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Volumn 108, Issue 10, 2011, Pages 4093-4098

Wounding mobilizes hair follicle stem cells to form tumors

Author keywords

Carcinogenesis; Reepithelialization; Skin cancer; Wound healing

Indexed keywords

SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN;

EID: 79952741709     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1013098108     Document Type: Article
Times cited : (100)

References (51)
  • 1
    • 0041784078 scopus 로고    scopus 로고
    • Wound epithelialization: Accelerating the pace of discovery
    • Coulombe P-A (2003) Wound epithelialization: Accelerating the pace of discovery. J Invest Dermatol 121:219-230.
    • (2003) J Invest Dermatol , vol.121 , pp. 219-230
    • Coulombe, P.-A.1
  • 2
    • 47749139256 scopus 로고    scopus 로고
    • Cancer as an overhealing wound: An old hypothesis revisited
    • Schäfer M, Werner S (2008) Cancer as an overhealing wound: An old hypothesis revisited. Nat Rev Mol Cell Biol 9:628-638.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 628-638
    • Schäfer, M.1    Werner, S.2
  • 3
    • 0022891340 scopus 로고
    • Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing
    • Dvorak H-F (1986) Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing. N Engl J Med 315:1650-1659.
    • (1986) N Engl J Med , vol.315 , pp. 1650-1659
    • Dvorak, H.-F.1
  • 4
    • 34248141100 scopus 로고    scopus 로고
    • A cytokine-mediated link between innate immunity, inflammation, and cancer
    • DOI 10.1172/JCI31537
    • Lin W-W, Karin M (2007) A cytokine-mediated link between innate immunity, inflammation, and cancer. J Clin Invest 117:1175-1183. (Pubitemid 46718402)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.5 , pp. 1175-1183
    • Lin, W.-W.1    Karin, M.2
  • 5
    • 0038819656 scopus 로고    scopus 로고
    • Contribution of stem cells and differentiated cells to epidermal tumours
    • Owens D-M, Watt F-M (2003) Contribution of stem cells and differentiated cells to epidermal tumours. Nat Rev Cancer 3:444-451.
    • (2003) Nat Rev Cancer , vol.3 , pp. 444-451
    • Owens, D.-M.1    Watt, F.-M.2
  • 6
    • 38749143649 scopus 로고    scopus 로고
    • Skin stem cells: Rising to the surface
    • Fuchs E (2008) Skin stem cells: Rising to the surface. J Cell Biol 180:273-284.
    • (2008) J Cell Biol , vol.180 , pp. 273-284
    • Fuchs, E.1
  • 7
    • 28444472423 scopus 로고    scopus 로고
    • Distinct stem cell populations regenerate the follicle and interfollicular epidermis
    • DOI 10.1016/j.devcel.2005.11.003, PII S1534580705004259
    • Levy V, Lindon C, Harfe B-D, Morgan B-A (2005) Distinct stem cell populations regenerate the follicle and interfollicular epidermis. Dev Cell 9:855-861. (Pubitemid 41724112)
    • (2005) Developmental Cell , vol.9 , Issue.6 , pp. 855-861
    • Levy, V.1    Lindon, C.2    Harfe, B.D.3    Morgan, B.A.4
  • 8
    • 0035868759 scopus 로고    scopus 로고
    • Multiple classes of stem cells in cutaneous epithelium: A lineage analysis of adult mouse skin
    • DOI 10.1093/emboj/20.6.1215
    • Ghazizadeh S, Taichman L-B (2001) Multiple classes of stem cells in cutaneous epithelium: A lineage analysis of adult mouse skin. EMBO J 20:1215-1222. (Pubitemid 32233962)
    • (2001) EMBO Journal , vol.20 , Issue.6 , pp. 1215-1222
    • Ghazizadeh, S.1    Taichman, L.B.2
  • 9
    • 0025313294 scopus 로고
    • Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis
    • Cotsarelis G, Sun T-T, Lavker R-M (1990) Label-retaining cells reside in the bulge area of pilosebaceous unit: Implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell 61:1329-1337.
    • (1990) Cell , vol.61 , pp. 1329-1337
    • Cotsarelis, G.1    Sun, T.-T.2    Lavker, R.-M.3
  • 10
    • 55049112939 scopus 로고    scopus 로고
    • Lgr5 marks cycling, yet long-lived, hair follicle stem cells
    • Jaks V, et al. (2008) Lgr5 marks cycling, yet long-lived, hair follicle stem cells. Nat Genet 40:1291-1299.
    • (2008) Nat Genet , vol.40 , pp. 1291-1299
