Disseminated peritoneal leiomyomatosis after laparoscopic supracervical hysterectomy with characteristic molecular cytogenetic findings of uterine leiomyoma

Genes Chromosomes and Cancer

Volumn 49, Issue 12, 2010, Pages 1152-1160

  Ordulu, Zehra ^a   Dal Cin, Paola ^a   Chong, Wilson W S ^b   Choy, Kwong Wai ^b   Lee, Charles ^a   Muto, Michael G ^a   Quade, Bradley J ^a   Morton, Cynthia C ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CASE REPORT; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CHROMOSOME DELETION; COMPARATIVE GENOMIC HYBRIDIZATION; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENETICS; HUMAN; HYSTERECTOMY; LAPAROSCOPY; LEIOMYOMA; LEIOMYOMATOSIS; MIDDLE AGED; PATHOLOGY; PERITONEAL CAVITY; PERITONEUM TUMOR; UTERUS CANCER;

CHROMOSOME ABERRATIONS; CHROMOSOME DELETION; COMPARATIVE GENOMIC HYBRIDIZATION; CYTOGENETIC ANALYSIS; FEMALE; HUMANS; HYSTERECTOMY; IN SITU HYBRIDIZATION, FLUORESCENCE; LAPAROSCOPY; LEIOMYOMA; LEIOMYOMATOSIS; MIDDLE AGED; PERITONEAL CAVITY; PERITONEAL NEOPLASMS; UTERINE NEOPLASMS;

EID: 79952202077     PISSN: 10452257     EISSN: 10982264     Source Type: Journal    
DOI: 10.1002/gcc.20824     Document Type: Article

References (70)

1. Abramson S, Gilkeson RC, Goldstein JD, Woodard PK, Eisenberg R, Abramson N. 2001. Benign metastasizing leiomyoma: clinical, imaging, and pathologic correlation. AJR Am J Roentgenol 176:1409-1413.
2. Akkersdijk GJ, Flu PK, Giard RW, van Lent M, Wallenburg HC. 1990. Malignant leiomyomatosis peritonealis disseminata. Am J Obstet Gynecol 163:591-593.
3. Al-Talib A, Tulandi T. 2010. Pathophysiology and possible iatrogenic cause of leiomyomatosis peritonealis disseminata. Gynecol Obstet Invest 69:239-244.
4. Alam NA, Rowan AJ, Wortham NC, Pollard PJ, Mitchell M, Tyrer JP, Barclay E, Calonje E, Manek S, Adams SJ, Bowers PW, Burrows NP, Charles-Holmes R, Cook LJ, Daly BM, Ford GP, Fuller LC, Hadfield-Jones SE, Hardwick N, Highet AS, Keefe M, MacDonald-Hull SP, Potts ED, Crone M, Wilkinson S, Camacho-Martinez F, Jablonska S, Ratnavel R, MacDonald A, Mann RJ, Grice K, Guillet G, Lewis-Jones MS, McGrath H, Seukeran DC, Morrison PJ, Fleming S, Rahman S, Kelsell D, Leigh I, Olpin S, Tomlinson IP. 2003. Genetic and functional analyses of FH mutations in multiple cutaneous and uterine leiomyomatosis, hereditary leiomyomatosis and renal cancer, and fumarate hydratase deficiency. Hum Mol Genet 12:1241- 1252.
5. Aruh L, Taskin O, Demir N. 1993. Recurrent leiomyomatosis peritonealis disseminata. Int J Gynaecol Obstet 43:330-331.
6. Aterman K, Fraser GM, Lea RH. 1977. Disseminated peritoneal leiomyomatosis. Virchows Arch A Pathol Anat Histol 374:13-26.
7. Bekkers RL, Willemsen WN, Schijf CP, Massuger LF, Bulten J, Merkus JM. 1999. Leiomyomatosis peritonealis disseminata: does malignant transformation occur? A literature review. Gynecol Oncol 75:158-163.
8. Bell SW, Kempson RL, Hendrickson MR. 1994. Problematic uterine smooth muscle neoplasms. A clinicopathologic study of 213 cases. Am J Surg Pathol 18:535-558.
