Molecular mechanism of substrate specificity in the bacterial neutral amino acid transporter LeuT

Proteins: Structure, Function and Genetics

Volumn 73, Issue 4, 2008, Pages 851-863

  Noskov, Sergei Y ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

Free energy simulations; NSS transporters; Substrate specificity

Indexed keywords

ALANINE; AMINO ACID TRANSPORTER; AMPHOLYTE; GLYCINE; LEUCINE; LEUT PROTEIN; NEUROTRANSMITTER TRANSPORTER; UNCLASSIFIED DRUG; WATER; AMINO ACID; LIGAND;

ARTICLE; BACTERIUM; BINDING SITE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; DECOMPOSITION; ENERGY TRANSFER; ENZYME SPECIFICITY; HYDRATION; HYDROGEN BOND; LIGAND BINDING; MEMBRANE TRANSPORT; MOLECULAR DYNAMICS; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN BINDING; X RAY CRYSTALLOGRAPHY; CHEMICAL STRUCTURE; COMPUTER SIMULATION; GENETICS; METABOLISM; MUTATION; PROTEIN SECONDARY STRUCTURE; PROTON MOTIVE FORCE; THERMODYNAMICS;

BACTERIA (MICROORGANISMS);

AMINO ACID TRANSPORT SYSTEMS, NEUTRAL; AMINO ACIDS; BACTERIA; BINDING SITES; COMPUTER SIMULATION; LIGANDS; MODELS, MOLECULAR; MUTATION; PROTEIN STRUCTURE, SECONDARY; PROTON-MOTIVE FORCE; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

EID: 58149311441     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.22108     Document Type: Article

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