    • Jaks, V.1
  • 11
    • 4444290010 scopus 로고    scopus 로고
    • Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche
    • DOI 10.1016/j.cell.2004.08.012, PII S0092867404007895
    • Blanpain C, Lowry W-E, Geoghegan A, Polak L, Fuchs E (2004) Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell 118:635-648. (Pubitemid 39179715)
    • (2004) Cell , vol.118 , Issue.5 , pp. 635-648
    • Blanpain, C.1    Lowry, W.E.2    Geoghegan, A.3    Polak, L.4    Fuchs, E.5
  • 12
    • 0034682742 scopus 로고    scopus 로고
    • Involvement of follicular stem cells in forming not only the follicle but also the epidermis
    • Taylor G, Lehrer M-S, Jensen P-J, Sun T-T, Lavker R-M (2000) Involvement of follicular stem cells in forming not only the follicle but also the epidermis. Cell 102:451-461.
    • (2000) Cell , vol.102 , pp. 451-461
    • Taylor, G.1    Lehrer, M.-S.2    Jensen, P.-J.3    Sun, T.-T.4    Lavker, R.-M.5
  • 13
    • 58949102946 scopus 로고    scopus 로고
    • A two-step mechanism for stem cell activation during hair regeneration
    • Greco V, et al. (2009) A two-step mechanism for stem cell activation during hair regeneration. Cell Stem Cell 4:155-169.
    • (2009) Cell Stem Cell , vol.4 , pp. 155-169
    • Greco, V.1
  • 14
    • 28644451449 scopus 로고    scopus 로고
    • Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis
    • DOI 10.1038/nm1328
    • Ito M, et al. (2005) Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis. Nat Med 11:1351-1354. (Pubitemid 41752917)
    • (2005) Nature Medicine , vol.11 , Issue.12 , pp. 1351-1354
    • Ito, M.1    Liu, Y.2    Yang, Z.3    Nguyen, J.4    Liang, F.5    Morris, R.J.6    Cotsarelis, G.7
  • 16
    • 33745203039 scopus 로고    scopus 로고
    • Epithelial stem cells: A folliculocentric view
    • Cotsarelis G (2006) Epithelial stem cells: A folliculocentric view. J Invest Dermatol 126:1459-1468.
    • (2006) J Invest Dermatol , vol.126 , pp. 1459-1468
    • Cotsarelis, G.1
  • 17
    • 77649258546 scopus 로고    scopus 로고
    • Identification of the cell lineage at the origin of basal cell carcinoma
    • Youssef K-K, et al. (2010) Identification of the cell lineage at the origin of basal cell carcinoma. Nat Cell Biol 12:299-305.
    • (2010) Nat Cell Biol , vol.12 , pp. 299-305
    • Youssef, K.-K.1
  • 18
    • 0030955557 scopus 로고    scopus 로고
    • Basal cell carcinomas in mice overexpressing sonic hedgehog
    • Oro A-E, et al. (1997) Basal cell carcinomas in mice overexpressing sonic hedgehog. Science 276:817-821.
    • (1997) Science , vol.276 , pp. 817-821
    • Oro, A.-E.1
  • 19
    • 15844381336 scopus 로고    scopus 로고
    • Human homolog of patched, a candidate gene for the basal cell nevus syndrome
    • Johnson R-L, et al. (1996) Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science 272:1668-1671.
    • (1996) Science , vol.272 , pp. 1668-1671
    • Johnson, R.-L.1
  • 21
    • 0030844141 scopus 로고    scopus 로고
    • Activation of the transcription factor Gli1 and the sonic hedgehog signalling pathway in skin tumours
    • DOI 10.1038/39918
    • Dahmane N, Lee J, Robins P, Heller P, Ruiz i Altaba A (1997) Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours. Nature 389:876-881. (Pubitemid 27462984)
    • (1997) Nature , vol.389 , Issue.6653 , pp. 876-881
    • Dahmane, N.1    Lee, J.2    Robins, P.3    Heller, P.4    Ruiz, I.A.A.5
  • 25
    • 1842529559 scopus 로고    scopus 로고
    • Capturing and profiling adult hair follicle stem cells
    • Morris R-J, et al. (2004) Capturing and profiling adult hair follicle stem cells. Nat Biotechnol 22:411-417.
    • (2004) Nat Biotechnol , vol.22 , pp. 411-417
    • Morris, R.-J.1
  • 26
    • 69949136621 scopus 로고    scopus 로고
    • Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis
    • Wong S-Y, et al. (2009) Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis. Nat Med 15:1055-1061.
    • (2009) Nat Med , vol.15 , pp. 1055-1061
    • Wong, S.-Y.1
  • 28
    • 38649106497 scopus 로고    scopus 로고
