-
2
-
-
0034468560
-
Repair of gaps in retroviral DNA integration intermediates
-
Yoder KE, Bushman FD, (2000) Repair of gaps in retroviral DNA integration intermediates. J Virol 74: 11191-11200.
-
(2000)
J Virol
, vol.74
, pp. 11191-11200
-
-
Yoder, K.E.1
Bushman, F.D.2
-
3
-
-
39349097864
-
Identification of host proteins required for HIV infection through a functional genomic screen
-
Brass AL, Dykxhoorn DM, Benita Y, Yan N, Engelman A, et al. (2008) Identification of host proteins required for HIV infection through a functional genomic screen. Science 319: 921-926.
-
(2008)
Science
, vol.319
, pp. 921-926
-
-
Brass, A.L.1
Dykxhoorn, D.M.2
Benita, Y.3
Yan, N.4
Engelman, A.5
-
4
-
-
52949130695
-
Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication
-
Konig R, Zhou Y, Elleder D, Diamond TL, Bonamy GM, et al. (2008) Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication. Cell 135: 49-60.
-
(2008)
Cell
, vol.135
, pp. 49-60
-
-
Konig, R.1
Zhou, Y.2
Elleder, D.3
Diamond, T.L.4
Bonamy, G.M.5
-
5
-
-
55249088255
-
Genome-scale RNAi screen for host factors required for HIV replication
-
Zhou H, Xu M, Huang Q, Gates AT, Zhang XD, et al. (2008) Genome-scale RNAi screen for host factors required for HIV replication. Cell Host Microbe 4: 495-504.
-
(2008)
Cell Host Microbe
, vol.4
, pp. 495-504
-
-
Zhou, H.1
Xu, M.2
Huang, Q.3
Gates, A.T.4
Zhang, X.D.5
-
6
-
-
79952952293
-
siRNA screening of a targeted library of DNA repair factors in HIV infection reveals a role for base excision repair in HIV integration
-
submitted
-
Espeseth AS, Fishel R, Hazuda D, Huang Q, Xu M, et al. (2010) siRNA screening of a targeted library of DNA repair factors in HIV infection reveals a role for base excision repair in HIV integration. submitted.
-
(2010)
-
-
Espeseth, A.S.1
Fishel, R.2
Hazuda, D.3
Huang, Q.4
Xu, M.5
-
7
-
-
0004228157
-
-
Washington, D.C., ASM Press
-
Friedberg EC, Walker GC, Siede W, Wood RD, Schultz RA, et al. (2006) DNA Repair and Mutagenesis Washington, D.C. ASM Press.
-
(2006)
DNA Repair and Mutagenesis
-
-
Friedberg, E.C.1
Walker, G.C.2
Siede, W.3
Wood, R.D.4
Schultz, R.A.5
-
8
-
-
38049112778
-
Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells
-
Hegde ML, Hazra TK, Mitra S, (2008) Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells. Cell Res 18: 27-47.
-
(2008)
Cell Res
, vol.18
, pp. 27-47
-
-
Hegde, M.L.1
Hazra, T.K.2
Mitra, S.3
-
9
-
-
30344455023
-
Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage Version 7
-
Friedberg EC, Meira LB, (2006) Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage Version 7. DNA Repair (Amst) 5: 189-209.
-
(2006)
DNA Repair (Amst)
, vol.5
, pp. 189-209
-
-
Friedberg, E.C.1
Meira, L.B.2
-
10
-
-
33646589977
-
Early embryonic lethality due to targeted inactivation of DNA ligase III
-
Puebla-Osorio N, Lacey DB, Alt FW, Zhu C, (2006) Early embryonic lethality due to targeted inactivation of DNA ligase III. Mol Cell Biol 26: 3935-3941.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 3935-3941
-
-
Puebla-Osorio, N.1
Lacey, D.B.2
Alt, F.W.3
Zhu, C.4
-
11
-
-
0030030379
-
Requirement of mammalian DNA polymerase-beta in base-excision repair
-
Sobol RW, Horton JK, Kuhn R, Gu H, Singhal RK, et al. (1996) Requirement of mammalian DNA polymerase-beta in base-excision repair. Nature 379: 183-186.
