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Volumn 11, Issue 3, 2011, Pages 433-442

Predictive markers and driving factors behind Richter syndrome development

Author keywords

B cell receptor; CD38; chronic lymphocytic leukemia; del13q14; diffuse large B cell lymphoma; genetic lesions; IGHV genes; prognostic factors; Richter syndrome

Indexed keywords

CD38 ANTIGEN; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN HEAVY CHAIN VARIABLE REGION[4-39]; UNCLASSIFIED DRUG;

EID: 79952963276     PISSN: 14737140     EISSN: 17448328     Source Type: Journal    
DOI: 10.1586/era.10.237     Document Type: Review
Times cited : (14)

References (75)
  • 1
    • 0000421361 scopus 로고
    • Generalized reticular cell sarcoma of lymph nodes associated with lymphatic leukaemia
    • Richter MN. Generalized reticular cell sarcoma of lymph nodes associated with lymphatic leukaemia. Am. J. Pathol. 4(4), 285-292 (1928)
    • (1928) Am. J. Pathol. , vol.4 , Issue.4 , pp. 285-292
    • Richter, M.N.1
  • 2
    • 45149100665 scopus 로고    scopus 로고
    • International Workshop on Chronic Lymphocytic Leukemia. Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: A report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute Working Group 1996 guidelines
    • Hallek M, Cheson BD, Catovsky D, et al. International Workshop on Chronic Lymphocytic Leukemia. Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute Working Group 1996 guidelines. Blood 111(12), 5446-5456 (2008)
    • (2008) Blood , vol.111 , Issue.12 , pp. 5446-5456
    • Hallek, M.1    Cheson, B.D.2    Catovsky, D.3
  • 4
    • 12344301903 scopus 로고    scopus 로고
    • Richter syndrome: Biology, incidence, and therapeutic strategies
    • DOI 10.1002/cncr.20773
    • Tsimberidou A-M, Keating MJ. Richter syndrome. Biology, incidence, and therapeutic strategies. Cancer 103(2), 216-228 (2005) (Pubitemid 40129279)
    • (2005) Cancer , vol.103 , Issue.2 , pp. 216-228
    • Tsimberidou, A.-M.1    Keating, M.J.2
  • 6
    • 0027488805 scopus 로고
    • Common clonal origin of chronic lymphocytic leukemia and high-grade lymphoma of Richter's syndrome
    • Cherepakhin V, Baird SM, Meisenholder GW, Kipps TJ. Common clonal origin of chronic lymphocytic leukemia and high grade lymphoma of Richter's syndrome. Blood 82(10), 3141-3147 (1993) (Pubitemid 23334942)
    • (1993) Blood , vol.82 , Issue.10 , pp. 3141-3147
    • Cherepakhin, V.1    Baird, S.M.2    Meisenholder, G.W.3    Kipps, T.J.4
  • 7
    • 0028031704 scopus 로고
    • Molecular genetic demonstration of the diverse evolution of Richter's syndrome (chronic lymphocytic leukemia and subsequent large cell lymphoma)
    • Matolcsy A, Inghirami G, Knowles DM. Molecular genetic demonstration of the diverse evolution of Richter's syndrome (chronic lymphocytic leukemia and subsequent large cell lymphoma). Blood 83(5), 1363-1372 (1994) (Pubitemid 24062860)
    • (1994) Blood , vol.83 , Issue.5 , pp. 1363-1372
    • Matolcsy, A.1    Inghirami, G.2    Knowles, D.M.3
  • 8
    • 0033816305 scopus 로고    scopus 로고
