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Volumn 29, Issue 13, 2011, Pages 2381-2391

Immunostimulatory and antigen delivery properties of liposomes made up of total polar lipids from non-pathogenic bacteria leads to efficient induction of both innate and adaptive immune responses

Author keywords

Adjuvant; Antigen delivery vehicle; Immunostimulatory lipids; L. biflexa; Liposome; M. Smegmatis; Total polar lipids

Indexed keywords

B7 ANTIGEN; CD86 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 6; LEPTOSOME; LIPOSOME; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; SMEGMOSOME; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 79952363514     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2011.01.110     Document Type: Article
Times cited : (18)

References (77)
  • 1
    • 0026288628 scopus 로고
    • Recombinant subunit vaccines
    • Burnette W.N. Recombinant subunit vaccines. Curr Opin Biotechnol 1991, 2(6):882-892.
    • (1991) Curr Opin Biotechnol , vol.2 , Issue.6 , pp. 882-892
    • Burnette, W.N.1
  • 2
    • 55649101874 scopus 로고    scopus 로고
    • Vaccine adjuvant systems: enhancing the efficacy of sub-unit protein antigens
    • Perrie Y., Mohammed A.R., Kirby D.J., McNeil S.E., Bramwell V.W. Vaccine adjuvant systems: enhancing the efficacy of sub-unit protein antigens. Int J Pharm 2008, 364(2):272-280.
    • (2008) Int J Pharm , vol.364 , Issue.2 , pp. 272-280
    • Perrie, Y.1    Mohammed, A.R.2    Kirby, D.J.3    McNeil, S.E.4    Bramwell, V.W.5
  • 3
    • 0032490610 scopus 로고    scopus 로고
    • Aluminum compounds as vaccine adjuvants
    • Gupta R.K. Aluminum compounds as vaccine adjuvants. Adv Drug Deliv Rev 1998, 32(3):155-172.
    • (1998) Adv Drug Deliv Rev , vol.32 , Issue.3 , pp. 155-172
    • Gupta, R.K.1
  • 5
    • 35348968868 scopus 로고    scopus 로고
    • Relationship between physical and chemical properties of aluminum-containing adjuvants and immunopotentiation
    • Hem S.L., Hogenesch H. Relationship between physical and chemical properties of aluminum-containing adjuvants and immunopotentiation. Expert Rev Vaccines 2007, 6(5):685-698.
    • (2007) Expert Rev Vaccines , vol.6 , Issue.5 , pp. 685-698
    • Hem, S.L.1    Hogenesch, H.2
  • 6
    • 0032077994 scopus 로고    scopus 로고
    • Rational approaches to reduce adverse reactions in man to vaccines containing tetanus and diphtheria toxoids
    • Relyveld E.H., Bizzini B., Gupta R.K. Rational approaches to reduce adverse reactions in man to vaccines containing tetanus and diphtheria toxoids. Vaccine 1998, 16(9-10):1016-1023.
    • (1998) Vaccine , vol.16 , Issue.9-10 , pp. 1016-1023
    • Relyveld, E.H.1    Bizzini, B.2    Gupta, R.K.3
  • 7
    • 0037205089 scopus 로고    scopus 로고
    • Overview of vaccine adjuvants: present and future
    • Hunter R.L. Overview of vaccine adjuvants: present and future. Vaccine 2002, 20(Suppl. 3):S7-12.
    • (2002) Vaccine , vol.20 , Issue.SUPPL. 3
    • Hunter, R.L.1
  • 8
    • 0026473039 scopus 로고
    • Immunologic aspects of liposomes: presentation and processing of liposomal protein and phospholipid antigens
    • Alving C.R. Immunologic aspects of liposomes: presentation and processing of liposomal protein and phospholipid antigens. Biochim Biophys Acta 1992, 1113(3-4):307-322.
    • (1992) Biochim Biophys Acta , vol.1113 , Issue.3-4 , pp. 307-322
    • Alving, C.R.1
  • 9
    • 57649213862 scopus 로고    scopus 로고
    • Leptospira immunoglobulin-like protein A variable region (LigAvar) incorporated in liposomes and PLGA microspheres produces a robust immune response correlating to protective immunity
    • Faisal S.M., Yan W., McDonough S.P., Chang Y.F. Leptospira immunoglobulin-like protein A variable region (LigAvar) incorporated in liposomes and PLGA microspheres produces a robust immune response correlating to protective immunity. Vaccine 2009, 27(3):378-387.
    • (2009) Vaccine , vol.27 , Issue.3 , pp. 378-387
    • Faisal, S.M.1    Yan, W.2    McDonough, S.P.3    Chang, Y.F.4
  • 11
    • 0028559138 scopus 로고
    • The immunological adjuvant and vaccine carrier properties of liposomes
    • Gregoriadis G. The immunological adjuvant and vaccine carrier properties of liposomes. J Drug Target 1994, 2(5):351-356.
