Biofabrication of a three-dimensional liver micro-organ as an in vitro drug metabolism model

Biofabrication

Volumn 2, Issue 4, 2010, Pages

  Chang, Robert ^a   Emami, Kamal ^b   Wu, Honglu ^b   Sun, Wei ^a  

^a Drexel University   (United States)

^b NASA JOHNSON SPACE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOACTIVE MATRICES; BIOFABRICATION; BIOLOGICAL INSIGHT; BIOPRINTING; CELL MATRIX INTERACTIONS; COMPLEX WELL; DESIGN PATTERNS; DRUG METABOLISMS; DRUG SCREENING; ENGINEERING DESIGN PROCESS; HIGH FIDELITY; HIGH THROUGHPUT; IN-VITRO; IN-VIVO; LAYERED SOLIDS; LENGTH SCALE; LIVER CELLS; LIVER TISSUE; MATRIX; METABOLIC FUNCTION; MICRO PATTERNING; MICRO-FABRICATION TECHNIQUES; MICRO-FLUIDIC DEVICES; MICRO-SCALES; MICROANALYTICAL DEVICES; MICROENVIRONMENTS; MICROFABRICATED SYSTEMS; PHARMACOKINETIC PROFILES; PLANETARY ENVIRONMENTS; PROCESS DEVELOPMENT; THREE-DIMENSIONAL ARCHITECTURE; TISSUE CONSTRUCTS;

BIOMIMETICS; CELL CULTURE; CELLS; LIVER; METABOLISM; MICROANALYSIS; MICROFABRICATION; MICROFLUIDICS; MODELS; NASA; TISSUE; TISSUE ENGINEERING;

THREE DIMENSIONAL;

DRUG; TISSUE SCAFFOLD;

ARTICLE; BIOLOGICAL MODEL; CELL STRAIN HEPG2; CULTURE TECHNIQUE; CYTOLOGY; DRUG EFFECT; DRUG SCREENING; EQUIPMENT DESIGN; HUMAN; INSTRUMENTATION; LIVER CELL; METABOLISM; METHODOLOGY; MICROFLUIDIC ANALYSIS; TISSUE ENGINEERING;

CELL CULTURE TECHNIQUES; DRUG EVALUATION, PRECLINICAL; EQUIPMENT DESIGN; HEP G2 CELLS; HEPATOCYTES; HUMANS; MICROFLUIDIC ANALYTICAL TECHNIQUES; MODELS, BIOLOGICAL; PHARMACEUTICAL PREPARATIONS; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 79953002875     PISSN: 17585082     EISSN: 17585090     Source Type: Journal    
DOI: 10.1088/1758-5082/2/4/045004     Document Type: Article

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