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Volumn 19, Issue 6, 2008, Pages 1092-1105

The mechanism of phosphorus as a cardiovascular risk factor in CKD

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; NOGGIN; OSTEOGENIC PROTEIN 1; PHOSPHATE BINDING AGENT; PHOSPHORUS; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2;

EID: 48049102175     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2007070760     Document Type: Article
Times cited : (215)

References (52)
  • 1
    • 4644221457 scopus 로고    scopus 로고
    • Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization
    • Go AS, Chertow GM, Fan D, McCulloch CE, Hsu Cy: Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 351: 1296-1305, 2004
    • (2004) N Engl J Med , vol.351 , pp. 1296-1305
    • Go, A.S.1    Chertow, G.M.2    Fan, D.3    McCulloch, C.E.4    Hsu, C.5
  • 2
    • 33846031473 scopus 로고    scopus 로고
    • Kidney-heart interactions: Epidemiology, pathogenesis, and treatment
    • Berl T, Henrich W: Kidney-heart interactions: Epidemiology, pathogenesis, and treatment. Clin J Am Soc Nephrol 1: 8-18, 2006
    • (2006) Clin J Am Soc Nephrol , vol.1 , pp. 8-18
    • Berl, T.1    Henrich, W.2
  • 4
    • 26944445097 scopus 로고    scopus 로고
    • Calcium, phosphorus, parathyroid hormone, and cardiovascular disease in hemodialysis patients: The USRDS Waves 1, 3, and 4 Study
    • Slinin Y, Foley RN, Collins AJ: Calcium, phosphorus, parathyroid hormone, and cardiovascular disease in hemodialysis patients: The USRDS Waves 1, 3, and 4 Study. J Am Soc Nephrol 16: 1788-1793, 2005
    • (2005) J Am Soc Nephrol , vol.16 , pp. 1788-1793
    • Slinin, Y.1    Foley, R.N.2    Collins, A.J.3
  • 5
    • 0042885985 scopus 로고    scopus 로고
    • Arterial media calcification in end-stage renal diseases: Impact on all-cause and cardiovascular mortality
    • London GM, Guerin AP, Marchais SJ, Metivier F, Pannier B, Adda H: Arterial media calcification in end-stage renal diseases: Impact on all-cause and cardiovascular mortality. Nephrol Dial Transplant 18: 1731-1740, 2003
    • (2003) Nephrol Dial Transplant , vol.18 , pp. 1731-1740
    • London, G.M.1    Guerin, A.P.2    Marchais, S.J.3    Metivier, F.4    Pannier, B.5    Adda, H.6
  • 6
    • 0037138580 scopus 로고    scopus 로고
    • Cardiac calcification in adult hemodialysis patients: A link between end-stage renal disease and cardiovascular disease?
    • Raggi P, Boulay A, Chasan-Taber S, Amin N, Dillon M, Burke SK, Chertow GM: Cardiac calcification in adult hemodialysis patients: A link between end-stage renal disease and cardiovascular disease? J Am Coll Cardiol 39: 695-701, 2002
    • (2002) J Am Coll Cardiol , vol.39 , pp. 695-701
    • Raggi, P.1    Boulay, A.2    Chasan-Taber, S.3    Amin, N.4    Dillon, M.5    Burke, S.K.6    Chertow, G.M.7
  • 7
    • 3843094224 scopus 로고    scopus 로고
    • Diastolic heart failure: Abnormalities in active relaxation and passive stiffness of the left ventricle
    • Zile MR, Baicu CF, Gaasch WH: Diastolic heart failure: Abnormalities in active relaxation and passive stiffness of the left ventricle. N Engl J Med 350: 1953-1959, 2004
    • (2004) N Engl J Med , vol.350 , pp. 1953-1959
    • Zile, M.R.1    Baicu, C.F.2    Gaasch, W.H.3
  • 8
    • 24344477577 scopus 로고    scopus 로고
    • High prevalence of occult coronary artery stenosis in patients with chronic kidney disease at the initiation of renal replacement therapy: An angiographic examination
    • Ohtake T, Kobayashi S, Moriya H, Negishi K, Okamoto K, Maesato K, Saito S: High prevalence of occult coronary artery stenosis in patients with chronic kidney disease at the initiation of renal replacement therapy: An angiographic examination. J Am Soc Nephrol 16: 1141-1148, 2005