9. Buttram VC, Jr., Reiter RC. 1981. Uterine leiomyomata: etiology, symptomatology, and management. Fertil Steril 36:433-445.
10. Cramer SF, Patel A. 1990. The frequency of uterine leiomyomas. Am J Clin Pathol 94:435-438.
11. Dal Cin P, Moerman P, Deprest J, Brosens I, Van den Berghe H. 1995. A new cytogenetic subgroup in uterine leiomyoma is characterized by a deletion of the long arm of chromosome 3. Genes Chromosomes Cancer 13:219-220.
12. Dal Cin P, Quade BJ, Neskey DM, Kleinman MS, Weremowicz S, Morton CC. 2003. Intravenous leiomyomatosis is characterized by a der(14)t(12;14)(q15;q24). Genes Chromosomes Cancer 36:205-206.
13. Donnez O, Squifflet J, Leconte I, Jadoul P, Donnez J. 2007. Posthysterectomy pelvic adenomyotic masses observed in 8 cases out of a series of 1405 laparoscopic subtotal hysterectomies. J Minim Invasive Gynecol 14:156-160.
14. Drake A, Dhundee J, Buckley CH, Woolas R. 2001. Disseminated leiomyomatosis peritonealis in association with oestrogen secreting ovarian fibrothecoma. BJOG 108:661-664.
15. Einstein MH, Barakat RR, Chi DS, Sonoda Y, Alektiar KM, Hensley ML, Abu-Rustum NR. 2008. Management of uterine malignancy found incidentally after supracervical hysterectomy or uterine morcellation for presumed benign disease. Int J Gynecol Cancer 18:1065-1070.
16. Fletcher JA, Morton CC, Pavelka K, Lage JM. 1990. Chromosome aberrations in uterine smooth muscle tumors: potential diagnostic relevance of cytogenetic instability. Cancer Res 50:4092-4097.
17. Flynn M, Jamison M, Datta S, Myers E. 2006. Health care resource use for uterine fibroid tumors in the United States. Am J Obstet Gynecol 195:955-964.
18. Fusco A, Fedele M. 2007. Roles of HMGA proteins in cancer. Nat Rev Cancer 7:899-910.
19. Gattas GJ, Quade BJ, Nowak RA, Morton CC. 1999. HMGIC expression in human adult and fetal tissues and in uterine leiomyomata. Genes Chromosomes Cancer 25:316-322.
20. Gross KL, Morton CC. 2001. Genetics and the development of fibroids. Clin Obstet Gynecol 44:335-349.
21. Gross KL, Neskey DM, Manchanda N, Weremowicz S, Kleinman MS, Nowak RA, Ligon AH, Rogalla P, Drechsler K, Bullerdiek J, Morton CC. 2003. HMGA2 expression in uterine leiomyomata and myometrium: quantitative analysis and tissue culture studies. Genes Chromosomes Cancer 38:68-79.
22. Gross KL, Panhuysen CI, Kleinman MS, Goldhammer H, Jones ES, Nassery N, Stewart EA, Morton CC. 2004. Involvement of fumarate hydratase in nonsyndromic uterine leiomyomas: genetic linkage analysis and FISH studies. Genes Chromosomes Cancer 41:183-190.
23. Halama N, Grauling-Halama SA, Daboul I. 2005. Familial clustering of Leiomyomatosis peritonealis disseminata: an unknown genetic syndrome? BMC Gastroenterol 5:33.
24. Hales HA, Peterson CM, Jones KP, Quinn JD. 1992. Leiomyomatosis peritonealis disseminata treated with a gonadotropinreleasing hormone agonist. A case report. Am J Obstet Gynecol 167:515-516.
25. Hardman WJ, III, Majmudar B. 1996. Leiomyomatosis peritonealis disseminata: clinicopathologic analysis of five cases. South Med J 89:291-294.
26. Hartmann KE, Birnbaum H, Ben-Hamadi R, Wu EQ, Farrell MH, Spalding J, Stang P. 2006. Annual costs associated with diagnosis of uterine leiomyomata. Obstet Gynecol 108:930-937.
