Epigenetic regulation of genes in learning and memory

Essays in Biochemistry

Volumn 48, Issue , 2010, Pages 263-274

  Roth, Tania L ^a,b   Roth, Eric D ^a,b   Sweatt, J David ^a  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF DELAWARE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA METHYLATION; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; HUMAN; LEARNING; MEMORY; REVIEW;

DNA METHYLATION; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION; HUMANS; LEARNING; MEMORY;

EID: 79952112954     PISSN: 00711365     EISSN: None     Source Type: Journal    
DOI: 10.1042/BSE0480263     Document Type: Article

References (39)

1. Borrelli, E., Nestler, E.J., Allis, C.D. and Sassone-Corsi, P. (2008) Decoding the epigenetic language of neuronal plasticity. Neuron 60, 961-974
2. Gräff, J. and Mansuy, I.M. (2008) Epigenetic codes in cognition and behaviour. Behav. Brain Res. 192, 70-87
3. Roth, T.L. and Sweatt, J.D. (2009) Regulation of chromatin structure in memory formation. Curr. Opin. Neurobiol. 19, 336-342
4. Miranda, T.B. and Jones, P.A. (2007) DNA methylation: the nuts and bolts of repression. J. Cell. Physiol. 213, 384-390
5. Chahrour, M., Jung, S.Y., Shaw, C., Zhou, X., Wong, S.T.C., Qin, J. and Zoghbi, H.Y. (2008) MeCP2, a key contributor to neurological disease, activates and represses transcription. Science 320, 1224-1229
6. Yasui, D.H., Peddada, S., Bieda, M.C., Vallero, R.O., Hogart, A., Nagarajan, R.P., Thatcher, K.N., Farnham, P.J. and Lasalle, J.M. (2007) Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genes. Proc. Natl. Acad. Sci. U.S.A. 104, 19416-19421
7. Bhattacharya, S.K., Ramchandani, S., Cervoni, N. and Szyf, M. (1999) A mammalian protein with specific demethylase activity for mCpG DNA. Nature 397, 579-583
8. Barreto, G., Schafer, A., Marhold, J., Stach, D., Swaminathan, S.K., Handa, V., Doderlein, G., Maltry, N., Wu, W., Lyko, F. and Niehrs, C. (2007) Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation. Nature 445, 671-675
9. Ma, D.K., Jang, M.-H., Guo, J.U., Kitabatake, Y., Chang, M.-l., Pow-anpongkul, N., Flavell, R.A., Lu, B., Ming, G.-l. and Song, H. (2009) Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis. Science 323, 1074-1077
10. Strahl, B.D. and Allis, C.D. (2000) The language of covalent histone modifications. Nature 403, 41-45
11. Weaver, I.C.G., Cervoni, N., Champagne, F.A., D'Alessio, A.C., Sharma, S., Seckl, J.R., Dymov, S., Szyf, M. and Meaney, M.J. (2004) Epigenetic programming by maternal behavior. Nat. Neurosci. 7, 847-854
12. Brown, S.E., Weaver, I.C.G., Meaney, M.J. and Szyf, M. (2008) Regional-specific global cytosine methylation and DNA methyltransferase expression in the adult rat hippocampus. Neurosci. Lett. 440, 49-53
13. Feng, J., Chang, H., Li, E. and Fan, G. (2005) Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system. J. Neurosci. Res. 79, 734-746
14. Goto, K., Numata, M., Komura, J., Ono, T., Bestor, T.H. and Kondo, H. (1994) Expression of DNA methyltransferase gene in mature and immature neurons as well as proliferating cells in mice. Differentiation 56, 39-44
15. Levenson, J.M., Roth, T.L., Lubin, F.D., Miller, C.A., Huang, I.C., Desai, P., Malone, L.M. and Sweatt, J.D. (2006) Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus. J. Biol. Chem. 281, 15763-15773
16. Miller, C.A., Campbell, S.L. and Sweatt, J.D. (2008) DNA methylation and histone acetylation work in concert to regulate memory formation and synaptic plasticity. Neurobiol. Learn. Mem. 89, 599-603
17. Golshani, P., Hutnick, L., Schweizer, F. and Fan, G. (2005) Conditional Dnmt1 deletion in dorsal forebrain disrupts development of somatosensory barrel cortex and thalamocortical long-term potentiation. Thalamus Relat. Syst. 3, 227-233
18. Nelson, E.D., Kavalali, E.T. and Monteggia, L.M. (2008) Activity-dependent suppression of miniature neurotransmission through the regulation of DNA methylation. J. Neurosci. 28, 395-406
