Re-assembled casein micelles and casein nanoparticles as nano-vehicles for ω-3 polyunsaturated fatty acids

Food Hydrocolloids

Volumn 25, Issue 5, 2011, Pages 1270-1276

  Zimet, Patricia ^a   Rosenberg, Dina ^a   Livney, Yoav D ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

Casein; Casein micelles; DHA; Nanoencapsulation; Nutraceuticals; Omega 3

Indexed keywords

BIOCHEMISTRY; MICELLES; MOLECULES; NANOPARTICLES; PARTICLE SIZE; POLYUNSATURATED FATTY ACIDS; SELF ASSEMBLY;

BIOACTIVES; BIOLOGICAL FUNCTIONS; CASEIN MICELLES; DOCOSAHEXAENOIC ACID; MILK PROTEIN; NANO-ENCAPSULATION; NUTRACEUTICALS; OMEGA-3; OMEGA-3 POLYUNSATURATED FATTY ACIDS; PROPERTY;

CASEIN;

HARNESS;

EID: 79952539269     PISSN: 0268005X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.foodhyd.2010.11.025     Document Type: Article

References (33)

1. Almajano M.P., Delgado M.E., Gordon M.H. Changes in the antioxidant properties of protein solutions in the presence of epigallocatechin gallate. Food Chemistry 2007, 101(1):126-130.
2. Arts M.J.T.J., Haenen G.R.M.M., Wilms L.C., Beetstra S.A.J.N., Heijnen C.G.M., Voss H.P., et al. Interactions between flavonoids and proteins: effect on the total antioxidant capacity. Journal of Agricultural and Food Chemistry 2002, 50(5):1184-1187.
3. Berquin I.M., Edwards I.J., Chen Y.Q. Multi-targeted therapy of cancer by omega-3 fatty acids. Cancer Letters 2008, 269(2):363-377.
4. Beydoun M.A., Kaufman J.S., Satia J.A., Rosamond W., Folsom A.R. Plasma n-3 fatty acids and the risk of cognitive decline in older adults: the Atherosclerosis Risk in Communities Study. American Journal of Clinical Nutrition 2007, 85(4):1103-1111.
5. Bhattacharya A., Rahman M., Sun D., Fernandes G. Effect of fish oil on bone mineral density in aging C57BL/6 female mice. Journal of Nutritional Biochemistry 2007, 18(6):372-379.
6. Cogan U., Kopelman M., Mokady S., Shinitzky M. Binding affinities of retinol and related compounds to retinol binding proteins. European Journal of Biochemistry 1976, 65(1):71-78.
7. Fox P.F. Milk proteins: general and historical aspects. Proteins, Part A 2003, Vol. 1:1-48. Kluwer Academic/Plenum Publishers, New York. 3rd ed. P.F. Fox, P.L.H. McSweeney (Eds.).
8. Fox P.F., Brodkorb A. The casein micelle: historical aspects, current concepts and significance. International Dairy Journal 2008, 18(7):677-684.
9. van Gelder B.M., Tijhuis M., Kalmijn S., Kromhout D. Fish consumption, n-3 fatty acids, and subsequent 5-y cognitive decline in elderly men: the Zutphen Elderly Study. American Journal of Clinical Nutrition 2007, 85(4):1142-1147.
10. Gudipati V., Sandra S., McClements D.J., Decker E.A. Oxidative stability and in vitro digestibility of fish oil-in-water emulsions containing multilayered membranes. Journal of Agricultural and Food Chemistry 2010, 58(13):8093-8099.
11. 2 Study. American Journal of Clinical Nutrition 2007, 85:803-807.
12. Horne D.S. Casein micelles as hard spheres: limitations of the model in acidified gel formation. Colloids and Surfaces A: Physicochemical and Engineering Aspects 2003, 213(2-3):255-263.
13. Jakobsson M., Sivik B. Oxidative stability of fish-oil included in a microemulsion. Journal of Dispersion Science and Technology 1994, 15(5):611-619.
14. Knoh D., Livney Y.D. Nanoencapsulation of hydrophobic nutraceuticals within self reassembled casein micelles. Delivery of functionality in complex food systems conference 2007, University of Massachusetts, Amherst, Massachusetts, USA.