    • (1994) J Drug Target , vol.2 , Issue.5 , pp. 351-356
    • Gregoriadis, G.1
  • 13
    • 33749444615 scopus 로고    scopus 로고
    • Pre-clinical evaluation of new adjuvant formulations to improve the immunogenicity of the malaria vaccine RTS,S/AS02A
    • Stewart V.A., McGrath S.M., Walsh D.S., Davis S., Hess A.S., Ware L.A., et al. Pre-clinical evaluation of new adjuvant formulations to improve the immunogenicity of the malaria vaccine RTS,S/AS02A. Vaccine 2006, 24(42-43):6483-6492.
    • (2006) Vaccine , vol.24 , Issue.42-43 , pp. 6483-6492
    • Stewart, V.A.1    McGrath, S.M.2    Walsh, D.S.3    Davis, S.4    Hess, A.S.5    Ware, L.A.6
  • 14
    • 0019205038 scopus 로고
    • Humoral and cellular immunity to hepatitis B virus-derived antigens: comparative activity of Freund complete adjuvant alum, and liposomes
    • Sanchez Y., Ionescu-Matiu I., Dreesman G.R., Kramp W., Six H.R., Hollinger F.B., et al. Humoral and cellular immunity to hepatitis B virus-derived antigens: comparative activity of Freund complete adjuvant alum, and liposomes. Infect Immun 1980, 30(3):728-733.
    • (1980) Infect Immun , vol.30 , Issue.3 , pp. 728-733
    • Sanchez, Y.1    Ionescu-Matiu, I.2    Dreesman, G.R.3    Kramp, W.4    Six, H.R.5    Hollinger, F.B.6
  • 15
    • 0030819524 scopus 로고    scopus 로고
    • Immunogenicity and protectivity of a new liposomal hepatitis A vaccine
    • Ambrosch F., Wiedermann G., Jonas S., Althaus B., Finkel B., Gluck R., et al. Immunogenicity and protectivity of a new liposomal hepatitis A vaccine. Vaccine 1997, 15(11):1209-1213.
    • (1997) Vaccine , vol.15 , Issue.11 , pp. 1209-1213
    • Ambrosch, F.1    Wiedermann, G.2    Jonas, S.3    Althaus, B.4    Finkel, B.5    Gluck, R.6
  • 16
    • 39249083535 scopus 로고    scopus 로고
    • Vaccine adjuvant systems containing monophosphoryl lipid A and QS21 induce strong and persistent humoral and T cell responses against hepatitis B surface antigen in healthy adult volunteers
    • Vandepapeliere P., Horsmans Y., Moris P., Van Mechelen M., Janssens M., Koutsoukos M., et al. Vaccine adjuvant systems containing monophosphoryl lipid A and QS21 induce strong and persistent humoral and T cell responses against hepatitis B surface antigen in healthy adult volunteers. Vaccine 2008, 26(10):1375-1386.
    • (2008) Vaccine , vol.26 , Issue.10 , pp. 1375-1386
    • Vandepapeliere, P.1    Horsmans, Y.2    Moris, P.3    Van Mechelen, M.4    Janssens, M.5    Koutsoukos, M.6
  • 17
    • 0031669047 scopus 로고    scopus 로고
    • Effectiveness of liposomes possessing surface-linked recombinant B subunit of cholera toxin as an oral antigen delivery system
    • Harokopakis E., Hajishengallis G., Michalek S.M. Effectiveness of liposomes possessing surface-linked recombinant B subunit of cholera toxin as an oral antigen delivery system. Infect Immun 1998, 66(9):4299-4304.
    • (1998) Infect Immun , vol.66 , Issue.9 , pp. 4299-4304
    • Harokopakis, E.1    Hajishengallis, G.2    Michalek, S.M.3
  • 18
    • 0030468106 scopus 로고    scopus 로고
    • Cytokine-containing liposomes as vaccine adjuvants
    • Lachman L.B., Ozpolat B., Rao X.M. Cytokine-containing liposomes as vaccine adjuvants. Eur Cytokine Netw 1996, 7(4):693-698.
    • (1996) Eur Cytokine Netw , vol.7 , Issue.4 , pp. 693-698
    • Lachman, L.B.1    Ozpolat, B.2    Rao, X.M.3
  • 19
    • 0031841564 scopus 로고    scopus 로고
    • Liposomes containing lipid A serve as an adjuvant for induction of antibody and cytotoxic T-cell responses against RTS,S malaria antigen
    • Richards R.L., Rao M., Wassef N.M., Glenn G.M., Rothwell S.W., Alving C.R. Liposomes containing lipid A serve as an adjuvant for induction of antibody and cytotoxic T-cell responses against RTS,S malaria antigen. Infect Immun 1998, 66(6):2859-2865.
    • (1998) Infect Immun , vol.66 , Issue.6 , pp. 2859-2865
    • Richards, R.L.1    Rao, M.2    Wassef, N.M.3    Glenn, G.M.4    Rothwell, S.W.5    Alving, C.R.6
  • 21
    • 0030666222 scopus 로고    scopus 로고
    • Innate immunity: the virtues of a nonclonal system of recognition
    • Medzhitov R., Janeway C.A. Innate immunity: the virtues of a nonclonal system of recognition. Cell 1997, 91(3):295-298.
    • (1997) Cell , vol.91 , Issue.3 , pp. 295-298
    • Medzhitov, R.1    Janeway, C.A.2
  • 22
    • 0023821578 scopus 로고
    • Introduction of soluble protein into the class I pathway of antigen processing and presentation
    • Moore M.W., Carbone F.R., Bevan M.J. Introduction of soluble protein into the class I pathway of antigen processing and presentation. Cell 1988, 54(6):777-785.