-
(1996)
Nature
, vol.379
, pp. 183-186
-
-
Sobol, R.W.1
Horton, J.K.2
Kuhn, R.3
Gu, H.4
Singhal, R.K.5
-
12
-
-
17644365775
-
Two essential but distinct functions of the mammalian abasic endonuclease
-
Izumi T, Brown DB, Naidu CV, Bhakat KK, Macinnes MA, et al. (2005) Two essential but distinct functions of the mammalian abasic endonuclease. Proc Natl Acad Sci U S A 102: 5739-5743.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 5739-5743
-
-
Izumi, T.1
Brown, D.B.2
Naidu, C.V.3
Bhakat, K.K.4
Macinnes, M.A.5
-
13
-
-
0033561152
-
Requirement for the Xrcc1 DNA base excision repair gene during early mouse development
-
Tebbs RS, Flannery ML, Meneses JJ, Hartmann A, Tucker JD, et al. (1999) Requirement for the Xrcc1 DNA base excision repair gene during early mouse development. Dev Biol 208: 513-529.
-
(1999)
Dev Biol
, vol.208
, pp. 513-529
-
-
Tebbs, R.S.1
Flannery, M.L.2
Meneses, J.J.3
Hartmann, A.4
Tucker, J.D.5
-
14
-
-
0033539610
-
Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage
-
Klungland A, Rosewell I, Hollenbach S, Larsen E, Daly G, et al. (1999) Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage. Proc Natl Acad Sci U S A 96: 13300-13305.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 13300-13305
-
-
Klungland, A.1
Rosewell, I.2
Hollenbach, S.3
Larsen, E.4
Daly, G.5
-
15
-
-
32444434993
-
The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase
-
Vartanian V, Lowell B, Minko IG, Wood TG, Ceci JD, et al. (2006) The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase. Proc Natl Acad Sci U S A 103: 1864-1869.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 1864-1869
-
-
Vartanian, V.1
Lowell, B.2
Minko, I.G.3
Wood, T.G.4
Ceci, J.D.5
-
16
-
-
2342520175
-
Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors
-
Xie Y, Yang H, Cunanan C, Okamoto K, Shibata D, et al. (2004) Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors. Cancer Res 64: 3096-3102.
-
(2004)
Cancer Res
, vol.64
, pp. 3096-3102
-
-
Xie, Y.1
Yang, H.2
Cunanan, C.3
Okamoto, K.4
Shibata, D.5
-
17
-
-
66249146924
-
Role of MUTYH and MSH2 in the control of oxidative DNA damage, genetic instability, and tumorigenesis
-
Russo MT, De Luca G, Casorelli I, Degan P, Molatore S, et al. (2009) Role of MUTYH and MSH2 in the control of oxidative DNA damage, genetic instability, and tumorigenesis. Cancer Res 69: 4372-4379.
-
(2009)
Cancer Res
, vol.69
, pp. 4372-4379
-
-
Russo, M.T.1
de Luca, G.2
Casorelli, I.3
Degan, P.4
Molatore, S.5
-
18
-
-
34247599335
-
A unified view of base excision repair: lesion-dependent protein complexes regulated by post-translational modification
-
Almeida KH, Sobol RW, (2007) A unified view of base excision repair: lesion-dependent protein complexes regulated by post-translational modification. DNA Repair (Amst) 6: 695-711.
-
(2007)
DNA Repair (Amst)
, vol.6
, pp. 695-711
-
-
Almeida, K.H.1
Sobol, R.W.2
-
19
-
-
3042739635
-
Accumulation of the oxidative base lesion 8-hydroxyguanine in DNA of tumor-prone mice defective in both the Myh and Ogg1 DNA glycosylases
-
Russo MT, De Luca G, Degan P, Parlanti E, Dogliotti E, et al. (2004) Accumulation of the oxidative base lesion 8-hydroxyguanine in DNA of tumor-prone mice defective in both the Myh and Ogg1 DNA glycosylases. Cancer Res 64: 4411-4414.
-
(2004)
Cancer Res
, vol.64
, pp. 4411-4414
-
-
Russo, M.T.1
de Luca, G.2
Degan, P.3
Parlanti, E.4
Dogliotti, E.5
-
20
-
-
41949100227
-
Cells deficient in oxidative DNA damage repair genes Myh and Ogg1 are sensitive to oxidants with increased G2/M arrest and multinucleation
-
Xie Y, Yang H, Miller JH, Shih DM, Hicks GG, et al. (2008) Cells deficient in oxidative DNA damage repair genes Myh and Ogg1 are sensitive to oxidants with increased G2/M arrest and multinucleation. Carcinogenesis 29: 722-728.
-
(2008)
Carcinogenesis
, vol.29
, pp. 722-728
-
-
Xie, Y.1
Yang, H.2
Miller, J.H.3
Shih, D.M.4
Hicks, G.G.5
-
21
-
-
22244448679
-
The role of base excision repair in the sensitivity and resistance to temozolomide-mediated cell death
-
Trivedi RN, Almeida KH, Fornsaglio JL, Schamus S, Sobol RW, (2005) The role of base excision repair in the sensitivity and resistance to temozolomide-mediated cell death. Cancer Res 65: 6394-6400.
