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Volumn 25, Issue 4, 2011, Pages 1161-1167

Accumulation of lactosylceramide and overexpression of a PSC833-resistant P-glycoprotein in multidrug-resistant human sarcoma cells

Author keywords

Lactosylceramide; Multidrug resistance; P glycoprotein; Resistance to PSC833

Indexed keywords

CYCLOSPORIN A; DAUNORUBICIN; DOXORUBICIN; GLYCOPROTEIN P; LACTOSYLCERAMIDE; MULTIDRUG RESISTANCE PROTEIN 1; SPHINGOLIPID; VALSPODAR; VINBLASTINE;

EID: 79952223525     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2011.1180     Document Type: Article
Times cited : (10)

References (32)
  • 1
    • 31844444140 scopus 로고    scopus 로고
    • The molecular basis of multidrug resistance in cancer: The early years of P-glycoprotein research
    • DOI 10.1016/j.febslet.2005.12.060, PII S0014579305015437, ABC Transporters
    • Gottesman MM and Ling V: The molecular basis of multidrug resistance in cancer: the early years of P-glycoprotein research. FEBS Lett 580: 998-1009, 2006. (Pubitemid 43185280)
    • (2006) FEBS Letters , vol.580 , Issue.4 , pp. 998-1009
    • Gottesman, M.M.1    Ling, V.2
  • 2
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • Gottesman MM and Pastan I: Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem 62: 385-427, 1993. (Pubitemid 23237876)
    • (1993) Annual Review of Biochemistry , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 3
    • 0026048306 scopus 로고
    • Decreased DNA topoisomerase II in daunorubicin-resistant Ehrlich ascites tumor cells
    • Friche E, Danks MK, Schmidt CA and Beck WT: Decreased DNA topoisomerase II in daunorubicin-resistant Ehrlich ascites tumor cells. Cancer Res 51: 4213-4218, 1991.
    • (1991) Cancer Res , vol.51 , pp. 4213-4218
    • Friche, E.1    Danks, M.K.2    Schmidt, C.A.3    Beck, W.T.4
  • 7
    • 0030841332 scopus 로고    scopus 로고
    • Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines
    • Kool M, de Haas M, Scheffer GL, Scheper RJ, van Eijk MJ, Juijn JA, Baas F and Borst P: Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. Cancer Res 57: 3537-3547, 1997. (Pubitemid 27355505)
    • (1997) Cancer Research , vol.57 , Issue.16 , pp. 3537-3547
    • Kool, M.1    De, H.M.2    Scheffer, G.L.3    Scheper, R.J.4    Van, E.M.J.T.5    Juijn, J.A.6    Baas, F.7    Borst, P.8
  • 9
    • 33646568511 scopus 로고    scopus 로고
    • Mechanisms and strategies to overcome multiple drug resistance in cancer
    • Ozben T: Mechanisms and strategies to overcome multiple drug resistance in cancer. FEBS Lett 580: 2903-2909, 2006.
    • (2006) FEBS Lett , vol.580 , pp. 2903-2909
    • Ozben, T.1
  • 11
    • 0035888295 scopus 로고    scopus 로고
    • Elevation of glucosylceramide in multidrug-resistant cancer cells and accumulation in cytoplasmic droplets
    • DOI 10.1002/ijc.1449
    • Morjani H, Aouali N, Belhoussine R, Veldman RJ, Levade T and Manfait M: Elevation of glucosylceramide in multidrug-resistant cancer cells and accumulation in cytoplasmic droplets. Int J Cancer 94: 157-165, 2001. (Pubitemid 32911407)
    • (2001) International Journal of Cancer , vol.94 , Issue.2 , pp. 157-165
    • Morjani, H.1    Aouali, N.2    Belhoussine, R.3    Veldman, R.J.4    Levade, T.5    Manfait, M.6
  • 13
    • 0031019309 scopus 로고    scopus 로고
    • Agents that reverse multidrug resistance, tamoxifen, verapamil, and cyclosporin A, block glycosphingolipid metabolism by inhibiting ceramide glycosylation in human cancer cells
    • DOI 10.1074/jbc.272.3.1682