27. Hodge JC, T. Cuenco K, Huyck KL, Somasundaram P, Panhuysen CI, Stewart EA, Morton CC. 2009a. Uterine leiomyomata and decreased height: a common HMGA2 predisposition allele. Hum Genet 125:257-263.
28. Hodge JC, Park PJ, Dreyfuss JM, Assil-Kishawi I, Somasundaram P, Semere LG, Quade BJ, Lynch AM, Stewart EA, Morton CC. 2009b. Identifying the molecular signature of the interstitial deletion 7q subgroup of uterine leiomyomata using a paired analysis. Genes Chromosomes Cancer 48:865-885.
29. Kiuru M, Lehtonen R, Arola J, Salovaara R, Jarvinen H, Aittomaki K, Sjoberg J, Visakorpi T, Knuutila S, Isola J, Delahunt B, Herva R, Launonen V, Karhu A, Aaltonen LA. 2002. Few FH mutations in sporadic counterparts of tumor types observed in hereditary leiomyomatosis and renal cell cancer families. Cancer Res 62:4554-4557.
30. Koninckx PR, Donders G, Vandecruys H. 2000. Umbilical endometriosis after unprotected removal of uterine pieces through the umbilicus. J Am Assoc Gynecol Laparosc 7:227-232.
31. Kuchinka BD, Kalousek DK, Lomax BL, Harrison KJ, Barrett IJ. 1995. Interphase cytogenetic analysis of single cell suspensions prepared from previously formalin-fixed and paraffin-embedded tissues. Mod Pathol 8:183-186.
32. Kumar S, Sharma JB, Verma D, Gupta P, Roy KK, Malhotra N. 2008. Disseminated peritoneal leiomyomatosis: an unusual complication of laparoscopic myomectomy. Arch Gynecol Obstet 278:93-95.
33. Lausen I, Jensen OJ, Andersen E, Lindahl F. 1990. Disseminated peritoneal leiomyomatosis with malignant change, in a male. Virchows Arch A Pathol Anat Histopathol 417:173-175.
34. Lehtonen R, Kiuru M, Vanharanta S, Sjoberg J, Aaltonen LM, Aittomaki K, Arola J, Butzow R, Eng C, Husgafvel-Pursiainen K, Isola J, Jarvinen H, Koivisto P, Mecklin JP, Peltomaki P, Salovaara R, Wasenius VM, Karhu A, Launonen V, Nupponen NN, Aaltonen LA. 2004. Biallelic inactivation of fumarate hydratase (FH) occurs in nonsyndromic uterine leiomyomas but is rare in other tumors. Am J Pathol 164:17-22.
35. Lepine LA, Hillis SD, Marchbanks PA, Koonin LM, Morrow B, Kieke BA, Wilcox LS. 1997. Hysterectomy surveillance-United States, 1980-1993. MMWR CDC Surveill Summ 46:1-15.
36. Mark J, Havel G, Dahlenfors R, Wedell B. 1991. Cytogenetics of multiple uterine leiomyomas, parametrial leiomyoma and disseminated peritoneal leiomyomatosis. Anticancer Res 11:33-39.
37. Mashal RD, Fejzo ML, Friedman AJ, Mitchner N, Nowak RA, Rein MS, Morton CC, Sklar J. 1994. Analysis of androgen receptor DNA reveals the independent clonal origins of uterine leiomyomata and the secondary nature of cytogenetic aberrations in the development of leiomyomata. Genes Chromosomes Cancer 11:1-6.
38. Meloni AM, Surti U, Contento AM, Davare J, Sandberg AA. 1992. Uterine leiomyomas: cytogenetic and histologic profile. Obstet Gynecol 80:209-217.
39. Miyake T, Enomoto T, Ueda Y, Ikuma K, Morii E, Matsuzaki S, Murata Y. 2009. A case of disseminated peritoneal leiomyomatosis developing after laparoscope-assisted myomectomy. Gynecol Obstet Invest 67:96-102.
