Deletion of vitamin D receptor leads to premature emphysema/COPD by increased matrix metalloproteinases and lymphoid aggregates formation

Biochemical and Biophysical Research Communications

Volumn 406, Issue 1, 2011, Pages 127-133

  Sundar, Isaac K ^a   Hwang, Jae Woong ^a   Wu, Shaoping ^a   Sun, Jun ^a   Rahman, Irfan ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

COPD; Inflammation; Lung; Metalloproteinases; Vitamin D; Vitamin D receptor

Indexed keywords

GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MACROPHAGE ELASTASE; VITAMIN D RECEPTOR;

ACETYLATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL AGGREGATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DISEASE ASSOCIATION; EMPHYSEMA; ENZYME INDUCTION; FEMALE; GENE DELETION; GENE SILENCING; IMMUNE DYSREGULATION; INFLAMMATION; LUNG FUNCTION; LYMPHOID CELL; MALE; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; WILD TYPE;

ANIMALS; EMPHYSEMA; EXTRACELLULAR MATRIX PROTEINS; GENE DELETION; LYMPHOCYTES; MATRIX METALLOPROTEINASES; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; NF-KAPPA B; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RECEPTORS, CALCITRIOL;

MUS;

EID: 79952193836     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.02.011     Document Type: Article

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