IgVH mutational status and clonality analysis of Richter's transformation: Diffuse large B-cell lymphoma and hodgkin lymphoma in association with B-cell chronic lymphocytic leukemia (B-CLL) represent 2 different pathways of disease evolution

American Journal of Surgical Pathology

Volumn 31, Issue 10, 2007, Pages 1605-1614

  Mao, Zhengrong ^a   Quintanilla Martinez, Leticia ^b   Raffeld, Mark ^d   Richter, Manfred ^b   Krugmann, Jens ^e   Burek, Christof ^a   Hartmann, Elena ^a   Rudiger, Thomas ^a   Jaffe, Elaine S ^d   Müller Hermelink, Hans Konrad ^a   Ott, German ^a   Fend, Falko ^c   Rosenwald, Andreas ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d NATIONAL CANCER INSTITUTE   (United States)

^e UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

B cell chronic lymphocytic leukemia; Clonality analysis; Hodgkin lymphoma; IgH mutational analysis; Microdissection; Richter's transformation

Indexed keywords

ADULT; AGED; ARTICLE; B CELL LYMPHOMA; CELL ISOLATION; CELL STRUCTURE; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE COURSE; EPSTEIN BARR VIRUS; FEMALE; GENE MUTATION; HODGKIN DISEASE; HUMAN; HUMAN TISSUE; IMMUNOGLOBULIN HEAVY CHAIN GENE; IMMUNOPHENOTYPING; MALE; MICRODISSECTION; MOLECULAR CLONING; REED STERNBERG CELL; SEQUENCE ANALYSIS; TUMOR CELL; VIRUS INFECTION;

ADULT; AGED; AGED, 80 AND OVER; CELL TRANSFORMATION, NEOPLASTIC; CLONE CELLS; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; FEMALE; GENE REARRANGEMENT, B-LYMPHOCYTE; HODGKIN DISEASE; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN VARIABLE REGION; LASERS; LEUKEMIA, LYMPHOCYTIC, CHRONIC; LYMPHOMA, B-CELL; LYMPHOMA, LARGE-CELL, DIFFUSE; MALE; MICRODISSECTION; MIDDLE AGED; POLYMERASE CHAIN REACTION; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN;

EID: 34748861564     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/PAS.0b013e31804bdaf8     Document Type: Article

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