    • Lavie Y, Cao H, Volner A, Lucci A, Han TY, Geffen V, Giuliano AE and Cabot MC: Agents that reverse multidrug resistance, tamoxifen, verapamil, and cyclosporin A, block glycosphingolipid metabolism by inhibiting ceramide glycosylation in human cancer cells. J Biol Chem 272: 1682-1687, 1997. (Pubitemid 27043253)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.3 , pp. 1682-1687
    • Lavie, Y.1    Cao, H.-T.2    Volner, A.3    Lucci, A.4    Han, T.-Y.5    Geffen, V.6    Giuliano, A.E.7    Cabot, M.C.8
  • 14
    • 0000255378 scopus 로고    scopus 로고
    • Expression of glucosylceramide synthase, converting ceramide to glucosylceramide, confers adriamycin resistance in human breast cancer cells
    • Liu YY, Han TY, Giuliano AE and Cabot MC: Expression of glucosylceramide synthase, converting ceramide to glucosylceramide, confers adriamycin resistance in human breast cancer cells. J Biol Chem 274: 1140-1146, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 1140-1146
    • Liu, Y.Y.1    Han, T.Y.2    Giuliano, A.E.3    Cabot, M.C.4
  • 15
    • 0036632690 scopus 로고    scopus 로고
    • Altered sphingolipid metabolism in multidrug-resistant ovarian cancer cells is due to uncoupling of glycolipid biosynthesis in the Golgi apparatus
    • Veldman RJ, Klappe K, Hinrichs J, Hummel I, van der Schaaf G, Sietsma H and Kok JW: Altered sphingolipid metabolism in multidrug-resistant ovarian cancer cells is due to uncoupling of glycolipid biosynthesis in the Golgi apparatus. FASEB J 16: 1111-1113, 2002.
    • (2002) FASEB J , vol.16 , pp. 1111-1113
    • Veldman, R.J.1    Klappe, K.2    Hinrichs, J.3    Hummel, I.4    Van Der Schaaf, G.5    Sietsma, H.6    Kok, J.W.7
  • 17
    • 18144371163 scopus 로고    scopus 로고
    • Glucosylceramide synthase blockade down-regulates P-glycoprotein and resensitizes multidrug-resistant breast cancer cells to anticancer drugs
    • DOI 10.1158/0008-5472.CAN-04-2329
    • Gouaze V, Liu YY, Prickett CS, Yu JY, Giuliano AE and Cabot MC: Glucosylceramide synthase blockade down-regulates P-glycoprotein and resensitizes multidrug-resistant breast cancer cells to anticancer drugs. Cancer Res 65: 3861-3867, 2005. (Pubitemid 40616367)
    • (2005) Cancer Research , vol.65 , Issue.9 , pp. 3861-3867
    • Gouaze, V.1    Liu, Y.-Y.2    Prickett, C.S.3    Yu, J.Y.4    Giuliano, A.E.5    Cabot, M.C.6
  • 18
    • 0022352607 scopus 로고
    • Multidrug (pleiotropic) resistance in doxorubicin-selected variants of the human sarcoma cell line MES-SA
    • Harker WG and Sikic BI: Multidrug (pleiotropic) resistance in doxorubicin-selected variants of the human sarcoma cell line MES-SA. Cancer Res 45: 4091-4096, 1985. (Pubitemid 16224856)
    • (1985) Cancer Research , vol.45 , Issue.9 , pp. 4091-4096
    • Harker, W.G.1    Sikic, B.I.2
  • 19
    • 0037397619 scopus 로고    scopus 로고
    • Optimization of quantitative real-time RT-PCR parameters for the study of lymphoid malignancies
    • DOI 10.1038/sj.leu.2402880
    • Lossos IS, Czerwinski DK, Wechser MA and Levy R: Optimization of quantitative real-time RT-PCR parameters for the study of lymphoid malignancies. Leukemia 17: 789-795, 2003. (Pubitemid 36519378)
    • (2003) Leukemia , vol.17 , Issue.4 , pp. 789-795
    • Lossos, I.S.1    Czerwinski, D.K.2    Wechser, M.A.3    Levy, R.4
  • 20
    • 0036278859 scopus 로고    scopus 로고
    • Gene quantification using real-time quantitative PCR: An emerging technology hits the mainstream
    • Ginzinger DG: Gene quantification using real-time quantitative PCR: an emerging technology hits the mainstream. Exp Hematol 30: 503-512, 2002.
    • (2002) Exp Hematol , vol.30 , pp. 503-512
    • Ginzinger, D.G.1
  • 22
  • 23
    • 0028841512 scopus 로고
    • Decreased mutation rate for cellular resistance to doxorubicin and suppression of mdr1 gene activation by the cyclosporin PSC 833
