Acute stress response modified by modest inhibition of growth hormone axis: A potential machinery of the anti-aging effect of calorie restriction

Mechanisms of Ageing and Development

Volumn 132, Issue 3, 2011, Pages 103-109

  Komatsu, Toshimitsu ^a   Trindade, Lucas S ^a   Chiba, Takuya ^a   Hayashi, Hiroko ^a   Henmi, Tomoko ^a   Ushiroda, Yoko ^a   Mori, Ryoichi ^a   Shimokawa, Isao ^a  

^a NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

Author keywords

Calorie restriction; Endotoxin; Growth hormone; Inflammation

Indexed keywords

ASPARTATE AMINOTRANSFERASE; GAMMA INTERFERON; GROWTH HORMONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; SOMATOMEDIN C; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA;

ACUTE STRESS; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CALORIC RESTRICTION; CONTROLLED STUDY; ENZYME ACTIVATION; FEEDING; FEMALE; GENE OVEREXPRESSION; HETEROZYGOSITY; HORMONE INHIBITION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; TISSUE INJURY; TRANSGENIC RAT; WILD TYPE;

ACUTE-PHASE REACTION; AGING; ANIMALS; CALORIC RESTRICTION; CYTOKINES; INSULIN-LIKE GROWTH FACTOR I; LIPOPOLYSACCHARIDES; MALE; NF-KAPPA B; RATS; RATS, TRANSGENIC; TRANSCRIPTION FACTOR AP-1;

RATTUS;

EID: 79952740766     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2011.01.002     Document Type: Article

References (43)