    • NFATc1 Balances Quiescence and Proliferation of Skin Stem Cells
    • DOI 10.1016/j.cell.2007.11.047, PII S0092867407016145
    • Horsley V, Aliprantis A-O, Polak L, Glimcher L-H, Fuchs E (2008) NFATc1 balances quiescence and proliferation of skin stem cells. Cell 132:299-310. (Pubitemid 351172432)
    • (2008) Cell , vol.132 , Issue.2 , pp. 299-310
    • Horsley, V.1    Aliprantis, A.O.2    Polak, L.3    Glimcher, L.H.4    Fuchs, E.5
  • 29
    • 34249275713 scopus 로고    scopus 로고
    • CD34 expression by hair follicle stem cells is required for skin tumor development in mice
    • Trempus C-S, et al. (2007) CD34 expression by hair follicle stem cells is required for skin tumor development in mice. Cancer Res 67:4173-4181.
    • (2007) Cancer Res , vol.67 , pp. 4173-4181
    • Trempus, C.-S.1
  • 30
    • 23244443556 scopus 로고    scopus 로고
    • Sox9 is essential for outer root sheath differentiation and the formation of the hair stem cell compartment
    • Vidal V-P, et al. (2005) Sox9 is essential for outer root sheath differentiation and the formation of the hair stem cell compartment. Curr Biol 15:1340-1351.
    • (2005) Curr Biol , vol.15 , pp. 1340-1351
    • Vidal, V.-P.1
  • 31
    • 48649085299 scopus 로고    scopus 로고
    • Hair follicle stem cells are specified and function in early skin morphogenesis
    • Nowak J-A, Polak L, Pasolli H-A, Fuchs E (2008) Hair follicle stem cells are specified and function in early skin morphogenesis. Cell Stem Cell 3:33-43.
    • (2008) Cell Stem Cell , vol.3 , pp. 33-43
    • Nowak, J.-A.1    Polak, L.2    Pasolli, H.-A.3    Fuchs, E.4
  • 32
    • 0030866154 scopus 로고    scopus 로고
    • Altered neural cell fates and medulloblastoma in mouse patched mutants
    • DOI 10.1126/science.277.5329.1109
    • Goodrich L-V, Milenković L, Higgins K-M, Scott M-P (1997) Altered neural cell fates and medulloblastoma in mouse patched mutants. Science 277:1109-1113. (Pubitemid 27371635)
    • (1997) Science , vol.277 , Issue.5329 , pp. 1109-1113
    • Goodrich, L.V.1    Milenkovic, L.2    Higgins, K.M.3    Scott, M.P.4
  • 34
    • 0018879206 scopus 로고
    • Basal cell carcinoma arising in a smallpox vaccination site
    • Rich J-D, Shesol B-F, 3rd, Horne D-W, 3rd (1980) Basal cell carcinoma arising in a smallpox vaccination site. J Clin Pathol 33:134-135.
    • (1980) J Clin Pathol , vol.33 , pp. 134-135
    • Rich, J.-D.1    Shesol III, B.-F.2    Horne III, D.-W.3
  • 35
    • 0014309422 scopus 로고
    • Basal cell epithelioma at site and following smallpox and vaccination
    • Zelickson A-S (1968) Basal cell epithelioma at site and following smallpox and vaccination. Arch Dermatol 98:35-36.
    • (1968) Arch Dermatol , vol.98 , pp. 35-36
    • Zelickson, A.-S.1
  • 36
    • 0033371950 scopus 로고    scopus 로고
    • Basal cell carcinoma arising from surgical scars: A case and review of the literature
    • DOI 10.1046/j.1524-4725.1999.99192.x
    • Ozyazgan I, Kontaçs O (1999) Basal cell carcinoma arising from surgical scars: A case and review of the literature. Dermatol Surg 25:965-968. (Pubitemid 30021620)
    • (1999) Dermatologic Surgery , vol.25 , Issue.12 , pp. 965-968
    • Ozyazgan, I.1    Kontas, O.2
  • 38
    • 0031036797 scopus 로고    scopus 로고
    • Basal cell carcinoma developing on a burn scar
    • DOI 10.1016/S0305-4179(96)00077-0, PII S0305417996000770
    • Koga Y, Sawada Y (1997) Basal cell carcinoma developing on a burn scar. Burns 23:75-77. (Pubitemid 27051141)
    • (1997) Burns , vol.23 , Issue.1 , pp. 75-77
    • Koga, Y.1    Sawada, Y.2
  • 41
    • 33847138972 scopus 로고    scopus 로고
    • Promotion of Hras-induced squamous carcinomas by a polymorphic variant of the Patched gene in FVB mice
    • DOI 10.1038/nature05489, PII NATURE05489
    • Wakabayashi Y, Mao J-H, Brown K, Girardi M, Balmain A (2007) Promotion of Hras-induced squamous carcinomas by a polymorphic variant of the Patched gene in FVB mice. Nature 445:761-765. (Pubitemid 46279707)
    • (2007) Nature , vol.445 , Issue.7129 , pp. 761-765