    • (2005) J Am Soc Nephrol , vol.16 , pp. 1141-1148
    • Ohtake, T.1    Kobayashi, S.2    Moriya, H.3    Negishi, K.4    Okamoto, K.5    Maesato, K.6    Saito, S.7
  • 9
    • 0037341318 scopus 로고    scopus 로고
    • Osteo/chondrocytic transcription factors and their target genes exhibit distinct patterns of expression in human arterial calcification
    • Tyson KL, Reynolds JL, McNair R Zhang Q, Weissberg PL, Shanahan CM: Osteo/chondrocytic transcription factors and their target genes exhibit distinct patterns of expression in human arterial calcification. Arterioscler Thromb Vasc Biol 23: 489-494, 2003
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 489-494
    • Tyson, K.L.1    Reynolds, J.L.2    McNair, R.3    Zhang, Q.4    Weissberg, P.L.5    Shanahan, C.M.6
  • 12
    • 14544283020 scopus 로고    scopus 로고
    • Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: A potential mechanism for accelerated vascular calcification in ESRD
    • Reynolds JL, Joannides AJ, Skepper JN, McNair R, Schurgers LJ, Proudfoot D, Jahnen-Dechent W, Weissberg PL, Shanahan CM: Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: A potential mechanism for accelerated vascular calcification in ESRD. J Am Soc Nephrol 15: 2857-2867, 2004
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2857-2867
    • Reynolds, J.L.1    Joannides, A.J.2    Skepper, J.N.3    McNair, R.4    Schurgers, L.J.5    Proudfoot, D.6    Jahnen-Dechent, W.7    Weissberg, P.L.8    Shanahan, C.M.9
  • 13
    • 3042733616 scopus 로고    scopus 로고
    • Vascular smooth muscle cells and calcification in atherosclerosis
    • Trion A, van der Laarse A: Vascular smooth muscle cells and calcification in atherosclerosis. Am Heart J 147: 808-814, 2004
    • (2004) Am Heart J , vol.147 , pp. 808-814
    • Trion, A.1    van der Laarse, A.2
  • 17
    • 0030678549 scopus 로고    scopus 로고
    • Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation
    • Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G: Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation. Cell 89: 747-754, 1997
    • (1997) Cell , vol.89 , pp. 747-754
    • Ducy, P.1    Zhang, R.2    Geoffroy, V.3    Ridall, A.L.4    Karsenty, G.5
  • 18
    • 0037337818 scopus 로고    scopus 로고
    • Uremia induces the osteoblast differentiation factor Cbfa1 in human blood vessels
    • Moe SM, Duan D, Doehle BP, O'Neill KD, Chen NX: Uremia induces the osteoblast differentiation factor Cbfa1 in human blood vessels. Kidney Int 63: 1003-1011, 2003
    • (2003) Kidney Int , vol.63 , pp. 1003-1011
    • Moe, S.M.1    Duan, D.2    Doehle, B.P.3    O'Neill, K.D.4    Chen, N.X.5
  • 19
    • 0037835949 scopus 로고    scopus 로고
    • BMP-7 is an efficacious treatment of vascular calcification in a murine model of atherosclerosis and chronic renal failure
    • Davies MR, Lund RJ, Hruska KA: BMP-7 is an efficacious treatment of vascular calcification in a murine model of atherosclerosis and chronic renal failure. J Am Soc Nephrol 14: 1559-1567, 2003
    • (2003) J Am Soc Nephrol , vol.14 , pp. 1559-1567
    • Davies, M.R.1    Lund, R.J.2    Hruska, K.A.3
  • 20
    • 20844462829 scopus 로고    scopus 로고
    • Low turnover osteodystrophy and vascular calcification are amenable to skeletal anabolism in an animal model of chronic kidney disease and the metabolic syndrome
    • Davies MR, Lund RJ, Mathew S, Hruska KA: Low turnover osteodystrophy and vascular calcification are amenable to skeletal anabolism in an animal model of chronic kidney disease and the metabolic syndrome. J Am Soc Nephrol 16: 917-928, 2005
