Sindbis virus replication, is insensitive to rapamycin and torin1, and suppresses Akt/mTOR pathway late during infection in HEK cells

Biochemical and Biophysical Research Communications

Volumn 406, Issue 2, 2011, Pages 262-267

  Mohankumar, Vidyarani ^a   Dhanushkodi, Nisha R ^a   Raju, Ramaswamy ^a  

^a MEHARRY MEDICAL COLLEGE   (United States)

Author keywords

Akt mTOR; Rapamycin; Sindbis; Torin1; Translation

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; INITIATION FACTOR 4E BINDING PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RAPAMYCIN; S6 KINASE; TORIN1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ELF2ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; HUMAN; HUMAN CELL; NONHUMAN; ONCOLYTIC VIROTHERAPY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; SINDBIS VIRUS; TRANSLATION REGULATION; VIRUS INFECTION; VIRUS RELEASE; VIRUS REPLICATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CHROMONES; GENETIC ENGINEERING; HEK293 CELLS; HUMANS; MORPHOLINES; NAPHTHYRIDINES; ONCOLYTIC VIRUSES; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHOPROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RIBOSOMAL PROTEIN S6 KINASES; SINDBIS VIRUS; SIROLIMUS; TOR SERINE-THREONINE KINASES; VIRUS REPLICATION;

SINDBIS VIRUS;

EID: 79952443480     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.02.030     Document Type: Article

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