Biological activity of three novel complexes with the ligand 5-methyl-1,2,4-triazolo[1,5-a]pyrimidin-7(4H)-one against Leishmania spp

Journal of Antimicrobial Chemotherapy

Volumn 66, Issue 4, 2011, Pages 813-819

  Ramírez Macías, Inmaculada ^a   Marín, Clotilde ^a   Salas, Juan Manuel ^a   Caballero, Ana ^a   Rosales, María José ^a   Villegas, Noelia ^a   Rodríguez Dieguez, Antonio ^a   Barea, Elisa ^a   Sánchez Moreno, Manuel ^a  

^a UNIVERSITY OF GRANADA   (Spain)

Author keywords

Leishmania braziliensis; Leishmania infantum; Leishmaniasis; Triazolopyrimidines

Indexed keywords

5 METHYL 1,2,4 TRIAZOLO[1,5 A]PYRIMIDIN 7(4H) ONE DERIVATIVE; ANTILEISHMANIAL AGENT; LIGAND; MEGLUMINE ANTIMONATE; NICOTINAMIDE ADENINE DINUCLEOTIDE; PYRIMIDINE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; UNCLASSIFIED DRUG;

AMASTIGOTE; ANIMAL CELL; ANTIPROTOZOAL ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CELL DEATH; CELL ORGANELLE; CELL PROLIFERATION; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEGRADATION; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; ENERGY METABOLISM; FEMALE; IC 50; IN VITRO STUDY; LEISHMANIA BRAZILIENSIS; LEISHMANIA INFANTUM; MACROPHAGE; NONHUMAN; RAT; ULTRASTRUCTURE;

ANTIPROTOZOAL AGENTS; CELL SURVIVAL; INHIBITORY CONCENTRATION 50; LEISHMANIA BRAZILIENSIS; LEISHMANIA INFANTUM; ORGANELLES; PARASITIC SENSITIVITY TESTS; PYRIMIDINES; TRIAZOLES;

EID: 79952776944     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkq537     Document Type: Article

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