • DOI 10.1038/sj.ki.5000032, PII 5000032
    • Askenazi DJ, Feig DI, Graham NM, Hui-Stickle S, Goldstein SL (2006) 3-5 year longitudinal follow-up of pediatric patients after acute renal failure. Kidney Int 69:184-189 (Pubitemid 43117757)
    • (2006) Kidney International , vol.69 , Issue.1 , pp. 184-189
    • Askenazi, D.J.1    Feig, D.I.2    Graham, N.M.3    Hui-Stickle, S.4    Goldstein, S.L.5
  • 8
    • 42549102138 scopus 로고    scopus 로고
    • Urinary biomarkers for acute kidney injury: Perspectives on translation
    • Coca SG, Parikh CR (2008) Urinary biomarkers for acute kidney injury: perspectives on translation. Clin J Am Soc Nephrol 3:481-490
    • (2008) Clin J Am Soc Nephrol , vol.3 , pp. 481-490
    • Coca, S.G.1    Parikh, C.R.2
  • 9
    • 33645513979 scopus 로고    scopus 로고
    • Biomarker technology roundup: From discovery to clinical applications, a broad set of tools is required to translate from the lab to the clinic
    • Scaros O, Fisler R (2005) Biomarker technology roundup: from discovery to clinical applications, a broad set of tools is required to translate from the lab to the clinic. Biotechniques Suppl:30-32
    • (2005) Biotechniques Suppl , pp. 30-32
    • Scaros, O.1    Fisler, R.2
  • 11
    • 0036898579 scopus 로고    scopus 로고
    • Protein microarrays and proteomics
    • MacBeath G (2002) Protein microarrays and proteomics. Nat Genet 32(Suppl):526-532 (Pubitemid 35435157)
    • (2002) Nature Genetics , vol.32 , Issue.5 SUPPL. , pp. 526-532
    • MacBeath, G.1
  • 13
    • 0032694577 scopus 로고    scopus 로고
    • Metabonomics: Understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
    • Nicholson JK, Lindon JC, Holmes E (1999) 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica 29:1181-1189
    • (1999) Xenobiotica , vol.29 , pp. 1181-1189
    • Nicholson, J.K.1    Lindon, J.C.2    Holmes, E.3
  • 18
    • 56749169415 scopus 로고    scopus 로고
    • Neutrophil gelatinase-associated lipocalin-an emerging troponin for kidney injury
    • Devarajan P (2008) Neutrophil gelatinase-associated lipocalin-an emerging troponin for kidney injury. Nephrol Dial Transplant 23:3737-3743
    • (2008) Nephrol Dial Transplant , vol.23 , pp. 3737-3743
    • Devarajan, P.1
  • 19
    • 0027420678 scopus 로고
    • Structural and functional heterogeneity among peroxidase-negative granules in human neutrophils: Identification of a distinct gelatinase- containing granule subset by combined immunocytochemistry and subcellular fractionation
    • Kjeldsen L, Bainton DF, Sengelov H, Borregaard N (1993) Structural and functional heterogeneity among peroxidasenegative granules in human neutrophils: identification of a distinct gelatinase-containing granule subset by combined immunocytochemistry and subcellular fractionation. Blood 82:3183-3191 (Pubitemid 23334949)
    • (1993) Blood , vol.82 , Issue.10 , pp. 3183-3191
    • Kjeldsen, L.1    Bainton, D.F.2    Sengelov, H.3    Borregaard, N.4
  • 22
    • 4043163418 scopus 로고    scopus 로고
    • Neutrophil gelatinase-associated lipocalin: A novel early urinary biomarker for cisplatin nephrotoxicity
    • DOI 10.1159/000078452
    • Mishra J, Mori K, Ma Q, Kelly C, Barasch J, Devarajan P (2004) Neutrophil gelatinase-associated lipocalin: a novel early urinary biomarker for cisplatin nephrotoxicity. Am J Nephrol 24:307-315 (Pubitemid 39070114)
    • (2004) American Journal of Nephrology , vol.24 , Issue.3 , pp. 307-315