    • (1988) Cell , vol.54 , Issue.6 , pp. 777-785
    • Moore, M.W.1    Carbone, F.R.2    Bevan, M.J.3
  • 23
    • 0026556490 scopus 로고
    • Enhanced antibody response to liposome-associated protein antigens: preferential stimulation of IgG2a/b production
    • Phillips N.C., Emili A. Enhanced antibody response to liposome-associated protein antigens: preferential stimulation of IgG2a/b production. Vaccine 1992, 10(3):151-158.
    • (1992) Vaccine , vol.10 , Issue.3 , pp. 151-158
    • Phillips, N.C.1    Emili, A.2
  • 24
    • 0025835150 scopus 로고
    • Liposome adjuvanticity: influence of dose and protein:lipid ratio on the humoral response to encapsulated and surface-linked antigen
    • Therien H.M., Shahum E., Fortin A. Liposome adjuvanticity: influence of dose and protein:lipid ratio on the humoral response to encapsulated and surface-linked antigen. Cell Immunol 1991, 136(2):402-413.
    • (1991) Cell Immunol , vol.136 , Issue.2 , pp. 402-413
    • Therien, H.M.1    Shahum, E.2    Fortin, A.3
  • 25
    • 36049033394 scopus 로고    scopus 로고
    • Signaling to NF-kappaB by Toll-like receptors
    • Kawai T., Akira S. Signaling to NF-kappaB by Toll-like receptors. Trends Mol Med 2007, 13(11):460-469.
    • (2007) Trends Mol Med , vol.13 , Issue.11 , pp. 460-469
    • Kawai, T.1    Akira, S.2
  • 26
    • 17644416719 scopus 로고    scopus 로고
    • Targeting the innate immune response with improved vaccine adjuvants
    • Pashine A., Valiante N.M., Ulmer J.B. Targeting the innate immune response with improved vaccine adjuvants. Nat Med 2005, 11(4 Suppl.):S63-S68.
    • (2005) Nat Med , vol.11 , Issue.4 SUPPL.
    • Pashine, A.1    Valiante, N.M.2    Ulmer, J.B.3
  • 27
    • 0037407849 scopus 로고    scopus 로고
    • Role of innate immune factors in the adjuvant activity of monophosphoryl lipid A
    • Martin M., Michalek S.M., Katz J. Role of innate immune factors in the adjuvant activity of monophosphoryl lipid A. Infect Immun 2003, 71(5):2498-2507.
    • (2003) Infect Immun , vol.71 , Issue.5 , pp. 2498-2507
    • Martin, M.1    Michalek, S.M.2    Katz, J.3
  • 28
    • 0031986108 scopus 로고    scopus 로고
    • Adjuvant activity of muramyl dipeptide derivatives to enhance immunogenicity of a hantavirus-inactivated vaccine
    • Yoo Y.C., Yoshimatsu K., Koike Y., Hatsuse R., Yamanishi K., Tanishita O., et al. Adjuvant activity of muramyl dipeptide derivatives to enhance immunogenicity of a hantavirus-inactivated vaccine. Vaccine 1998, 16(2-3):216-224.
    • (1998) Vaccine , vol.16 , Issue.2-3 , pp. 216-224
    • Yoo, Y.C.1    Yoshimatsu, K.2    Koike, Y.3    Hatsuse, R.4    Yamanishi, K.5    Tanishita, O.6
  • 29
    • 28144437548 scopus 로고    scopus 로고
    • Characterization of cationic liposomes based on dimethyldioctadecylammonium and synthetic cord factor from M. tuberculosis (trehalose 6,6'-dibehenate) - a novel adjuvant inducing both strong CMI and antibody responses
    • Davidsen J., Rosenkrands I., Christensen D., Vangala A., Kirby D., Perrie Y., et al. Characterization of cationic liposomes based on dimethyldioctadecylammonium and synthetic cord factor from M. tuberculosis (trehalose 6,6'-dibehenate) - a novel adjuvant inducing both strong CMI and antibody responses. Biochim Biophys Acta 2005, 1718(1-2):22-31.
    • (2005) Biochim Biophys Acta , vol.1718 , Issue.1-2 , pp. 22-31
    • Davidsen, J.1    Rosenkrands, I.2    Christensen, D.3    Vangala, A.4    Kirby, D.5    Perrie, Y.6
  • 30
    • 0035993210 scopus 로고    scopus 로고
    • Lipopeptide adjuvants: monitoring and comparison of P3CSK4- and LPS-induced gene transcription
    • Muller M.R., Wiesmuller K.H., Jung G., Loop T., Humar M., Pfannes S.D., et al. Lipopeptide adjuvants: monitoring and comparison of P3CSK4- and LPS-induced gene transcription. Int Immunopharmacol 2002, 2(8):1065-1077.
