Microvascular patterning is controlled by fine-tuning the Akt signal

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 1, 2005, Pages 128-133

  Jing, Fang Sun ^a   Phung, Thuy ^a   Shiojima, Ichiro ^b   Felske, Terri ^a   Upalakalin, J Nalinee ^a   Feng, Dian ^a   Kornaga, Tad ^a   Dor, Talia ^a   Dvorak, Ann M ^a   Walsh, Kenneth ^b   Benjamin, Laura E ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BOSTON UNIVERSITY   (United States)

Author keywords

Akt PKB; Angiogenesis; Retina

Indexed keywords

PROTEIN KINASE B;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONGENITAL BLOOD VESSEL MALFORMATION; CONTROLLED STUDY; EDEMA; EMBRYO; EMBRYO DEATH; ENZYME ACTIVITY; FEMALE; GENE OVEREXPRESSION; MICROVASCULATURE; MOUSE; NEWBORN; NONHUMAN; OCULAR BLOOD VESSEL; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; VASCULARIZATION;

ANIMALS; IMMUNOHISTOCHEMISTRY; MICE; MICE, TRANSGENIC; NEOVASCULARIZATION, PATHOLOGIC; NEOVASCULARIZATION, PHYSIOLOGIC; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RETINAL VESSELS; RNA, MESSENGER; SIGNAL TRANSDUCTION; SKIN;

ANIMALIA;

EID: 19944426515     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0403198102     Document Type: Article

References (38)

