-
1
-
-
0030954732
-
A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease
-
Crohn's Disease cA2 Study Group
-
Targan SR, Hanauer SB, van Deventer SJ, et al. A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group. N Engl J Med 1997;337:1029-1035.
-
(1997)
N Engl J Med
, vol.337
, pp. 1029-1035
-
-
Targan, S.R.1
Hanauer, S.B.2
Van Deventer, S.J.3
-
2
-
-
77950857047
-
Emerging biologics in the treatment of inflammatory bowel disease: What is around the corner?
-
Fiorino G, Rovida S, Correale C, Malesci A, Danese S. Emerging biologics in the treatment of inflammatory bowel disease: what is around the corner? Curr Drug Targets 2010;11:249-260.
-
(2010)
Curr Drug Targets
, vol.11
, pp. 249-260
-
-
Fiorino, G.1
Rovida, S.2
Correale, C.3
Malesci, A.4
Danese, S.5
-
3
-
-
0037018761
-
Maintenance infliximab for Crohn's disease: The ACCENT I randomised trial
-
DOI 10.1016/S0140-6736(02)08512-4
-
Hanauer SB, Feagan BG, Lichtenstein GR, et al. Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial. Lancet 2002;359:1541-1549. (Pubitemid 34621118)
-
(2002)
Lancet
, vol.359
, Issue.9317
, pp. 1541-1549
-
-
Hanauer, S.B.1
Feagan, B.G.2
Lichtenstein, G.R.3
Mayer, L.F.4
Schreiber, S.5
Colombel, J.F.6
Rachmilewitz, D.7
Wolf, D.C.8
Olson, A.9
Bao, W.10
Rutgeerts, P.11
-
4
-
-
34548476476
-
+ T-cell subsets in patients with ulcerative colitis: Modified by selective granulocyte and monocyte adsorption apheresis
-
DOI 10.1007/s10620-006-9560-z
-
Yokoyama Y, Fukunaga K, Fukuda Y, et al. Demonstration of lowregulatory CD25High+CD4+ and high-pro-inflammatory CD28- CD4+ T-Cell subsets in patients with ulcerative colitis: modified by selective granulocyte and monocyte adsorption apheresis. Dig Dis Sci 2007;52:2725-2731. (Pubitemid 47373881)
-
(2007)
Digestive Diseases and Sciences
, vol.52
, Issue.10
, pp. 2725-2731
-
-
Yokoyama, Y.1
Fukunaga, K.2
Fukuda, Y.3
Tozawa, K.4
Kamikozuru, K.5
Ohnishi, K.6
Kusaka, T.7
Kosaka, T.8
Hida, N.9
Ohda, Y.10
Miwa, H.11
Matsumoto, T.12
-
5
-
-
64649100879
-
The expression profile of functional regulatory T cells, CD4+CD25high+/forkhead box protein P3+, in patients with ulcerative colitis during active and quiescent disease
-
Kamikozuru K, Fukunaga K, Hirota S, et al. The expression profile of functional regulatory T cells, CD4+CD25high+/forkhead box protein P3+, in patients with ulcerative colitis during active and quiescent disease. Clin Exp Immunol 2009;156:320-327.
-
(2009)
Clin Exp Immunol
, vol.156
, pp. 320-327
-
-
Kamikozuru, K.1
Fukunaga, K.2
Hirota, S.3
-
6
-
-
0002063230
-
A simple classification of Crohn's disease: Report of the Working Party for the World Congresses of Gastroenterology, Vienna 1998
-
Gasche C, Scholmerich J, Brynskov J, et al. A simple classification of Crohn's disease: report of the Working Party for the World Congresses of Gastroenterology, Vienna 1998. Inflamm Bowel Dis 2000;6:8-15.