    • (2002) Int Immunopharmacol , vol.2 , Issue.8 , pp. 1065-1077
    • Muller, M.R.1    Wiesmuller, K.H.2    Jung, G.3    Loop, T.4    Humar, M.5    Pfannes, S.D.6
  • 31
    • 33751039274 scopus 로고    scopus 로고
    • Role of fusogenic non-PC liposomes in elicitation of protective immune response against experimental murine salmonellosis
    • Ahmad N., Deeba F., Faisal S.M., Khan A., Agrewala J.N., Dwivedi V., et al. Role of fusogenic non-PC liposomes in elicitation of protective immune response against experimental murine salmonellosis. Biochimie 2006, 88(10):1391-1400.
    • (2006) Biochimie , vol.88 , Issue.10 , pp. 1391-1400
    • Ahmad, N.1    Deeba, F.2    Faisal, S.M.3    Khan, A.4    Agrewala, J.N.5    Dwivedi, V.6
  • 32
    • 1342344918 scopus 로고    scopus 로고
    • Combination of the cationic surfactant dimethyl dioctadecyl ammonium bromide and synthetic mycobacterial cord factor as an efficient adjuvant for tuberculosis subunit vaccines
    • Holten-Andersen L., Doherty T.M., Korsholm K.S., Andersen P. Combination of the cationic surfactant dimethyl dioctadecyl ammonium bromide and synthetic mycobacterial cord factor as an efficient adjuvant for tuberculosis subunit vaccines. Infect Immun 2004, 72(3):1608-1617.
    • (2004) Infect Immun , vol.72 , Issue.3 , pp. 1608-1617
    • Holten-Andersen, L.1    Doherty, T.M.2    Korsholm, K.S.3    Andersen, P.4
  • 33
    • 0033957435 scopus 로고    scopus 로고
    • Archaeosome vaccine adjuvants induce strong humoral, cell-mediated, and memory responses: comparison to conventional liposomes and alum
    • Krishnan L., Dicaire C.J., Patel G.B., Sprott G.D. Archaeosome vaccine adjuvants induce strong humoral, cell-mediated, and memory responses: comparison to conventional liposomes and alum. Infect Immun 2000, 68(1):54-63.
    • (2000) Infect Immun , vol.68 , Issue.1 , pp. 54-63
    • Krishnan, L.1    Dicaire, C.J.2    Patel, G.B.3    Sprott, G.D.4
  • 34
    • 23944460116 scopus 로고    scopus 로고
    • Cationic liposomes containing mycobacterial lipids: a new powerful Th1 adjuvant system
    • Rosenkrands I., Agger E.M., Olsen A.W., Korsholm K.S., Andersen C.S., Jensen K.T., et al. Cationic liposomes containing mycobacterial lipids: a new powerful Th1 adjuvant system. Infect Immun 2005, 73(9):5817-5826.
    • (2005) Infect Immun , vol.73 , Issue.9 , pp. 5817-5826
    • Rosenkrands, I.1    Agger, E.M.2    Olsen, A.W.3    Korsholm, K.S.4    Andersen, C.S.5    Jensen, K.T.6
  • 35
    • 32544433906 scopus 로고    scopus 로고
    • Non PC liposome entrapped promastigote antigens elicit parasite specific CD8+ and CD4+ T-cell immune response and protect hamsters against visceral leishmaniasis
    • Sharma S.K., Dube A., Nadeem A., Khan S., Saleem I., Garg R., et al. Non PC liposome entrapped promastigote antigens elicit parasite specific CD8+ and CD4+ T-cell immune response and protect hamsters against visceral leishmaniasis. Vaccine 2006, 24(11):1800-1810.
    • (2006) Vaccine , vol.24 , Issue.11 , pp. 1800-1810
    • Sharma, S.K.1    Dube, A.2    Nadeem, A.3    Khan, S.4    Saleem, I.5    Garg, R.6
  • 36
    • 70350566092 scopus 로고    scopus 로고
    • Leptosome-entrapped leptospiral antigens conferred significant higher levels of protection than those entrapped with PC-liposomes in a hamster model
    • Faisal S.M., Yan W., McDonough S.P., Chang C.F., Pan M.J., Chang Y.F. Leptosome-entrapped leptospiral antigens conferred significant higher levels of protection than those entrapped with PC-liposomes in a hamster model. Vaccine 2009, 27(47):6537-6545.
    • (2009) Vaccine , vol.27 , Issue.47 , pp. 6537-6545
    • Faisal, S.M.1    Yan, W.2    McDonough, S.P.3    Chang, C.F.4    Pan, M.J.5    Chang, Y.F.6
  • 37
    • 0038740885 scopus 로고    scopus 로고
    • Antigen entrapped in the escheriosomes leads to the generation of CD4(+) helper and CD8(+) cytotoxic T cell response
    • Syed F.M., Khan M.A., Nasti T.H., Ahmad N., Mohammad O. Antigen entrapped in the escheriosomes leads to the generation of CD4(+) helper and CD8(+) cytotoxic T cell response. Vaccine 2003, 21(19-20):2383-2393.
    • (2003) Vaccine , vol.21 , Issue.19-20 , pp. 2383-2393
    • Syed, F.M.1    Khan, M.A.2    Nasti, T.H.3    Ahmad, N.4    Mohammad, O.5
  • 38
    • 70349785161 scopus 로고    scopus 로고
    • Immune response and prophylactic efficacy of smegmosomes in a hamster model of leptospirosis
    • Faisal S.M., Yan W., McDonough S.P., Mohammed H.O., Divers T.J., Chang Y.F. Immune response and prophylactic efficacy of smegmosomes in a hamster model of leptospirosis. Vaccine 2009, 27(44):6129-6136.