15. Knoop A.M., Knoop E., Wiechen A. Sub-structure of synthetic casein micelles. Journal of Dairy Research 1979, 46(2):347-350. Proc. IDF Symp. Phys. Chem. Milk Proteins.
16. Kosaraju S.L., Weerakkody R., Augustin M.A. In-vitro evaluation of hydrocolloid-based encapsulated fish oil. Food Hydrocolloids 2009, 23(5):1413-1419.
17. de Kruif C.G., Grinberg V.Y. Micellisation of beta-casein. Colloids and Surfaces A: Physicochemical and Engineering Aspects 2002, 210(2-3):183-190.
18. de Kruif C.G., Holt C. Casein micelle structure, functions and interactions. Proteins, Part A 2003, Vol. 1:233-276. Kluwer Academic/Plenum Publishers, New York. 3rd ed. P.F. Fox, P.L.H. McSweeney (Eds.).
19. Liu Y., Guo R. pH-dependent structures and properties of casein micelles. Biophysical Chemistry 2008, 136(2-3):67-73.
20. Livney Y.D. Milk proteins as vehicles for bioactives. Current Opinion in Colloid & Interface Science 2010, 15(1-2):73-83.
21. Lopez-Huertas E. Health effects of oleic acid and long chain omega-3 fatty acids (EPA and DHA) enriched milks. A review of intervention studies. Pharmacological Research 2010, 61(3):200-207.
22. McMahon D.J., McManus W.R. Rethinking casein micelle structure using electron microscopy. Journal of Dairy Science 1998, 81(11):2985-2993.
23. Portnaya I., Cogan U., Livney Y.D., Ramon O., Shimoni K., Rosenberg M., et al. Micellization of bovine beta casein studied by isothermal titration microcalorimetry and cryogenic transmission electron microscopy. Journal of Agricultural and Food Chemistry 2006, 54(15):5555-5561.
24. Ruxton C.H., Calder P.C., Reed S.C., Simpson M.J. The impact of long-chain n-3 polyunsaturated fatty acids on human health. Nutrition Research Reviews 2005, 18(1):113-129.
25. Semo E., Kesselman E., Danino D., Livney Y.D. Casein micelle as a natural nano-capsular vehicle for nutraceuticals. Food Hydrocolloids 2007, 21(5-6):936-942.
26. Serth J., Lautwein A., Frech M., Wittinghofer A., Pingoud A. The inhibition of the GTPase activating protein-Ha-ras interaction by acidic lipids is due to physical association of the C-terminal domain of the GTPase activating protein with micellar structures. EMBO Journal 1991, 10(6):1325-1330.
27. Shapira A., Assaraf Y.G., Livney Y.D. Beta-casein nano-vehicles for oral delivery of chemotherapeutic drugs. Nanomedicine: Nanotechnology, Biology, and Medicine 2010, 6:119-126.
28. Swaisgood H.E. Chemistry of the caseins. Proteins, Part A 2003, Vol. 1:139-201. Kluwer Academic/Plenum Publishers, New York. 3rd ed. P.F. Fox, P.L.H. McSweeney (Eds.).
29. Walstra P. On the stability of casein micelles. Journal of Dairy Research 1990, 73(8):1965-1979.
30. Yashodhara B.M., Umakanth S., Pappachan J.M., Bhat S.K., Kamath R., Choo B.H. Omega-3 fatty acids: a comprehensive review of their role in health and disease. Postgraduate Medical Journal 2009, 85(1000):84-90.
31. Zabar S., Lesmes U., Katz I., Shimoni E., Bianco-Peled H. Structural characterization of amylose-long chain fatty acid complexes produced via the acidification method. Food Hydrocolloids 2010, 24(4):347-357.
32. Zhang W., Yan C., May J., Barrow C.J. Whey protein and gum Arabic encapsulated omega-3 lipids the effect of material properties on coacervation. Agro Food Industry Hi-Tech 2009, 20(4):18-21.
33. Zimet P., Livney Y.D. Beta-lactoglobulin and its nanocomplexes with pectin as vehicles for omega-3 polyunsaturated fatty acids. Food Hydrocolloids 2009, 23(4):1120-1126.