-
(2000)
Inflamm Bowel Dis
, vol.6
, pp. 8-15
-
-
Gasche, C.1
Scholmerich, J.2
Brynskov, J.3
-
7
-
-
33144463875
-
European evidence based consensus on the diagnosis and management of Crohn's disease: Special situations
-
DOI 10.1136/gut.2005.081950c
-
Caprilli R, Gassull MA, Escher JC, et al. European evidence based consensus on the diagnosis and management of Crohn's disease: special situations. Gut 2006;55 Suppl 1:i36-i58. (Pubitemid 43268292)
-
(2006)
Gut
, vol.55
, Issue.SUPPL. 1
-
-
Caprilli, R.1
Gassull, M.A.2
Escher, J.C.3
Moser, G.4
Munkholm, P.5
Forbes, A.6
Hommes, D.W.7
Lochs, H.8
Angelucci, E.9
Cocco, A.10
Vucelic, B.11
Hildebrand, H.12
Kolacek, S.13
Riis, L.14
Lukas, M.15
De Franchis, R.16
Hamilton, M.17
Jantschek, G.18
Michetti, P.19
O'Morain, C.20
Anwar, M.M.21
Freitas, J.L.22
Mouzas, I.A.23
Baert, F.24
Mitchell, R.25
Hawkey, C.J.26
Travis, S.P.L.27
Stange, E.F.28
more..
-
8
-
-
0018292706
-
National cooperative Crohn's disease study: Study design and conduct of the study
-
Winship DH, Summers RW, Singleton JW, et al. National Cooperative Crohn's Disease Study: study design and conduct of the study. Gastroenterology 1979;77(4 Pt 2):829-842. (Pubitemid 9257851)
-
(1979)
Gastroenterology
, vol.77
, Issue.4 II
, pp. 829-842
-
-
Winship, D.H.1
Summers, R.W.2
Singleton, J.W.3
-
9
-
-
69449091637
-
Modulation of the Th1/Th2 balance by infliximab improves hyperthyroidism associated with a flare-up of ulcerative colitis
-
Matsumura K, Nakase H, Yamamoto S, et al. Modulation of the Th1/Th2 balance by infliximab improves hyperthyroidism associated with a flare-up of ulcerative colitis. Inflamm Bowel Dis 2009;15:967-968.
-
(2009)
Inflamm Bowel Dis
, vol.15
, pp. 967-968
-
-
Matsumura, K.1
Nakase, H.2
Yamamoto, S.3
-
10
-
-
0028047268
-
Quality of life: A valid and reliable measure of therapeutic efficacy in the treatment of inflammatory bowel disease
-
Irvine EJ, Feagan B, Rochon J, et al. Quality of life: a valid and reliable measure of therapeutic efficacy in the treatment of inflammatory bowel disease. Canadian Crohn's Relapse Prevention Trial Study Group. Gastroenterology 1994;106:287-296. (Pubitemid 24041204)
-
(1994)
Gastroenterology
, vol.106
, Issue.2
, pp. 287-296
-
-
Irvine, E.J.1
Feagan, B.2
Rochon, J.3
Archambault, A.4
Fedorak, R.N.5
Groll, A.6
Kinnear, D.7
Saibil, F.8
Mcdonald, J.W.D.9
-
11
-
-
70349967965
-
Anti-TNF biologic agents: Still the therapy of choice for rheumatoid arthritis
-
Taylor PC, Feldmann M. Anti-TNF biologic agents: still the therapy of choice for rheumatoid arthritis. Nat Rev Rheumatol 2009;5:578-582.
-
(2009)
Nat Rev Rheumatol
, vol.5
, pp. 578-582
-
-
Taylor, P.C.1
Feldmann, M.2
-
12
-
-
0031781603
-
Inflammatory bowel disease: Etiology and pathogenesis
-
DOI 10.1016/S0016-5085(98)70381-6
-
Fiocchi C. Inflammatory bowel disease: etiology and pathogenesis. Gastroenterology 1998;115:182-205. (Pubitemid 28307304)
-
(1998)
Gastroenterology
, vol.115
, Issue.1
, pp. 182-205
-
-
Fiocchi, C.1
-
13
-
-
44049104564
-
H-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat
-
DOI 10.1038/ni.1610, PII NI.1610
-
Manel N, Unutmaz D, Littman DR. The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat. Nat Immunol 2008;9:641-649. (Pubitemid 351714729)
-
(2008)
Nature Immunology
, vol.9
, Issue.6
, pp. 641-649
-
-
Manel, N.1
Unutmaz, D.2
Littman, D.R.3
-
14
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
Bettelli E, Carrier Y, Gao W, et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006;441:235-238.