    • Mishra, J.1    Mori, K.2    Ma, Q.3    Kelly, C.4    Barasch, J.5    Devarajan, P.6
  • 25
    • 84882379678 scopus 로고    scopus 로고
    • Plasma neutrophil gelatinase-associated lipocalin predicts acute kidney injury, morbidity and mortality after pediatric cardiac surgery: A prospective uncontrolled cohort study
    • Dent CL, Ma Q, Dastrala S, Bennett M, Mitsnefes MM, Barasch J, Devarajan P (2007) Plasma neutrophil gelatinase-associated lipocalin predicts acute kidney injury, morbidity and mortality after pediatric cardiac surgery: a prospective uncontrolled cohort study. Crit Care 11:R127
    • (2007) Crit Care , vol.11
    • Dent, C.L.1    Ma, Q.2    Dastrala, S.3    Bennett, M.4    Mitsnefes, M.M.5    Barasch, J.6    Devarajan, P.7
  • 27
    • 70449637194 scopus 로고    scopus 로고
    • Accuracy of neutrophil gelatinase-associated lipocalin (NGAL) in diagnosis and prognosis in acute kidney injury: A systematic review and meta-analysis
    • Haase M, Bellomo R, Devarajan P, Schlattmann P, Haase-Fielitz A (2009) Accuracy of neutrophil gelatinase-associated lipocalin (NGAL) in diagnosis and prognosis in acute kidney injury: a systematic review and meta-analysis. Am J Kidney Dis 54:1012-1024
    • (2009) Am J Kidney Dis , vol.54 , pp. 1012-1024
    • Haase, M.1    Bellomo, R.2    Devarajan, P.3    Schlattmann, P.4    Haase-Fielitz, A.5
  • 30
    • 45149086706 scopus 로고    scopus 로고
    • Progression From Acute Kidney Injury to Chronic Kidney Disease: A Pediatric Perspective
    • DOI 10.1053/j.ackd.2008.04.007, PII S1548559508000542
    • Goldstein SL, Devarajan P (2008) Progression from acute kidney injury to chronic kidney disease: a pediatric perspective. Adv Chronic Kidney Dis 15:278-283 (Pubitemid 351833144)
    • (2008) Advances in Chronic Kidney Disease , vol.15 , Issue.3 , pp. 278-283
    • Goldstein, S.L.1    Devarajan, P.2
  • 31
    • 38949157739 scopus 로고    scopus 로고
    • The Role of Interleukin-18 in Renal Injury
    • DOI 10.1016/j.jss.2007.03.037, PII S0022480407002053
    • Leslie JA, Meldrum KK (2008) The role of interleukin-18 in renal injury. J Surg Res 145:170-175 (Pubitemid 351221082)
    • (2008) Journal of Surgical Research , vol.145 , Issue.1 , pp. 170-175
    • Leslie, J.A.1    Meldrum, K.K.2
  • 35
    • 33644819168 scopus 로고    scopus 로고
    • Urine IL-18 is an early diagnostic marker for acute kidney injury and predicts mortality in the intensive care unit
    • DOI 10.1681/ASN.2005030236
    • Parikh CR, Abraham E, Ancukiewicz M, Edelstein CL (2005) Urine IL-18 is an early diagnostic marker for acute kidney injury and predicts mortality in the intensive care unit. J Am Soc Nephrol 16:3046-3052 (Pubitemid 44743502)
    • (2005) Journal of the American Society of Nephrology , vol.16 , Issue.10 , pp. 3046-3052
    • Parikh, C.R.1    Abraham, E.2    Ancukiewicz, M.3    Edelstein, C.L.4
  • 37
    • 50049134780 scopus 로고    scopus 로고
    • Urinary interleukin-18 does not predict acute kidney injury after adult cardiac surgery: A prospective observational cohort study
    • Haase M, Bellomo R, Story D, Davenport P, Haase-Fielitz A (2008) Urinary interleukin-18 does not predict acute kidney injury after adult cardiac surgery: a prospective observational cohort study. Crit Care 12:R96
    • (2008) Crit Care , vol.12
    • Haase, M.1    Bellomo, R.2    Story, D.3    Davenport, P.4    Haase-Fielitz, A.5
  • 39
    • 0032512724 scopus 로고    scopus 로고
    • Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cells after injury
    • DOI 10.1074/jbc.273.7.4135
    • Ichimura T, Bonventre JV, Bailly V, Wei H, Hession CA, Cate RL, Sanicola M (1998) Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cells after injury. J Biol Chem 273:4135-4142 (Pubitemid 28103282)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.7 , pp. 4135-4142
    • Ichimura, T.1    Bonventre, J.V.2    Bailly, V.3    Wei, H.4    Hession, C.A.5    Cate, R.L.6    Sanicola, M.7
  • 40
    • 0036314217 scopus 로고    scopus 로고
    • Kidney Injury Molecule-1 (KIM-1): A novel biomarker for human renal proximal tubule injury
    • DOI 10.1046/j.1523-1755.2002.00433.x
    • Han WK, Bailly V, Abichandani R, Thadhani R, Bonventre JV (2002) Kidney Injury Molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury. Kidney Int 62:237-244 (Pubitemid 34754067)
    • (2002) Kidney International , vol.62 , Issue.1 , pp. 237-244
    • Han, W.K.1    Bailly, V.2    Abichandani, R.3    Thadhani, R.4    Bonventre, J.V.5
  • 41
    • 0037131165 scopus 로고    scopus 로고
    • Shedding of kidney injury molecule-1, a putative adhesion protein involved in renal regeneration
    • DOI 10.1074/jbc.M200562200
    • Bailly V, Zhang Z, Meier W, Cate R, Sanicola M, Bonventre JV (2002) Shedding of kidney injury molecule-1, a putative adhesion protein involved in renal regeneration. J Biol Chem 277:39739-39748 (Pubitemid 35190957)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.42 , pp. 39739-39748
    • Bailly, V.1    Zhang, Z.2    Meier, W.3    Cate, R.4    Sanicola, M.5    Bonventre, J.V.6
  • 48
    • 36949014801 scopus 로고    scopus 로고
    • Comparison of kidney injury molecule-1 and other nephrotoxicity biomarkers in urine and kidney following acute exposure to gentamicin, mercury, and chromium
    • DOI 10.1093/toxsci/kfm260
    • Zhou Y, Vaidya VS, Brown RP, Zhang J, Rosenzweig BA, Thompson KL, Miller TJ, Bonventre JV, Goering PL (2008) Comparison of kidney injury molecule-1 and other nephrotoxicity biomarkers in urine and kidney following acute exposure to gentamicin, mercury, and chromium. Toxicol Sci 101:159-170 (Pubitemid 350239020)
    • (2008) Toxicological Sciences , vol.101 , Issue.1 , pp. 159-170
    • Zhou, Y.1    Vaidya, V.S.2    Brown, R.P.3    Zhang, J.4    Rosenzweig, B.A.5    Thompson, K.L.6    Miller, T.J.7    Bonventre, J.V.8    Goering, P.I.9
  • 49
    • 67649639427 scopus 로고    scopus 로고
    • Expression of kidney injury molecule-1 (Kim-1) in relation to necrosis and apoptosis during the early stages of Cd-induced proximal tubule injury
    • Prozialeck WC, Edwards JR, Lamar PC, Liu J, Vaidya VS, Bonventre JV (2009) Expression of kidney injury molecule-1 (Kim-1) in relation to necrosis and apoptosis during the early stages of Cd-induced proximal tubule injury. Toxicol Appl Pharmacol 238:306-314
    • (2009) Toxicol Appl Pharmacol , vol.238 , pp. 306-314
    • Prozialeck, W.C.1    Edwards, J.R.2    Lamar, P.C.3    Liu, J.4    Vaidya, V.S.5    Bonventre, J.V.6
  • 56
    • 44449094660 scopus 로고    scopus 로고
    • Renal L-type fatty acid-binding protein mediates the bezafibrate reduction of cisplatin-induced acute kidney injury
    • DOI 10.1038/ki.2008.106, PII KI2008106
    • Negishi K, Noiri E, Maeda R, Portilla D, Sugaya T, Fujita T (2008) Renal L-type fatty acid-binding protein mediates the bezafibrate reduction of cisplatin-induced acute kidney injury. Kidney Int 73:1374-1384 (Pubitemid 351770480)