-
(2005)
Cancer Res
, vol.65
, pp. 6394-6400
-
-
Trivedi, R.N.1
Almeida, K.H.2
Fornsaglio, J.L.3
Schamus, S.4
Sobol, R.W.5
-
22
-
-
0036195928
-
Human immunodeficiency virus cDNA metabolism: notable stability of two-long terminal repeat circles
-
Butler SL, Johnson EP, Bushman FD, (2002) Human immunodeficiency virus cDNA metabolism: notable stability of two-long terminal repeat circles. J Virol 76: 3739-3747.
-
(2002)
J Virol
, vol.76
, pp. 3739-3747
-
-
Butler, S.L.1
Johnson, E.P.2
Bushman, F.D.3
-
23
-
-
0029795285
-
Murine leukemia virus-based Tat-inducible long terminal repeat replacement vectors: a new system for anti-human immunodeficiency virus gene therapy
-
Cannon PM, Kim N, Kingsman SM, Kingsman AJ, (1996) Murine leukemia virus-based Tat-inducible long terminal repeat replacement vectors: a new system for anti-human immunodeficiency virus gene therapy. J Virol 70: 8234-8240.
-
(1996)
J Virol
, vol.70
, pp. 8234-8240
-
-
Cannon, P.M.1
Kim, N.2
Kingsman, S.M.3
Kingsman, A.J.4
-
24
-
-
0034040751
-
Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences
-
Follenzi A, Ailles LE, Bakovic S, Geuna M, Naldini L, (2000) Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences. Nat Genet 25: 217-222.
-
(2000)
Nat Genet
, vol.25
, pp. 217-222
-
-
Follenzi, A.1
Ailles, L.E.2
Bakovic, S.3
Geuna, M.4
Naldini, L.5
-
25
-
-
0031953134
-
Efficient transduction of nondividing human cells by feline immunodeficiency virus lentiviral vectors
-
Poeschla EM, Wong-Staal F, Looney DJ, (1998) Efficient transduction of nondividing human cells by feline immunodeficiency virus lentiviral vectors. Nat Med 4: 354-357.
-
(1998)
Nat Med
, vol.4
, pp. 354-357
-
-
Poeschla, E.M.1
Wong-Staal, F.2
Looney, D.J.3
-
26
-
-
0030819379
-
Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo
-
Zufferey R, Nagy D, Mandel RJ, Naldini L, Trono D, (1997) Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo. Nat Biotechnol 15: 871-875.
-
(1997)
Nat Biotechnol
, vol.15
, pp. 871-875
-
-
Zufferey, R.1
Nagy, D.2
Mandel, R.J.3
Naldini, L.4
Trono, D.5
-
27
-
-
0032582688
-
Processing of an HIV replication intermediate by the human DNA replication enzyme FEN1
-
Rumbaugh JA, Fuentes GM, Bambara RA, (1998) Processing of an HIV replication intermediate by the human DNA replication enzyme FEN1. J Biol Chem 273: 28740-28745.
-
(1998)
J Biol Chem
, vol.273
, pp. 28740-28745
-
-
Rumbaugh, J.A.1
Fuentes, G.M.2
Bambara, R.A.3
-
28
-
-
0035025888
-
A quantitative assay for HIV DNA integration in vivo
-
Butler SL, Hansen MS, Bushman FD, (2001) A quantitative assay for HIV DNA integration in vivo. Nat Med 7: 631-634.
-
(2001)
Nat Med
, vol.7
, pp. 631-634
-
-
Butler, S.L.1
Hansen, M.S.2
Bushman, F.D.3
-
29
-
-
63449120803
-
The SET complex acts as a barrier to autointegration of HIV-1
-
Yan N, Cherepanov P, Daigle JE, Engelman A, Lieberman J, (2009) The SET complex acts as a barrier to autointegration of HIV-1. PLoS Pathog 5: e1000327.