40. Mulvany NJ, Slavin JL, Ostor AG, Fortune DW. 1994. Intravenous leiomyomatosis of the uterus: a clinicopathologic study of 22 cases. Int J Gynecol Pathol 13:1-9.
41. Nakayama Y, Kitamura S, Kawachi K, Kawata T, Fukutomi M, Hasegawa J, Morita R. 1994. Intravenous leiomyomatosis extending into the right atrium. Cardiovasc Surg 2:642-645.
42. Nilbert M, Heim S. 1990. Uterine leiomyoma cytogenetics. Genes Chromosomes Cancer 2:3-13.
43. Nilbert M, Strombeck B. 1992. Independent origin of uterine leiomyomas with karyotypically identical alterations. Gynecol Obstet Invest 33:246-248.
44. Nilbert M, Heim S, Mandahl N, Floderus UM, Willen H, Mitelman F. 1990. Characteristic chromosome abnormalities, including rearrangements of 6p, del(7q), {thorn}12, and t(12;14), in 44 uterine leiomyomas. Hum Genet 85:605-611.
45. Ostrzenski A. 1997. Uterine leiomyoma particle growing in an abdominal-wall incision after laparoscopic retrieval. Obstet Gynecol 89:853-854.
46. Paul PG, Koshy AK. 2006. Multiple peritoneal parasitic myomas after laparoscopic myomectomy and morcellation. Fertil Steril 85:492-493.
47. Peters WA III, Howard DR, Andersen WA, Figge DC. 1994. Uterine smooth-muscle tumors of uncertain malignant potential. Obstet Gynecol 83:1015-1020.
48. Quade BJ, McLachlin CM, Soto-Wright V, Zuckerman J, Mutter GL, Morton CC. 1997. Disseminated peritoneal leiomyomatosis. Clonality analysis by X chromosome inactivation and cytogenetics of a clinically benign smooth muscle proliferation. Am J Pathol 150:2153-2166.
49. Quade BJ, Weremowicz S, Neskey DM, Vanni R, Ladd C, Dal Cin P, Morton CC. 2003. Fusion transcripts involving HMGA2 are not a common molecular mechanism in uterine leiomyomata with rearrangements in 12q15. Cancer Res 63:1351-1358.
50. Rajab KE, Aradi AN, Datta BN. 2000. Postmenopausal leimyomatosis peritonealis disseminata. Int J Gynaecol Obstet 68:271- 272.
51. Redon R, Ishikawa S, Fitch KR, Feuk L, Perry GH, Andrews TD, Fiegler H, Shapero MH, Carson AR, Chen W, Cho EK, Dallaire S, Freeman JL, Gonzalez JR, Gratacos M, Huang J, Kalaitzopoulos D, Komura D, MacDonald JR, Marshall CR, Mei R, Montgomery L, Nishimura K, Okamura K, Shen F, Somerville MJ, Tchinda J, Valsesia A, Woodwark C, Yang F, Zhang J, Zerjal T, Zhang J, Armengol L, Conrad DF, Estivill X, Tyler-Smith C, Carter NP, Aburatani H, Lee C, Jones KW, Scherer SW, Hurles ME. 2006. Global variation in copy number in the human genome. Nature 444:444-454.
52. Rein MS, Friedman AJ, Barbieri RL, Pavelka K, Fletcher JA, Morton CC. 1991. Cytogenetic abnormalities in uterine leiomyomata. Obstet Gynecol 77:923-926.
53. Rein MS, Powell WL, Walters FC, Weremowicz S, Cantor RM, Barbieri RL, Morton CC. 1998. Cytogenetic abnormalities in uterine myomas are associated with myoma size. Mol Hum Reprod 4:83-86.
54. Schneider A. 1997. Recurrence of unclassifiable uterine cancer after modified laparoscopic hysterectomy with morcellation. Am J Obstet Gynecol 177:478-479.
55. Schoenberg Fejzo M, Ashar HR, Krauter KS, Powell WL, Rein MS, Weremowicz S, Yoon SJ, Kucherlapati RS, Chada K, Morton CC. 1996. Translocation breakpoints upstream of the HMGIC gene in uterine leiomyomata suggest dysregulation of this gene by a mechanism different from that in lipomas. Genes Chromosomes Cancer 17:1-6.
