β4-Subunit increases Slo responsiveness to physiological Ca2+ concentrations and together with β1 reduces surface expression of Slo in hair cells

American Journal of Physiology - Cell Physiology

Volumn 300, Issue 3, 2011, Pages

  Bai, Jun Ping ^a   Surguchev, Alexei ^a   Navaratnam, Dhasakumar ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Beta sub units; Electrical tuning; Large conductance potassium channels; Relaxation times

Indexed keywords

AMINO ACID; CALCIUM ION; COMPLEMENTARY DNA; DNA; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; POTASSIUM CHANNEL; RNA 18S; SMALL INTERFERING RNA; YELLOW FLUORESCENT PROTEIN;

ANIMAL CELL; ARTICLE; CHICKEN; CONTROLLED STUDY; FLUORESCENCE ACTIVATED CELL SORTING; HAIR CELL; HUMAN; HUMAN CELL; MEMBRANE CONDUCTANCE; NONHUMAN; OOCYTE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RNA INTERFERENCE; VOLTAGE CLAMP;

ANIMALS; CALCIUM; CALCIUM SIGNALING; CELL MEMBRANE; CHICKENS; COCHLEA; DOWN-REGULATION; HAIR CELLS, AUDITORY; ION CHANNEL GATING; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNEL BETA SUBUNITS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MECHANOTRANSDUCTION, CELLULAR; MEMBRANE POTENTIALS; OOCYTES; XENOPUS LAEVIS;

VERTEBRATA;

EID: 79952138384     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00449.2010     Document Type: Article

References (49)

