Human pluripotent stem cells differentiated in fully defined medium generate hematopoietic CD34+ and CD34- progenitors with distinct characteristics

PLoS ONE

Volumn 6, Issue 2, 2011, Pages

  Chicha, Laurie ^a   Feki, Anis ^b   Boni, Alessandro ^a   Irion, Olivier ^b   Hovatta, Outi ^b,c   Jaconi, Marisa ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^c KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBIN; BONE MORPHOGENETIC PROTEIN 4; FLT3 LIGAND; MESSENGER RNA; OCTAMER TRANSCRIPTION FACTOR 4; STEM CELL FACTOR; THROMBOPOIETIN; TRANSCRIPTION FACTOR RUNX1; TRANSCRIPTION FACTOR TAL1; VASCULOTROPIN; CD34 ANTIGEN;

ARTICLE; CD34 SELECTION; CELL DIFFERENTIATION; CELL MATURATION; CELL STRUCTURE; COLONY FORMING UNIT; CONTROLLED STUDY; CULTURE MEDIUM; DOWN REGULATION; EMBRYO; ERYTHROCYTE; ERYTHROID CELL; FLUORESCENCE ACTIVATED CELL SORTING; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; LEUKOCYTE; LIQUID CULTURE; PHENOTYPE; PLURIPOTENT STEM CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION; UMBILICAL CORD BLOOD; ANIMAL; BONE MARROW CELL; CELL CULTURE; CELL LINEAGE; CELL SIZE; CHEMISTRY; CULTURE TECHNIQUE; CYTOLOGY; DRUG EFFECT; EMBRYONIC STEM CELL; METABOLISM; PHYSIOLOGY;

ANIMALIA;

ANIMALS; ANTIGENS, CD34; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL LINEAGE; CELL SIZE; CELLS, CULTURED; CULTURE MEDIA; CULTURE MEDIA, SERUM-FREE; EMBRYONIC STEM CELLS; HEMATOPOIETIC STEM CELLS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MYELOID CELLS; PLURIPOTENT STEM CELLS;

EID: 79952137714     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0014733     Document Type: Article

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