Microemulsions for topical use- A review

Indian Journal of Pharmaceutical Education and Research

Volumn 45, Issue 1, 2011, Pages 100-107

  Grampurohit, Nirmala ^a   Ravikumar, Padmini ^a   Mallya, Rashmi ^a  

^a SVKM S DR BHANUBEN NANAVATI COLLEGE OF PHARMACY   (India)

Author keywords

Antioxidant; Co surfactant; Microemulsion; Topical delivery

Indexed keywords

ACICLOVIR; ALPHA TOCOPHEROL; ANTI ACNE AGENT; ANTIOXIDANT; ASCORBIC ACID; ASCORBYL PALMITATE; AZELAIC ACID; CELECOXIB; CLOTRIMAZOLE; COSMETIC; CYCLOOXYGENASE 2 INHIBITOR; CYCLOSPORIN A; EYE DROPS; FLUCONAZOLE; FUROCOUMARIN; ITRACONAZOLE; KETOCONAZOLE; LIPOXYGENASE INHIBITOR; METHOXSALEN; MICONAZOLE; PENCICLOVIR; PSORALEA CORYLIFOLIA EXTRACT; PSORALEN; RETINOIC ACID; SPERMICIDAL AGENT; TEMOZOLOMIDE; ZILEUTON;

ACNE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; AUTOIMMUNE SKIN DISEASE; CANCER COMBINATION CHEMOTHERAPY; CREAM; DISEASE CLASSIFICATION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG EFFICACY; DRUG FORMULATION; DRUG MANUFACTURE; DRUG PENETRATION; DRUG POTENCY; DRUG SAFETY; DRUG SOLUBILITY; DRUG STABILITY; ECZEMA; HERPES SIMPLEX; HUMAN; HYDROGEL; MICROEMULSION; MYCOSIS; NONHUMAN; OINTMENT; PSORIASIS; SKIN CANCER; SKIN DEFECT; SKIN DISEASE; SKIN INFLAMMATION; SUNLIGHT PROTECTION; SUSTAINED DRUG RELEASE; UNSPECIFIED SIDE EFFECT; VAGINAL INJURY;

EID: 79952385770     PISSN: 00195464     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (48)