    • Analysis of the immunoglobulin heavy chain gene of secondary diffuse large B-cell lymphoma that subsequently developed in four cases with B-cell chronic lymphocytic leukemia or lymphoplasmacytoid lymphoma (Richter syndrome)
    • Nakamura N, Kuze T, Hashimoto Y, et al. Analysis of the immunoglobulin heavy chain gene of secondary diffuse large B-cell lymphoma that subsequently developed in four cases with B-cell chronic lymphocytic leukemia or lymphoplasmacytoid lymphoma (Richter syndrome). Pathol. Int. 50(8), 636-643 (2000)
    • (2000) Pathol. Int. , vol.50 , Issue.8 , pp. 636-643
    • Nakamura, N.1    Kuze, T.2    Hashimoto, Y.3
  • 9
    • 1242329870 scopus 로고    scopus 로고
    • H genes and pathogenesis of diffuse large B-cell lymphoma in Richter's syndrome
    • DOI 10.1038/sj.leu.2403249
    • Timár B, Fülöp Z, Csernus B, et al. Relationship between the mutational status of VH genes and pathogenesis of diffuse large B-cell lymphoma in Richter's syndrome. Leukemia 18(2), 326-330 (2004) (Pubitemid 38240049)
    • (2004) Leukemia , vol.18 , Issue.2 , pp. 326-330
    • Timar, B.1    Fulop, Z.2    Csernus, B.3    Angster, C.4    Bognar, A.5    Szepesi, A.6    Kopper, L.7    Matolcsy, A.8
  • 16
    • 0017883241 scopus 로고
    • Diffuse histiocytic lymphoma complicating chronic lymphocytic leukemia
    • Armitage JO, Dick FR, Corder MP. Diffuse histiocytic lymphoma complicating chronic lymphocytic leukemia. Cancer 41(2), 422-427 (1978) (Pubitemid 8289254)
    • (1978) Cancer , vol.41 , Issue.2 , pp. 422-427
    • Armitage, J.O.1    Dick, F.R.2    Corder, M.P.3
  • 17
    • 0028947258 scopus 로고
    • Localized gastric non-Hodgkin's lymphoma of high-grade malignancy in patients with pre-existing chronic lymphocytic leukemia or immunocytoma
    • Ott MM, Ott G, Roblick U, et al. Localized gastric non-Hodgkin's lymphoma of high-grade malignancy in patients with pre-existing chronic lymphocytic leukemia or immunocytoma. Leukemia 9(4), 609-614 (1995)
    • (1995) Leukemia , vol.9 , Issue.4 , pp. 609-614
    • Ott, M.M.1    Ott, G.2    Roblick, U.3
  • 20
    • 48749112908 scopus 로고    scopus 로고
    • Richter syndrome: A review of clinical, ocular, neurological and other manifestations
    • Omoti CE, Omoti AE. Richter syndrome: a review of clinical, ocular, neurological and other manifestations. Br. J. Haematol. 142(5), 709-716 (2008)
    • (2008) Br. J. Haematol. , vol.142 , Issue.5 , pp. 709-716
    • Omoti, C.E.1    Omoti, A.E.2
  • 22
    • 0029044879 scopus 로고
    • De novo CD5-positive and Richter's syndrome-associated diffuse large B cell lymphomas are genotypically distinct
    • Matolcsy A, Chadburn A, Knowles DM. De novo CD5-positive and Richter's syndrome-associated diffuse large B cell lymphomas are genotypically distinct. Am. J. Pathol. 147(1), 207-216 (1995)
    • (1995) Am. J. Pathol. , vol.147 , Issue.1 , pp. 207-216
    • Matolcsy, A.1    Chadburn, A.2    Knowles, D.M.3
  • 25
    • 79952961237 scopus 로고    scopus 로고
    • The genetics of Richter syndrome identifies disease heterogeneity and is an independent predictor of survival post transformation