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
-
15
-
-
70350165074
-
Plasma transforming growth factor-beta1 level in inflammatory bowel disease
-
Kiliç ZM, Ayaz S, Ozin Y, Nadir I, Cakal B, Ulker A. Plasma transforming growth factor-beta1 level in inflammatory bowel disease. Turk J Gastroenterol 2009;20:165-170.
-
(2009)
Turk J Gastroenterol
, vol.20
, pp. 165-170
-
-
Kiliç, Z.M.1
Ayaz, S.2
Ozin, Y.3
Nadir, I.4
Cakal, B.5
Ulker, A.6
-
16
-
-
62949223226
-
Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression
-
Fantini MC, Rizzo A, Fina D, et al. Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression. Gastroenterology 2009;136:1308-1316, e1-e3.
-
(2009)
Gastroenterology
, vol.136
-
-
Fantini, M.C.1
Rizzo, A.2
Fina, D.3
-
17
-
-
47549112840
-
IL-21 and TGFbeta are required for differentiation of human T(H)17 cells
-
Yang L, Anderson DE, Baecher-Allan C, et al. IL-21 and TGFbeta are required for differentiation of human T(H)17 cells. Nature 2008;454:350-352.
-
(2008)
Nature
, vol.454
, pp. 350-352
-
-
Yang, L.1
Anderson, D.E.2
Baecher-Allan, C.3
-
18
-
-
0348223787
-
+ Regulatory T Cells by TGF-beta Induction of Transcription Factor Foxp3
-
DOI 10.1084/jem.20030152
-
Chen W, Jin W, Hardegen N, et al. Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med 2003;198:1875-1886. (Pubitemid 38032120)
-
(2003)
Journal of Experimental Medicine
, vol.198
, Issue.12
, pp. 1875-1886
-
-
Chen, W.1
Jin, W.2
Hardegen, N.3
Lei, K.-J.4
Li, L.5
Marinos, N.6
McGrady, G.7
Wahl, S.M.8
-
19
-
-
0037013930
-
Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation
-
DOI 10.1084/jem.20012076
-
Gorelik L, Constant S, Flavell RA. Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation. J Exp Med 2002;195:1499-1505. (Pubitemid 34602827)
-
(2002)
Journal of Experimental Medicine
, vol.195
, Issue.11
, pp. 1499-1505
-
-
Gorelik, L.1
Constant, S.2
Flavell, R.A.3
-
20
-
-
0035413350
-
high regulatory cells in human peripheral blood
-
Baecher-Allan C, Brown JA, Freeman GJ, Hafler DA. CD4+CD25high regulatory cells in human peripheral blood. J Immunol 2001;167:1245-1253. (Pubitemid 32703119)
-
(2001)
Journal of Immunology
, vol.167
, Issue.3
, pp. 1245-1253
-
-
Baecher-Allan, C.1
Brown, J.A.2
Freeman, G.J.3
Hafler, D.A.4
-
21
-
-
70149087732
-
Diminution of Circulating CD4+CD25 high T cells in naïve Crohn's disease
-
Chamouard P, Monneaux F, Richert Z, et al. Diminution of Circulating CD4+CD25 high T cells in naïve Crohn's disease. Dig Dis Sci 2009;54:2084-2093.