    • (2005) J Am Soc Nephrol , vol.16 , pp. 917-928
    • Davies, M.R.1    Lund, R.J.2    Mathew, S.3    Hruska, K.A.4
  • 21
    • 0942287106 scopus 로고    scopus 로고
    • Successful treatment of an adynamic bone disorder with bone morphogenetic protein-7 in a renal ablation model
    • Lund RJ, Davies MR, Brown AJ, Hruska KA: Successful treatment of an adynamic bone disorder with bone morphogenetic protein-7 in a renal ablation model. J Am Soc Nephrol 15: 359-369, 2004
    • (2004) J Am Soc Nephrol , vol.15 , pp. 359-369
    • Lund, R.J.1    Davies, M.R.2    Brown, A.J.3    Hruska, K.A.4
  • 22
    • 33646157733 scopus 로고    scopus 로고
    • Role of the sodium-dependent phosphate cotransporter, Pit-1, in vascular smooth muscle cell calcification
    • Li X, Yang HY, Giachelli CM: Role of the sodium-dependent phosphate cotransporter, Pit-1, in vascular smooth muscle cell calcification. Circ Res 98: 905-912, 2006
    • (2006) Circ Res , vol.98 , pp. 905-912
    • Li, X.1    Yang, H.Y.2    Giachelli, C.M.3
  • 23
    • 0030698388 scopus 로고    scopus 로고
    • Regulation of bone matrix protein expression and induction of differentiation of human osteoblasts and human bone marrow stromal cells by bone morphogenetic protein-2
    • Lecanda F, Avioli LV, Cheng SL: Regulation of bone matrix protein expression and induction of differentiation of human osteoblasts and human bone marrow stromal cells by bone morphogenetic protein-2. J Cell Biochem 67: 386-398, 1997
    • (1997) J Cell Biochem , vol.67 , pp. 386-398
    • Lecanda, F.1    Avioli, L.V.2    Cheng, S.L.3
  • 24
    • 0037059614 scopus 로고    scopus 로고
    • The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation
    • Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR, De Crombrugghe B: The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell 108: 17-29, 2002
    • (2002) Cell , vol.108 , pp. 17-29
    • Nakashima, K.1    Zhou, X.2    Kunkel, G.3    Zhang, Z.4    Deng, J.M.5    Behringer, R.R.6    De Crombrugghe, B.7
  • 26
    • 0032515059 scopus 로고    scopus 로고
    • Dietinduced diabetes activates an osteogenic gene regulatory program in the aortas of low density lipoprotein receptor-deficient mice
    • Towler DA, Bidder M, Latifi T, Coleman T, Semenkovich CF: Dietinduced diabetes activates an osteogenic gene regulatory program in the aortas of low density lipoprotein receptor-deficient mice. J Biol Chem 273: 30427-30434, 1998
    • (1998) J Biol Chem , vol.273 , pp. 30427-30434
    • Towler, D.A.1    Bidder, M.2    Latifi, T.3    Coleman, T.4    Semenkovich, C.F.5
  • 28
    • 0034074899 scopus 로고    scopus 로고
    • Bone morphogenetic protein-7 (osteogenic protein-1) inhibits smooth muscle cell proliferation and stimulates the expression of markers that are characteristic of SMC phenotype in vitro
    • Dorai H, Vukicevic S, Sampath TK: Bone morphogenetic protein-7 (osteogenic protein-1) inhibits smooth muscle cell proliferation and stimulates the expression of markers that are characteristic of SMC phenotype in vitro. J Cell Physiol 184: 37-45, 2000
    • (2000) J Cell Physiol , vol.184 , pp. 37-45
    • Dorai, H.1    Vukicevic, S.2    Sampath, T.K.3
  • 29
    • 0035221551 scopus 로고    scopus 로고
    • Bone morphogenetic protein-7 modulates genes that maintain the vascular smooth muscle cell phenotype in culture
    • Dorai H, Sampath TK: Bone morphogenetic protein-7 modulates genes that maintain the vascular smooth muscle cell phenotype in culture. J Bone Joint Surg 83: S70-S78, 2001
    • (2001) J Bone Joint Surg , vol.83
    • Dorai, H.1    Sampath, T.K.2
  • 30
    • 33845982605 scopus 로고    scopus 로고