1. + channels in vascular smooth muscle during hypertension. J Clin Invest 112: 717-724, 2003.
2. Art JJ, Crawford AC, Fettiplace R. Electrical resonance and membrane currents in turtle cochlear hair cells. Hear Res 22: 31-36, 1986. (Pubitemid 16068828)
3. Art JJ, Fettiplace R. Variation of membrane properties in hair cells isolated from the turtle cochlea. J Physiol 385: 207-242, 1987. (Pubitemid 17048934)
4. Atkinson NS, Robertson GA, Ganetzky B. A component of calcium-activated potassium channels encoded by the Drosophila slo locus. Science 253: 551-555, 1991.
5. 2+ buffers. Methods Cell Biol 40: 3-29, 1994.
6. Butler A, Tsunoda S, McCobb DP, Wei A, Salkoff L. mSlo, a complex mouse gene encoding "maxi" calcium-activated potassium channels. Science 261: 221-224, 1993.
7. Colquhoun D, Sigworth FJ. Fitting and statistical analysis of single-channel records. In Single-Channel Recording, edited by Sakmann B, Neher E. New York: Plenum, 1995, p. 483-588.
8. Crawford AC, Fettiplace R. An electrical tuning mechanism in turtle cochlear hair cells. J Physiol 312: 377-412, 1981. (Pubitemid 11123006)
9. Diez-Sampedro A, Silverman WR, Bautista JF, Richerson GB. Mechanism of increased open probability by a mutation of the BK channel. J Neurophysiol 96: 1507-1516, 2006. (Pubitemid 44371539)
10. Du W, Bautista JF, Yang H, Diez-Sampedro A, You SA, Wang L, Kotagal P, Luders HO, Shi J, Cui J, Richerson GB, Wang QK. Calcium-sensitive potassium channelopathy in human epilepsy and paroxysmal movement disorder. Nat Genet 37: 733-738, 2005. (Pubitemid 41754890)
11. Duncan RK, Fuchs PA. Variation in large-conductance, calcium-activated potassium channels from hair cells along the chicken basilar papilla. J Physiol 547: 357-371, 2003. (Pubitemid 36304970)
12. Fernandez-Fernandez JM, Tomas M, Vazquez E, Orio P, Latorre R, Senti M, Marrugat J, Valverde MA. Gain-of-function mutation in the KCNMB1 potassium channel subunit is associated with low prevalence of diastolic hypertension. J Clin Invest 113: 1032-1039, 2004. (Pubitemid 38544125)
13. Fettiplace R, Fuchs PA. Mechanisms of hair cell tuning. Annu Rev Physiol 61: 809-834, 1999. (Pubitemid 29143193)
14. Frucht CS, Uduman M, Duke JL, Kleinstein SH, Santos-Sacchi J, Navaratnam DS. Gene expression analysis of forskolin treated basilar papillae identifies microRNA181a as a mediator of proliferation. PLoS One 5: e11502, 2010.
15. Fuchs PA, Nagai T, Evans MG. Electrical tuning in hair cells isolated from the chick cochlea. J Neurosci 8: 2460-2467, 1988.
16. Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch 391: 85-100, 1981. (Pubitemid 11012976)
17. Horrigan FT, Aldrich RW. Allosteric voltage gating of potassium channels. II. Mslo channel gating charge movement in the absence of Ca2+. J Gen Physiol 114: 305-336, 1999. (Pubitemid 29380156)
18. 2+ binding and channel opening in large conductance (BK) potassium channels. J Gen Physiol 120: 267-305, 2002.
19. Horrigan FT, Cui J, Aldrich RW. Allosteric voltage gating of potassium channels. I. Mslo ionic currents in the absence of Ca2+. J Gen Physiol 114: 277-304, 1999. (Pubitemid 29380155)
20. Housley GD, Marcotti W, Navaratnam D, Yamoah EN. Hair cells - beyond the transducer. J Membr Biol 209: 89-118, 2006. (Pubitemid 43886875)
21. Hudspeth AJ, Lewis RS. A model for electrical resonance and frequency tuning in saccular hair cells of the bull-frog, Rana catesbeiana. J Physiol 400: 275-297, 1988.
22. + channels at fluorescently labeled presynaptic active zones of hair cells. Proc Natl Acad Sci USA 91: 7578-7582, 1994.
23. + channels in auditory hair cells. Ann NY Acad Sci 868: 379-385, 1999.
24. + channel spliced variants in the tonotopic organization of the turtle cochlea. J Physiol 518: 653-665, 1999.
25. + channel splice variants and their distribution in the turtle cochlea. Proc Biol Sci 265: 685-692, 1998.
26. Lewis RS, Hudspeth AJ. Voltage- and ion-dependent conductances in solitary vertebrate hair cells. Nature 304: 538-541, 1983. (Pubitemid 13026951)
27. MacKinnon R. Potassium channels. FEBS Lett 555: 62-65, 2003. (Pubitemid 37431098)
28. Magleby KL. Gating mechanism of BK (Slo1) channels: so near, yet so far. J Gen Physiol 121: 81-96, 2003. (Pubitemid 36255339)
29. Magleby KL, Pallotta BS. Calcium dependence of open and shut interval distributions from calcium-activated potassium channels in cultured rat muscle. J Physiol 344: 585-604, 1983. (Pubitemid 14233229)
30. Mathur R, Zheng J, Yan Y, Sigworth FJ. Role of the S3-S4 linker in Shaker potassium channel activation. J Gen Physiol 109: 191-199, 1997. (Pubitemid 27078406)
31. McManus OB, Magleby KL. Kinetic states and modes of single large-conductance calcium-activated potassium channels in cultured rat skeletal muscle. J Physiol 402: 79-120, 1988.
32. Miranda-Rottmann S, Kozlov AS, Hudspeth AJ. Highly specific alternative splicing of transcripts encoding BK channels in the chicken's cochlea is a minor determinant of the tonotopic gradient. Mol Cell Biol 30: 3646-3660, 2010.
33. Navaratnam D, Bai JP, Samaranayake H, Santos-Sacchi J. N-terminal-mediated homomultimerization of prestin, the outer hair cell motor protein. Biophys J 89: 3345-3352, 2005. (Pubitemid 41636090)
34. + channel splice variants among hair cells along the tonotopic axis of the chick cochlea. Neuron 19: 1077-1085, 1997.
35. + channel protects against hypertension. J Clin Invest 113: 955-957, 2004.
36. 2+-independent mechanism. J Gen Physiol 115: 719-736, 2000.
37. 2+-activated potassium channels by retaining the gating in the bursting states. J Gen Physiol 113: 425-440, 1999.
38. Ohmori H. Studies of ionic currents in the isolated vestibular hair cell of the chick. J Physiol 350: 561-581, 1984. (Pubitemid 14062656)
39. + (BK) channel. J Gen Physiol 127: 191-204, 2006.
40. Ramanathan K, Michael TH, Fuchs PA. Beta subunits modulate alternatively spliced, large conductance, calcium-activated potassium channels of avian hair cells. J Neurosci 20: 1675-1684, 2000. (Pubitemid 30220365)
41. Ramanathan K, Michael TH, Jiang GJ, Hiel H, Fuchs PA. A molecular mechanism for electrical tuning of cochlear hair cells. Science 283: 215-217, 1999.
42. Roberts WM, Jacobs RA, Hudspeth AJ. Colocalization of ion channels involved in frequency selectivity and synaptic transmission at presynaptic active zones of hair cells. J Neurosci 10: 3664-3684, 1990.
43. + channel isoforms along the tonotopic gradient of the chicken's cochlea. Neuron 19: 1061-1075, 1997.
44. 2+-activated potassium (BK) alpha-subunit but not the BK beta1-subunit leads to progressive hearing loss. Proc Natl Acad Sci USA 101: 12922-12927, 2004.
45. + (BK) channels in chick hair cells are clustered and colocalized with apical-basal and tonotopic gradients. J Physiol 560: 13-20, 2004.
46. Sigworth FJ, Sine SM. Data transformations for improved display and fitting of single-channel dwell time histograms. Biophys J 52: 1047-1054, 1987.
47. Tucker T, Fettiplace R. Confocal imaging of calcium microdomains and calcium extrusion in turtle hair cells. Neuron 15: 1323-1335, 1995. (Pubitemid 26005370)
48. Wu YC, Art JJ, Goodman MB, Fettiplace R. A kinetic description of the calcium-activated potassium channel and its application to electrical tuning of hair cells. Prog Biophys Mol Biol 63: 131-158, 1995.
49. Wu YC, Tucker T, Fettiplace R. A theoretical study of calcium microdomains in turtle hair cells. Biophys J 71: 2256-2275, 1996. (Pubitemid 26367694)