-
(2009)
Dig Dis Sci
, vol.54
, pp. 2084-2093
-
-
Chamouard, P.1
Monneaux, F.2
Richert, Z.3
-
22
-
-
0034144269
-
Chemokines: A new classification system and their role in immunity
-
Zlotnik A, Yoshie O. Chemokines: a new classification system and their role in immunity. Immunity 2000;12:121-127. (Pubitemid 30398626)
-
(2000)
Immunity
, vol.12
, Issue.2
, pp. 121-127
-
-
Zlotnik, A.1
Yoshie, O.2
-
23
-
-
0032536869
-
Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes
-
DOI 10.1084/jem.187.6.875
-
Sallusto F, Lenig D, Mackay CR, Lanzavecchia A. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J Exp Med 1998;187:875-883. (Pubitemid 28141661)
-
(1998)
Journal of Experimental Medicine
, vol.187
, Issue.6
, pp. 875-883
-
-
Sallusto, F.1
Lenig, D.2
Mackay, C.R.3
Lanzavecchia, A.4
-
24
-
-
0032556858
-
CCR5 is characteristic of Th1 lymphocytes
-
Loetscher P, Uguccioni M, Bordoli L, et al. CCR5 is characteristic of Th1 lymphocytes. Nature 1998;391:344-345.
-
(1998)
Nature
, vol.391
, pp. 344-345
-
-
Loetscher, P.1
Uguccioni, M.2
Bordoli, L.3
-
25
-
-
0346667110
-
Structure-function relationship between the human chemokine receptor CXCR3 and its ligands
-
DOI 10.1074/jbc.M209470200
-
Clark-Lewis I, Mattioli I, Gong JH, Loetscher P. Structure-function relationship between the human chemokine receptor CXCR3 and its ligands. J Biol Chem 2003;278:289-295. (Pubitemid 36043575)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.1
, pp. 289-295
-
-
Clark-Lewis, I.1
Mattioli, I.2
Gong, J.-H.3
Loetscher, P.4
-
26
-
-
12344314536
-
Accumulation of CCR5+ T cells around RANTES+ granulomas in Crohn's disease: A pivotal site of Th1-shifted immune response?
-
Oki M, Ohtani H, Kinouchi Y, et al. Accumulation of CCR5+ T cells around RANTES+ granulomas in Crohn's disease: a pivotal site of Th1-shifted immune response? Lab Invest 2005;85:137-145.
-
(2005)
Lab Invest
, vol.85
, pp. 137-145
-
-
Oki, M.1
Ohtani, H.2
Kinouchi, Y.3
-
27
-
-
35548983907
-
Granuloma-positive Crohn's disease
-
Freeman HJ. Granuloma-positive Crohn's disease. Can J Gastroenterol 2007;21:583-587.
-
(2007)
Can J Gastroenterol
, vol.21
, pp. 583-587
-
-
Freeman, H.J.1
-
28
-
-
38549176118
-
Tumor necrosis factor antagonist mechanisms of action: A comprehensive review
-
Tracey D, Klareskog L, Sasso EH, Salfeld JG, Tak PP. Tumor necrosis factor antagonist mechanisms of action: a comprehensive review. Pharmacol Ther 2008;117:244-279.
-
(2008)
Pharmacol Ther
, vol.117
, pp. 244-279
-
-
Tracey, D.1
Klareskog, L.2
Sasso, E.H.3
Salfeld, J.G.4
Tak, P.P.5
-
29
-
-
4344694114
-
Ligands working as receptors: Reverse signaling by members of the TNF superfamily enhance the plasticity of the immune system
-
DOI 10.1016/j.cytogfr.2004.03.011, PII S135961010400022X
-
Eissner G, Kolch W, Scheurich P. Ligands working as receptors: reverse signaling by members of the TNF superfamily enhance the plasticity of the immune system. Cytokine Growth Factor Rev 2004;15:353-366. (Pubitemid 39140699)
-
(2004)
Cytokine and Growth Factor Reviews
, vol.15
, Issue.5
, pp. 353-366
-
-
Eissner, G.1
Kolch, W.2
Scheurich, P.3
-
30
-
-
14944382276
-
Infliximab induces potent anti-inflammatory responses by outside-to-inside signals through transmembrane TNF-alpha
-
DOI 10.1053/j.gastro.2004.11.060
-
Mitoma H, Horiuchi T, Hatta N, et al. Infliximab induces potent anti-inflammatory responses by outside-to-inside signals through transmembrane TNF-alpha. Gastroenterology 2005;128:376-392. (Pubitemid 40431090)
-
(2005)
Gastroenterology
, vol.128
, Issue.2
, pp. 376-392
-
-
Mitoma, H.1
Horiuchi, T.2
Hatta, N.3
Tsukamoto, H.4
Harashima, S.-I.5
Kikuchi, Y.6
Otsuka, J.7
Okamura, S.8
Fujita, S.9
Harada, M.10
-
31
-
-
2142643604
-
Control of immune pathology by regulatory T cells
-
Powrie F, Read S, Mottet C, Uhlig H, Maloy K. Control of immune pathology by regulatory T cells. Novartis Found Symp 2003;252:92-98.