1. Apte U.M., Limaye P.B., Ramaiah S.K., Vaidya V.S., Bucci T.J., Warbritton A., Mehendale H.M. Upregulated promitogenic signaling via cytokines and growth factors: potential mechanism of robust liver tissue repair in calorie-restricted rats upon toxic challenge. Toxicol. Sci. 2002, 69:448-459.
2. Bartke A., Wright J.C., Mattison J.A., Ingram D.K., Miller R.A., Roth G.S. Extending the lifespan of long-lived mice. Nature 2001, 414:412.
3. Bonkowski M.S., Rocha J.S., Masternak M.M., Al Regaiey K.A., Bartke A. Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:7901-7905.
4. Breese C.R., Ingram R.L., Sonntag W.E. Influence of age and long-term dietary restriction on plasma insulin-like growth factor-1 (IGF-1) IGF-1 gene expression, and IGF-1 binding proteins. J. Gerontol. 1991, 46:B180-B187.
5. Chandrashekar V., Bartke A. Induction of endogenous insulin-like growth factor-I secretion alters the hypothalamic-pituitary-testicular function in growth hormone-deficient adult dwarf mice. Biol. Reprod. 1993, 48:544-551.
6. Chiba T., Yamaza H., Komatsu T., Nakayama M., Fujita S., Hayashi H., Higami Y., Shimokawa I. Pituitary growth hormone suppression reduces resistin expression and enhances insulin effectiveness: relationship with caloric restriction. Exp. Gerontol. 2008, 43:595-600.
7. Chung H.Y., Sung B., Jung K.J., Zou Y., Yu B.P. The molecular inflammatory process in aging. Antioxid. Redox Signal 2006, 8:572-581.
8. Corsini E., Terzoli A., Bruccoleri A., Marinovich M., Galli C.L. Induction of tumor necrosis factor-alpha in vivo by a skin irritant, tributyltin, through activation of transcription factors: its pharmacological modulation by anti-inflammatory drugs. J. Invest. Dermatol. 1997, 108:892-896.
9. Coschigano K.T., Clemmons D., Bellush L.L., Kopchick J.J. Assessment of growth parameters and life span of GHR/BP gene-disrupted mice. Endocrinology 2000, 141:2608-2613.
10. Edwards C.K., Ghiasuddin S.M., Schepper J.M., Yunger L.M., Kelley K.W. A newly defined property of somatotrop priming of macrophages for production of superoxide anion. Science 1988, 239:769-771.
11. Edwards C.K., Ghiasuddin S.M., Yunger L.M., Lorence R.M., Arkins S., Dantzer R., Kelley K.W. In vivo administration of recombinant growth hormone or gamma interferon activities macrophages: enhanced resistance to experimental Salmonella typhimurium infection is correlated with generation of reactive oxygen intermediates. Infect. Immun. 1992, 60:2514-2521.
12. Fan J., Char D., Kolasa A.J., Pan W., Maitra S.R., Patlak C.S., Spolarics Z., Gelato M.C., Lang C.H. Alterations in hepatic production and peripheral clearance of IGF-I after endotoxin. Am. J. Physiol. 1995, 269:E33-E42.
13. Fu Y.K., Arkins S., Wang B.S., Kelley K.W. A novel role of growth hormone and insulin-like growth factor-I Priming neutrophils for superoxide anion secretion. J. Immunol. 1991, 146:1602-1608.
14. Gao C., Jokerst R., Gondipalli P., Cai S.R., Kennedy S., Flye M.W., Ponder K.P. Lipopolysaccharide potentiates the effect of hepatocyte growth factor on hepatocyte replication in rats by augmenting AP-1 activity. Hepatology 1999, 30:1405-1416.
15. Guha M., Mackman N. LPS induction of gene expression in human monocytes. Cell Signal 2001, 13:85-94.
16. Harper J.M., Salmon A.B., Chang Y., Bonkowski M., Bartke A., Miller R.A. Stress resistance and aging: influence of genes and nutrition. Mech. Ageing Dev. 2006, 127:687-694.
17. Hauck S.J., Aaron J.M., Wright C., Kopchick J.J., Bartke A. Antioxidant enzymes, free-radical damage, and response to paraquat in liver and kidney of long-living growth hormone receptor/binding protein gene-disrupted mice. Horm. Metab. Res. 2002, 34:481-486.
18. Holzenberger M., Dupont J., Ducos B., Leneuve P., Géloën A., Even P.C., Cervera P., Le Bouc Y. IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice. Nature 2003, 421:182-187.
19. Hsu S.M., Raine L., Fanger H. The use of antiavidin antibody and avidin-biotin-peroxidase complex in immunoperoxidase technics. Am. J. Clin. Pathol. 1981, 75:816-821.
20. Kim H.J., Jung K.J., Yu B.P., Cho C.G., Chung H.Y. Influence of aging and calorie restriction on MAPKs activity in rat kidney. Exp. Gerontol. 2002, 37:1041-1053.
21. Kim H.J., Yu B.P., Chung H.Y. Molecular exploration of age-related NF-kappaB/IKK downregulation by calorie restriction in rat kidney. Free Radic. Biol. Med. 2002, 32:991-1005.
