Temperature-sensitive microemulsion gel: An effective topical delivery system for simultaneous delivery of vitamins C and E

AAPS PharmSciTech

Volumn 10, Issue 1, 2009, Pages 54-61

  Rozman, Branka ^a   Zvonar, Alenka ^a   Falson, Francoise ^b   Gasperlin, Mirjana ^a  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

^b UNIVERSITÉ LYON 1   (France)

Author keywords

Antioxidant; Microemulsion gel; Rheology; Skin permeation; Vitamin

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; DRUG CARRIER; OIL; SURFACTANT; VITAMIN; WATER;

ANIMAL TISSUE; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY TEST; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG PENETRATION; DRUG RELEASE; DRUG SOLUBILITY; FLOW MEASUREMENT; HUMAN; HUMAN CELL; HYDROPHILICITY; LIPOPHILICITY; MICROEMULSION; NONHUMAN; PARTICLE SIZE; SAFETY; SKIN ABSORPTION; SKIN TEMPERATURE; SWINE; TEMPERATURE SENSITIVITY; VISCOSITY; WATER CONTENT; ANIMAL; CELL LINE; CELL SURVIVAL; CHEMISTRY; DRUG COMBINATION; DRUG EFFECT; EMULSION; FLOW KINETICS; GEL; INTRADERMAL DRUG ADMINISTRATION; KINETICS; METABOLISM; METHODOLOGY; PERMEABILITY; PHARMACEUTICS; SKIN; SOLUBILITY; TEMPERATURE;

ADMINISTRATION, CUTANEOUS; ANIMALS; ASCORBIC ACID; CELL LINE; CELL SURVIVAL; CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; DRUG COMBINATIONS; DRUG COMPOUNDING; EMULSIONS; GELS; HUMANS; KINETICS; OILS; PARTICLE SIZE; PERMEABILITY; RHEOLOGY; SKIN; SKIN ABSORPTION; SOLUBILITY; SURFACE-ACTIVE AGENTS; SWINE; TECHNOLOGY, PHARMACEUTICAL; TEMPERATURE; VISCOSITY; VITAMIN E; VITAMINS; WATER;

EID: 67549145651     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-008-9172-3     Document Type: Article

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