1. Bidyut KP, Satya PM. Uses and applications of microemulsions. Current Science 2001;80(8): 990-1001.
2. Jain NK. Progress in controlled and novel drug delivery st systems. 1 ed. New Delhi: CBS publishers and distributors; 2004.324.
3. Osborne D, Anton HA, Topical Drug Delivery Formulations. Informa Health Care, 1990;357
4. Hoar TP, Schulman JH. Transparent water in oil dispersions: the oleopathic hydromicelle. Nature 1943;152: 102-103.
5. Attwood D, Kreuter J. Colloidal Drug Delivery Systems. New York:Marcel Dekker;1994.31-71.
6. Derle DV, Sagar BSH, Microemulsion as a vehicle for transdermal permeation of nimesulide. Ind. J. Pharm. Sci. 2006; 68(5): 622-625.
7. Kreilgaard M,. Influence of microemulsions on cutaneous drug delivery. Bulletin Technique Gattefossé 2002;95:79-100.
8. Jain NK. Progress in controlled and novel drug delivery st systems. 1 ed. New Delhi: CBS publishers and distributors; 2004.319-320.
9. Mittal KL, Pramod P. Handbook of microemulsions science and technology. New Delhi:CRC Press; 1999. 767.
10. Jayakrishnan A, Kalaiarasi K, Shah DO. Microemulsion: Evolving technology for cosmetic applications. J. Soc.Cosmet.Chem. 1983;34:334.
11. Johnson, KA, and Shah DO. Effect of oil chain length and electrolytes on water solubilization in alcohol-free pharmaceutical microemulsions. J of Colloid and Interface Sci. 1985;107(1): 269-271.
12. Shinoda, K, Shibata Y, Lindman B. Interfacial Tensions for Lecithin Microemulsions Including the Effect of Surfactant and Polymer Addition. Langmuir 1993; 9:1254.
13. Aboofazeli R, Lawrence MJ. Investigations into the formation and characterization of phospholipid microemulsions. I. Pseudo-ternary phase diagrams of systems containing water-lecithin-alcohol-isopropyl myristate. Int. J. Pharm. 1993;93(1-3):161-175.
14. Attwood D, Mallon C, and Taylor CJ. Phase studies and particle size analysis of oil-in-water phospholipid microemulsions. Intl. J of Pharm.1995;116(2): 253-261.
15. Kumar P, Mittal KL. Handbook of microemulsion science and technology. New York:Marcel Dekker Inc;1999.457-497; 549-603:679-712; 755-77.
16. Solans C, Kunieda H,. Industrial applications of microemulsions. New York:Marcel Dekker Inc; 1997. 199, 147-174, 97-122, 123-145, 69-95.
17. Tenjarla SN. Microemulsions: An overview and pharmaceutical applications. Critical Reviews TM in Therapeutic Drug Carrier Systems.1999;16:461-521.
18. Lieberman HA, Rieger MM, Banker GS. Pharmaceutical Dosage Forms: Disperse Systems. 2nd ed. Vol 1.New York:Marcel Dekker Inc; 1996. 211-281, 315-370.
19. Puranajoti PR, Patil T, Sheth PD, Bommareddy GP, Egbaria DK. Design and Development of Topical Microemulsion for Poorly Water-Soluble Antifungal Agents The Journal of Applied Research 2002;2(1).
20. Peira E, Carlotti ME, Trotta C, Cavalli R, Trotta M. Positively charged microemulsions for topical application. Int J Pharm. 2008;346(1-2):119-23.
21. Yogeshwar B, Vandana P. Microemulsion-Based Vaginal Gel of Clotrimazole: Formulation, In vitro Evaluation, and Stability Studies. AAPS PharmSciTech. 2009;10(2):476-481.
22. Yogeshwar B, Vandana P. Microemulsion based vaginal gel of fluconazole: formulation, in vitro and in vivo evaluation Intl J Pharm. 2009;365(1-2):175-179.
23. Weiwei Zhu, Chenyu Guo, Aihua Yu, Yan Gao, Fengliang Cao and GuangXi Zhai. Microemulsion-based hydrogel formulation of penciclovir for topical delivery. International Journal of Pharmaceutics 2009;378(1-2):152-158.
24. Shishu Sunita Rajan, Kamalpreet Development of novel microemulsion based topical formulations of Acyclovir for the treatment of cutaneous herpetic infections.AAPS PharmSciTech. 2009;10(2):559-565.
25. Date AA, Naik B, Nagarsenker MS. Novel Drug Delivery Systems: Potential in Improving Topical Delivery of Antiacne Agents. Skin Pharmacology and Physiology 2006; 19:2-16.
26. Peira E. Carlotti ME, Cavalli R, Trotta M,. Journal of drug delivery science and technology: Azelaic acid sodium salt in the formulation of microemulsions for topical applications. 2006;16(5): 375-379.
