A sesquiterpenol extract potently suppresses inflammation in macrophages and mice skin and prevents chronic liver damage in mice through JNK-dependent HO-1 expression

Phytochemistry

Volumn 72, Issue 4-5, 2011, Pages 391-399

  Shyur, Lie Fen ^a   Huang, Chi Chang ^a   Hsu, Yu Ying ^a,b   Cheng, Ya Wen ^a   Yang, Shiaw Der ^b  

^a AGRICULTURAL BIOTECHNOLOGY RESEARCH CENTER   (Taiwan)

^b NATIONAL TSING HUA UNIVERSITY   (Taiwan)

Author keywords

Cryptomeria japonica; Hepatoprotection; HO 1; Proinflammatory mediators; Sesquiterpenol; Taxodiaceae

Indexed keywords

2,7(14),10 BISABOLATRIEN 1 OL 4 ONE; 2,7(14),10-BISABOLATRIEN-1-OL-4-ONE; CARBON TETRACHLORIDE; CYCLOOXYGENASE 2 INHIBITOR; HEME OXYGENASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; PHORBOL 13 ACETATE 12 MYRISTATE; PROSTAGLANDIN E2; SESQUITERPENE; SILYMARIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ARTICLE; CHEMISTRY; DERMATITIS; DRUG ANTAGONISM; DRUG EFFECT; HUMAN; INFLAMMATION; ISOLATION AND PURIFICATION; JAPANESE CEDAR; LIVER DISEASE; MACROPHAGE; METABOLISM; MOUSE; SECRETION; SKIN;

ANIMALS; CARBON TETRACHLORIDE; CRYPTOMERIA; CYCLOOXYGENASE 2 INHIBITORS; DERMATITIS; DINOPROSTONE; HEME OXYGENASE-1; HUMANS; INFLAMMATION; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; LIVER DISEASES; MACROPHAGES; MICE; NITRIC OXIDE SYNTHASE TYPE II; RNA, MESSENGER; SESQUITERPENES; SILYMARIN; SKIN; TETRADECANOYLPHORBOL ACETATE; TUMOR NECROSIS FACTOR-ALPHA;

CRYPTOMERIA JAPONICA; CUPRESSACEAE; MUS;

EID: 79952193517     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phytochem.2010.12.019     Document Type: Article

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