-
1
-
-
38449117722
-
Autosomal recessive PKD in the early years
-
Guay-Woodford L.M. Autosomal recessive PKD in the early years. Nephrol News Issues 2007, 21:39.
-
(2007)
Nephrol News Issues
, vol.21
, pp. 39
-
-
Guay-Woodford, L.M.1
-
2
-
-
33746655404
-
Autosomal recessive polycystic kidney disease and congenital hepatic fibrosis: summary statement of a first National Institutes of Health/Office of Rare Diseases conference
-
Gunay-Aygun M., Avner E.D., Bacallao R.L., Choyke P.L., Flynn J.T., Germino G.G., Guay-Woodford L., Harris P., Heller T., Ingelfinger J., Kaskel F., Kleta R., LaRusso N.F., Mohan P., Pazour G.J., Shneider B.L., Torres V.E., Wilson P., Zak C., Zhou J., Gahl W.A. Autosomal recessive polycystic kidney disease and congenital hepatic fibrosis: summary statement of a first National Institutes of Health/Office of Rare Diseases conference. J. Pediatr. 2006, 149:159-164.
-
(2006)
J. Pediatr.
, vol.149
, pp. 159-164
-
-
Gunay-Aygun, M.1
Avner, E.D.2
Bacallao, R.L.3
Choyke, P.L.4
Flynn, J.T.5
Germino, G.G.6
Guay-Woodford, L.7
Harris, P.8
Heller, T.9
Ingelfinger, J.10
Kaskel, F.11
Kleta, R.12
LaRusso, N.F.13
Mohan, P.14
Pazour, G.J.15
Shneider, B.L.16
Torres, V.E.17
Wilson, P.18
Zak, C.19
Zhou, J.20
Gahl, W.A.21
more..
-
3
-
-
34147215806
-
Fibrocystin/polyductin, found in the same protein complex with polycystin-2, regulates calcium responses in kidney epithelia
-
Wang S., Zhang J., Nauli S.M., Li X., Starremans P.G., Luo Y., Roberts K.A., Zhou J. Fibrocystin/polyductin, found in the same protein complex with polycystin-2, regulates calcium responses in kidney epithelia. Mol. Cell. Biol. 2007, 27:3241-3252.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 3241-3252
-
-
Wang, S.1
Zhang, J.2
Nauli, S.M.3
Li, X.4
Starremans, P.G.5
Luo, Y.6
Roberts, K.A.7
Zhou, J.8
-
4
-
-
0036509712
-
The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein
-
Ward C.J., Hogan M.C., Rossetti S., Walker D., Sneddon T., Wang X., Kubly V., Cunningham J.M., Bacallao R., Ishibashi M., Milliner D.S., Torres V.E., Harris P.C. The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein. Nat. Genet. 2002, 30:259-269.
-
(2002)
Nat. Genet.
, vol.30
, pp. 259-269
-
-
Ward, C.J.1
Hogan, M.C.2
Rossetti, S.3
Walker, D.4
Sneddon, T.5
Wang, X.6
Kubly, V.7
Cunningham, J.M.8
Bacallao, R.9
Ishibashi, M.10
Milliner, D.S.11
Torres, V.E.12
Harris, P.C.13
-
5
-
-
18344366124
-
PKHD1, the polycystic kidney and hepatic disease 1 gene, encodes a novel large protein containing multiple immunoglobulin-like plexin-transcription-factor domains and parallel beta-helix 1 repeats
-
Onuchic L.F., Furu L., Nagasawa Y., Hou X., Eggermann T., Ren Z., Bergmann C., Senderek J., Esquivel E., Zeltner R., Rudnik-Schoneborn S., Mrug M., Sweeney W., Avner E.D., Zerres K., Guay-Woodford L.M., Somlo S., Germino G.G. PKHD1, the polycystic kidney and hepatic disease 1 gene, encodes a novel large protein containing multiple immunoglobulin-like plexin-transcription-factor domains and parallel beta-helix 1 repeats. Am. J. Hum. Genet. 2002, 70:1305-1317.
-
(2002)
Am. J. Hum. Genet.
, vol.70
, pp. 1305-1317
-
-
Onuchic, L.F.1
Furu, L.2
Nagasawa, Y.3
Hou, X.4
Eggermann, T.5
Ren, Z.6
Bergmann, C.7
Senderek, J.8
Esquivel, E.9
Zeltner, R.10
Rudnik-Schoneborn, S.11
Mrug, M.12
Sweeney, W.13
Avner, E.D.14
Zerres, K.15
Guay-Woodford, L.M.16
Somlo, S.17
Germino, G.G.18
-
7
-
-
33749244433
-
Molecular and cellular pathophysiology of autosomal recessive polycystic kidney disease (ARPKD)
-
Jr Sweeney W.E., Avner E.D. Molecular and cellular pathophysiology of autosomal recessive polycystic kidney disease (ARPKD). Cell Tissue Res. 2006, 326:671-685.