56. Schwartz SM, Marshall LM, Baird DD. 2000. Epidemiologic contributions to understanding the etiology of uterine leiomyomata. Environ Health Perspect 108(Suppl 5):821-827.
57. Sebat J, Lakshmi B, Troge J, Alexander J, Young J, Lundin P, Maner S, Massa H, Walker M, Chi M, Navin N, Lucito R, Healy J, Hicks J, Ye K, Reiner A, Gilliam TC, Trask B, Patterson N, Zetterberg A, Wigler M. 2004. Large-scale copy number polymorphism in the human genome. Science 305:525-528.
58. Sepilian V, Della Badia C. 2003. Iatrogenic endometriosis caused by uterine morcellation during a supracervical hysterectomy. Obstet Gynecol 102:1125-1127.
59. Sharma P, Chaturvedi KU, Gupta R, Nigam S. 2004. Leiomyomatosis peritonealis disseminata with malignant change in a postmenopausal woman. Gynecol Oncol 95:742-745.
60. Sreekantaiah C, Davis JR, Sandberg AA. 1993. Chromosomal abnormalities in leiomyosarcomas. Am J Pathol 142:293-305.
61. Sutherland JA, Wilson EA, Edger DE, Powell D. 1980. Ultrastructure and steroid-binding studies in leiomyomatosis peritonealis disseminata. Am J Obstet Gynecol 136:992-996.
62. Takeda A, Mori M, Sakai K, Mitsui T, Nakamura H. 2007. Parasitic peritoneal leiomyomatosis diagnosed 6 years after laparoscopic myomectomy with electric tissue morcellation: report of a case and review of the literature. J Minim Invasive Gynecol 14:770-775.
63. Tallini G, Dal Cin P. 1999. HMGI(Y) and HMGI-C dysregulation: a common occurrence in human tumors. Adv Anat Pathol 6:237-246.
64. Thian YL, Tan KH, Kwek JW, Wang J, Chern B, Yam KL. 2009. Leiomyomatosis peritonealis disseminata and subcutaneous myoma-a rare complication of laparoscopic myomectomy. Abdom Imaging 34:235-238.
65. Tomlinson IP, Alam NA, Rowan AJ, Barclay E, Jaeger EE, Kelsell D, Leigh I, Gorman P, Lamlum H, Rahman S, Roylance RR, Olpin S, Bevan S, Barker K, Hearle N, Houlston RS, Kiuru M, Lehtonen R, Karhu A, Vilkki S, Laiho P, Eklund C, Vierimaa O, Aittomaki K, Hietala M, Sistonen P, Paetau A, Salovaara R, Herva R, Launonen V, Aaltonen LA. 2002. Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer. Nat Genet 30:406- 410.
66. Turc-Carel C, Dal Cin P, Boghosian L, Terk-Zakarian J, Sandberg AA. 1988. Consistent breakpoints in region 14q22-q24 in uterine leiomyoma. Cancer Genet Cytogenet 32:25-31.
67. Vikhlyaeva EM, Khodzhaeva ZS, Fantschenko ND. 1995. Familial predisposition to uterine leiomyomas. Int J Gynaecol Obstet 51:127-131.
68. Weremowicz S, Schofield DE. 2007. Preparation of cells from formalin-fixed, paraffin-embedded tissue for use in fluorescence in situ hybridization (FISH) experiments. Curr Protoc Hum Genet. Chapter 8: Unit 8.8.
69. Wise LA, Palmer JR, Harlow BL, Spiegelman D, Stewart EA, Adams-Campbell LL, Rosenberg L. 2004. Reproductive factors, hormonal contraception, and risk of uterine leiomyomata in African-American women: a prospective study. Am J Epidemiol 159:113-123.
70. Yamaguchi T, Imamura Y, Yamamoto T, Fukuda M. 2003. Leiomyomatosis peritonealis disseminata with malignant change in a man. Pathol Int 53:179-185.