    • Barcelona, Spain, 10-13 June
    • Rossi D, Spina V, Deambrogi C, et al. The genetics of Richter syndrome identifies disease heterogeneity and is an independent predictor of survival post transformation. Presented at: 15th Congress of the European Hematology Association. Barcelona, Spain, 10-13 June 2010
    • (2010) 15th Congress of the European Hematology Association
    • Rossi, D.1    Spina, V.2    Deambrogi, C.3
  • 26
    • 38049130176 scopus 로고    scopus 로고
    • Prognostic assessment of BCL2-938C>A polymorphism in chronic lymphocytic leukemia
    • Rossi D, Rasi S, Capello D, Gaidano G. Prognostic assessment of BCL2-938C>A polymorphism in chronic lymphocytic leukemia. Blood 111(1), 466-468 (2008)
    • (2008) Blood , vol.111 , Issue.1 , pp. 466-468
    • Rossi, D.1    Rasi, S.2    Capello, D.3    Gaidano, G.4
  • 27
    • 54349128375 scopus 로고    scopus 로고
    • CD49d expression is an independent risk factor of progressive disease in early stage chronic lymphocytic leukemia
    • Rossi D, Zucchetto A, Rossi FM, et al. CD49d expression is an independent risk factor of progressive disease in early stage chronic lymphocytic leukemia. Haematologica 93(10), 1575-1579 (2008)
    • (2008) Haematologica , vol.93 , Issue.10 , pp. 1575-1579
    • Rossi, D.1    Zucchetto, A.2    Rossi, F.M.3
  • 28
    • 67650393955 scopus 로고    scopus 로고
    • Stereotyped B-cell receptor is an independent risk factor of chronic lymphocytc leukemia transformation to Richter syndrome
    • Rossi D, Spina V, Cerri M, et al. Stereotyped B-cell receptor is an independent risk factor of chronic lymphocytc leukemia transformation to Richter syndrome. Clin. Cancer Res. 15(13), 4415-4422 (2009)
    • (2009) Clin. Cancer Res. , vol.15 , Issue.13 , pp. 4415-4422
    • Rossi, D.1    Spina, V.2    Cerri, M.3
  • 29
    • 67349211312 scopus 로고    scopus 로고
    • Telomere length is an independent predictor of survival, treatment requirement and Richter's syndrome transformation in chronic lymphocytic leukemia
    • Rossi D, Lobetti Bodoni C, Genuardi E, et al. Telomere length is an independent predictor of survival, treatment requirement and Richter's syndrome transformation in chronic lymphocytic leukemia. Leukemia 23(6), 1062-1072 (2009)
    • (2009) Leukemia , vol.23 , Issue.6 , pp. 1062-1072
    • Rossi, D.1    Lobetti Bodoni, C.2    Genuardi, E.3
  • 31
    • 20544444461 scopus 로고    scopus 로고
    • Evidence for distinct pathomechanisms in genetic subgroups of chronic lymphocytic leukemia revealed by quantitative expression analysis of cell cycle, activation, and apoptosis-associated genes
    • Kienle DL, Korz C, Hosch B, et al. Evidence for distinct pathomechanisms in genetic subgroups of chronic lymphocytic leukemia revealed by quantitative expression analysis of cell cycle, activation, and apoptosis-associated genes. J. Clin. Oncol. 23(16), 3780-3792 (2005)
    • (2005) J. Clin. Oncol. , vol.23 , Issue.16 , pp. 3780-3792
    • Kienle, D.L.1    Korz, C.2    Hosch, B.3
  • 32
    • 73649116987 scopus 로고    scopus 로고
    • The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia
    • Klein U, Lia M, Crespo M, et al. The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia. Cancer Cell 17(1), 28-40 (2010)
    • (2010) Cancer Cell , vol.17 , Issue.1 , pp. 28-40
    • Klein, U.1    Lia, M.2    Crespo, M.3
  • 33
    • 0036090299 scopus 로고    scopus 로고
    • Gastric marginal zone B-cell lymphomas of MALT type develop along 2 distinct pathogenetic pathways
    • DOI 10.1182/blood.V99.1.3
    • Starostik P, Patzner J, Greiner A, et al. Gastric marginal zone B-cell lymphomas of MALT type develop along 2 distinct pathogenetic pathways. Blood 99(1), 3-9 (2002) (Pubitemid 34532956)
    • (2002) Blood , vol.99 , Issue.1 , pp. 3-9
    • Starostik, P.1    Patzner, J.2    Greiner, A.3    Schwarz, S.4    Kalla, J.5    Ott, G.6    Muller-Hermelink, H.K.7
  • 34
    • 57449116575 scopus 로고    scopus 로고
    • 14q32 translocations and risk of Richter's transformation in chronic lymphocytic leukaemia
    • Deambrogi C, Cresta S, Cerri M, et al. 14q32 translocations and risk of Richter's transformation in chronic lymphocytic leukaemia. Br. J. Haematol. 144(1), 131-133 (2009)
    • (2009) Br. J. Haematol. , vol.144 , Issue.1 , pp. 131-133
    • Deambrogi, C.1    Cresta, S.2    Cerri, M.3
  • 36
    • 58549100059 scopus 로고    scopus 로고
    • Molecular and clinical features of chronic lymphocytic leukaemia with stereotyped B cell receptors: Results from an Italian multicenter study
    • Bomben R, Dal Bo M, Capello D, et al. Molecular and clinical features of chronic lymphocytic leukaemia with stereotyped B cell receptors: results from an Italian multicenter study. Br. J. Haematol. 144(4), 492-506 (2009)
    • (2009) Br. J. Haematol. , vol.144 , Issue.4 , pp. 492-506
    • Bomben, R.1    Dal Bo, M.2    Capello, D.3
  • 37
    • 73349090583 scopus 로고    scopus 로고
    • Extensive intraclonal diversification in a subgroup of chronic lymphocytic leukemia patients with stereotyped IGHV4-34 receptors: Implications for ongoing interactions with antigen
    • Sutton LA, Kostareli E, Hadzidimitriou A, et al. Extensive intraclonal diversification in a subgroup of chronic lymphocytic leukemia patients with stereotyped IGHV4-34 receptors: implications for ongoing interactions with antigen. Blood 114(20), 4460-4468 (2009)
    • (2009) Blood , vol.114 , Issue.20 , pp. 4460-4468
    • Sutton, L.A.1    Kostareli, E.2    Hadzidimitriou, A.3
  • 38
    • 74249107417 scopus 로고    scopus 로고
    • A different ontogenesis for chronic lymphocytic leukemia cases carrying stereotyped antigen receptors: Molecular and computational evidence
    • Darzentas N, Hadzidimitriou A, Murray F, et al. A different ontogenesis for chronic lymphocytic leukemia cases carrying stereotyped antigen receptors: molecular and computational evidence. Leukemia 24(1), 125-132 (2010)
    • (2010) Leukemia , vol.24 , Issue.1 , pp. 125-132
    • Darzentas, N.1    Hadzidimitriou, A.2    Murray, F.3
  • 39
    • 52449121246 scopus 로고    scopus 로고
    • Novel insights in chronic lymphocytic leukemia: Are we getting closer to understanding the pathogenesis of the disease?