    • Beketic-Oreskovic L, Duran GE, Chen G, Dumontet C and Sikic BI: Decreased mutation rate for cellular resistance to doxorubicin and suppression of mdr1 gene activation by the cyclosporin PSC 833. J Natl Cancer Inst 87: 1593-1602, 1995.
    • (1995) J Natl Cancer Inst , vol.87 , pp. 1593-1602
    • Beketic-Oreskovic, L.1    Duran, G.E.2    Chen, G.3    Dumontet, C.4    Sikic, B.I.5
  • 26
    • 0031041385 scopus 로고    scopus 로고
    • Multidrug-resistant human sarcoma cells with a mutant P-glycoprotein, altered phenotype, and resistance to cyclosporins
    • DOI 10.1074/jbc.272.9.5974
    • Chen G, Duran GE, Steger KA, Lacayo NJ, Jaffrezou JP, Dumontet C and Sikic BI: Multidrug-resistant human sarcoma cells with a mutant P-glycoprotein, altered phenotype, and resistance to cyclosporins. J Biol Chem 272: 5974-5982, 1997. (Pubitemid 27102435)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.9 , pp. 5974-5982
    • Chen, G.1    Duran, G.E.2    Steger, K.A.3    Lacayo, N.J.4    Jaffrezou, J.-P.5    Dumontet, C.6    Sikic, B.I.7
  • 27
    • 0036073348 scopus 로고    scopus 로고
    • Influence of ceramide metabolism on P-glycoprotein function in immature acute myeloid leukemia KG1a cells
    • DOI 10.1124/mol.62.2.304
    • Plo I, Lehne G, Beckstrom KJ, Maestre N, Bettaieb A, Laurent G and Lautier D: Influence of ceramide metabolism on P-glycoprotein function in immature acute myeloid leukemia KG1a cells. Mol Pharmacol 62: 304-312, 2002. (Pubitemid 34804110)
    • (2002) Molecular Pharmacology , vol.62 , Issue.2 , pp. 304-312
    • Plo, I.1    Lehne, G.2    Beckstrom, K.J.3    Maestre, N.4    Bettaieb, A.5    Laurent, G.6    Lautier, D.7
  • 30
    • 1242294365 scopus 로고    scopus 로고
    • ATP-binding Cassette Transporters Are Enriched in Non-caveolar Detergent-insoluble Glycosphingolipid-enriched Membrane Domains (DIGs) in Human Multidrug-resistant Cancer Cells
    • DOI 10.1074/jbc.M306857200
    • Hinrichs JW, Klappe K, Hummel I and Kok JW: ATP-binding cassette transporters are enriched in non-caveolar detergent-insoluble glycosphingolipid-enriched membrane domains (DIGs) in human multidrug-resistant cancer cells. J Biol Chem 279: 5734-5738, 2004. (Pubitemid 38220603)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.7 , pp. 5734-5738
    • Hinrichs, J.W.J.1    Klappe, K.2    Hummel, I.3    Kok, J.W.4
  • 31
    • 2442675466 scopus 로고    scopus 로고
    • MRP1 and glucosylceramide are coordinately over expressed and enriched in rafts during multidrug resistance acquisition in colon cancer cells
    • DOI 10.1002/ijc.20140
    • Klappe K, Hinrichs JW, Kroesen BJ, Sietsma H and Kok JW: MRP1 and glucosylceramide are coordinately over expressed and enriched in rafts during multidrug resistance acquisition in colon cancer cells. Int J Cancer 110: 511-522, 2004. (Pubitemid 38658016)
    • (2004) International Journal of Cancer , vol.110 , Issue.4 , pp. 511-522
    • Klappe, K.1    Hinrichs, J.W.J.2    Kroesen, B.-J.3    Sietsma, H.4    Kok, J.W.5
  • 32
    • 0035882104 scopus 로고    scopus 로고
    • Differential effects of glycosphingolipids on the detergent-insolubility of the glycosylphosphatidylinositol-anchored membrane dipeptidase
    • DOI 10.1042/0264-6021:3580209
    • Parkin ET, Turner AJ and Hooper NM: Differential effects of glycosphingolipids on the detergent-insolubility of the glycosylphosphatidylinositol-anchored membrane dipeptidase. Biochem J 358: 209-216, 2001. (Pubitemid 32778115)
    • (2001) Biochemical Journal , vol.358 , Issue.1 , pp. 209-216
    • Parkin, E.T.1    Turner, A.J.2    Hooper, N.M.3


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