1. Dimmeler, S. & Zeiher, A. M. (2000) Circ. Res. 87, 434-439.
2. Liu, W., Ahmad, S. A., Reinmuth, N., Shaheen, R. M., Jung, Y. D., Fan, F. & Ellis, L. M. (2000) Apoptosis 5, 323-328.
3. Stone, J., Itin, A., Alon, T., Pe'er, J., Gnessin, H., Chan-Ling, T. & Keshet, E. (1995) J. Neurosci. 15, 4738-4747.
4. Provis, J. M., Leech, J., Diaz, C. M., Penfold, P. L., Stone, J. & Keshet, E. (1997) Exp. Eye Res. 65, 555-568.
5. Pe'er, J., Shweiki, D., Itin, A., Hemo, I., Gnessin, H. & Keshet, E. (1995) Lab. Invest. 72, 638-645.
6. Aiello, L. P. & Wong, J. S. (2000) Kidney Int. Suppl. 77, S113-S119.
7. Miller, J. W. (1997) Am. J. Pathol. 151, 13-23.
8. Alon, T., Hemo, I., Itin, A., Pe'er, J., Stone, J. & Keshet, E. (1995) Nat. Med. 1, 1024-1028.
9. Gerhardt, H., Golding, M., Fruttiger, M., Ruhrberg, C., Lundkvist, A., Abramsson, A., Jeltsch, M., Mitchell, C., Alitalo, K., Shima, D. & Betsholtz, C. (2003) J. Cell Biol. 161, 1163-1177.
10. Shweiki, D., Itin, A., Soffer, D. & Keshet, E. (1992) Nature 359, 843-845.
11. Stone, J., Chan Ling, T., Pe'er, J., Itin, A., Gnessin, H. & Keshet, E. (1996) Invest. Ophthalmol. Vis. Sci. 37, 290-299.
12. Orlidge, A. & D'Amore, P. A. (1987) J. Cell Biol. 105, 1455-1462.
13. Benjamin, L. E., Hemo, I. & Keshet, E. (1998) Development (Cambridge, U.K.) 125, 1591-1598.
14. Ishida, S., Yamashiro, K., Usui, T., Kaji, Y., Ogura, Y., Hida, T., Honda, Y., Oguchi, Y. & Adamis, A. P. (2003) Nat. Med. 9, 781-788.
15. Shiojima, I. & Walsh, K. (2002) Circ. Res. 90, 1243-1250.
16. Franke, T. F., Hornik, C. P., Segev, L., Shostak, G. A. & Sugimoto, C. (2003) Oncogene 22, 8983-8998.
17. Pierce, E. A., Foley, E. D. & Smith, L. E. (1996) Arch. Ophthalmol. 114, 1219-1228.
18. Smith, L. E., Wesolowski, E., McLellan, A., Kostyk, S. K., D'Amato, R., Sullivan, R. & D'Amore, P. A. (1994) Invest. Ophthalmol. Vis. Sci. 35, 101-111.
19. Shweiki, D., Neeman, M., Itin, A. & Keshet, E. (1995) Proc. Natl. Acad. Sci. USA 92, 768-772.
20. Forsythe, J. A., Jiang, B. H., Iyer, N. V., Agani, F., Leung, S. W., Koos, R. D. & Semenza, G. L. (1996) Mol. Cell. Biol. 16, 4604-4613.
21. Stein, I., Itin, A., Einat, P., Skaliter, R., Grossman, Z. & Keshet, E. (1998) Mol. Cell. Biol. 18, 3112-3119.
22. Smith, L. E., Shen, W., Perruzzi, C., Soker, S., Kinose, F., Xu, X., Robinson, G., Driver, S., Bischoff, J., Zhang, B., et al. (1999) Nat. Med. 5, 1390-1395.
23. Upalakalin, J. N., Hemo, I., Dehio, C., Keshet, E. & Benjamin, L. E. (2002) Cold Spring Harbor Symp. Quant. Biol. 67, 181-187.
24. Shih, S. C., Ju, M., Liu, N. & Smith, L. E. (2003) J. Clin. Invest. 112, 50-57.
25. Dor, Y., Porat, R. & Keshet, E. (2001) Am. J. Physiol. 280, C1367-C1374.
26. Benjamin, L. E., Golijanin, D., Itin, A., Pode, D. & Keshet, E. (1999) J. Clin. Invest. 103, 159-165.
27. Hackett, S. F., Wiegand, S., Yancopoulos, G. & Campochiaro, P. A. (2002) J. Cell Physiol. 192, 182-187.
28. Gale, N., Thurston, G., Hackett, S., Renard, R., Wang, Q., McClain, J., Martin, C., Witte, C., Witte, M., Jackson, D., et al. (2002) Dev. Cell 3, 411-423.
29. Fujikawa, K., de Aos Scherpenseel, I., Jain, S. K., Presman, E., Christensen, R. A. & Varticovski, L. (1999) Exp. Cell Res. 253, 663-672.
30. Papapetropoulos, A., Fulton, D., Mahboubi, K., Kalb, R. G., O'Connor, D. S., Li, F., Altieri, D. C. & Sessa, W. C. (2000) J. Biol. Chem. 275, 9102-9105.
31. Kim, I., Kim, H. G., So, J. N., Kim, J. H., Kwak, H. J. & Koh, G. Y. (2000) Circ. Res. 86, 24-29.
32. Kim, I., Kim, J. H., Moon, S. O., Kwak, H. J., Kim, N. G. * Koh, G. Y. (2000) Oncogene 19, 4549-4552.
33. Hatva, E., Jaaskelainen, J., Hirvonen, H., Alitalo, K. & Haltia, M. (1996) J. Neuropathol. Exp. Neurol. 55, 1124-1133.
34. Hashimoto, T., Lam, T., Boudreau, N. J., Bollen, A. W., Lawton, M. T. & Young, W. L. (2001) Circ. Res. 89, 111-113.
35. Vikkula, M., Boon, L. M., Carraway, K. L., III, Calvert, J. T., Diamonti, A. J., Goumnerov, B., Pasyk, K. A., Marchuk, D. A., Warman, M. L., Cantley, L. C., et al. (1996) Cell 87, 1181-1190.
36. Korpelainen, E. I., Karkkainen, M., Gunji, Y., Vikkula, M. & Alitalo, K. (1999) Oncogene 18, 1-8.
37. Niu, Q., Perruzzi, C., Voskas, D., Lawler, J., Dumont, D. J. & Benjamin, L. E. (2004) Cancer Biol. Ther. 3, 402-405.
38. Gory, S., Vernet, M., Laurent, M., Dejana, E., Dalmon, J. & Huber, P. (1999) Blood 93, 184-192.