    • Caligaris-Cappio F, Ghia P. Novel insights in chronic lymphocytic leukemia: are we getting closer to understanding the pathogenesis of the disease? J. Clin. Oncol. 26(27), 4497-4503 (2008)
    • (2008) J. Clin. Oncol. , vol.26 , Issue.27 , pp. 4497-4503
    • Caligaris-Cappio, F.1    Ghia, P.2
  • 40
    • 77952965028 scopus 로고    scopus 로고
    • Many chronic lymphocytic leukemia antibodies recognize apoptotic cells with exposed nonmuscle myosin heavy chain IIA: Implications for patient outcome and cell of origin
    • Chu CC, Catera R, Zhang L, et al. Many chronic lymphocytic leukemia antibodies recognize apoptotic cells with exposed nonmuscle myosin heavy chain IIA: implications for patient outcome and cell of origin. Blood 115(19), 3907-3915 (2010)
    • (2010) Blood , vol.115 , Issue.19 , pp. 3907-3915
    • Chu, C.C.1    Catera, R.2    Zhang, L.3
  • 41
    • 0035525731 scopus 로고    scopus 로고
    • Clinical significance of CD38 expression in chronic lymphocytic leukemia
    • Del Poeta G, Maurillo L, Venditti A, et al. Clinical significance of CD38 expression in chronic lymphocytic leukemia. Blood 98(9), 2633-2639 (2001)
    • (2001) Blood , vol.98 , Issue.9 , pp. 2633-2639
    • Del Poeta, G.1    Maurillo, L.2    Venditti, A.3
  • 42
    • 0035412375 scopus 로고    scopus 로고
    • CD38 expression as an important prognostic factor in B-cell chronic lymphocytic leukemia
    • Ibrahim S, Keating M, Do KA, et al. CD38 expression as an important prognostic factor in B-cell chronic lymphocytic leukemia. Blood 98(1), 181-186 (2001)
    • (2001) Blood , vol.98 , Issue.1 , pp. 181-186
    • Ibrahim, S.1    Keating, M.2    Do, K.A.3
  • 43
    • 1442331700 scopus 로고    scopus 로고
    • CD38 on B-cell chronic lymphocytic leukemia cells has higher expression in lymph nodes than in peripheral blood or bone marrow [4]
    • DOI 10.1182/blood-2003-10-3612
    • Jaksic O, Paro MM, Kardum Skelin I, Kusec R, Pejsa V, Jaksic B. CD38 on B-cell chronic lymphocytic leukemia cells has higher expression in lymph nodes than in peripheral blood or bone marrow. Blood 103(5), 1968-1969 (2004) (Pubitemid 38269003)
    • (2004) Blood , vol.103 , Issue.5 , pp. 1968-1969
    • Jaksic, O.1    Kardum Paro, M.M.2    Kardum Skelin, I.3    Kusec, R.4    Pejsa, V.5    Jaksic, B.6
  • 45
  • 46
    • 33747187494 scopus 로고    scopus 로고
    • In-tandem insight from basic science combined with clinical research: CD38 as both marker and key component of the pathogenetic network underlying chronic lymphocytic leukemia
    • DOI 10.1182/blood-2006-01-013003
    • Deaglio S, Vaisitti T, Aydin S, Ferrero E, Malavasi F. In-tandem insights from basic science combined with clinical research: CD38 as both marker and key component of the pathogenetic network underlying chronic lymphocytic leukemia. Blood 108(4), 1135-1144 (2006) (Pubitemid 44232007)
    • (2006) Blood , vol.108 , Issue.4 , pp. 1135-1144
    • Deaglio, S.1    Vaisitti, T.2    Aydin, S.3    Ferrero, E.4    Malavasi, F.5
  • 47
    • 46749145421 scopus 로고    scopus 로고
    • CD38 expression in chronic lymphocytic leukemia is regulated by the tumor microenvironment
    • Patten PE, Buggins AG, Richards J, et al. CD38 expression in chronic lymphocytic leukemia is regulated by the tumor microenvironment. Blood 111(10), 5173-5181 (2008)
    • (2008) Blood , vol.111 , Issue.10 , pp. 5173-5181
    • Patten, P.E.1    Buggins, A.G.2    Richards, J.3
  • 48
    • 0032547063 scopus 로고    scopus 로고
    • Molecular mechanism of human CD38 gene expression by retinoic acid. Identification of retinoic acid response element in the first intron
    • DOI 10.1074/jbc.273.25.15429
    • Kishimoto H, Hoshino S, Ohori M, et al. Molecular mechanisms of human CD38 gene expression by retinoic acid. Identification of retinoic acid response element in the first intron. J. Biol. Chem. 273(25), 15429-15434 (1998) (Pubitemid 28298149)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.25 , pp. 15429-15434
    • Kishimoto, H.1    Hoshino, S.-I.2    Ohori, M.3    Kontani, K.4    Nishina, H.5    Suzawa, M.6    Kato, S.7    Katada, T.8
  • 49
    • 0033039354 scopus 로고    scopus 로고
    • The human CD38 gene: Polymorphism, CpG island, and linkage to the CD157 (BST-1) gene
    • DOI 10.1007/s002510050654
    • Ferrero E, Saccucci F, Malavasi F. The human CD38 gene: polymorphism, CpG island, and linkage to the CD157 (BST-1) gene. Immunogenetics 49(7-8), 597-604 (1999) (Pubitemid 29278445)
    • (1999) Immunogenetics , vol.49 , Issue.7-8 , pp. 597-604
    • Ferrero, E.1    Saccucci, F.2    Malavasi, F.3
  • 50
    • 47049131482 scopus 로고    scopus 로고
    • CD38 gene polymorphism and chronic lymphocytic leukemia: A role in Richter syndrome?
