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Volumn 5, Issue 1, 2011, Pages 37-45

Infliximab therapy impacts the peripheral immune system of immunomodulator and corticosteroid naïve patients with Crohn's disease

Author keywords

Crohn's disease; Infliximab; RANTES; Regulatory T cell; Transforming growth factor 1

Indexed keywords

CD4 ANTIBODY; CHEMOKINE; CYTOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INFLIXIMAB; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MESALAZINE; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

EID: 79952926337     PISSN: 19762283     EISSN: None     Source Type: Journal    
DOI: 10.5009/gnl.2011.5.1.37     Document Type: Article
Times cited : (25)

References (36)
  • 1
    • 0030954732 scopus 로고    scopus 로고
    • A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease
    • Crohn's Disease cA2 Study Group
    • Targan SR, Hanauer SB, van Deventer SJ, et al. A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group. N Engl J Med 1997;337:1029-1035.
    • (1997) N Engl J Med , vol.337 , pp. 1029-1035
    • Targan, S.R.1    Hanauer, S.B.2    Van Deventer, S.J.3
  • 2
    • 77950857047 scopus 로고    scopus 로고
    • Emerging biologics in the treatment of inflammatory bowel disease: What is around the corner?
    • Fiorino G, Rovida S, Correale C, Malesci A, Danese S. Emerging biologics in the treatment of inflammatory bowel disease: what is around the corner? Curr Drug Targets 2010;11:249-260.
    • (2010) Curr Drug Targets , vol.11 , pp. 249-260
    • Fiorino, G.1    Rovida, S.2    Correale, C.3    Malesci, A.4    Danese, S.5
  • 5
    • 64649100879 scopus 로고    scopus 로고
    • The expression profile of functional regulatory T cells, CD4+CD25high+/forkhead box protein P3+, in patients with ulcerative colitis during active and quiescent disease
    • Kamikozuru K, Fukunaga K, Hirota S, et al. The expression profile of functional regulatory T cells, CD4+CD25high+/forkhead box protein P3+, in patients with ulcerative colitis during active and quiescent disease. Clin Exp Immunol 2009;156:320-327.
    • (2009) Clin Exp Immunol , vol.156 , pp. 320-327
    • Kamikozuru, K.1    Fukunaga, K.2    Hirota, S.3
  • 6
    • 0002063230 scopus 로고    scopus 로고
    • A simple classification of Crohn's disease: Report of the Working Party for the World Congresses of Gastroenterology, Vienna 1998
    • Gasche C, Scholmerich J, Brynskov J, et al. A simple classification of Crohn's disease: report of the Working Party for the World Congresses of Gastroenterology, Vienna 1998. Inflamm Bowel Dis 2000;6:8-15.
    • (2000) Inflamm Bowel Dis , vol.6 , pp. 8-15
    • Gasche, C.1    Scholmerich, J.2    Brynskov, J.3
  • 8
    • 0018292706 scopus 로고
    • National cooperative Crohn's disease study: Study design and conduct of the study
    • Winship DH, Summers RW, Singleton JW, et al. National Cooperative Crohn's Disease Study: study design and conduct of the study. Gastroenterology 1979;77(4 Pt 2):829-842. (Pubitemid 9257851)
    • (1979) Gastroenterology , vol.77 , Issue.4 II , pp. 829-842
    • Winship, D.H.1    Summers, R.W.2    Singleton, J.W.3
  • 9
    • 69449091637 scopus 로고    scopus 로고
    • Modulation of the Th1/Th2 balance by infliximab improves hyperthyroidism associated with a flare-up of ulcerative colitis
    • Matsumura K, Nakase H, Yamamoto S, et al. Modulation of the Th1/Th2 balance by infliximab improves hyperthyroidism associated with a flare-up of ulcerative colitis. Inflamm Bowel Dis 2009;15:967-968.
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 967-968
    • Matsumura, K.1    Nakase, H.2    Yamamoto, S.3
  • 11