    • (2009) Vaccine , vol.27 , Issue.44 , pp. 6129-6136
    • Faisal, S.M.1    Yan, W.2    McDonough, S.P.3    Mohammed, H.O.4    Divers, T.J.5    Chang, Y.F.6
  • 39
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh E.G., Dyer W.J. A rapid method of total lipid extraction and purification. Can J Biochem Physiol 1959, 37(8):911-917.
    • (1959) Can J Biochem Physiol , vol.37 , Issue.8 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 40
    • 0027941828 scopus 로고
    • Entrapment of haemoglobin into liposomes by the dehydration-rehydration method: vesicle characterization and in vivo behaviour
    • Brandl M., Gregoriadis G. Entrapment of haemoglobin into liposomes by the dehydration-rehydration method: vesicle characterization and in vivo behaviour. Biochim Biophys Acta 1994, 1196(1):65-75.
    • (1994) Biochim Biophys Acta , vol.1196 , Issue.1 , pp. 65-75
    • Brandl, M.1    Gregoriadis, G.2
  • 41
    • 0026481133 scopus 로고
    • Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor
    • Inaba K., Inaba M., Romani N., Aya H., Deguchi M., Ikehara S., et al. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J Exp Med 1992, 176(6):1693-1702.
    • (1992) J Exp Med , vol.176 , Issue.6 , pp. 1693-1702
    • Inaba, K.1    Inaba, M.2    Romani, N.3    Aya, H.4    Deguchi, M.5    Ikehara, S.6
  • 42
    • 0035170635 scopus 로고    scopus 로고
    • Fusogenic potential of prokaryotic membrane lipids. Implication in vaccine development
    • Ahmad N., Masood A.K., Owais M. Fusogenic potential of prokaryotic membrane lipids. Implication in vaccine development. Eur J Biochem 2001, 268(22):5667-5675.
    • (2001) Eur J Biochem , vol.268 , Issue.22 , pp. 5667-5675
    • Ahmad, N.1    Masood, A.K.2    Owais, M.3
  • 43
    • 0028087602 scopus 로고
    • A tetrazolium-based colorimetric MTT assay to quantitate human monocyte mediated cytotoxicity against leukemic cells from cell lines and patients with acute myeloid leukemia
    • van de Loosdrecht A.A., Beelen R.H., Ossenkoppele G.J., Broekhoven M.G., Langenhuijsen M.M. A tetrazolium-based colorimetric MTT assay to quantitate human monocyte mediated cytotoxicity against leukemic cells from cell lines and patients with acute myeloid leukemia. J Immunol Methods 1994, 174(1-2):311-320.
    • (1994) J Immunol Methods , vol.174 , Issue.1-2 , pp. 311-320
    • van de Loosdrecht, A.A.1    Beelen, R.H.2    Ossenkoppele, G.J.3    Broekhoven, M.G.4    Langenhuijsen, M.M.5
  • 45
    • 37249015372 scopus 로고    scopus 로고
    • Evaluation of protective immunity of Leptospira immunoglobulin like protein A (LigA) DNA vaccine against challenge in hamsters
    • Faisal S.M., Yan W., Chen C.S., Palaniappan R.U., McDonough S.P., Chang Y.F. Evaluation of protective immunity of Leptospira immunoglobulin like protein A (LigA) DNA vaccine against challenge in hamsters. Vaccine 2008, 26(2):277-287.
    • (2008) Vaccine , vol.26 , Issue.2 , pp. 277-287
    • Faisal, S.M.1    Yan, W.2    Chen, C.S.3    Palaniappan, R.U.4    McDonough, S.P.5    Chang, Y.F.6
  • 46
    • 0021038289 scopus 로고
    • An enzyme-release assay for natural cytotoxicity
    • Korzeniewski C., Callewaert D.M. An enzyme-release assay for natural cytotoxicity. J Immunol Methods 1983, 64(3):313-320.
    • (1983) J Immunol Methods , vol.64 , Issue.3 , pp. 313-320
    • Korzeniewski, C.1    Callewaert, D.M.2
  • 47
    • 0021020342 scopus 로고
    • A solid-phase enzyme-linked immunospot (ELISPOT) assay for enumeration of specific antibody-secreting cells
    • Czerkinsky C.C., Nilsson L.A., Nygren H., Ouchterlony O., Tarkowski A. A solid-phase enzyme-linked immunospot (ELISPOT) assay for enumeration of specific antibody-secreting cells. J Immunol Methods 1983, 65(1-2):109-121.
    • (1983) J Immunol Methods , vol.65 , Issue.1-2 , pp. 109-121
    • Czerkinsky, C.C.1    Nilsson, L.A.2    Nygren, H.3    Ouchterlony, O.4    Tarkowski, A.5
  • 49
    • 61449266273 scopus 로고    scopus 로고
    • Immunogenicity and protective efficacy of recombinant Leptospira immunoglobulin-like protein B (rLigB) in a hamster challenge model
    • Yan W., Faisal S.M., McDonough S.P., Divers T.J., Barr S.C., Chang C.F., et al. Immunogenicity and protective efficacy of recombinant Leptospira immunoglobulin-like protein B (rLigB) in a hamster challenge model. Microbes Infect 2009, 11(2):230-237.