    • Aydin S, Rossi D, Bergui L, et al. CD38 gene polymorphism and chronic lymphocytic leukemia: a role in Richter syndrome? Blood 111(12), 5646-5653 (2008)
    • (2008) Blood , vol.111 , Issue.12 , pp. 5646-5653
    • Aydin, S.1    Rossi, D.2    Bergui, L.3
  • 51
    • 78651276641 scopus 로고    scopus 로고
    • A variant of the LRP4 gene affects the risk of chronic lymphocytic leukaemia transformation to Richter syndrome
    • Rasi S, Spina V, Bruscaggin A, et al. A variant of the LRP4 gene affects the risk of chronic lymphocytic leukaemia transformation to Richter syndrome. Br. J. Haematol. 152(3), 284-294 (2011)
    • (2011) Br. J. Haematol. , vol.152 , Issue.3 , pp. 284-294
    • Rasi, S.1    Spina, V.2    Bruscaggin, A.3
  • 53
    • 77952096764 scopus 로고    scopus 로고
    • LRP4 mutations alter Wnt/b-catenin signaling and cause limb and kidney malformations in Cenani-Lenz syndrome
    • Li Y, Pawlik B, Elcioglu N, et al. LRP4 mutations alter Wnt/b-catenin signaling and cause limb and kidney malformations in Cenani-Lenz syndrome. Am. J. Hum. Genet. 86(5), 696-706 (2010)
    • (2010) Am. J. Hum. Genet. , vol.86 , Issue.5 , pp. 696-706
    • Li, Y.1    Pawlik, B.2    Elcioglu, N.3
  • 54
    • 0028564951 scopus 로고
    • Specific association of human telomerase activity with immortal cells and cancer
    • Kim NW, Piatyszek MA, Prowse KR, et al. Specific association of human telomerase activity with immortal cells and cancer. Science 266(5193), 2011-2015 (1994)
    • (1994) Science , vol.266 , Issue.5193 , pp. 2011-2015
    • Kim, N.W.1    Piatyszek, M.A.2    Prowse, K.R.3
  • 57
    • 0027422990 scopus 로고
    • P53 Mutations are associated with histologic transformation of follicular lymphoma
    • Lo Coco F, Gaidano G, Louie DC, Offit K, Chaganti RS, Dalla-Favera R. p53 mutations are associated with histologic transformation of follicular lymphoma. Blood 82(8), 2289-2295 (1993) (Pubitemid 23304250)
    • (1993) Blood , vol.82 , Issue.8 , pp. 2289-2295
    • Lo Coco, F.1    Gaidano, G.2    Louie, D.C.3    Offit, K.4    Chaganti, R.S.K.5    Dalla-Favera, R.6
  • 58
    • 23744514780 scopus 로고    scopus 로고
    • Higher-grade transformation of follicular lymphoma - A continuous enigma
    • DOI 10.1038/sj.leu.2403801
    • Lossos IS. Higher-grade transformation of follicular lymphoma -a continuous enigma. Leukemia 19(8), 1331-1333 (2005) (Pubitemid 41136323)
    • (2005) Leukemia , vol.19 , Issue.8 , pp. 1331-1333
    • Lossos, I.S.1
  • 62
    • 37549015263 scopus 로고    scopus 로고
    • Germinal centres: Role in B-cell physiology and malignancy
    • Klein U, Dalla-Favera R. Germinal centres: role in B-cell physiology and malignancy. Nat. Rev. Immunol. 8(1), 22-33 (2008)
    • (2008) Nat. Rev. Immunol. , vol.8 , Issue.1 , pp. 22-33