    • Wakabayashi, Y.1    Mao, J.-H.2    Brown, K.3    Girardi, M.4    Balmain, A.5
  • 42
    • 0016615917 scopus 로고
    • The effect of aging and interval between primary and secondary treatment in two-stage carcinogenesis on mouse skin
    • Van Duuren B-L, Sivak A, Katz C, Seidman I, Melchionne S (1975) The effect of aging and interval between primary and secondary treatment in two-stage carcinogenesis on mouse skin. Cancer Res 35:502-505.
    • (1975) Cancer Res , vol.35 , pp. 502-505
    • Van Duuren, B.-L.1    Sivak, A.2    Katz, C.3    Seidman, I.4    Melchionne, S.5
  • 43
    • 0020964397 scopus 로고
    • On the persistence of tumor initiation in two-stage carcinogenesis on mouse skin
    • Loehrke H, et al. (1983) On the persistence of tumor initiation in two-stage carcinogenesis on mouse skin. Carcinogenesis 4:771-775. (Pubitemid 13028139)
    • (1983) Carcinogenesis , vol.4 , Issue.6 , pp. 771-775
    • Loehrke, H.1    Schweizer, J.2    Dederer, E.3
  • 44
    • 79952745374 scopus 로고    scopus 로고
    • Wounding enhances epidermal tumorigenesis by recruiting hair follicle keratinocytes
    • Kasper M, et al. (2011) Wounding enhances epidermal tumorigenesis by recruiting hair follicle keratinocytes. Proc Natl Acad Sci USA 108:4099-4104.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 4099-4104
    • Kasper, M.1
  • 45
    • 77953697794 scopus 로고    scopus 로고
    • Differential sensitivity of epidermal cell subpopulations to β-catenin-induced ectopic hair follicle formation
    • Baker C-M, Verstuyf A, Jensen K-B, Watt F-M (2010) Differential sensitivity of epidermal cell subpopulations to β-catenin-induced ectopic hair follicle formation. Dev Biol 343:40-50.
    • (2010) Dev Biol , vol.343 , pp. 40-50
    • Baker, C.-M.1    Verstuyf, A.2    Jensen, K.-B.3    Watt, F.-M.4
  • 46
    • 32044436273 scopus 로고    scopus 로고
    • Dual degradation signals control Gli protein stability and tumor formation
    • Huntzicker E-G, et al. (2006) Dual degradation signals control Gli protein stability and tumor formation. Genes Dev 20:276-281.
    • (2006) Genes Dev , vol.20 , pp. 276-281
    • Huntzicker, E.-G.1
  • 47
    • 42149108455 scopus 로고    scopus 로고
    • Controlling hair follicle signaling pathways through polyubiquitination
    • Huntzicker E-G, Oro A-E (2008) Controlling hair follicle signaling pathways through polyubiquitination. J Invest Dermatol 128:1081-1087.
    • (2008) J Invest Dermatol , vol.128 , pp. 1081-1087
    • Huntzicker, E.-G.1    Oro, A.-E.2
  • 48
    • 33846000938 scopus 로고    scopus 로고
    • Bone morphogenetic protein signaling inhibits hair follicle anagen induction by restricting epithelial stem/progenitor cell activation and expansion
    • DOI 10.1634/stemcells.2005-0544
    • Zhang J, et al. (2006) Bone morphogenetic protein signaling inhibits hair follicle anagen induction by restricting epithelial stem/progenitor cell activation and expansion. Stem Cells 24:2826-2839. (Pubitemid 46053019)
    • (2006) Stem Cells , vol.24 , Issue.12 , pp. 2826-2839
    • Zhang, J.1    He, X.C.2    Tong, W.-G.3    Johnson, T.4    Wiedemann, L.M.5    Mishina, Y.6    Feng, J.Q.7    Li, L.8
  • 50
    • 0028141884 scopus 로고
    • Inflammation is responsible for the development of wound-induced tumors in chickens infected with Rous sarcoma virus
    • Martins-Green M, Boudreau N, Bissell M-J (1994) Inflammation is responsible for the development of wound-induced tumors in chickens infected with Rous sarcoma virus. Cancer Res 54:4334-4341. (Pubitemid 24273144)
    • (1994) Cancer Research , vol.54 , Issue.16 , pp. 4334-4341
    • Martins-Green, M.1    Boudreau, N.2    Bissell, M.J.3
  • 51
    • 0032983865 scopus 로고    scopus 로고
    • Mice deficient in tumor necrosis factor-α are resistant to skin carcinogenesis
    • Moore R-J, et al. (1999) Mice deficient in tumor necrosis factor-α are resistant to skin carcinogenesis. Nat Med 5:828-831.
    • (1999) Nat Med , vol.5 , pp. 828-831
    • Moore, R.-J.1


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