Effects of risk genes on BOLD activation in presymptomatic carriers of familial alzheimer's disease mutations during a novelty encoding task

Cerebral Cortex

Volumn 21, Issue 4, 2011, Pages 877-883

  Ringman, John M ^a   Medina, Luis D ^a   Braskie, Meredith ^a,d   Rodriguez Agudelo, Yaneth ^b   Geschwind, Daniel H ^a   MacIas Islas, Miguel A ^c   Cummings, Jeffrey L ^a   Bookheimer, Susan ^d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NATIONAL INSTITUTE OF NEUROLOGY AND NEUROSURGERY   (Mexico)

^c UNIVERSITY OF GUADALAJARA   (Mexico)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Alzheimer's disease; apolipoprotein E; familial; functional magnetic resonance imaging; presymptomatic

Indexed keywords

APOLIPOPROTEIN E; OXYGEN;

ADULT; ALZHEIMER DISEASE; ANTERIOR CINGULATE; ARTICLE; BOLD SIGNAL; CLINICAL ARTICLE; FAMILIAL DISEASE; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GENE MUTATION; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; HETEROZYGOTE; HUMAN; MALE; MEXICO; OCCIPITAL CORTEX; PRIORITY JOURNAL; SUPRASYLVIAN GYRUS; WESTERN HEMISPHERE;

ADULT; ALZHEIMER DISEASE; APOLIPOPROTEIN E3; BRAIN MAPPING; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HETEROZYGOTE; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MEXICAN AMERICANS; MEXICO; MUTATION; NEUROPSYCHOLOGICAL TESTS; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RISK FACTORS; YOUNG ADULT;

EID: 79952830370     PISSN: 10473211     EISSN: 14602199     Source Type: Journal    
DOI: 10.1093/cercor/bhq158     Document Type: Article

References (42)

