Small interfering RNA-mediated silencing of mitochondrial NADP+-dependent isocitrate dehydrogenase enhances the sensitivity of HeLa cells toward tumor necrosis factor-α and anticancer drugs

Free Radical Biology and Medicine

Volumn 43, Issue 8, 2007, Pages 1197-1207

  Kil, In Sup ^a   Kim, Sung Youl ^a   Lee, Sun Joo ^a   Park, Jeen Woo ^a  

^a Kyungpook National University   (South Korea)

Author keywords

Antioxidant enzyme; Apoptosis; Free radicals; Mitochondria; Redox status; siRNA

Indexed keywords

ANTINEOPLASTIC AGENT; DACTINOMYCIN; DNA FRAGMENT; DOXORUBICIN; ETOPOSIDE; ISOCITRATE DEHYDROGENASE; SMALL INTERFERING RNA; STAUROSPORINE; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CONTROLLED STUDY; DRUG SENSITIVITY; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; HELA CELL; HUMAN; HUMAN CELL; MITOCHONDRION; MORPHOLOGY; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN FUNCTION; SENSITIVITY ANALYSIS;

ANTINEOPLASTIC AGENTS; APOPTOSIS; HELA CELLS; HUMANS; ISOCITRATE DEHYDROGENASE; MITOCHONDRIA; RNA, SMALL INTERFERING; STAUROSPORINE; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 34548502694     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2007.07.009     Document Type: Article

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