    • (2009) Microbes Infect , vol.11 , Issue.2 , pp. 230-237
    • Yan, W.1    Faisal, S.M.2    McDonough, S.P.3    Divers, T.J.4    Barr, S.C.5    Chang, C.F.6
  • 50
    • 77049248972 scopus 로고
    • The mode of action of immunologic adjuvants
    • Freund J. The mode of action of immunologic adjuvants. Bibl Tuberc 1956, 10(10):130-148.
    • (1956) Bibl Tuberc , vol.10 , Issue.10 , pp. 130-148
    • Freund, J.1
  • 51
    • 0032387991 scopus 로고    scopus 로고
    • Enhancing activity of mycobacterial cell-derived adjuvants on immunogenicity of recombinant human hepatitis B virus vaccine
    • Koike Y., Yoo Y.C., Mitobe M., Oka T., Okuma K., Tono-oka S., et al. Enhancing activity of mycobacterial cell-derived adjuvants on immunogenicity of recombinant human hepatitis B virus vaccine. Vaccine 1998, 16(20):1982-1989.
    • (1998) Vaccine , vol.16 , Issue.20 , pp. 1982-1989
    • Koike, Y.1    Yoo, Y.C.2    Mitobe, M.3    Oka, T.4    Okuma, K.5    Tono-oka, S.6
  • 52
    • 2342625401 scopus 로고    scopus 로고
    • Interaction of dendritic cells with antigen-containing liposomes: effect of bilayer composition
    • Foged C., Arigita C., Sundblad A., Jiskoot W., Storm G., Frokjaer S. Interaction of dendritic cells with antigen-containing liposomes: effect of bilayer composition. Vaccine 2004, 22(15-16):1903-1913.
    • (2004) Vaccine , vol.22 , Issue.15-16 , pp. 1903-1913
    • Foged, C.1    Arigita, C.2    Sundblad, A.3    Jiskoot, W.4    Storm, G.5    Frokjaer, S.6
  • 53
    • 0035253359 scopus 로고    scopus 로고
    • The potent adjuvant activity of archaeosomes correlates to the recruitment and activation of macrophages and dendritic cells in vivo
    • Krishnan L., Sad S., Patel G.B., Sprott G.D. The potent adjuvant activity of archaeosomes correlates to the recruitment and activation of macrophages and dendritic cells in vivo. J Immunol 2001, 166(3):1885-1893.
    • (2001) J Immunol , vol.166 , Issue.3 , pp. 1885-1893
    • Krishnan, L.1    Sad, S.2    Patel, G.B.3    Sprott, G.D.4
  • 54
    • 0030174295 scopus 로고    scopus 로고
    • Influence of phospholipid composition on antibody responses to liposome encapsulated protein and peptide antigens
    • Phillips N.C., Gagne L., Ivanoff N., Riveau G. Influence of phospholipid composition on antibody responses to liposome encapsulated protein and peptide antigens. Vaccine 1996, 14(9):898-904.
    • (1996) Vaccine , vol.14 , Issue.9 , pp. 898-904
    • Phillips, N.C.1    Gagne, L.2    Ivanoff, N.3    Riveau, G.4
  • 55
    • 4544288852 scopus 로고    scopus 로고
    • Activation of dendritic cells by liposomes prepared from phosphatidylinositol mannosides from Mycobacterium bovis bacillus Calmette-Guerin and adjuvant activity in vivo
    • Sprott G.D., Dicaire C.J., Gurnani K., Sad S., Krishnan L. Activation of dendritic cells by liposomes prepared from phosphatidylinositol mannosides from Mycobacterium bovis bacillus Calmette-Guerin and adjuvant activity in vivo. Infect Immun 2004, 72(9):5235-5246.
    • (2004) Infect Immun , vol.72 , Issue.9 , pp. 5235-5246
    • Sprott, G.D.1    Dicaire, C.J.2    Gurnani, K.3    Sad, S.4    Krishnan, L.5
  • 56
    • 0035845725 scopus 로고    scopus 로고
    • Evaluation of particle uptake in human blood monocyte-derived cells in vitro. Does phagocytosis activity of dendritic cells measure up with macrophages?
    • Thiele L., Rothen-Rutishauser B., Jilek S., Wunderli-Allenspach H., Merkle H.P., Walter E. Evaluation of particle uptake in human blood monocyte-derived cells in vitro. Does phagocytosis activity of dendritic cells measure up with macrophages?. J Control Release 2001, 76(1-2):59-71.
    • (2001) J Control Release , vol.76 , Issue.1-2 , pp. 59-71
    • Thiele, L.1    Rothen-Rutishauser, B.2    Jilek, S.3    Wunderli-Allenspach, H.4    Merkle, H.P.5    Walter, E.6
  • 57
    • 0034037160 scopus 로고    scopus 로고
    • Fusogenic liposomes efficiently deliver exogenous antigen through the cytoplasm into the MHC class I processing pathway
    • Nakanishi T., Hayashi A., Kunisawa J., Tsutsumi Y., Tanaka K., Yashiro-Ohtani Y., et al. Fusogenic liposomes efficiently deliver exogenous antigen through the cytoplasm into the MHC class I processing pathway. Eur J Immunol 2000, 30(6):1740-1747.