-
(2003)
Novartis Found Symp
, vol.252
, pp. 92-98
-
-
Powrie, F.1
Read, S.2
Mottet, C.3
Uhlig, H.4
Maloy, K.5
-
32
-
-
0242580070
-
+ Regulatory T Cells Cure Murine Colitis: The Role of IL-10, TGF-beta, and CTLA4
-
Liu H, Hu B, Xu D, Liew FY. CD4+CD25+ regulatory T cells cure murine colitis: the role of IL-10, TGF-beta, and CTLA4. J Immunol 2003;171:5012-5017. (Pubitemid 37432781)
-
(2003)
Journal of Immunology
, vol.171
, Issue.10
, pp. 5012-5017
-
-
Liu, H.1
Hu, B.2
Xu, D.3
Liew, F.Y.4
-
33
-
-
20444434616
-
high T cells in inflammatory bowel disease
-
DOI 10.1053/j.gastro.2005.03.043, PII S0016508505005664
-
Maul J, Loddenkemper C, Mundt P, et al. Peripheral and intestinal regulatory CD4+ CD25(high) T cells in inflammatory bowel disease. Gastroenterology 2005;128:1868-1878. (Pubitemid 40824698)
-
(2005)
Gastroenterology
, vol.128
, Issue.7
, pp. 1868-1878
-
-
Maul, J.1
Loddenkemper, C.2
Mundt, P.3
Berg, E.4
Giese, T.5
Stallmach, A.6
Zeitz, M.7
Duchmann, R.8
-
34
-
-
0035180067
-
Control of intestinal inflammation by regulatory T cells
-
DOI 10.1034/j.1600-065X.2001.1820115.x
-
Singh B, Read S, Asseman C, et al. Control of intestinal inflammation by regulatory T cells. Immunol Rev 2001;182:190-200. (Pubitemid 33070218)
-
(2001)
Immunological Reviews
, vol.182
, pp. 190-200
-
-
Singh, B.1
Read, S.2
Asseman, C.3
Malmstrom, V.4
Mottet, C.5
Stephens, L.A.6
Stepankova, R.7
Tlaskalova, H.8
Powrie, F.9
-
35
-
-
37849002328
-
Basal lymphoid aggregates in ulcerative colitis colon: A site for regulatory T cell action
-
Sitohy B, Hammarström S, Danielsson A, Hammarström ML. Basal lymphoid aggregates in ulcerative colitis colon: a site for regulatory T cell action. Clin Exp Immunol 2008;151:326-333.
-
(2008)
Clin Exp Immunol
, vol.151
, pp. 326-333
-
-
Sitohy, B.1
Hammarström, S.2
Danielsson, A.3
Hammarström, M.L.4
-
36
-
-
15444363794
-
+ regulatory T cells
-
DOI 10.1084/jem.20040685
-
Fahlén L, Read S, Gorelik L, et al. T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells. J Exp Med 2005;201:737-746. (Pubitemid 40395119)
-
(2005)
Journal of Experimental Medicine
, vol.201
, Issue.5
, pp. 737-746
-
-
Fahlen, L.1
Read, S.2
Gorelik, L.3
Hurst, S.D.4
Coffman, R.L.5
Flavell, R.A.6
Powrie, F.7
|