B-cell lymphoma associated with chronic lymphatic leukaemia: Two cases with contrasting aggressive and indolent behaviour

British Journal of Dermatology

Volumn 140, Issue 4, 1999, Pages 708-714

  Ratnavel, R C ^a,c   Dunn Walters, D K ^b   Boursier, L ^b   Frazer Andrews, E ^a   Orchard, G ^a   Russell Jones, R ^a   Calonje, E ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c STOKE MANDEVILLE HOSPITAL   (United Kingdom)

Author keywords

B cell lymphoma; Chronic lymphatic leukaemia; Immunoglobulin gene rearrangement; Richter's syndrome

Indexed keywords

AGED; ARTICLE; B CELL LYMPHOMA; CASE REPORT; CHRONIC LYMPHATIC LEUKEMIA; DISEASE ASSOCIATION; FEMALE; GENE REARRANGEMENT; GENE SEQUENCE; HUMAN; IMMUNOGLOBULIN GENE; IMMUNOPHENOTYPING; MALE; MOLECULAR CLONING; PRIORITY JOURNAL; SKIN LYMPHOMA;

AGED; FEMALE; GENE REARRANGEMENT; GENES, IMMUNOGLOBULIN; HUMANS; LEUKEMIA, LYMPHOCYTIC, CHRONIC; LYMPHOMA, B-CELL; MALE; SKIN NEOPLASMS;

EID: 0032935259     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2133.1999.02776.x     Document Type: Article

References (23)

1. 1 Richter MN. Generalized reticular cell sarcoma of lymph nodes associated with lymphatic leukemia. Am J Pathol 1928; 4: 285-92.
2. 2 Harousseau JL, Flandrin G, Tricot G et al. Malignant lymphoma supervening in chronic lymphocytic lymphoma and related disorders. Richter's syndrome: a study of 25 cases. Cancer 1981; 46: 118-14.
3. 3 Robertson LE, Pugh W, O'Brien S et al. Richter's syndrome: a report on 39 patients. J Clin Oncol 1993; 11: 1985-9.
4. 4 Novice FM, Mikhail GR, Maeda K, Hawley RG. Richter's syndrome presenting as a solitary cutaneous nodule. Int J Dermatol 1989; 28: 36-7.
5. 5 Zarco C, Lahuerta-Palacios JJ, Borrego L et al. Centroblastic transformation of chronic lymphocytic leukaemia with primary skin involvement - cutaneous presentation of Richter's syndrome. Clin Exp Dermatol 1993; 18: 263-7.
6. 6 Cerroni L, Zenahlik P, Höfler G et al. Specific cutaneous infiltrates of B-cell chronic lymphocytic leukaemia. A clinicopathological and prognostic study of 42 patients. Am J Surg Pathol 1996; 20: 1000-10.
7. 7 Bessudo A, Kipps TJ. Origin of high-grade lymphomas in Richter syndrome. Leuk Lymph 1995; 18: 367-72.
8. 8 Nowell P, Finan J, Glover D, Guerry D. Cytogenetic evidence for the clonal nature of Richter's syndrome. Blood 1981; 58: 183-6.
9. 9 Delsol G, Laurent G, Kuhlein E et al. Richter's syndrome. Evidence for the clonal origin of the two populations. Am J Clin Pathol 1981; 76: 308-15.
10. 10 Suster S, Rywlin AM. A reappraisal of Richter's syndrome. Development of two phenotypically distinctive cell lines in a case of chronic lymphocytic leukaemia. Cancer 1987; 59: 1412-18.
11. 11 Tonegawa S. Somatic generation of antibody diversity. Nature 1983; 302: 575-81.
12. 12 Seidman JG, Leder P. The arrangement and rearrangement of antibody genes. Nature 1978; 276: 790-5.
13. 13 Nakamine H, Maish AS, Sanger WG et al. Richter's syndrome with different immunoglobulin light chain types. Molecular and cytogenetic features indicate a common clonal origin. Am J Clin Pathol 1992; 97: 656-63.
14. 14 van Dongen JJ, Hooijkaas H, Michiels JJ et al. Richter's syndrome with different immunoglobulin light chains and different heavy chain gene rearrangements. Blood 1984; 64: 571-5.
15. 15 Fraitag S, Bodemer C, Rousselot P et al. Transformation cutanée d'une leucémie lymphoïde chronique en lymphome immunoblastique. Présentation cutanée d'un syndrome de Richter. Ann Dermatol Venerol 1995; 122: 530-3.
16. 16 Cherepakhin V, Baird SM, Meisenholder GW, Kipps TJ. Common clonal origin of chronic lymphocytic leukaemia and high grade lymphoma of Richter's syndrome. Blood 1993; 82: 3141-7.
17. 17 Matolesy A, Inghirami G, Knowles DM. Molecular genetic demonstration of the diverse evolution of Richter's syndrome (chronic lymphocytic leukemia and subsequent large cell lymphoma). Blood 1994; 83: 1363-72.
18. 18 Millar SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988; 16: 1215-18.
19. 19 Wan JH, Trainor KJ, Brisco MJ, Morley AA. Monoclonality in B cell lymphoma detected in paraffin wax embedded sections using the polymerase chain reaction. J Clin Pathol 1990; 43: 888-90.
20. 20 Diss TC, Peng H-Z, Wotherspoon AC et al. Detection of monocloriality in low-grade B cell lymphomas using the polymerase chain reaction is dependent on primer selection and lymphoma type. J Pathol 1993; 169: 291-5.
21. 21 Dunn-Walters DK, Isaacson PG, Spencer L. Sequence analysis of human IgVH genes indicates that ileal lamina propria plasma cells are derived from Peyer's patches. Eur J Immunol 1997; 27: 363-7.
22. 22 Travis LB, Curtis RE, Hankey BF, Fraumeni JF Jr. Second cancers in patients with chronic lymphocytic leukemia. J Natl Cancer Inst 1992; 84: 1422-7.
23. 23 Dunn-Walters DK, Howe CJ, Isaacson PG, Spencer J. Location and sequence of rearranged Ig genes in human thymus. Eur J Immunol 1995; 25: 513-19.