    • (2008) Kidney International , vol.73 , Issue.12 , pp. 1374-1384
    • Negishi, K.1    Noiri, E.2    Maeda, R.3    Portilla, D.4    Sugaya, T.5    Fujita, T.6
  • 58
    • 33749985757 scopus 로고    scopus 로고
    • Urinary fatty acid binding protein in renal disease
    • DOI 10.1016/j.cca.2006.05.038, PII S0009898106003421
    • Kamijo-Ikemori A, Sugaya T, Kimura K (2006) Urinary fatty acid binding protein in renal disease. Clin Chim Acta 374:1-7 (Pubitemid 44572240)
    • (2006) Clinica Chimica Acta , vol.374 , Issue.1-2 , pp. 1-7
    • Kamijo-Ikemori, A.1    Sugaya, T.2    Kimura, K.3
  • 59
    • 65349126356 scopus 로고    scopus 로고
    • Monitoring of urinary L-type fatty acid-binding protein predicts histological severity of acute kidney injury
    • Negishi K, Noiri E, Doi K, Maeda-Mamiya R, Sugaya T, Portilla D, Fujita T (2009) Monitoring of urinary L-type fatty acid-binding protein predicts histological severity of acute kidney injury. Am J Pathol 174:1154-1159
    • (2009) Am J Pathol , vol.174 , pp. 1154-1159
    • Negishi, K.1    Noiri, E.2    Doi, K.3    Maeda-Mamiya, R.4    Sugaya, T.5    Portilla, D.6    Fujita, T.7
  • 60
    • 32844455180 scopus 로고    scopus 로고
    • Urinary excretion of liver-type fatty acid-binding protein in contrast medium-induced nephropathy
    • DOI 10.1053/j.ajkd.2005.11.006, PII S0272638605016835
    • Nakamura T, Sugaya T, Node K, Ueda Y, Koide H (2006) Urinary excretion of liver-type fatty acid-binding protein in contrast medium-induced nephropathy. Am J Kidney Dis 47:439-444 (Pubitemid 43255177)
    • (2006) American Journal of Kidney Diseases , vol.47 , Issue.3 , pp. 439-444
    • Nakamura, T.1    Sugaya, T.2    Node, K.3    Ueda, Y.4    Koide, H.5
  • 62
    • 38749115028 scopus 로고    scopus 로고
    • Liver fatty acid-binding protein as a biomarker of acute kidney injury after cardiac surgery
    • DOI 10.1038/sj.ki.5002721, PII 5002721
    • Portilla D, Dent C, Sugaya T, Nagothu KK, Kundi I, Moore P, Noiri E, Devarajan P (2008) Liver fatty acid-binding protein as a biomarker of acute kidney injury after cardiac surgery. Kidney Int 73:465-472 (Pubitemid 351186293)
    • (2008) Kidney International , vol.73 , Issue.4 , pp. 465-472
    • Portilla, D.1    Dent, C.2    Sugaya, T.3    Nagothu, K.K.4    Kundi, I.5    Moore, P.6    Noiri, E.7    Devarajan, P.8
  • 63
    • 67651236801 scopus 로고    scopus 로고
    • Serum interleukin-6 and interleukin- 8 are early biomarkers of acute kidney injury and predict prolonged mechanical ventilation in children undergoing cardiac surgery: A case-control study
    • Liu KD, Altmann C, Smits G, Krawczeski CD, Edelstein CL, Devarajan P, Faubel S (2009) Serum interleukin-6 and interleukin- 8 are early biomarkers of acute kidney injury and predict prolonged mechanical ventilation in children undergoing cardiac surgery: a case-control study. Crit Care 13:R104
    • (2009) Crit Care , vol.13
    • Liu, K.D.1    Altmann, C.2    Smits, G.3    Krawczeski, C.D.4    Edelstein, C.L.5    Devarajan, P.6    Faubel, S.7
  • 65
    • 73449101815 scopus 로고    scopus 로고
    • Measurement and estimation of GFR in children and adolescents
    • Schwartz GJ, Work DF (2009) Measurement and estimation of GFR in children and adolescents. Clin J Am Soc Nephrol 4:1832-1843
    • (2009) Clin J Am Soc Nephrol , vol.4 , pp. 1832-1843
    • Schwartz, G.J.1    Work, D.F.2
  • 67
    • 70449644753 scopus 로고    scopus 로고