    • 70349967965 scopus 로고    scopus 로고
    • Anti-TNF biologic agents: Still the therapy of choice for rheumatoid arthritis
    • Taylor PC, Feldmann M. Anti-TNF biologic agents: still the therapy of choice for rheumatoid arthritis. Nat Rev Rheumatol 2009;5:578-582.
    • (2009) Nat Rev Rheumatol , vol.5 , pp. 578-582
    • Taylor, P.C.1    Feldmann, M.2
  • 12
    • 0031781603 scopus 로고    scopus 로고
    • Inflammatory bowel disease: Etiology and pathogenesis
    • DOI 10.1016/S0016-5085(98)70381-6
    • Fiocchi C. Inflammatory bowel disease: etiology and pathogenesis. Gastroenterology 1998;115:182-205. (Pubitemid 28307304)
    • (1998) Gastroenterology , vol.115 , Issue.1 , pp. 182-205
    • Fiocchi, C.1
  • 13
    • 44049104564 scopus 로고    scopus 로고
    • H-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat
    • DOI 10.1038/ni.1610, PII NI.1610
    • Manel N, Unutmaz D, Littman DR. The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat. Nat Immunol 2008;9:641-649. (Pubitemid 351714729)
    • (2008) Nature Immunology , vol.9 , Issue.6 , pp. 641-649
    • Manel, N.1    Unutmaz, D.2    Littman, D.R.3
  • 14
    • 33646577466 scopus 로고    scopus 로고
    • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
    • Bettelli E, Carrier Y, Gao W, et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006;441:235-238.
    • (2006) Nature , vol.441 , pp. 235-238
    • Bettelli, E.1    Carrier, Y.2    Gao, W.3
  • 16
    • 62949223226 scopus 로고    scopus 로고
    • Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression
    • Fantini MC, Rizzo A, Fina D, et al. Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression. Gastroenterology 2009;136:1308-1316, e1-e3.
    • (2009) Gastroenterology , vol.136
    • Fantini, M.C.1    Rizzo, A.2    Fina, D.3
  • 17
    • 47549112840 scopus 로고    scopus 로고
    • IL-21 and TGFbeta are required for differentiation of human T(H)17 cells
    • Yang L, Anderson DE, Baecher-Allan C, et al. IL-21 and TGFbeta are required for differentiation of human T(H)17 cells. Nature 2008;454:350-352.
    • (2008) Nature , vol.454 , pp. 350-352
    • Yang, L.1    Anderson, D.E.2    Baecher-Allan, C.3
  • 19
    • 0037013930 scopus 로고    scopus 로고
    • Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation
    • DOI 10.1084/jem.20012076
    • Gorelik L, Constant S, Flavell RA. Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation. J Exp Med 2002;195:1499-1505. (Pubitemid 34602827)
    • (2002) Journal of Experimental Medicine , vol.195 , Issue.11 , pp. 1499-1505
    • Gorelik, L.1    Constant, S.2    Flavell, R.A.3
  • 21
    • 70149087732 scopus 로고    scopus 로고
    • Diminution of Circulating CD4+CD25 high T cells in naïve Crohn's disease
    • Chamouard P, Monneaux F, Richert Z, et al. Diminution of Circulating CD4+CD25 high T cells in naïve Crohn's disease. Dig Dis Sci 2009;54:2084-2093.
    • (2009) Dig Dis Sci , vol.54 , pp. 2084-2093
    • Chamouard, P.1    Monneaux, F.2    Richert, Z.3
  • 22
    • 0034144269 scopus 로고    scopus 로고
    • Chemokines: A new classification system and their role in immunity
    • Zlotnik A, Yoshie O. Chemokines: a new classification system and their role in immunity. Immunity 2000;12:121-127. (Pubitemid 30398626)
    • (2000) Immunity , vol.12 , Issue.2 , pp. 121-127
    • Zlotnik, A.1    Yoshie, O.2
  • 23
    • 0032536869 scopus 로고    scopus 로고
    • Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes
    • DOI 10.1084/jem.187.6.875
    • Sallusto F, Lenig D, Mackay CR, Lanzavecchia A. Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J Exp Med 1998;187:875-883. (Pubitemid 28141661)
    • (1998) Journal of Experimental Medicine , vol.187 , Issue.6 , pp. 875-883