-
(2006)
Cell Tissue Res.
, vol.326
, pp. 671-685
-
-
Jr Sweeney, W.E.1
Avner, E.D.2
-
8
-
-
33751532426
-
Mutations in the inter-SH2 domain of the regulatory subunit of phosphoinositide 3-kinase: effects on catalytic subunit binding and holoenzyme function
-
Elis W., Lessmann E., Oelgeschlager M., Huber M. Mutations in the inter-SH2 domain of the regulatory subunit of phosphoinositide 3-kinase: effects on catalytic subunit binding and holoenzyme function. Biol. Chem. 2006, 387:1567-1573.
-
(2006)
Biol. Chem.
, vol.387
, pp. 1567-1573
-
-
Elis, W.1
Lessmann, E.2
Oelgeschlager, M.3
Huber, M.4
-
9
-
-
34247139703
-
Regulation of class IA PI3Ks: is there a role for monomeric PI3K subunits
-
Geering B., Cutillas P.R., Vanhaesebroeck B. Regulation of class IA PI3Ks: is there a role for monomeric PI3K subunits. Biochem. Soc. Trans. 2007, 35:199-203.
-
(2007)
Biochem. Soc. Trans.
, vol.35
, pp. 199-203
-
-
Geering, B.1
Cutillas, P.R.2
Vanhaesebroeck, B.3
-
10
-
-
0033852193
-
Receptor isoforms mediate opposing proliferative effects through gbetagamma-activated p38 or Akt pathways
-
Sellers L.A., Alderton F., Carruthers A.M., Schindler M., Humphrey P.P. Receptor isoforms mediate opposing proliferative effects through gbetagamma-activated p38 or Akt pathways. Mol. Cell. Biol. 2000, 20:5974-5985.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 5974-5985
-
-
Sellers, L.A.1
Alderton, F.2
Carruthers, A.M.3
Schindler, M.4
Humphrey, P.P.5
-
11
-
-
54349128159
-
Miyabenol A inhibits LPS-induced NO production via IKK/IkappaB inactivation in RAW 264.7 macrophages: possible involvement of the p38 and PI3K pathways
-
Ku K.T., Huang Y.L., Huang Y.J., Chiou W.F. Miyabenol A inhibits LPS-induced NO production via IKK/IkappaB inactivation in RAW 264.7 macrophages: possible involvement of the p38 and PI3K pathways. J. Agric. Food Chem. 2008, 56:8911-8918.
-
(2008)
J. Agric. Food Chem.
, vol.56
, pp. 8911-8918
-
-
Ku, K.T.1
Huang, Y.L.2
Huang, Y.J.3
Chiou, W.F.4
-
12
-
-
0036185848
-
The protein kinase B/Akt signaling pathway in human malignancy
-
Nicholson K.M., Anderson N.G. The protein kinase B/Akt signaling pathway in human malignancy. Cell Signal. 2002, 14:381-395.
-
(2002)
Cell Signal.
, vol.14
, pp. 381-395
-
-
Nicholson, K.M.1
Anderson, N.G.2
-
13
-
-
62449233322
-
NFkappaB signaling in carcinogenesis and as a potential molecular target for cancer therapy
-
Shen H.M., Tergaonkar V. NFkappaB signaling in carcinogenesis and as a potential molecular target for cancer therapy. Apoptosis 2009, 14:348-363.
-
(2009)
Apoptosis
, vol.14
, pp. 348-363
-
-
Shen, H.M.1
Tergaonkar, V.2
-
14
-
-
0029999656
-
Bcl-2 down-regulates the activity of transcription factor NF-kappaB induced upon apoptosis
-
Grimm S., Bauer M.K., Baeuerle P.A., Schulze-Osthoff K. Bcl-2 down-regulates the activity of transcription factor NF-kappaB induced upon apoptosis. J. Cell Biol. 1996, 134:13-23.
-
(1996)
J. Cell Biol.
, vol.134
, pp. 13-23
-
-
Grimm, S.1
Bauer, M.K.2
Baeuerle, P.A.3
Schulze-Osthoff, K.4
-
15
-
-
68949207750
-
Inhibition of PKHD1 may cause S-phase entry via mTOR signaling pathway
-
Zheng R., Wang L., Fan J., Zhou Q. Inhibition of PKHD1 may cause S-phase entry via mTOR signaling pathway. Cell Biol. Int. 2009, 33:926-933.