19. Feng, J., Yu, Z., Campbell, S.L., Le, T., Li, E., Sweatt, J.D., Silva, A.J. and Fan, G. (2010) Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nat. Neurosci. 13, 423-430
20. Alarcon, J.M., Malleret, G., Touzani, K., Vronskaya, S., Ishii, S., Kandel, E.R. and Barco, A. (2004) Chromatin acetylation, memory, and LTP are impaired in CBP+/- mice: a model for the cognitive deficit in Rubinstein-Taybi syndrome and its amelioration. Neuron 42, 947-959
21. Wood, M.A., Kaplan, M.P., Park, A., Blanchard, E.J., Oliviera, A.M., Lombardi, T.L. and Abel, T. (2005) Transgenic mice expressing a truncated form of CREB-binding protein (CBP) exhibit deficits in hippocampal synaptic plasticity and memory storage. Learn. Mem. 12, 111-119
22. Levenson, J.M., O'Riordan, K.J., Brown, K.D., Trinh, M.A., Molfese, D.L. and Sweatt, J.D. (2004) Regulation of histone acetylation during memory formation in the hippocampus. J. Biol. Chem. 279, 40545-40559
23. Miller, C.A. and Sweatt, J.D. (2007) Covalent modification of DNA regulates memory formation. Neuron 53, 857-869
24. Lubin, F.D., Roth, T.L. and Sweatt, J.D. (2008) Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory. J. Neurosci. 28, 10576-10586
25. Adachi, M., Autry, A.E., Covington, III, H.E. and Monteggia, L.M. (2009) MeCP2-mediated transcription repression in the basolateral amygdala may underlie heightened anxiety in a mouse model of Rett syndrome. J. Neurosci. 29, 4218-4227
26. Roth, T.L., Lubin, F.D., Funk, A.J. and Sweatt, J.D. (2009) Lasting epigenetic influence of early-life adversity on the BDNF gene. Biol. Psychiatry 65, 760-769
27. Murgatroyd, C., Patchev, A.V., Wu, Y., Micale, V., Bockmühl, Y., Fischer, D., Holsboer, F., Wotjak, C.T., Almeida, O.F. and Spengler, D. (2009) Dynamic DNA methylation programs persistent adverse effects of early-life stress. Nat. Neurosci. 12, 1559-1566
28. Korzus, E., Rosenfeld, M.G. and Mayford, M. (2004) CBP histone acetyltransferase activity is a critical component on memory consolidation Neuron 42, 961-972
29. Chwang, W.B., O'Riordan, K.J., Levenson, J.M. and Sweatt, J.D. (2006) ERK/MAPK regulates hippocampal histone phosphorylation following contextual fear conditioning. Learn. Mem. 13, 322-328
30. Fischer, A., Sananbenesi, F., Wang, X., Dobbin, M. and Tsai, L.-H. (2007) Recovery of learning and memory is associated with chromatin remodeling. Nature 447, 178-182
31. Malvaez, M., Sanchis-Segura, C., Vo, D., Lattal, K.M. and Wood, M.A. (2009) Modulation of chromatin modification facilitates extinction of cocaine-induced conditioned place preference. Biol. Psychiatry 67, 36-43
32. Kilgore, M., Miller, C.A., Fass, D.M., Hennig, K.M., Haggarty, S.J., Sweatt, J.D. and Rumbaugh, G. (2010) Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in a mouse model of Alzheimer's disease. Neuropsychopharmacology 35, 870-880
33. Bredy, T.W. and Barad, M. (2008) The histone deacetylase inhibitor valproic acid enhances acquisition, extinction, and reconsolidation of conditioned fear. Learn. Mem. 15, 39-45
34. Koshibu, K., Gräff, J., Beullens, M., Heitz, F.D., Berchtold, D., Russig, H., Farinelli, M., Bollen, M. and Mansuy, I.M. (2009) Protein phosphatase 1 regulates the histone code for long-term memory. J. Neurosci. 29, 13079-13089
35. Tsankova, N., Berton, O., Renthal, W., Kumar, A., Neve, R. and Nestler, E. (2006) Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nat. Neurosci. 9, 519-525
36. Reul, J.M., Hesketh, S.A., Collins, A. and Mecinas, M.G. (2009) Epigenetic mechanisms in the dentate gyrus act as a molecular switch in hippocampus-associated memory formation. Epigenetics 4, 434-439
37. Hunter, R.G., McCarthy, K.J., Milne, T.A., Pfaff, D.W. and McEwen, B.S. (2009) Regulation of hippocampal H3 histone methylation by acute and chronic stress. Proc. Natl. Acad. Sci. U.S.A. 106, 20912-20917
38. Roth, T.L., Lubin, F.D., Sodhi, M. and Kleinman, J.E. (2009) Epigenetic mechanisms in schizophrenia. Biochim. Biophys. Acta 1790, 869-877
39. Gräff, J. and Mansuy, I.M. (2009) Epigenetic dysregulation in cognitive disorders. Eur. J. Neurosci. 30, 1-8