1. Artiola-i-Fortuny L, Hermosillo D, Heaton RK, Pardee RE. 1999. Manual de Normal y Procedimientos para la Bateria Neuropsiclogia en Espanol. Tucson (AZ): Neuropsychology Press.
2. Bassett SS, Yousem DM, Cristinzio C, Kusevic I, Yassa MA, Caffo BS, Zeger SL. 2006. Familial risk for Alzheimer's disease alters fMRI activation patterns. Brain. 129:1229-1239.
3. Bondi MW, Houston WS, Eyler LT, Brown GG. 2005. fMRI evidence of compensatory mechanisms in older adults at genetic risk for Alzheimer disease. Neurology. 64:501-508. (Pubitemid 40189870)
4. Bookheimer SY, Magdalena H, Strojwas BS, Cohen MS, Saunders AM, Pericak-Vance MA, Mazziotta JC, Small GW. 2000. Patterns of brain activation in people at risk for Alzheimer's disease. N Engl J Med. 343:450-456. (Pubitemid 30646483)
5. Corder EH, Saunders AM, Strittmatter WJ, Schmechel DE, Gaskell PC, Small GW, Roses AD, Haines JL, Pericak-Vance MA. 1993. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science. 261:921-923. (Pubitemid 23275809)
6. Cummings JL. 1995. Anatomic and behavioral aspects of frontal-subcortical circuits. Ann N Y Acad Sci. 769:1-13. (Pubitemid 26075880)
7. DeCarli C, Reed BR, Jagust W, Martinez O, Ortega M, Mungas D. 2008. Brain behavior relationships among African Americans, Whites, and Hispanics. Alzheimer Dis Assoc Disord. 22:382-391.
8. Dickerson BC, Salat DH, Bates JF, Atiya M, Killiany RJ, Greve DN, Dale AM, Stern CE, Blacker D, Albert MS, et al. 2004. Medial temporal lobe function and structure in mild cognitive impairment. Ann Neurol. 56:27-35. (Pubitemid 38857357)
9. Evans AC, Marrett S, Neelin P, Collins L, Worsley K, Dai W, Milot S, Meyer E, Bub D. 1992. Anatomical mapping of functional activation in stereotactic coordinate space. Neuroimage. 1:43-53.
10. Filippini N, MacIntosh BJ, Hough MG, Goodwin GM, Frisoni GB, Smith SM, Matthews PM, Beckmann CF, Mackay CE. 2009. Distinct patterns of brain activity in young carriers of the APOE-epsilon4 allele. Proc Natl Acad Sci USA. 106:7209-7214.
11. Fleisher AS, Houston WS, Eyler LT, Frye S, Jenkins C, Thal LJ, Bondi MW. 2005. Identification of Alzheimer disease risk by functional magnetic resonance imaging. Arch Neurol. 62:1881-1888. (Pubitemid 41785082)
12. Fox NC, Kennedy AM, Harvey RJ, Lantos PL, Roques PK, Collinge J, Hardy J, Hutton M, Stevens JM, Warrington EK, et al. 1997. Clinico-pathological features of familial Alzheimer's disease associated with the M139V mutation in the presenilin 1 gene. Pedigree but not mutation specific age at onset provides evidence for a further genetic factor. Brain. 120:491-501. (Pubitemid 27153641)
13. Jenkinson M, Smith S. 2001. A global optimisation method for robust affine registration of brain images. Med Image Anal. 5:143-156. (Pubitemid 35282800)
14. Johnson KA, Lopera F, Jones K, Becker A, Sperling R, Hilson J, Londono J, Siegert I, Arcos M, Moreno S, et al. 2001. Presenilin-1-associated abnormalities in regional cerebral perfusion. Neurology. 56:1545-1551. (Pubitemid 32532268)
15. Johnson SC, Schmitz TW, Trivedi MA, Ries ML, Torgerson BM, Carlsson CM, Asthana S, Hermann BP, Sager MA. 2006. The influence of Alzheimer disease family history and apolipoprotein E epsilon4 on mesial temporal lobe activation. J Neurosci. 26:6069-6076. (Pubitemid 44334754)
16. Klunk WE, Price JC, Mathis CA, Tsopelas ND, Lopresti BJ, Ziolko SK, Bi W, Hoge JA, Cohen AD, Ikonomovic MD, et al. 2007. Amyloid deposition begins in the striatum of presenilin-1 mutation carriers from two unrelated pedigrees. J Neurosci. 27:6174-6184. (Pubitemid 46890033)
17. Koivunen J, Verkkoniemi A, Aalto S, Paetau A, Ahonen JP, Viitanen M, Nagren K, Rokka J, Haaparanta M, Kalimo H, et al. 2008. PET amyloid ligand [11C]PIB uptake shows predominantly striatal increase in variant Alzheimer's disease. Brain. 131:1845-1853. (Pubitemid 351957460)
18. Li C, Zheng J, Wang J, Gui L, Li C. 2009. An FMRI stroop task study of prefrontal cortical function in normal aging, mild cognitive impairment, and Alzheimer's disease. Curr Alzheimer Res. 6(6):525-530.
19. Lind J, Persson J, Ingvar M, Larsson A, Cruts M, Van Broeckhoven C, Adolfsson R, Backman L, Nilsson LG, Petersson KM, et al. 2006. Reduced functional brain activity response in cognitively intact apolipoprotein E epsilon4 carriers. Brain. 129:1240-1248.
20. Loewenstein DA, Rubert MP, Arguelles T, Duara R. 1995. Neuro-psychological test performance and prediction of functional capacities among Spanish-speaking and English-speaking patients with dementia. Arch Clin Neuropsychol. 10:75-88.
21. Mattsson N, Zetterberg H, Hansson O, Andreasen N, Parnetti L, Jonsson M, Herukka SK, Van der Flier WM, Blankenstein MA, Ewers M, et al. 2009. CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment. JAMA. 302:385-393.