    • Klein, U.1    Dalla-Favera, R.2
  • 63
    • 37549068541 scopus 로고    scopus 로고
    • AID is required for germinal center-derived lymphomagenesis
    • Pasqualucci L, Bhagat G, Jankovic M, et al. AID is required for germinal center-derived lymphomagenesis. Nat. Genetics 40(1), 108-112 (2008)
    • (2008) Nat. Genetics , vol.40 , Issue.1 , pp. 108-112
    • Pasqualucci, L.1    Bhagat, G.2    Jankovic, M.3
  • 64
    • 33744503388 scopus 로고    scopus 로고
    • Richter's and prolymphocytic transformation of chronic lymphocytic leukemia are associated with high mRNA expression of activation-induced cytidine deaminase and aberrant somatic hypermutation
    • DOI 10.1038/sj.leu.2404183, PII 2404183
    • Reiniger L, Bödör C, Bognár A, et al. Richter's and prolymphocytic transformation of chronic lymphocytic leukemia are associated with high mRNA expression of activation-induced cytidine deaminase and aberrant somatic hypermutation. Leukemia 20(6), 1089-1095 (2006) (Pubitemid 43797302)
    • (2006) Leukemia , vol.20 , Issue.6 , pp. 1089-1095
    • Reiniger, L.1    Bodor, C.2    Bognar, A.3    Balogh, Z.4    Csomor, J.5    Szepesi, A.6    Kopper, L.7    Matolcsy, A.8
  • 65
    • 0021163746 scopus 로고
    • Cytogenetic studies in 77 patients with chronic lymphocytic leukemia: Correlations with clinical, immunologic, and phenotypic data
    • Han T, Sadamori N, Ozer H, et al. Cytogenetic studies in 77 patients with chronic lymphocytic leukemia: correlations with clinical, immunologic, and phenotypic data. J. Clin. Oncol. 2(10), 1121-1132 (1984) (Pubitemid 14022700)
    • (1984) Journal of Clinical Oncology , vol.2 , Issue.10 , pp. 1121-1132
    • Han, T.1    Sadamori, N.2    Ozer, H.3
  • 66
  • 67
    • 0029052763 scopus 로고
    • Trisomy 12 in Richter's transformation of chronic lymphocytic leukemia
    • Brynes RK, McCourty A, Sun NC, Koo CH. Trisomy 12 in Richter's transformation of chronic lymphocytic leukemia. Am. J. Clin. Pathol. 104(2), 199-203 (1995)
    • (1995) Am. J. Clin. Pathol. , vol.104 , Issue.2 , pp. 199-203
    • Brynes, R.K.1    McCourty, A.2    Sun, N.C.3    Koo, C.H.4
  • 68
    • 0034712745 scopus 로고    scopus 로고
    • Numeric chromosomal abnormalities in small lymphocytic and transformed large cell lymphomas detected by fluorescence in situ hybridization of fine-needle aspiration biopsies
    • Caraway NP, Du Y, Zhang H-Z, Hayes K, Glassman AB, Katz RL. Numeric chromosomal abnormalities in small lymphocytic and transformed large cell lymphomas detected by fluorescence in situ hybridization of fine-needle aspiration biopsies. Cancer 90(2), 126-132 (2000)
    • (2000) Cancer , vol.90 , Issue.2 , pp. 126-132
    • Caraway, N.P.1    Du, Y.2    Zhang, H.-Z.3    Hayes, K.4    Glassman, A.B.5    Katz, R.L.6
  • 70
    • 46749108058 scopus 로고    scopus 로고