27. Gallarate MR, Gasco MR, Rua G. In vitro release of azelaic acid form oil in water microemulsions. Acta Pharm Jugosla.1990;40:533.
28. Martini MC, Bobin MF, Flandin H, Caillaud F, Cotte J. Role of microemulsions in the percutaneous absorption of alpha-tocopherol. J Pharm Belg. 1984;39(6):348-54.
29. Branka R, Alenka Z, Francoise F, Mirjana G. Temperature-Sensitive Microemulsion Gel: An Effective Topical Delivery System for Simultaneous Delivery of Vitamins C and E. AAPS PharmSciTech. 2009;10(1):54-61.
30. Branka R, Mirjana G, Estelle T, Fabrice P and Francoise F. Simultaneous absorption of vitamins C and E from topical microemulsions using reconstructed human epidermis as a skin model. European J of Pharm and Biopharmaceutics 2009;72(1):69-75.
31. Rangarajan M, Zatz J. Effect of formulation on the topical delivery of alpha-tocopherol. J of Cosmet Sci. 2003;54(2):161-74.
32. Spiclin P, Homar M, Zupancic VA Gasperlin M. Sodium ascorbyl phosphate in topical microemulsions. Intl J Pharm. 2003;256(1-2):65-73.
33. Spiclin P, Gasperlin M, Kmetec V. Stability of sodium ascorbyl phosphate in topical microemulsions. Intl. J Pharm. 2001;222(2):271-9.
34. Polona Jurkovic, Marjeta Sentjurc, Mirjana Gas perlin, Julijana Kristl, Slavko Pecar. Skin protection against ultraviolet induced free radicals with ascorbyl palmitate in microemulsions Eur J Pharm Biopharm 2003;56(1):59-66.
35. Trotta M, Ugazio E, Peira E, Puritano C. Influence of ion pairing on topical delivery of retinoic acid from microemulsions. J of Controlled Release 2003;86(2-3):315-321.
36. Peira E, Carlotti ME, Cavalli R, Trotta M. Azelaic acid sodium salt in the formulation of microemulsions for topical applications. J of Drug Delivery Sci. and Tech. 2006;16(5): 375-379.
37. Subramanian N, Ghosal SK, Moulik SP. Topical delivery of celecoxib using microemulsion. Acta Pol Pharm. 2004;61(5):335-41.
38. Baroli B, López-Quintela MA, Delgado-Charro MB, Fadda AM, Blanco-Méndez Microemulsions for topical delivery of 8-methoxsalen. J of Controlled Release. 2000;3;69(1):209-218.
39. Fegn L, Wang Z. Topical chemoprevention of skin cancer in mice, using combined inhibitors of 5-lipoxygenase and cyclo-oxygenase-2. The Journal of Laryngology & Otology 2009;123(8):880-884.
40. Suppasansatorn,Panassay, Nimmannit, Ubonthip, Conway,et al,.Microemulsions as topical delivery vehicles for the anti-melanoma prodrug, temozolomide hexyl ester (TMZA-HE). J of Pharm. and Pharmacol. 2007; 59(6): 787-794.
41. Teixeira PC, Leite GM, Domingues RJ, Silva J, Gibbs PA, Ferreira JP. Detection of biofilm formation among the clinical isolates of staphylococci: An evaluation of three different screening methods. International Journal of Food Microbiology 2007;118(1):15-19.
42. Ali J, Akhtar N, Sultana Y, Baboota S, Ahuja A. Antipsoriatic microemulsion gel formulations for topical drug delivery of babchi oil (Psoralea corylifolia). Methods Find Exp Clin Pharmacol. 2008;30(4):277-85.
43. Hongzhuo L., Yongjun W., Yiyong L., Huimin Y., Yang D., Sanming Li,. Bicontinuous Cyclosporin-a loaded Water-AOT/Tween 85-isopropylmyristate microemulsion: Structural characterization and dermal pharmacokinetics in vivo. J Pharm Sci. 2009;98:1167-1176.
44. Chan J, Gamal MM, El Maghraby, Jennifer PC, Raid GA. Phase transition water-in-oil microemulsions as ocular drug delivery systems: In vitro and in vivo evaluation. Intl. J of Pharm. 2007;328(1):65-71.
45. Fialho SL, da Silva-Cunha A. New vehicle based on a microemulsion for topical ocular administration of d examethasone. ClinExperOphthalmol. 2004;32(6):626.
46. Lv FF, Li N, Zheng LQ, Tung CH. Studies on the stability of the chloramphenicol in the microemulsion free of alcohols. Eur J Pharm Biopharm. 2006;62(3):288-94.
47. D'Cruz O. Gel-microemulsions as vaginal spermicides and intravaginal drug delivery vehicles. Contraception 2001;64(2):113-123.
48. Azeem A, Rizwan M, Ahmad FJ et al. Emerging role of microemulsions in cosmetics. Recent Pat Drug Deliv Formul. 2008;2(3):275-89.