    • Serum cystatin C for prediction of dialysis requirement or death in acute kidney injury: A comparative study
    • Perianayagam MC, Seabra VF, Tighiouart H, Liangos O, Jaber BL (2009) Serum cystatin C for prediction of dialysis requirement or death in acute kidney injury: a comparative study. Am J Kidney Dis 54:1025-1033
    • (2009) Am J Kidney Dis , vol.54 , pp. 1025-1033
    • Perianayagam, M.C.1    Seabra, V.F.2    Tighiouart, H.3    Liangos, O.4    Jaber, B.L.5
  • 69
    • 41649097463 scopus 로고    scopus 로고
    • Serum neutrophil gelatinase-associated lipocalin (NGAL) as a marker of acute kidney injury in critically ill children with septic shock
    • DOI 10.1097/CCM.0b013e318169245a, PII 0000324620080400000036
    • Wheeler DS, Devarajan P, Ma Q, Harmon K, Monaco M, Cvijanovich N, Wong HR (2008) Serum neutrophil gelatinaseassociated lipocalin (NGAL) as a marker of acute kidney injury in critically ill children with septic shock. Crit Care Med 36:1297-1303 (Pubitemid 351482681)
    • (2008) Critical Care Medicine , vol.36 , Issue.4 , pp. 1297-1303
    • Wheeler, D.S.1    Devarajan, P.2    Ma, Q.3    Harmon, K.4    Monaco, M.5    Cvijanovich, N.6    Wong, H.R.7
  • 70
    • 34547863206 scopus 로고    scopus 로고
    • Urine neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in critically ill children: A prospective cohort study
    • Zappitelli M, Washburn KK, Arikan AA, Loftis L, Ma Q, Devarajan P, Parikh CR, Goldstein SL (2007) Urine neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in critically ill children: a prospective cohort study. Crit Care 11:R84
    • (2007) Crit Care , vol.11
    • Zappitelli, M.1    Washburn, K.K.2    Arikan, A.A.3    Loftis, L.4    Ma, Q.5    Devarajan, P.6    Parikh, C.R.7    Goldstein, S.L.8
  • 71
    • 33646689041 scopus 로고    scopus 로고
    • Kidney NGAL is a novel early marker of acute injury following transplantation
    • DOI 10.1007/s00467-006-0055-0
    • Mishra J, Ma Q, Kelly C, Mitsnefes M, Mori K, Barasch J, Devarajan P (2006) Kidney NGAL is a novel early marker of acute injury following transplantation. Pediatr Nephrol 21:856-863 (Pubitemid 43740956)
    • (2006) Pediatric Nephrology , vol.21 , Issue.6 , pp. 856-863
    • Mishra, J.1    Ma, Q.2    Kelly, C.3    Mitsnefes, M.4    Mori, K.5    Barasch, J.6    Devarajan, P.7
  • 73
    • 49749083047 scopus 로고    scopus 로고
    • Kidney injury molecule-1 expression identifies proximal tubular injury in urate nephropathy
    • Nepal M, Bock GH, Sehic AM, Schultz MF, Zhang PL (2008) Kidney injury molecule-1 expression identifies proximal tubular injury in urate nephropathy. Ann Clin Lab Sci 38:210-214
    • (2008) Ann Clin Lab Sci , vol.38 , pp. 210-214
    • Nepal, M.1    Bock, G.H.2    Sehic, A.M.3    Schultz, M.F.4    Zhang, P.L.5
  • 74
    • 46949085898 scopus 로고    scopus 로고
    • Urinary aprotinin as a predictor of acute kidney injury after cardiac surgery in children receiving aprotinin therapy
    • Nguyen MT, Dent CL, Ross GF, Harris N, Manning PB, Mitsnefes MM, Devarajan P (2008) Urinary aprotinin as a predictor of acute kidney injury after cardiac surgery in children receiving aprotinin therapy. Pediatr Nephrol 23:1317-1326
    • (2008) Pediatr Nephrol , vol.23 , pp. 1317-1326
    • Nguyen, M.T.1    Dent, C.L.2    Ross, G.F.3    Harris, N.4    Manning, P.B.5    Mitsnefes, M.M.6    Devarajan, P.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.