Computer-aided design and activity prediction of leucine aminopeptidase inhibitors

Journal of Computer-Aided Molecular Design

Volumn 14, Issue 6, 2000, Pages 531-544

  Grembecka, J ^a   Sokalski, W A ^a   Kafarski, P ^a  

^a WROCLAW UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

Activity prediction; Drug design; Leucine aminopeptidase (LAP); Ligand receptor interactions; LUDI; Phosphonic acid inhibitors

Indexed keywords

AMINO ACIDS; COMPUTER AIDED DESIGN; CRYSTAL STRUCTURE; ENZYMES; FORECASTING; LIGANDS;

ACID INHIBITOR; ACTIVITY PREDICTIONS; COMPUTER-AIDED DESIGN; DRUG DESIGN; LEUCINE AMINOPEPTIDASE; LIGAND-RECEPTOR INTERACTIONS; LUDI; PHOSPHONIC ACID INHIBITOR; PHOSPHONIC ACIDS;

BINDING ENERGY;

CYTOSOL AMINOPEPTIDASE; ENZYME INHIBITOR; INH 686; INH 692; INH 693; INH 742; INH 761; INH 780; INH 785; INH 794; INH 856; PHOSPHONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CHEMICAL INTERACTION; COMPLEX FORMATION; COMPUTER AIDED DESIGN; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG ACTIVITY; DRUG DESIGN; DRUG STRUCTURE; ENZYME ACTIVE SITE; HYDROGEN BOND; NONHUMAN; PREDICTION; PRIORITY JOURNAL;

EID: 0033921051     PISSN: 0920654X     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1008189716955     Document Type: Article

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