    • Sallusto, F.1    Lenig, D.2    Mackay, C.R.3    Lanzavecchia, A.4
  • 24
    • 0032556858 scopus 로고    scopus 로고
    • CCR5 is characteristic of Th1 lymphocytes
    • Loetscher P, Uguccioni M, Bordoli L, et al. CCR5 is characteristic of Th1 lymphocytes. Nature 1998;391:344-345.
    • (1998) Nature , vol.391 , pp. 344-345
    • Loetscher, P.1    Uguccioni, M.2    Bordoli, L.3
  • 25
    • 0346667110 scopus 로고    scopus 로고
    • Structure-function relationship between the human chemokine receptor CXCR3 and its ligands
    • DOI 10.1074/jbc.M209470200
    • Clark-Lewis I, Mattioli I, Gong JH, Loetscher P. Structure-function relationship between the human chemokine receptor CXCR3 and its ligands. J Biol Chem 2003;278:289-295. (Pubitemid 36043575)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.1 , pp. 289-295
    • Clark-Lewis, I.1    Mattioli, I.2    Gong, J.-H.3    Loetscher, P.4
  • 26
    • 12344314536 scopus 로고    scopus 로고
    • Accumulation of CCR5+ T cells around RANTES+ granulomas in Crohn's disease: A pivotal site of Th1-shifted immune response?
    • Oki M, Ohtani H, Kinouchi Y, et al. Accumulation of CCR5+ T cells around RANTES+ granulomas in Crohn's disease: a pivotal site of Th1-shifted immune response? Lab Invest 2005;85:137-145.
    • (2005) Lab Invest , vol.85 , pp. 137-145
    • Oki, M.1    Ohtani, H.2    Kinouchi, Y.3
  • 27
    • 35548983907 scopus 로고    scopus 로고
    • Granuloma-positive Crohn's disease
    • Freeman HJ. Granuloma-positive Crohn's disease. Can J Gastroenterol 2007;21:583-587.
    • (2007) Can J Gastroenterol , vol.21 , pp. 583-587
    • Freeman, H.J.1
  • 28
    • 38549176118 scopus 로고    scopus 로고
    • Tumor necrosis factor antagonist mechanisms of action: A comprehensive review
    • Tracey D, Klareskog L, Sasso EH, Salfeld JG, Tak PP. Tumor necrosis factor antagonist mechanisms of action: a comprehensive review. Pharmacol Ther 2008;117:244-279.
    • (2008) Pharmacol Ther , vol.117 , pp. 244-279
    • Tracey, D.1    Klareskog, L.2    Sasso, E.H.3    Salfeld, J.G.4    Tak, P.P.5
  • 29
    • 4344694114 scopus 로고    scopus 로고
    • Ligands working as receptors: Reverse signaling by members of the TNF superfamily enhance the plasticity of the immune system
    • DOI 10.1016/j.cytogfr.2004.03.011, PII S135961010400022X
    • Eissner G, Kolch W, Scheurich P. Ligands working as receptors: reverse signaling by members of the TNF superfamily enhance the plasticity of the immune system. Cytokine Growth Factor Rev 2004;15:353-366. (Pubitemid 39140699)
    • (2004) Cytokine and Growth Factor Reviews , vol.15 , Issue.5 , pp. 353-366
    • Eissner, G.1    Kolch, W.2    Scheurich, P.3
  • 32
    • 0242580070 scopus 로고    scopus 로고
    • + Regulatory T Cells Cure Murine Colitis: The Role of IL-10, TGF-beta, and CTLA4
    • Liu H, Hu B, Xu D, Liew FY. CD4+CD25+ regulatory T cells cure murine colitis: the role of IL-10, TGF-beta, and CTLA4. J Immunol 2003;171:5012-5017. (Pubitemid 37432781)
    • (2003) Journal of Immunology , vol.171 , Issue.10 , pp. 5012-5017
    • Liu, H.1    Hu, B.2    Xu, D.3    Liew, F.Y.4
  • 35
    • 37849002328 scopus 로고    scopus 로고
    • Basal lymphoid aggregates in ulcerative colitis colon: A site for regulatory T cell action
    • Sitohy B, Hammarström S, Danielsson A, Hammarström ML. Basal lymphoid aggregates in ulcerative colitis colon: a site for regulatory T cell action. Clin Exp Immunol 2008;151:326-333.
    • (2008) Clin Exp Immunol , vol.151 , pp. 326-333
    • Sitohy, B.1    Hammarström, S.2    Danielsson, A.3    Hammarström, M.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.