    • (2000) Eur J Immunol , vol.30 , Issue.6 , pp. 1740-1747
    • Nakanishi, T.1    Hayashi, A.2    Kunisawa, J.3    Tsutsumi, Y.4    Tanaka, K.5    Yashiro-Ohtani, Y.6
  • 58
    • 0023037506 scopus 로고
    • Preparation and characterisation of liposomes containing mannosylated phospholipids capable of targetting drugs to macrophages
    • Barratt G., Tenu J.P., Yapo A., Petit J.F. Preparation and characterisation of liposomes containing mannosylated phospholipids capable of targetting drugs to macrophages. Biochim Biophys Acta 1986, 862(1):153-164.
    • (1986) Biochim Biophys Acta , vol.862 , Issue.1 , pp. 153-164
    • Barratt, G.1    Tenu, J.P.2    Yapo, A.3    Petit, J.F.4
  • 59
    • 0035399862 scopus 로고    scopus 로고
    • Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite
    • Campos M.A., Almeida I.C., Takeuchi O., Akira S., Valente E.P., Procopio D.O., et al. Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite. J Immunol 2001, 167(1):416-423.
    • (2001) J Immunol , vol.167 , Issue.1 , pp. 416-423
    • Campos, M.A.1    Almeida, I.C.2    Takeuchi, O.3    Akira, S.4    Valente, E.P.5    Procopio, D.O.6
  • 60
    • 0027421831 scopus 로고
    • Interleukin-6 in biology and medicine
    • Akira S., Taga T., Kishimoto T. Interleukin-6 in biology and medicine. Adv Immunol 1993, 54:1-78.
    • (1993) Adv Immunol , vol.54 , pp. 1-78
    • Akira, S.1    Taga, T.2    Kishimoto, T.3
  • 61
    • 0029557309 scopus 로고
    • Interleukin-12: a proinflammatory cytokine with immunoregulatory functions
    • Trinchieri G., Scott P. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions. Res Immunol 1995, 146(7-8):423-431.
    • (1995) Res Immunol , vol.146 , Issue.7-8 , pp. 423-431
    • Trinchieri, G.1    Scott, P.2
  • 62
    • 0028949152 scopus 로고
    • B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy
    • Kuchroo V.K., Das M.P., Brown J.A., Ranger A.M., Zamvil S.S., Sobel R.A., et al. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy. Cell 1995, 80(5):707-718.
    • (1995) Cell , vol.80 , Issue.5 , pp. 707-718
    • Kuchroo, V.K.1    Das, M.P.2    Brown, J.A.3    Ranger, A.M.4    Zamvil, S.S.5    Sobel, R.A.6
  • 63
    • 0028819315 scopus 로고
    • CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL
    • Lanier L.L., O'Fallon S., Somoza C., Phillips J.H., Linsley P.S., Okumura K., et al. CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL. J Immunol 1995, 154(1):97-105.
    • (1995) J Immunol , vol.154 , Issue.1 , pp. 97-105
    • Lanier, L.L.1    O'Fallon, S.2    Somoza, C.3    Phillips, J.H.4    Linsley, P.S.5    Okumura, K.6
  • 64
    • 0027222833 scopus 로고
    • Adjuvants: Current status, clinical perspectives and future prospects
    • Audibert F.M., Lise L.D., Adjuvants: current status, clinical perspectives and future prospects. Immunol Today 1993, 14(6):281-284.
    • (1993) Immunol Today , vol.14 , Issue.6 , pp. 281-284
    • Audibert, F.M.1    Lise, L.D.2
  • 65
    • 0033618562 scopus 로고    scopus 로고
    • Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors
    • Brightbill H.D., Libraty D.H., Krutzik S.R., Yang R.B., Belisle J.T., Bleharski J.R., et al. Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. Science 1999, 285(5428):732-736.
    • (1999) Science , vol.285 , Issue.5428 , pp. 732-736
    • Brightbill, H.D.1    Libraty, D.H.2    Krutzik, S.R.3    Yang, R.B.4    Belisle, J.T.5    Bleharski, J.R.6
  • 66
    • 0029935132 scopus 로고    scopus 로고
    • Neisserial porins induce B lymphocytes to express costimulatory B7-2 molecules and to proliferate
    • Wetzler L.M., Ho Y., Reiser H. Neisserial porins induce B lymphocytes to express costimulatory B7-2 molecules and to proliferate. J Exp Med 1996, 183(3):1151-1159.
    • (1996) J Exp Med , vol.183 , Issue.3 , pp. 1151-1159
    • Wetzler, L.M.1    Ho, Y.2    Reiser, H.3
  • 67
    • 0030918819 scopus 로고    scopus 로고
    • T cell stimulation in vivo by lipopolysaccharide (LPS)
    • Tough D.F., Sun S., Sprent J. T cell stimulation in vivo by lipopolysaccharide (LPS). J Exp Med 1997, 185(12):2089-2094.