22. Mondadori CR, Buchmann A, Mustovic H, Schmidt CF, Boesiger P, Nitsch RM, Hock C, Streffer J, Henke K. 2006. Enhanced brain activity may precede the diagnosis of Alzheimer's disease by 30 years. Brain. 129:2908-2922. (Pubitemid 44684512)
23. Morris JC. 1997. Clinical dementia rating: a reliable and valid diagnostic and staging measure for dementia of the Alzheimer type. Int Psychogeriatr. 9(Suppl 1):173-176; discussion 177-178. (Pubitemid 28045357)
24. Mullan M, Tsuji S, Miki T, Katsuya T, Naruse S, Kaneko K, Shimizu T, Kojima T, Nakano I, Ogihara T, et al. 1993. Clinical comparison of Alzheimer's disease in pedigrees with the codon 717 Val/Ile mutation in the amyloid precursor protein gene. Neurobiol Aging. 14:407-419. (Pubitemid 23270005)
25. Mungas D, Reed BR, Crane PK, Haan MN, Gonzalez H. 2004. Spanish and English Neuropsychological Assessment Scales (SENAS): further development and psychometric characteristics. Psychol Assess. 16:347-359. (Pubitemid 39546413)
26. Mungas D, Reed BR, Farias ST, Decarli C. 2009. Age and education effects on relationships of cognitive test scores with brain structure in demographically diverse older persons. Psychol Aging. 24:116-128.
27. Murrell J, Ghetti B, Cochran E, Macias-Islas MA, Medina L, Varpetian A, Cummings JL, Mendez MF, Kawas C, Chui H, et al. 2006. The A431E mutation in PSEN1 causing familial Alzheimer's disease originating in Jalisco State, Mexico: an additional fifteen families. Neurogenetics. 7:277-279. (Pubitemid 44584082)
28. Okello A, Koivunen J, Edison P, Archer HA, Turkheimer FE, Nagren K, Bullock R, Walker Z, Kennedy A, Fox NC, et al. 2009. Conversion of amyloid positive and negative MCI to AD over 3 years: an 11C-PIB PET study. Neurology. 73:754-760.
29. Ringman JM, Medina LD, Rodriguez-Agudelo Y, Chavez M, Lu P, Cummings JL. 2009. Current concepts of mild cognitive impairment and their applicability to persons at-risk for familial Alzheimer's disease. Curr Alzheimer Res. 6:341-346.
30. Seeley WW, Menon V, Schatzberg AF, Keller J, Glover GH, Kenna H, Reiss AL, Greicius MD. 2007. Dissociable intrinsic connectivity networks for salience processing and executive control. J Neurosci. 27:2349-2356. (Pubitemid 46340968)
31. Smith SM. 2002. Fast robust automated brain extraction. Hum Brain Mapp. 17:143-155. (Pubitemid 35253488)
32. Smith SM, Zhang Y, Jenkinson M, Chen J, Matthews PM, Federico A, De Stefano N. 2002. Accurate, robust, and automated longitudinal and cross-sectional brain change analysis. Neuroimage. 17:479-489.
33. Stern CE, Corkin S, Gonzalez RG, Guimaraes AR, Baker JR, Jennings PJ, Carr CA, Sugiura RM, Vedantham V, Rosen BR. 1996. The hippocampal formation participates in novel picture encoding: evidence from functional magnetic resonance imaging. Proc Natl Acad Sci USA. 93:8660-8665. (Pubitemid 26269616)
34. Stroop JR. 1935. Studies of interference in serial verbal reactions. J Exp Psychol. 8:643-662.
35. Teng EL, Hasegawa K, Homma A, Imai Y, Larson E, Graves A, Sugimoto K, Yamaguchi T, Sasaki H, Chiu D, et al. 1994. The Cognitive Abilities Screening Instrument (CASI): a practical test for cross-cultural epidemiological studies of dementia. Int Psychoger-iatr. 6:45-58; discussion 62. (Pubitemid 24167129)
36. Troncoso JC, Cataldo AM, Nixon RA, Barnett JL, Lee MK, Checler F, Fowler DR, Smialek JE, Crain B, Martin LJ, et al. 1998. Neuropathol-ogy of preclinical and clinical late-onset Alzheimer's disease. Ann Neurol. 43:673-676. (Pubitemid 28225562)
37. Wechsler D. 1987. Wechsler Memory Scale-Revised manual. San Antonio (CA): Psychological Corporation.
38. Woolrich MW, Behrens TE, Beckmann CF, Jenkinson M, Smith SM. 2004. Multilevel linear modelling for FMRI group analysis using Bayesian inference. Neuroimage. 21:1732-1747. (Pubitemid 38446594)
39. Woolrich MW, Ripley BD, Brady M, Smith SM. 2001. Temporal autocorrelation in univariate linear modeling of FMRI data. Neuro-image. 14:1370-1386. (Pubitemid 33124185)
40. Worsley KJ, Evans AC, Marrett S, Neelin P. 1992. A three-dimensional statistical analysis for CBF activation studies in human brain. J Cereb Blood Flow Metab. 12:900-918.
41. Yassa MA, Verduzco G, Cristinzio C, Bassett SS. 2008. Altered fMRI activation during mental rotation in those at genetic risk for Alzheimer disease. Neurology. 70:1898-1904. (Pubitemid 351684643)
42. Yescas P, Huertas-Vazquez A, Villarreal-Molina MT, Rasmussen A, Tusie-Luna MT, Lopez M, Canizales-Quinteros S, Alonso ME. 2006. Founder effect for the Ala431Glu mutation of the presenilin 1 gene causing early-onset Alzheimer's disease in Mexican families. Neurogenetics. 7:195-200. (Pubitemid 44078297)