    • Reversal of the adynamic bone disorder and decreased vascular calcification in chronic kidney disease by sevelamer carbonate therapy
    • Mathew S, Lund R, Strebeck F, Tustison KS, Geurs T, Hruska KA: Reversal of the adynamic bone disorder and decreased vascular calcification in chronic kidney disease by sevelamer carbonate therapy. J Am Soc Nephrol 18: 122-130, 2007
    • (2007) J Am Soc Nephrol , vol.18 , pp. 122-130
    • Mathew, S.1    Lund, R.2    Strebeck, F.3    Tustison, K.S.4    Geurs, T.5    Hruska, K.A.6
  • 31
    • 0002640027 scopus 로고    scopus 로고
    • The osteoblast lineage
    • edited by Bilezikian JP, Raisz LG, Rodan GA, New York, Academic Press
    • Aubin JE, Liu F: The osteoblast lineage. In: Principles of Bone Biology, edited by Bilezikian JP, Raisz LG, Rodan GA, New York, Academic Press, 1996, pp 51-67
    • (1996) Principles of Bone Biology , pp. 51-67
    • Aubin, J.E.1    Liu, F.2
  • 32
    • 0028587853 scopus 로고
    • Transcriptional control of the tissue-specific, developmentally regulated osteocalcin gene requires a binding motif for the Msx family of homeodomain proteins
    • Hoffmann HM, Catron KM, van Wijnen AJ, McCabe LR, Lian JB, Stein GS, Stein JL: Transcriptional control of the tissue-specific, developmentally regulated osteocalcin gene requires a binding motif for the Msx family of homeodomain proteins. Proc Natl Acad Sci USA 91: 12887-12891, 1994
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 12887-12891
    • Hoffmann, H.M.1    Catron, K.M.2    van Wijnen, A.J.3    McCabe, L.R.4    Lian, J.B.5    Stein, G.S.6    Stein, J.L.7
  • 33
    • 0242664267 scopus 로고    scopus 로고
    • Msx2 promotes osteogenesis and suppresses adipogenic differentiation of multipotent mesenchymal progenitors
    • Cheng SL, Shao JS, Charlton-Kachigian N, Loewy AP, Towler DA: Msx2 promotes osteogenesis and suppresses adipogenic differentiation of multipotent mesenchymal progenitors. J Biol Chem 278: 45969-45977, 2003
    • (2003) J Biol Chem , vol.278 , pp. 45969-45977
    • Cheng, S.L.1    Shao, J.S.2    Charlton-Kachigian, N.3    Loewy, A.P.4    Towler, D.A.5
  • 34
    • 0031147795 scopus 로고    scopus 로고
    • Recombinant bone morphogenetic protein (BMP)-2 regulates costochondral growth plate chondrocytes and induces expression of BMP-2 and BMP-4 in a cell maturation-dependent manner
    • Erickson, DM, Harris SE, Dean DD, Harris MA, Wozney JM, Boyan BD, Schwartz Z: Recombinant bone morphogenetic protein (BMP)-2 regulates costochondral growth plate chondrocytes and induces expression of BMP-2 and BMP-4 in a cell maturation-dependent manner. J Orthop Res 15: 371-380, 1997
    • (1997) J Orthop Res , vol.15 , pp. 371-380
    • Erickson, D.M.1    Harris, S.E.2    Dean, D.D.3    Harris, M.A.4    Wozney, J.M.5    Boyan, B.D.6    Schwartz, Z.7
  • 36
    • 85190667435 scopus 로고    scopus 로고
    • Li X, Yang H-Y, Giachelli C: BMP-2 promotes phosphate uptake, phenotypic modulation, and calcification of vascular smooth muscle cells. Atherosclerosis 2008, doi: 10.1016/j.atherosclerosis.2007.11.031, in press
    • Li X, Yang H-Y, Giachelli C: BMP-2 promotes phosphate uptake, phenotypic modulation, and calcification of vascular smooth muscle cells. Atherosclerosis 2008, doi: 10.1016/j.atherosclerosis.2007.11.031, in press
  • 37
    • 0030056920 scopus 로고    scopus 로고
    • Human osteogenic protein-1 induces chondroblastic, osteoblastic, and/or adipocytic differentiation of clonal murine target cells
    • Asahina I, Sampath TK, Hauschka PV: Human osteogenic protein-1 induces chondroblastic, osteoblastic, and/or adipocytic differentiation of clonal murine target cells. Exp Cell Res 222: 38-47, 1996
    • (1996) Exp Cell Res , vol.222 , pp. 38-47