-
(2009)
Cell Biol. Int.
, vol.33
, pp. 926-933
-
-
Zheng, R.1
Wang, L.2
Fan, J.3
Zhou, Q.4
-
16
-
-
54949109808
-
PI3K/Akt: getting it right matters
-
Franke T.F. PI3K/Akt: getting it right matters. Oncogene 2008, 27:6473-6488.
-
(2008)
Oncogene
, vol.27
, pp. 6473-6488
-
-
Franke, T.F.1
-
17
-
-
0036430574
-
Survival signaling in type II pneumocytes activated by surfactant protein-A
-
White M.K., Strayer D.S. Survival signaling in type II pneumocytes activated by surfactant protein-A. Exp Cell Res. 2002, 280:270-279.
-
(2002)
Exp Cell Res.
, vol.280
, pp. 270-279
-
-
White, M.K.1
Strayer, D.S.2
-
18
-
-
47749124551
-
Pathways of apoptosis in human autosomal recessive and autosomal dominant polycystic kidney diseases
-
Goilav B., Satlin L.M., Wilson P.D. Pathways of apoptosis in human autosomal recessive and autosomal dominant polycystic kidney diseases. Pediatr. Nephrol. 2008, 23:1473-1482.
-
(2008)
Pediatr. Nephrol.
, vol.23
, pp. 1473-1482
-
-
Goilav, B.1
Satlin, L.M.2
Wilson, P.D.3
-
19
-
-
27744473165
-
Fibrocystin interacts with CAML, a protein involved in Ca2+ signaling
-
Nagano J., Kitamura K., Hujer K.M., Ward C.J., Bram R.J., Hopfer U., Tomita K., Huang C., Miller R.T. Fibrocystin interacts with CAML, a protein involved in Ca2+ signaling. Biochem. Biophys. Res. Commun. 2005, 338:880-889.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.338
, pp. 880-889
-
-
Nagano, J.1
Kitamura, K.2
Hujer, K.M.3
Ward, C.J.4
Bram, R.J.5
Hopfer, U.6
Tomita, K.7
Huang, C.8
Miller, R.T.9
-
20
-
-
0037059760
-
A new role for the p85-phosphatidylinositol 3-kinase regulatory subunit linking FRAP to p70 S6 kinase activation
-
Gonzalez-Garcia A., Garrido E., Hernandez C., Alvarez B., Jimenez C., Cantrell D.A., Pullen N., Carrera A.C. A new role for the p85-phosphatidylinositol 3-kinase regulatory subunit linking FRAP to p70 S6 kinase activation. J. Biol. Chem. 2002, 277:1500-1508.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 1500-1508
-
-
Gonzalez-Garcia, A.1
Garrido, E.2
Hernandez, C.3
Alvarez, B.4
Jimenez, C.5
Cantrell, D.A.6
Pullen, N.7
Carrera, A.C.8
-
21
-
-
34250788809
-
AKT/PKB signaling: navigating downstream
-
Manning B.D., Cantley L.C. AKT/PKB signaling: navigating downstream. Cell 2007, 129:1261-1274.
-
(2007)
Cell
, vol.129
, pp. 1261-1274
-
-
Manning, B.D.1
Cantley, L.C.2
-
22
-
-
34250729007
-
Mitochondrial permeability transition pore opening as an endpoint to initiate cell death and as a putative target for cardioprotection
-
Javadov S., Karmazyn M. Mitochondrial permeability transition pore opening as an endpoint to initiate cell death and as a putative target for cardioprotection. Cell Physiol Biochem. 2007, 20:1-22.
-
(2007)
Cell Physiol Biochem.
, vol.20
, pp. 1-22
-
-
Javadov, S.1
Karmazyn, M.2
-
23
-
-
0028102478
-
Cleavage of poly (ADP-ribose) polymerase by a proteinase with properties like ICE
-
Lazebnik Y.A., Kaufmann S.H., Desnoyers S., Poirier G.G., Earnshaw W.C. Cleavage of poly (ADP-ribose) polymerase by a proteinase with properties like ICE. Nature 1994, 371:346-347.
