Suppression of mitochondrial NADP+-dependent isocitrate dehydrogenase activity enhances curcumin-induced apoptosis in HCT116 cells

Free Radical Research

Volumn 45, Issue 4, 2011, Pages 431-438

  Jung, Kyu Ho ^a   Park, Jeen Woo ^a  

^a Kyungpook National University   (South Korea)

Author keywords

Antioxidant enzyme; apoptosis; curcumin; redox status; siRNA

Indexed keywords

CURCUMIN; ISOCITRATE DEHYDROGENASE (NADP); NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SMALL INTERFERING RNA;

APOPTOSIS; ARTICLE; CELL STRAIN HCT116; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA FRAGMENTATION; ENZYME ACTIVITY; IN VITRO GENE TRANSFER; OXIDATION REDUCTION STATE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; CURCUMIN; DNA FRAGMENTATION; DRUG SYNERGISM; ESCHERICHIA COLI; HCT116 CELLS; HELA CELLS; HUMANS; ISOCITRATE DEHYDROGENASE; MITOCHONDRIA; MUTAGENESIS, SITE-DIRECTED; NADP; NEOPLASMS; OXIDATION-REDUCTION; OXIDATIVE STRESS; RECOMBINANT PROTEINS; RNA, SMALL INTERFERING; TRANSFECTION;

CURCUMA LONGA;

EID: 79952418453     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.3109/10715762.2010.540574     Document Type: Article

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