Regulation of vascular smooth muscle cell calcification by extracellular pyrophosphate homeostasis: Synergistic modulation by cyclic AMP and hyperphosphatemia

American Journal of Physiology - Cell Physiology

Volumn 298, Issue 3, 2010, Pages

  Prosdocimo, Domenick A ^a   Wyler, Steven C ^a   Romani, Andrea M ^a   O'Neill, W Charles ^b   Dubyak, George R ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adenosine 3 ,5 cyclic monophosphate; ANK; ATP release; Ectonucleotide pyrophosphatase phosphodiesterase 1

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALPHA SMOOTH MUSCLE ACTIN; ANK PROTEIN; CALPONIN; CYCLIC AMP; ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1; MEMBRANE PROTEIN; PHOSPHATE; PYROPHOSPHATE; SMOOTH MUSCLE 22ALPHA; SMOOTH MUSCLE ACTIN; TISSUE NONSELECTIVE ALKALINE PHOSPHATASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL CALCIFICATION; CELL CULTURE; CELL DIFFERENTIATION; CELL STIMULATION; CONTROLLED STUDY; DISEASE COURSE; DISEASE PREDISPOSITION; ENZYME ACTIVITY; HYPERPHOSPHATEMIA; MALE; NONHUMAN; PHOSPHATE METABOLISM; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ADENOSINE TRIPHOSPHATE; ALKALINE PHOSPHATASE; ANIMALS; AUTOCRINE COMMUNICATION; CALCINOSIS; CALCIUM-BINDING PROTEINS; CELLS, CULTURED; CYCLIC AMP; DIPHOSPHATES; HOMEOSTASIS; HYPERPHOSPHATEMIA; KINETICS; MALE; MEMBRANE PROTEINS; MICROFILAMENT PROTEINS; MUSCLE PROTEINS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PHOSPHORIC DIESTER HYDROLASES; PYROPHOSPHATASES; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

RATTUS;

EID: 77749264513     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00419.2009     Document Type: Article

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