Increasing DHA and EPA concentrations prolong action potential durations and reduce transient outward potassium currents in rat ventricular myocytes

Lipids

Volumn 46, Issue 2, 2011, Pages 163-170

  Li, Hong Xia ^a   Wang, Ru Xing ^b   Li, Xiao Rong ^b   Guo, Tao ^c   Wu, Ying ^b   Guo, Su Xia ^b   Sun, Li Ping ^b   Yang, Zhen Yu ^b   Yang, Xiang Jun ^a   Jiang, Wen Ping ^a  

^a THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

^c KUNMING MEDICAL UNIVERSITY   (China)

Author keywords

Action potential; Action potential duration; Docosahexaenoic acid; Eicosapentaenoic acid; n 3 Polyunsaturated fatty acid; Transient outward potassium current

Indexed keywords

DOCOSAHEXAENOIC ACID; ICOSAPENTAENOIC ACID;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; CELL ISOLATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; FEMALE; HEART MUSCLE CELL; HEART VENTRICLE; MALE; NONHUMAN; PATCH CLAMP; PHARMACOLOGICAL BLOCKING; POTASSIUM CURRENT; RAT;

ACTION POTENTIALS; ANIMALS; ANTI-ARRHYTHMIA AGENTS; DOCOSAHEXAENOIC ACIDS; DOSE-RESPONSE RELATIONSHIP, DRUG; EICOSAPENTAENOIC ACID; HEART VENTRICLES; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; POTASSIUM; RATS; RATS, SPRAGUE-DAWLEY; VENTRICULAR FUNCTION;

RATTUS;

EID: 79952317091     PISSN: 00244201     EISSN: 15589307     Source Type: Journal    
DOI: 10.1007/s11745-010-3503-3     Document Type: Article

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