-
(2009)
PLoS Pathog
, vol.5
-
-
Yan, N.1
Cherepanov, P.2
Daigle, J.E.3
Engelman, A.4
Lieberman, J.5
-
31
-
-
0026770379
-
Active nuclear import of human immunodeficiency virus type 1 preintegration complexes
-
Bukrinsky MI, Sharova N, Dempsey MP, Stanwick TL, Bukrinskaya AG, et al. (1992) Active nuclear import of human immunodeficiency virus type 1 preintegration complexes. Proc Natl Acad Sci U S A 89: 6580-6584.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 6580-6584
-
-
Bukrinsky, M.I.1
Sharova, N.2
Dempsey, M.P.3
Stanwick, T.L.4
Bukrinskaya, A.G.5
-
32
-
-
0141457701
-
Analysis of early human immunodeficiency virus type 1 DNA synthesis by use of a new sensitive assay for quantifying integrated provirus
-
Brussel A, Sonigo P, (2003) Analysis of early human immunodeficiency virus type 1 DNA synthesis by use of a new sensitive assay for quantifying integrated provirus. J Virol 77: 10119-10124.
-
(2003)
J Virol
, vol.77
, pp. 10119-10124
-
-
Brussel, A.1
Sonigo, P.2
-
33
-
-
0033021533
-
Integration complexes derived from HIV vectors for rapid assays in vitro
-
Hansen MS, Smith GJ 3rd, Kafri T, Molteni V, Siegel JS, et al. (1999) Integration complexes derived from HIV vectors for rapid assays in vitro. Nat Biotechnol 17: 578-582.
-
(1999)
Nat Biotechnol
, vol.17
, pp. 578-582
-
-
Hansen, M.S.1
Smith 3rd, G.J.2
Kafri, T.3
Molteni, V.4
Siegel, J.S.5
-
34
-
-
0025337327
-
Human immunodeficiency virus integration in a cell-free system
-
Ellison V, Abrams H, Roe T, Lifson J, Brown P, (1990) Human immunodeficiency virus integration in a cell-free system. J Virol 64: 2711-2715.
-
(1990)
J Virol
, vol.64
, pp. 2711-2715
-
-
Ellison, V.1
Abrams, H.2
Roe, T.3
Lifson, J.4
Brown, P.5
-
35
-
-
0025313138
-
Integration of human immunodeficiency virus type 1 DNA in vitro
-
Farnet CM, Haseltine WA, (1990) Integration of human immunodeficiency virus type 1 DNA in vitro. Proc Natl Acad Sci U S A 87: 4164-4168.
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 4164-4168
-
-
Farnet, C.M.1
Haseltine, W.A.2
-
36
-
-
34447513231
-
LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration
-
Shun MC, Raghavendra NK, Vandegraaff N, Daigle JE, Hughes S, et al. (2007) LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration. Genes Dev 21: 1767-1778.
-
(2007)
Genes Dev
, vol.21
, pp. 1767-1778
-
-
Shun, M.C.1
Raghavendra, N.K.2
Vandegraaff, N.3
Daigle, J.E.4
Hughes, S.5
-
37
-
-
33750358735
-
An essential role for LEDGF/p75 in HIV integration
-
Llano M, Saenz DT, Meehan A, Wongthida P, Peretz M, et al. (2006) An essential role for LEDGF/p75 in HIV integration. Science 314: 461-464.
-
(2006)
Science
, vol.314
, pp. 461-464
-
-
Llano, M.1
Saenz, D.T.2
Meehan, A.3
Wongthida, P.4
Peretz, M.5
-
38
-
-
0345306577
-
Construction and analysis of cells lacking the HMGA gene family
-
Beitzel B, Bushman F, (2003) Construction and analysis of cells lacking the HMGA gene family. Nucleic Acids Res 31: 5025-5032.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 5025-5032
-
-
Beitzel, B.1
Bushman, F.2
-
39
-
-
0032433829
-
The barrier-to-autointegration protein is a host factor for HIV type 1 integration
-
Chen H, Engelman A, (1998) The barrier-to-autointegration protein is a host factor for HIV type 1 integration. Proc Natl Acad Sci U S A 95: 15270-15274.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 15270-15274
-
-
Chen, H.1
Engelman, A.2
-
40
-
-
0031004162
-
HIV-1 cDNA integration: requirement of HMG I(Y) protein for function of preintegration complexes in vitro
-
Farnet CM, Bushman FD, (1997) HIV-1 cDNA integration: requirement of HMG I(Y) protein for function of preintegration complexes in vitro. Cell 88: 483-492.
-
(1997)
Cell
, vol.88
, pp. 483-492
-
-
Farnet, C.M.1
Bushman, F.D.2
-
41
-
-
33845788704
-
Wild-type levels of human immunodeficiency virus type 1 infectivity in the absence of cellular emerin protein
-
Shun MC, Daigle JE, Vandegraaff N, Engelman A, (2007) Wild-type levels of human immunodeficiency virus type 1 infectivity in the absence of cellular emerin protein. J Virol 81: 166-172.