    • Asahina, I.1    Sampath, T.K.2    Hauschka, P.V.3
  • 39
    • 0034997337 scopus 로고    scopus 로고
    • BMP7 controls collecting tubule cell proliferation and apoptosis via Smad1-dependent and -independent pathways
    • Piscione TD, Phan T, Rosenblum ND: BMP7 controls collecting tubule cell proliferation and apoptosis via Smad1-dependent and -independent pathways. Am J Physiol Renal Physiol 280: F19-F33, 2001
    • (2001) Am J Physiol Renal Physiol , vol.280
    • Piscione, T.D.1    Phan, T.2    Rosenblum, N.D.3
  • 40
    • 0032475884 scopus 로고    scopus 로고
    • Specific activation of Srnad! signaling pathways by the BMP7 type I receptor, ALK2
    • Macias-Silva M, Hoodless PA, Tang SJ, Buchwald M, Wrana JL: Specific activation of Srnad! signaling pathways by the BMP7 type I receptor, ALK2. J Biol Chem 273: 25628-25636, 1998
    • (1998) J Biol Chem , vol.273 , pp. 25628-25636
    • Macias-Silva, M.1    Hoodless, P.A.2    Tang, S.J.3    Buchwald, M.4    Wrana, J.L.5
  • 41
    • 0028927556 scopus 로고
    • Two distinct osteoblast-specific cis acting elements control expression of a mouse osteocalcin gene
    • Ducy P, Karsenty G: Two distinct osteoblast-specific cis acting elements control expression of a mouse osteocalcin gene. Mol Cell Biol 15: 1858-1869, 1995
    • (1995) Mol Cell Biol , vol.15 , pp. 1858-1869
    • Ducy, P.1    Karsenty, G.2
  • 44
    • 28444468088 scopus 로고    scopus 로고
    • Wnt-dependent-ß-catenin signaling is activated after unilateral ureteral obstruction, and recombinant secreted frizzled-related protein 4 alters the progression of renal fibrosis
    • Surendran K, Schiavi S, Hruska KA: Wnt-dependent-ß-catenin signaling is activated after unilateral ureteral obstruction, and recombinant secreted frizzled-related protein 4 alters the progression of renal fibrosis. J Am Soc Nephrol 16: 2373-2384, 2005
    • (2005) J Am Soc Nephrol , vol.16 , pp. 2373-2384
    • Surendran, K.1    Schiavi, S.2    Hruska, K.A.3
  • 45
    • 0942301269 scopus 로고    scopus 로고
    • Vascular calcification in chronic kidney disease
    • Chen NX, Moe SM: Vascular calcification in chronic kidney disease. Semin Nephrol 24: 61-68, 2004
    • (2004) Semin Nephrol , vol.24 , pp. 61-68
    • Chen, N.X.1    Moe, S.M.2
  • 48
    • 12944328005 scopus 로고    scopus 로고
    • Phosphate is a specific signal for induction of osteopontin gene expression
    • Beck GR Jr, Zerler B, Moran E: Phosphate is a specific signal for induction of osteopontin gene expression. Proc Natl Acad Sci USA 97: 8352-8357, 2000
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 8352-8357
    • Beck Jr, G.R.1    Zerler, B.2    Moran, E.3
  • 50
    • 0036310682 scopus 로고    scopus 로고
    • Sevelamer attenuates the progression of coronary and aortic calcification in hemodialysis patients
    • Chertow GM, Burke SK, Raggi P: Sevelamer attenuates the progression of coronary and aortic calcification in hemodialysis patients. Kidney Int 62: 245-252, 2002
    • (2002) Kidney Int , vol.62 , pp. 245-252
    • Chertow, G.M.1    Burke, S.K.2    Raggi, P.3
  • 51
    • 31644446801 scopus 로고    scopus 로고
    • Effects of sevelamer and calcium on coronary artery calcification in patients new to hemodialysis
    • Block GA, Spiegel DM, Ehrlich J, Mehta R, Lindbergh J, Dreisbach A, Raggi P: Effects of sevelamer and calcium on coronary artery calcification in patients new to hemodialysis. Kidney Int 68: 1815-1824, 2005
    • (2005) Kidney Int , vol.68 , pp. 1815-1824
    • Block, G.A.1    Spiegel, D.M.2    Ehrlich, J.3    Mehta, R.4    Lindbergh, J.5    Dreisbach, A.6    Raggi, P.7


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