The human metapneumovirus matrix protein stimulates the inflammatory immune response In Vitro

PLoS ONE

Volumn 6, Issue 3, 2011, Pages

  Bagnaud Baule, Audrey ^a,b   Reynard, Olivier ^c   Perret, Magali ^b   Berland, Jean Luc ^b   Maache, Mimoun ^a   Peyrefitte, Christophe ^b,d   Vernet, Guy ^b   Volchkov, Viktor ^c   Paranhos Baccalà, Gláucia ^a,b  

^a BIOMÉRIEUX   (France)

^b Fondation Mérieux Laboratoire des Pathogènes Émergents   (France)

^c University Lyon i   (France)

^d INSTITUT DE RECHERCHE BIOMÉDICALE DES ARMÉES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD40 ANTIGEN; CD83 ANTIGEN; CD86 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 6; INTERLEUKIN 8; MATRIX PROTEIN; METAPNEUMOVIRUS MATRIX PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; AUTACOID; CD1 ANTIGEN; CD14 ANTIGEN; INTERFERON; T6 ANTIGEN;

ANTIGEN PRESENTING CELL; ARTICLE; CELL ACTIVATION; CELL STRAIN HEK293; CHILD; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; DISEASE COURSE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN METAPNEUMOVIRUS INFECTION; IMMUNE RESPONSE; IMMUNOMODULATION; IN VITRO STUDY; INFLAMMATION; MACROPHAGE ACTIVATION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN SYNTHESIS; WESTERN BLOTTING; ANTIGEN PRESENTATION; APOPTOSIS; BIOSYNTHESIS; CELL DIFFERENTIATION; CELL FRACTIONATION; CYTOLOGY; ENDOCYTOSIS; GENETIC TRANSFECTION; IMMUNITY; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; METAPNEUMOVIRUS; MONOCYTE; T LYMPHOCYTE; VIROLOGY;

HUMAN METAPNEUMOVIRUS; PARAMYXOVIRIDAE;

ANTIGEN PRESENTATION; ANTIGEN-PRESENTING CELLS; ANTIGENS, CD1; ANTIGENS, CD14; APOPTOSIS; CELL DIFFERENTIATION; DENDRITIC CELLS; ENDOCYTOSIS; HEK293 CELLS; HUMANS; IMMUNITY; INFLAMMATION; INFLAMMATION MEDIATORS; INTERFERONS; LYMPHOCYTE ACTIVATION; METAPNEUMOVIRUS; MONOCYTES; PROTEIN BINDING; SUBCELLULAR FRACTIONS; T-LYMPHOCYTES; TRANSFECTION; VIRAL MATRIX PROTEINS;

EID: 79952592250     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0017818     Document Type: Article

References (45)