-
(2007)
J Virol
, vol.81
, pp. 166-172
-
-
Shun, M.C.1
Daigle, J.E.2
Vandegraaff, N.3
Engelman, A.4
-
42
-
-
17844381584
-
Symmetrical base preferences surrounding HIV-1, avian sarcoma/leukosis virus, and murine leukemia virus integration sites
-
Holman AG, Coffin JM, (2005) Symmetrical base preferences surrounding HIV-1, avian sarcoma/leukosis virus, and murine leukemia virus integration sites. Proc Natl Acad Sci U S A 102: 6103-6107.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 6103-6107
-
-
Holman, A.G.1
Coffin, J.M.2
-
43
-
-
16244386233
-
Weak palindromic consensus sequences are a common feature found at the integration target sites of many retroviruses
-
Wu X, Li Y, Crise B, Burgess SM, Munroe DJ, (2005) Weak palindromic consensus sequences are a common feature found at the integration target sites of many retroviruses. J Virol 79: 5211-5214.
-
(2005)
J Virol
, vol.79
, pp. 5211-5214
-
-
Wu, X.1
Li, Y.2
Crise, B.3
Burgess, S.M.4
Munroe, D.J.5
-
44
-
-
33847374745
-
Methods for studying pro- and antiapoptotic genes in nonimmortal cells
-
McCurrach ME, Lowe SW, (2001) Methods for studying pro- and antiapoptotic genes in nonimmortal cells. Methods Cell Biol 66: 197-227.
-
(2001)
Methods Cell Biol
, vol.66
, pp. 197-227
-
-
McCurrach, M.E.1
Lowe, S.W.2
-
45
-
-
0034659935
-
The lyase activity of the DNA repair protein beta-polymerase protects from DNA-damage-induced cytotoxicity
-
Sobol RW, Prasad R, Evenski A, Baker A, Yang XP, et al. (2000) The lyase activity of the DNA repair protein beta-polymerase protects from DNA-damage-induced cytotoxicity. Nature 405: 807-810.
-
(2000)
Nature
, vol.405
, pp. 807-810
-
-
Sobol, R.W.1
Prasad, R.2
Evenski, A.3
Baker, A.4
Yang, X.P.5
-
46
-
-
33845732323
-
DNA polymerase beta null mouse embryonic fibroblasts harbor a homozygous null mutation in DNA polymerase iota
-
Sobol RW, (2007) DNA polymerase beta null mouse embryonic fibroblasts harbor a homozygous null mutation in DNA polymerase iota. DNA Repair (Amst) 6: 3-7.
-
(2007)
DNA Repair (Amst)
, vol.6
, pp. 3-7
-
-
Sobol, R.W.1
-
47
-
-
0141650595
-
Comparison of transfection conditions for a lentivirus vector produced in large volumes
-
Karolewski BA, Watson DJ, Parente MK, Wolfe JH, (2003) Comparison of transfection conditions for a lentivirus vector produced in large volumes. Hum Gene Ther 14: 1287-1296.
-
(2003)
Hum Gene Ther
, vol.14
, pp. 1287-1296
-
-
Karolewski, B.A.1
Watson, D.J.2
Parente, M.K.3
Wolfe, J.H.4
-
48
-
-
0037162715
-
HIV-1 integration in the human genome favors active genes and local hotspots
-
Schroder AR, Shinn P, Chen H, Berry C, Ecker JR, et al. (2002) HIV-1 integration in the human genome favors active genes and local hotspots. Cell 110: 521-529.
-
(2002)
Cell
, vol.110
, pp. 521-529
-
-
Schroder, A.R.1
Shinn, P.2
Chen, H.3
Berry, C.4
Ecker, J.R.5
-
49
-
-
0023839680
-
Expression of human DNA polymerase beta in Escherichia coli and characterization of the recombinant enzyme
-
Abbotts J, SenGupta DN, Zmudzka B, Widen SG, Notario V, et al. (1988) Expression of human DNA polymerase beta in Escherichia coli and characterization of the recombinant enzyme. Biochemistry 27: 901-909.
-
(1988)
Biochemistry
, vol.27
, pp. 901-909
-
-
Abbotts, J.1
SenGupta, D.N.2
Zmudzka, B.3
Widen, S.G.4
Notario, V.5
-
50
-
-
0028803178
-
Purification and domain-mapping of mammalian DNA polymerase beta
-
Beard WA, Wilson SH, (1995) Purification and domain-mapping of mammalian DNA polymerase beta. Methods Enzymol 262: 98-107.
-
(1995)
Methods Enzymol
, vol.262
, pp. 98-107
-
-
Beard, W.A.1
Wilson, S.H.2
|