Unusual activity pattern of leucine aminopeptidase inhibitors based on phosphorus containing derivatives of methionine and norleucine

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 26, Issue 2, 2011, Pages 155-161

  Pícha, Jan ^a   Liboska, Radek ^a   Budìšínský, Miloš ^a   Jiráèek, Jiøi ^a   Pawełczak, Małgorzata ^b   Mucha, Artur ^c  

^a INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

^b UNIVERSITY OF OPOLE   (Poland)

^c WROCLAW UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

aminophosphinates; Aminophosphonates; cytosolic leucine aminopeptidase; inhibitors; methionine; norleucine; phosphorus containing dipeptides

Indexed keywords

1 AMINO 3 (METHYLSULPHANYL)PROPYL PHOSPHINIC ACID; 1 AMINO 3 (METHYLSULPHANYL)PROPYL PHOSPHONIC ACID; 1 AMINOPENTYL PHOSPHINIC ACID; 3 [1 AMINO 3 (METHYLSULPHANYL)PROPYL](HYDROXY)PHOSPHINYL 2 METHYL PROPANOIC ACID; LEUCINE; METHIONINE; NORLEUCINE; PHENYLALANINE; PHOSPHINIC ACID DERIVATIVE; PHOSPHONIC ACID DERIVATIVE; PHOSPHORIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG SYNTHESIS; ENZYME ISOLATION; ENZYME PURIFICATION; FOURIER TRANSFORM MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION;

ANIMALS; ENZYME ACTIVATION; ENZYME INHIBITORS; KIDNEY; LEUCYL AMINOPEPTIDASE; METHIONINE; MOLECULAR STRUCTURE; NORLEUCINE; PHOSPHORUS; SWINE;

SUS;

EID: 79952757853     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756366.2010.482047     Document Type: Article

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