1. van den Hoogen BG, de Jong JC, Groen J, Kuiken T, de Groot R, et al. (2001) A newly discovered human pneumovirus isolated from young children with respiratory tract disease. Nat Med 7: 719-724.
2. Principi N, Bosis S, Esposito S, (2006) Human metapneumovirus in paediatric patients. Clin Microbiol Infect 12: 301-308.
3. Williams JV, Harris PA, Tollefson SJ, Halburnt-Rush LL, Pingsterhaus JM, et al. (2004) Human metapneumovirus and lower respiratory tract disease in otherwise healthy infants and children. N Engl J Med 350: 443-450.
4. Boivin G, Abed Y, Pelletier G, Ruel L, Moisan D, et al. (2002) Virological features and clinical manifestations associated with human metapneumovirus: a new paramyxovirus responsible for acute respiratory-tract infections in all age groups. J Infect Dis 186: 1330-1334.
5. Greensill J, McNamara PS, Dove W, Flanagan B, Smyth RL, et al. (2003) Human metapneumovirus in severe respiratory syncytial virus bronchiolitis. Emerg Infect Dis 9: 372-375.
6. van den Hoogen BG, Osterhaus DM, Fouchier RA, (2004) Clinical impact and diagnosis of human metapneumovirus infection. Pediatr Infect Dis J 23: S25-32.
7. Kurt-Jones EA, Popova L, Kwinn L, Haynes LM, Jones LP, et al. (2000) Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. Nat Immunol 1: 398-401.
8. Martinez FD, Wright AL, Taussig LM, Holberg CJ, Halonen M, et al. (1995) Asthma and wheezing in the first six years of life. The Group Health Medical Associates. N Engl J Med 332: 133-138.
9. Zhang Y, Luxon BA, Casola A, Garofalo RP, Jamaluddin M, et al. (2001) Expression of respiratory syncytial virus-induced chemokine gene networks in lower airway epithelial cells revealed by cDNA microarrays. J Virol 75: 9044-9058.
10. Laham FR, Israele V, Casellas JM, Garcia AM, Lac Prugent CM, et al. (2004) Differential production of inflammatory cytokines in primary infection with human metapneumovirus and with other common respiratory viruses of infancy. J Infect Dis 189: 2047-2056.
11. Banchereau J, Steinman RM, (1998) Dendritic cells and the control of immunity. Nature 392: 245-252.
12. Grayson MH, Holtzman MJ, (2007) Emerging role of dendritic cells in respiratory viral infection. J Mol Med 85: 1057-1068.
13. Bilyk N, Holt PG, (1995) Cytokine modulation of the immunosuppressive phenotype of pulmonary alveolar macrophage populations. Immunology 86: 231-237.
14. van den Hoogen BG, Bestebroer TM, Osterhaus AD, Fouchier RA, (2002) Analysis of the genomic sequence of a human metapneumovirus. Virology 295: 119-132.
15. Takimoto T, Portner A, (2004) Molecular mechanism of paramyxovirus budding. Virus Res 106: 133-145.
16. Coronel EC, Takimoto T, Murti KG, Varich N, Portner A, (2001) Nucleocapsid incorporation into parainfluenza virus is regulated by specific interaction with matrix protein. J Virol 75: 1117-1123.
17. Kaptur PE, Rhodes RB, Lyles DS, (1991) Sequences of the vesicular stomatitis virus matrix protein involved in binding to nucleocapsids. J Virol 65: 1057-1065.
18. Lenard J, (1996) Negative-strand virus M and retrovirus MA proteins: all in a family? Virology 216: 289-298.
19. Latiff K, Meanger J, Mills J, Ghildyal R, (2004) Sequence and structure relatedness of matrix protein of human respiratory syncytial virus with matrix proteins of other negative-sense RNA viruses. Clin Microbiol Infect 10: 945-948.
20. Ghildyal R, Mills J, Murray M, Vardaxis N, Meanger J, (2002) Respiratory syncytial virus matrix protein associates with nucleocapsids in infected cells. J Gen Virol 83: 753-757.
21. Henderson G, Murray J, Yeo RP, (2002) Sorting of the respiratory syncytial virus matrix protein into detergent-resistant structures is dependent on cell-surface expression of the glycoproteins. Virology 300: 244-254.
22. Rodriguez L, Cuesta I, Asenjo A, Villanueva N, (2004) Human respiratory syncytial virus matrix protein is an RNA-binding protein: binding properties, location and identity of the RNA contact residues. J Gen Virol 85: 709-719.
