General maternal medication use, folic acid, the MDR1 C3435T polymorphism, and the risk of a child with a congenital heart defect

American Journal of Obstetrics and Gynecology

Volumn 204, Issue 3, 2011, Pages 236.e1-236.e8

  Obermann Borst, Sylvia A ^a   Isaacs, Aaron ^a   Younes, Zobia ^a   Van Schaik, Ron H N ^a   Van Der Heiden, Ilse P ^a   Van Duyn, Cornelia M ^a   Steegers, Eric A P ^a   Steegers Theunissen, Régine P M ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

congenital heart malformation; drug; folic acid; gene environment; periconception; polymorphism

Indexed keywords

AGENTS ACTING ON THE GENITAL SYSTEM; ANALGESIC AGENT; ANTACID AGENT; ANTIBIOTIC AGENT; ANTICONVULSIVE AGENT; ANTIFUNGAL AGENT; ANTIHISTAMINIC AGENT; ANTIHYPERTENSIVE AGENT; ANTIINFECTIVE AGENT; ANTITHROMBOCYTIC AGENT; ANTITUSSIVE AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CYTOSINE; FOLIC ACID; HEMATOLOGIC AGENT; HOMEOPATHIC AGENT; HORMONE INHIBITOR; INSULIN; LAXATIVE; NEUROLEPTIC AGENT; PROLACTIN INHIBITOR; PROSTAGLANDIN SYNTHASE INHIBITOR; RESPIRATORY TRACT AGENT; SEX HORMONE; SPASMOLYTIC AGENT; THYMINE; THYROMIMETIC AGENT; UNCLASSIFIED DRUG;

ADULT; CHILD; CONCEPTION; CONFERENCE PAPER; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; DNA POLYMORPHISM; DRUG USE; FATHER; FEMALE; GENE; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; HETEROZYGOTE; HIGH RISK POPULATION; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; MDR1 GENE; MOTHER; PERINATAL DRUG EXPOSURE; POPULATION BASED CASE CONTROL STUDY; PRIORITY JOURNAL; RISK ASSESSMENT;

EID: 79952316924     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajog.2010.10.911     Document Type: Conference Paper

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