    • Molecular diagnostics in chronic lymphocytic leukemia - Pathogenetic and clinical implications
    • DOI 10.1080/10428190701882955, PII 790629237
    • Zenz T, Mertens D, Döhner H, Stilgenbauer S. Molecular diagnostics in chronic lymphocytic leukemia -pathogenetic and clinical implications. Leuk. Lymphoma 49(5), 864-873 (2008) (Pubitemid 351942738)
    • (2008) Leukemia and Lymphoma , vol.49 , Issue.5 , pp. 864-873
    • Zenz, T.1    Mertens, D.2    Dohner, H.3    Stilgenbauer, S.4
  • 71
    • 77951010885 scopus 로고    scopus 로고
    • Aggressive lymphomas
    • Lenz G, Staudt LM. Aggressive lymphomas. N. Engl. J. Med. 362(15), 1417-1429 (2010)
    • (2010) N. Engl. J. Med. , vol.362 , Issue.15 , pp. 1417-1429
    • Lenz, G.1    Staudt, L.M.2
  • 73
    • 77953263477 scopus 로고    scopus 로고
    • Genomic profiling of Richter's syndrome: Recurrent lesions and differences with de novo diffuse large B-cell lymphomas
    • Scandurra M, Rossi D, Deambrogi C, et al. Genomic profiling of Richter's syndrome: recurrent lesions and differences with de novo diffuse large B-cell lymphomas. Hematol. Oncol. 28(2), 62-67 (2010)
    • (2010) Hematol. Oncol. , vol.28 , Issue.2 , pp. 62-67
    • Scandurra, M.1    Rossi, D.2    Deambrogi, C.3
  • 74
    • 0036245643 scopus 로고    scopus 로고
    • Large-cell transformation of chronic lymphocytic leukemia and follicular lymphoma during or soon after treatment with fludarabine - Rituximab-containing regimens: Natural history- or therapy-related complication?
    • DOI 10.1034/j.1600-0609.2002.01599.x
    • Cohen Y, Da?as N, Libster D, Amir G, Berrebi A, Polliack A. Large-cell transformation of chronic lymphocytic leukemia and follicular lymphoma during or soon after treatment with fludarabinerituximab containing regimens: natural history or related therapy complication. Eur. J. Hematol. 68(2), 80-83 (2002) (Pubitemid 34478271)
    • (2002) European Journal of Haematology , vol.68 , Issue.2 , pp. 80-83
    • Cohen, Y.1    Da'as, N.2    Libster, D.3    Amir, G.4    Berrebi, A.5    Polliack, A.6
  • 75
    • 13844255162 scopus 로고    scopus 로고
    • Richter's transformation of chronic lymphocytic leukemia: The possible role of fludarabine and the Epstein-Barr virus in its pathogenesis
    • DOI 10.1016/j.leukres.2004.09.008
    • Thornton PD, Bellas C, Santon A, et al. Richter's transformation of chronic lymphocytic leukemia. The possible role of fludarabine and the Epstein-Barr virus in its pathogenesis. Leukemia Res. 29(4), 389-395 (2005) (Pubitemid 40255812)
    • (2005) Leukemia Research , vol.29 , Issue.4 , pp. 389-395
    • Thornton, P.D.1    Bellas, C.2    Santon, A.3    Shah, G.4    Pocock, C.5    Wotherspoon, A.C.6    Matutes, E.7    Catovsky, D.8


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