23. Veyret R, Elaissari A, Marianneau P, Sall AA, Delair T, (2005) Magnetic colloids for the generic capture of viruses. Anal Biochem 346: 59-68.
24. Arribillaga L, de Cerio AL, Sarobe P, Casares N, Gorraiz M, et al. (2002) Vaccination with an adenoviral vector encoding hepatitis C virus (HCV) NS3 protein protects against infection with HCV-recombinant vaccinia virus. Vaccine 21: 202-210.
25. Graham FL, Smiley J, Russell WC, Nairn R, (1977) Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J Gen Virol 36: 59-74.
26. Duden R, (2003) ER-to-Golgi transport: COP I and COP II function (Review). Mol Membr Biol 20: 197-207.
27. Chang HC, Samaniego F, Nair BC, Buonaguro L, Ensoli B, (1997) HIV-1 Tat protein exits from cells via a leaderless secretory pathway and binds to extracellular matrix-associated heparan sulfate proteoglycans through its basic region. AIDS 11: 1421-1431.
28. Ensoli B, Buonaguro L, Barillari G, Fiorelli V, Gendelman R, et al. (1993) Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation. J Virol 67: 277-287.
29. Elliott G, O'Hare P, (1997) Intercellular trafficking and protein delivery by a herpesvirus structural protein. Cell 88: 223-233.
30. Nickel W, (2005) Unconventional secretory routes: direct protein export across the plasma membrane of mammalian cells. Traffic 6: 607-614.
31. Romagnani S, (1997) The Th1/Th2 paradigm. Immunol Today 18: 263-266.
32. Taub DD, Oppenheim JJ, (1994) Chemokines, inflammation and the immune system. Ther Immunol 1: 229-246.
33. Taub DD, Ortaldo JR, Turcovski-Corrales SM, Key ML, Longo DL, et al. (1996) Beta chemokines costimulate lymphocyte cytolysis, proliferation, and lymphokine production. J Leukoc Biol 59: 81-89.
34. Baggiolini M, Dewald B, Moser B, (1994) Interleukin-8 and related chemotactic cytokines-CXC and CC chemokines. Adv Immunol 55: 97-179.
35. Moser B, Loetscher P, (2001) Lymphocyte traffic control by chemokines. Nat Immunol 2: 123-128.
36. Boivin G, De Serres G, Hamelin ME, Cote S, Argouin M, et al. (2007) An outbreak of severe respiratory tract infection due to human metapneumovirus in a long-term care facility. Clin Infect Dis 44: 1152-1158.
37. Schroder K, Hertzog PJ, Ravasi T, Hume DA, (2004) Interferon-gamma: an overview of signals, mechanisms and functions. J Leukoc Biol 75: 163-189.
38. Stetson DB, Medzhitov R, (2006) Type I interferons in host defense. Immunity 25: 373-381.
39. Guerrero-Plata A, Casola A, Suarez G, Yu X, Spetch L, et al. (2006) Differential response of dendritic cells to human metapneumovirus and respiratory syncytial virus. Am J Respir Cell Mol Biol 34: 320-329.
40. Spann KM, Tran KC, Chi B, Rabin RL, Collins PL, (2004) Suppression of the induction of alpha, beta, and lambda interferons by the NS1 and NS2 proteins of human respiratory syncytial virus in human epithelial cells and macrophages [corrected]. J Virol 78: 4363-4369.
41. Bao X, Liu T, Shan Y, Li K, Garofalo RP, et al. (2008) Human metapneumovirus glycoprotein G inhibits innate immune responses. PLoS Pathog 4: e1000077.
42. Tan MC, Battini L, Tuyama AC, Macip S, Melendi GA, et al. (2007) Characterization of human metapneumovirus infection of myeloid dendritic cells. Virology 357: 1-9.
43. de Graaff PM, de Jong EC, van Capel TM, van Dijk ME, Roholl PJ, et al. (2005) Respiratory syncytial virus infection of monocyte-derived dendritic cells decreases their capacity to activate CD4 T cells. J Immunol 175: 5904-5911.
44. Wilkesmann A, Schildgen O, Eis-Hubinger AM, Geikowski T, Glatzel T, et al. (2006) Human metapneumovirus infections cause similar symptoms and clinical severity as respiratory syncytial virus infections. Eur J Pediatr 165: 467-475.
45. Boivin G, De Serres G, Cote S, Gilca R, Abed Y, et al. (2003) Human metapneumovirus infections in hospitalized children. Emerg Infect Dis 9: 634-640.