Modulation of the Th1/Th2 balance by infliximab improves hyperthyroidism associated with a flareup of ulcerative colitis

Inflammatory Bowel Diseases

Volumn 15, Issue 7, 2009, Pages 967-968

  Matsumura, Kayoto ^a   Nakase, Hiroshi ^a   Yamamoto, Shuji ^a   Yoshino, Takuya ^a   Takeda, Yasuhiro ^a   Kasahara, Katsuhiro ^a   Ueno, Satoru ^a   Uza, Norimitsu ^a   Chiba, Tsutomu ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; INFLIXIMAB; LIOTHYRONINE; MESALAZINE; PROBIOTIC AGENT; SALAZOSULFAPYRIDINE; TACROLIMUS; THYROTROPIN; THYROXINE; ANTIINFLAMMATORY AGENT; MONOCLONAL ANTIBODY;

ABDOMINAL TENDERNESS; ADULT; BLOODY DIARRHEA; CASE REPORT; CD4+ T LYMPHOCYTE; COLONOSCOPY; DISEASE ACTIVITY; DISEASE ASSOCIATION; DISEASE EXACERBATION; FEMALE; FEVER; FREE LIOTHYRONINE INDEX; FREE THYROXINE INDEX; HEART PALPITATION; HUMAN; HYPERTHYROIDISM; INTESTINE ULCER; LETTER; LEUKAPHERESIS; MALNUTRITION; PRIORITY JOURNAL; RECURRENT DISEASE; REMISSION; TH1 CELL; TH2 CELL; THYROID FUNCTION; ULCERATIVE COLITIS; UNSPECIFIED SIDE EFFECT; DRUG EFFECT; IMMUNOLOGY;

ADULT; ANTI-INFLAMMATORY AGENTS; ANTIBODIES, MONOCLONAL; COLITIS, ULCERATIVE; FEMALE; HUMANS; HYPERTHYROIDISM; TH1 CELLS; TH2 CELLS;

EID: 69449091637     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1002/ibd.20760     Document Type: Letter

References (8)

1. Snook JA, de Silva HJ, Jewell DP. The association of autoimmune disorders with inflammatory bowel disease. Q J Med. 1989;72:835-840.
2. Jarnerot G, Azad Khan AK, Truelove SC. The thyroid in ulcerative colitis and Crohn's disease. II. Thyroid enlargement and hyperthyroidism in ulcerative colitis. Acta Med Scand. 1975;197:83-87.
3. Triantafillidis JK, Cherakakis P, Zervakakis A, et al. Coexistence of hyperthyroidism and ulcerative colitis: report of 4 cases and a review of the literature. Ital J Gastroenterol. 1992;24:494-497.
4. Powell JR, Shapiro HA, Carbone JV. Therapeutic problems of ulcerative colitis with hyperthyroidism. Am J Gastroenterol. 1968;50: 116-124.
5. Kallmann BA, Hüther M, Tubes M, et al. Systemic bias of cytokine production toward cell-mediated immune regulation in IDDM and toward humoral immunity in Graves' disease. Diabetes. 1997;46:237-243.
6. Komorowski J, Jankiewicz-Wika J, Siejka A. Monoclonal anti-TNF alpha antibody (infliximab) in the treatment of patient with thyroid associated ophthalmopathy. Klin Oczna. 2007;109:457-460.
7. Bahn RS. Understanding the immunology of Graves' ophthalmopathy. Is it an autoimmune disease? Review. Endocrinol Metab Clin North Am. 2000;29:287-296, vi.
8. Diez JJ, Hernanz A, Medina S,et al. Serum concentrations of tumour necrosis factor-alpha (TNF-alpha) and soluble TNF-alpha receptor p55 in patients with hypothyroidism and hyperthyroidism before and after normalization of thyroid function. Clin Endocrinol (Oxf). 2002;57:515-521.