NF-κB-mediated anti-inflammatory activity of the sesquiterpene lactone 7-hydroxyfrullanolide

European Journal of Pharmacology

Volumn 657, Issue 1-3, 2011, Pages 41-50

  Fonseca, Lyle C ^a   Dadarkar, Shruta S ^a   Lobo, Aurelio S ^a   Mishra, Prabha B ^a   Thakkar, Arvind D ^a   Chandrababu, Shanthi ^b   Padigaru, Muralidhara ^a  

^a Piramal Enterprises Limited   (India)

^b VIT UNIVERSITY   (India)

Author keywords

Adhesion molecules; Inflammation; Microarray; Sesquiterpene lactone

Indexed keywords

7 HYDROXYFRULLANOLIDE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; SESQUITERPENE LACTONE DERIVATIVE; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ADHESION; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG STRUCTURE; ENDOTHELIUM CELL; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; MONOCYTE; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RHEUMATOID ARTHRITIS; SYNOVIOCYTE;

ANTI-INFLAMMATORY AGENTS; ARTHRITIS, RHEUMATOID; CELL ADHESION; CELL ADHESION MOLECULES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENDOTHELIAL CELLS; GENE EXPRESSION PROFILING; HUMANS; I-KAPPA B KINASE; INFLAMMATION; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; MONOCYTES; NF-KAPPA B; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHOSPHORYLATION; PROTEIN TRANSPORT; RNA, MESSENGER; SESQUITERPENES; SYNOVIAL FLUID;

EID: 79952488730     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.01.050     Document Type: Article

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