    • (1997) J Exp Med , vol.185 , Issue.12 , pp. 2089-2094
    • Tough, D.F.1    Sun, S.2    Sprent, J.3
  • 68
    • 0020527183 scopus 로고
    • Endotoxin-induced T lymphocyte proliferation
    • Vogel S.N., Hilfiker M.L., Caulfield M.J. Endotoxin-induced T lymphocyte proliferation. J Immunol 1983, 130(4):1774-1779.
    • (1983) J Immunol , vol.130 , Issue.4 , pp. 1774-1779
    • Vogel, S.N.1    Hilfiker, M.L.2    Caulfield, M.J.3
  • 69
    • 0033564665 scopus 로고    scopus 로고
    • Direct effects on antigen-presenting cells and T lymphocytes explain the adjuvanticity of a nontoxic cholera toxin mutant
    • Yamamoto M., Kiyono H., Yamamoto S., Batanero E., Kweon M.N., Otake S., et al. Direct effects on antigen-presenting cells and T lymphocytes explain the adjuvanticity of a nontoxic cholera toxin mutant. J Immunol 1999, 162(12):7015-7021.
    • (1999) J Immunol , vol.162 , Issue.12 , pp. 7015-7021
    • Yamamoto, M.1    Kiyono, H.2    Yamamoto, S.3    Batanero, E.4    Kweon, M.N.5    Otake, S.6
  • 70
    • 0029987839 scopus 로고    scopus 로고
    • The instructive role of innate immunity in the acquired immune response
    • Fearon D.T., Locksley R.M. The instructive role of innate immunity in the acquired immune response. Science 1996, 272(5258):50-53.
    • (1996) Science , vol.272 , Issue.5258 , pp. 50-53
    • Fearon, D.T.1    Locksley, R.M.2
  • 71
    • 0023936750 scopus 로고
    • IFN-gamma stimulates IgG2a secretion by murine B cells stimulated with bacterial lipopolysaccharide
    • Snapper C.M., Peschel C., Paul W.E. IFN-gamma stimulates IgG2a secretion by murine B cells stimulated with bacterial lipopolysaccharide. J Immunol 1988, 140(7):2121-2127.
    • (1988) J Immunol , vol.140 , Issue.7 , pp. 2121-2127
    • Snapper, C.M.1    Peschel, C.2    Paul, W.E.3
  • 72
    • 0023197097 scopus 로고
    • Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production
    • Snapper C.M., Paul W.E. Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production. Science 1987, 236(4804):944-947.
    • (1987) Science , vol.236 , Issue.4804 , pp. 944-947
    • Snapper, C.M.1    Paul, W.E.2
  • 74
    • 53649103502 scopus 로고    scopus 로고
    • Sperm membrane lipid liposomes can evoke an effective immune response against encapsulated antigen in BALB/c mice
    • Atif S.M., Salam N., Ahmad N., Hasan I.M., Jamal H.S., Sudhanshu A., et al. Sperm membrane lipid liposomes can evoke an effective immune response against encapsulated antigen in BALB/c mice. Vaccine 2008, 26(46):5874-5882.
    • (2008) Vaccine , vol.26 , Issue.46 , pp. 5874-5882
    • Atif, S.M.1    Salam, N.2    Ahmad, N.3    Hasan, I.M.4    Jamal, H.S.5    Sudhanshu, A.6
  • 75
    • 0033931743 scopus 로고    scopus 로고
    • Liposome-mediated cytosolic delivery of macromolecules and its possible use in vaccine development
    • Owais M., Gupta C.M. Liposome-mediated cytosolic delivery of macromolecules and its possible use in vaccine development. Eur J Biochem 2000, 267(13):3946-3956.
    • (2000) Eur J Biochem , vol.267 , Issue.13 , pp. 3946-3956
    • Owais, M.1    Gupta, C.M.2
  • 76
    • 59849124393 scopus 로고    scopus 로고
    • A simple mycobacterial monomycolated glycerol lipid has potent immunostimulatory activity
    • Andersen C.S., Agger E.M., Rosenkrands I., Gomes J.M., Bhowruth V., Gibson K.J., et al. A simple mycobacterial monomycolated glycerol lipid has potent immunostimulatory activity. J Immunol 2009, 182(1):424-432.
    • (2009) J Immunol , vol.182 , Issue.1 , pp. 424-432
    • Andersen, C.S.1    Agger, E.M.2    Rosenkrands, I.3    Gomes, J.M.4    Bhowruth, V.5    Gibson, K.J.6
  • 77
    • 68149181484 scopus 로고    scopus 로고
    • Proinflammatory adjuvants enhance the cognate helper activity of aged CD4 T cells
    • Maue A.C., Eaton S.M., Lanthier P.A., Sweet K.B., Blumerman S.L., Haynes L. Proinflammatory adjuvants enhance the cognate helper activity of aged CD4 T cells. J Immunol 2009, 182(10):6129-6135.
    • (2009) J Immunol , vol.182 , Issue.10 , pp. 6129-6135
    • Maue, A.C.1    Eaton, S.M.2    Lanthier, P.A.3    Sweet, K.B.4    Blumerman, S.L.5    Haynes, L.6


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