-
(1994)
Nature
, vol.371
, pp. 346-347
-
-
Lazebnik, Y.A.1
Kaufmann, S.H.2
Desnoyers, S.3
Poirier, G.G.4
Earnshaw, W.C.5
-
24
-
-
8444248231
-
Nuclear factor kappaB activity determines the sensitivity of kidney epithelial cells to apoptosis: implications for mercury-induced renal failure
-
Dieguez-Acuna F.J., Polk W.W., Ellis M.E., Simmonds P.L., Kushleika J.V., Woods J.S. Nuclear factor kappaB activity determines the sensitivity of kidney epithelial cells to apoptosis: implications for mercury-induced renal failure. Toxicol Sci. 2004, 82:114-123.
-
(2004)
Toxicol Sci.
, vol.82
, pp. 114-123
-
-
Dieguez-Acuna, F.J.1
Polk, W.W.2
Ellis, M.E.3
Simmonds, P.L.4
Kushleika, J.V.5
Woods, J.S.6
-
25
-
-
60949101118
-
Involvement of intracellular signaling cascades in inflammatory responses in human intestinal epithelial cells following Vibrio cholerae infection
-
Bandyopadhaya A., Das D., Chaudhuri K. Involvement of intracellular signaling cascades in inflammatory responses in human intestinal epithelial cells following Vibrio cholerae infection. Mol. Immunol. 2009, 46:1129-1139.
-
(2009)
Mol. Immunol.
, vol.46
, pp. 1129-1139
-
-
Bandyopadhaya, A.1
Das, D.2
Chaudhuri, K.3
-
26
-
-
27144459692
-
Phosphorylation of RelA/p65 on serine 536 defines an I{kappa}B{alpha}-independent NF-{kappa}B pathway
-
Sasaki C.Y., Barberi T.J., Ghosh P., Longo D.L. Phosphorylation of RelA/p65 on serine 536 defines an I{kappa}B{alpha}-independent NF-{kappa}B pathway. J. Biol. Chem. 2005, 280:34538-34547.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 34538-34547
-
-
Sasaki, C.Y.1
Barberi, T.J.2
Ghosh, P.3
Longo, D.L.4
-
27
-
-
33644506745
-
Lipopolysaccharide-induced production of interleukin-10 is promoted by the serine/threonine kinase Akt
-
Pengal R.A., Ganesan L.P., Wei G., Fang H., Ostrowski M.C., Tridandapani S. Lipopolysaccharide-induced production of interleukin-10 is promoted by the serine/threonine kinase Akt. Mol. Immunol. 2006, 43:1557-1564.
-
(2006)
Mol. Immunol.
, vol.43
, pp. 1557-1564
-
-
Pengal, R.A.1
Ganesan, L.P.2
Wei, G.3
Fang, H.4
Ostrowski, M.C.5
Tridandapani, S.6
-
28
-
-
34548295887
-
Endothelial NF-kappaB as a mediator of kidney damage: the missing link between systemic vascular and renal disease?
-
Guzik T.J., Harrison D.G. Endothelial NF-kappaB as a mediator of kidney damage: the missing link between systemic vascular and renal disease?. Circ. Res. 2007, 101:227-229.
-
(2007)
Circ. Res.
, vol.101
, pp. 227-229
-
-
Guzik, T.J.1
Harrison, D.G.2
-
29
-
-
0034689773
-
Role of NF-kappaB in p53-mediated programmed cell death
-
Ryan K.M., Ernst M.K., Rice N.R., Vousden K.H. Role of NF-kappaB in p53-mediated programmed cell death. Nature 2000, 404:892-897.
-
(2000)
Nature
, vol.404
, pp. 892-897
-
-
Ryan, K.M.1
Ernst, M.K.2
Rice, N.R.3
Vousden, K.H.4
-
30
-
-
34247329078
-
Just the right amount of JNK - how NF-κB and downstream mediators prevent burn-induced intestinal injury
-
Clark J.A., Coopersmith C.M. Just the right amount of JNK - how NF-κB and downstream mediators prevent burn-induced intestinal injury. Crit Care Med. 2007, 1433-1434.
-
(2007)
Crit Care Med.
, pp. 1433-1434
-
-
Clark, J.A.1
Coopersmith, C.M.2
-
31
-
-
62849114121
-
Leptin exerts an anti-apoptotic effect on human dendritic cells via the PI3K-Akt signaling pathway
-
Mattioli B., Giordani L., Quaranta M.G., Viora M. Leptin exerts an anti-apoptotic effect on human dendritic cells via the PI3K-Akt signaling pathway. FEBS Lett. 2009, 583:1102-1106.
-
(2009)
FEBS Lett.
, vol.583
, pp. 1102-1106
-
-
Mattioli, B.1
Giordani, L.2
Quaranta, M.G.3
Viora, M.4
|