22. Klöcker U., Schultz U., Schaller H., Protzer U. Endotoxin stimulates liver macrophages to release mediators that inhibit an early step in hepadnavirus replication. J. Virol. 2000, 74:5525-5533.
23. Liao W., Rudling M., Angelin B. Growth hormone potentiates the in vivo biological activities of endotoxin in the rat. Eur. J. Clin. Invest. 1996, 26:254-258.
24. Liao W., Rudling M., Angelin B. Contrasting effects of growth hormone and insulin-like growth factor I on the biological activities of endotoxin in the rat. Endocrinology 1997, 138:289-295.
25. Madsen M.A., Hsieh C.-C., Boylston W.H., Flurkey K., Harrison D., Papaconstantinou J. Altered oxidative stress response of the long-lived Snell dwarf mouse. Biochem. Biophys. Res. Commun. 2004, 318:998-1005.
26. Masoro E.J. Hormesis and the antiaging action of dietary restriction. Exp. Gerontol. 1998, 33:61-66.
27. Masoro E.J. Subfield history: caloric restriction, slowing aging, and extending life. Sci. Aging Knowl. Environ. 2003, 2003:RE2.
28. Matsumoto K., Kakidani H., Takahashi A., Nakagata N., Anzai M., Matsuzaki Y., Takahashi Y., Miyata K., Utsumi K., Iritani A. Growth retardation in rats whose growth hormone gene expression was suppressed by antisense RNA transgene. Mol. Reprod. Dev. 1993, 36:53-58.
29. Murakami S., Salmon A., Miller R.A. Multiplex stress resistance in cells from long-lived dwarf mice. FASEB J. 2003, 17:1565-1566.
30. Ouchi N., Kihara S., Arita Y., Maeda K., Kuriyama H., Okamoto Y., Hotta K., Nishida M., Takahashi M., Nakamura T., Yamashita S., Funahashi T., Matsuzawa Y. Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. Circulation 1999, 100:2473-2476.
31. Panici J.A., Harper J.M., Miller R.A., Bartke A., Spong A., Masternak M.M. Early life growth hormone treatment shortens longevity and decreases cellular stress resistance in long-lived mutant mice. FASEB J. 2010, 24:5073-5079.
32. Sanz A., Gredilla R., Pamplona R., Portero-Otín M., Vara E., Tresguerres J.A., Barja G. Effect of insulin and growth hormone on rat heart and liver oxidative stress in control and caloric restricted animals. Biogerontology 2005, 6:15-26.
33. Schumacher B., van der Pluijm I., Moorhouse M.J., Kosteas T., Robinson A.R., Suh Y., Breit T.M., van Steeg H., Niedernhofer L.J., van Ijcken W., Bartke A., Spindler S.R., Hoeijmakers J.H., van der Horst G.T., Garinis G.A. Delayed and accelerated aging share common longevity assurance mechanisms. PLoS Genet. 2008, 4:e1000161.
34. Shimokawa I., Chiba T., Yamaza H., Komatsu T. Longevity genes: insights from calorie restriction and genetic longevity models. Mol. Cells 2008, 26:427-435.
35. Shimokawa I., Higami Y., Tsuchiya T., Otani H., Komatsu T., Chiba T., Yamaza H. Life span extension by reduction of the growth hormone-insulin-like growth factor-1 axis: relation to caloric restriction. FASEB J. 2003, 17:1108-1109.
36. Shimokawa I., Higami Y., Utsuyama M., Tuchiya T., Komatsu T., Chiba T., Yamaza H. Life span extension by reduction in growth hormone-insulin-like growth factor-1 axis in a transgenic rat model. Am. J. Pathol. 2002, 160:2259-2265.
37. Stefanski S.A., Elwell M.R. Spleen, lymph nodes, and thymus. Pathology of the Fischer Rat 1990, 369-393. Academic Press Inc., San Diego, CA. G.A. Boorman (Ed.).
38. Sun D., Muthukumar A.R., Lawrence R.A., Fernandes G. Effects of calorie restriction on polymicrobial peritonitis induced by cecum ligation and puncture in young C57BL/6 mice. Clin. Diagn. Lab. Immunol. 2001, 8:1003-1011.
39. Tsuchiya T., Higami Y., Komatsu T., Tanaka K., Honda S., Yamaza H., Chiba T., Ayabe H., Shimokawa I. Acute stress response in calorie-restricted rats to lipopolysaccharide-induced inflammation. Mech. Ageing Dev. 2005, 126:568-579.
40. Van Amersfoort E.S., Van Berkel T.J.C., Kuiper J. Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock. Clin. Microbiol. Rev. 2003, 16:379-414.
41. Wang X., Jiang J., Warram J., Baumann G., Gan Y., Menon R.K., Denson L.A., Zinn K.R., Frank S.J. Endotoxin-induced proteolytic reduction in hepatic growth hormone (GH) receptor: a novel mechanism for GH insensitivity. Mol. Endocrinol. 2008, 22:1427-1437.
42. 2. J. Immunol. 1995, 154:1909-1918.
43. Yamaza Y., Komatsu T., To K., Toyama H., Chiba T., Higami Y., Shimokawa I. Involvement of insulin-like growth Factor-1 in the effect of caloric restriction: regulation of plasma adiponectin and leptin. J. Gerontol. A Biol. Sci. Med. Sci. 2007, 62A:27-33.