Leptosome-entrapped leptospiral antigens conferred significant higher levels of protection than those entrapped with PC-liposomes in a hamster model

Vaccine

Volumn 27, Issue 47, 2009, Pages 6537-6545

  Faisal, Syed M ^a   Yan, WeiWei ^a   McDonough, Sean P ^a   Chang, Chao Fu ^b   Pan, Ming Jeng ^b   Chang, Yung Fu ^a  

^a Department of Obstetrics Gynecology   (United States)

^b CENTRAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

Adjuvant; Leptospira; Leptospira interrogans; Lipid; Liposome

Indexed keywords

BACTERIAL ANTIGEN; CYTOKINE; ESCHERIOSOME; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 4; LEPTOSOME; LIPID; LIPOSOME; LP0607 ANTIGEN; LP118 ANTIGEN; LP1454 ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; BACTERIAL VIRULENCE; CELL ISOLATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; ESCHERICHIA COLI; EVALUATION; FEMALE; HAMSTER; HISTOPATHOLOGY; IMMUNIZATION; KIDNEY; LD 50; LEPTOSPIRA; LEPTOSPIRA BIFLEXA; LYMPHOCYTE PROLIFERATION; LYMPHOCYTIC INFILTRATION; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; SURVIVAL; TH1 CELL;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENS, BACTERIAL; CELL PROLIFERATION; CRICETINAE; CYTOKINES; FEMALE; IMMUNITY, HUMORAL; IMMUNOLOGIC MEMORY; KIDNEY; LEPTOSPIRA INTERROGANS SEROVAR POMONA; LEPTOSPIROSIS; LIPOSOMES; LYMPHOCYTE ACTIVATION; PHOSPHOLIPIDS; RECOMBINANT PROTEINS;

EID: 70350566092     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2009.08.051     Document Type: Article

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