Inhibition of p53 induces invasion of serous borderline ovarian tumor cells by accentuating PI3K/Akt-mediated suppression of E-cadherin

Oncogene

Volumn 30, Issue 9, 2011, Pages 1020-1031

  Cheng, J C ^a   Auersperg, N ^a   Leung, P C K ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

E cadherin; invasion; ovarian cancer; p53; serous borderline ovarian tumors

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; BETA ACTIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P53; RETINOBLASTOMA PROTEIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR TWIST; UVOMORULIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CANCER GROWTH; CANCER INHIBITION; CANCER INVASION; CELL IMMORTALIZATION; CELL INVASION; CELL STRAIN; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; NONHUMAN; OVARY CARCINOMA; PRIORITY JOURNAL; PROTEIN INDUCTION; SEROUS BORDERLINE OVARIAN TUMOR; TRANSCRIPTION REGULATION; TUMOR CELL LINE;

ANTIGENS, VIRAL, TUMOR; BLOTTING, WESTERN; CADHERINS; CELL SURVIVAL; CYSTADENOCARCINOMA, SEROUS; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENE KNOCKDOWN TECHNIQUES; HUMANS; IN SITU HYBRIDIZATION; NEOPLASM INVASIVENESS; NEOPLASMS, GLANDULAR AND EPITHELIAL; OVARIAN NEOPLASMS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RETINOBLASTOMA PROTEIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SIMIAN VIRUS 40; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

SIMIAN VIRUS 40;

EID: 79952281861     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2010.486     Document Type: Article

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