-
1
-
-
33745155105
-
Determination of confidence intervals of metabolic fluxes estimated from stable isotope measurements
-
Antoniewicz M.R., Kelleher J.K., Stephanopoulos G. Determination of confidence intervals of metabolic fluxes estimated from stable isotope measurements. Metabolic Engineering 2006, 8:324-337.
-
(2006)
Metabolic Engineering
, vol.8
, pp. 324-337
-
-
Antoniewicz, M.R.1
Kelleher, J.K.2
Stephanopoulos, G.3
-
2
-
-
35348941242
-
Accurate assessment of amino acid mass isotopomer distributions for metabolic flux analysis
-
Antoniewicz M.R., Kelleher J.K., Stephanopoulos G. Accurate assessment of amino acid mass isotopomer distributions for metabolic flux analysis. Analytical Chemistry 2007, 79:7554-7559.
-
(2007)
Analytical Chemistry
, vol.79
, pp. 7554-7559
-
-
Antoniewicz, M.R.1
Kelleher, J.K.2
Stephanopoulos, G.3
-
3
-
-
33845679072
-
Elementary metabolite units (EMU): A novel framework for modeling isotopic distributions
-
Antoniewicz M.R., Kelleher J.K., Stephanopoulos G. Elementary metabolite units (EMU): A novel framework for modeling isotopic distributions. Metabolic Engineering 2007, 9:68-86.
-
(2007)
Metabolic Engineering
, vol.9
, pp. 68-86
-
-
Antoniewicz, M.R.1
Kelleher, J.K.2
Stephanopoulos, G.3
-
4
-
-
34249297627
-
Metabolic flux analysis in a nonstationary system: fed-batch fermentation of a high yielding strain of E. coli producing 1,3-propanediol
-
Antoniewicz M.R., Kraynie D.F., Laffend L.A., Gonzalez-Lergier J., Kelleher J.K., Stephanopoulos G. Metabolic flux analysis in a nonstationary system: fed-batch fermentation of a high yielding strain of E. coli producing 1,3-propanediol. Metabolic Engineering 2007, 9:277-292.
-
(2007)
Metabolic Engineering
, vol.9
, pp. 277-292
-
-
Antoniewicz, M.R.1
Kraynie, D.F.2
Laffend, L.A.3
Gonzalez-Lergier, J.4
Kelleher, J.K.5
Stephanopoulos, G.6
-
5
-
-
76749097100
-
Metabolic flux analysis and pharmaceutical production
-
Boghigian B.A., Seth G., Kiss R., Pfeifer B.A. Metabolic flux analysis and pharmaceutical production. Metabolic Engineering 2010, 12(2):81-95.
-
(2010)
Metabolic Engineering
, vol.12
, Issue.2
, pp. 81-95
-
-
Boghigian, B.A.1
Seth, G.2
Kiss, R.3
Pfeifer, B.A.4
-
6
-
-
0038242823
-
Analysis of gluconeogenic pathways in vivo by distribution of H-2 in plasma glucose: comparison of nuclear magnetic resonance and mass spectrometry
-
Burgess S.C., Nuss M., Chandramouli V., Hardin D.S., Rice M., Landau B.R., Malloy C.R., Sherry A.D. Analysis of gluconeogenic pathways in vivo by distribution of H-2 in plasma glucose: comparison of nuclear magnetic resonance and mass spectrometry. Analytical Biochemistry 2003, 318:321-324.
-
(2003)
Analytical Biochemistry
, vol.318
, pp. 321-324
-
-
Burgess, S.C.1
Nuss, M.2
Chandramouli, V.3
Hardin, D.S.4
Rice, M.5
Landau, B.R.6
Malloy, C.R.7
Sherry, A.D.8
-
7
-
-
0037439386
-
Noninvasive evaluation of liver metabolism by H-2 and C-13 NMR isotopomer analysis of human urine
-
Burgess S.C., Weis B., Jones J.G., Smith E., Merritt M.E., Margolis D., Sherry A.D., Malloy C.R. Noninvasive evaluation of liver metabolism by H-2 and C-13 NMR isotopomer analysis of human urine. Analytical Biochemistry 2003, 312:228-234.
-
(2003)
Analytical Biochemistry
, vol.312
, pp. 228-234
-
-
Burgess, S.C.1
Weis, B.2
Jones, J.G.3
Smith, E.4
Merritt, M.E.5
Margolis, D.6
Sherry, A.D.7
Malloy, C.R.8
-
8
-
-
0032587953
-
Multiple bond C-13-C-13 spin-spin coupling provides complementary information in a C-13 NMR isotopomer analysis of glutamate
-
Carvalho R.A., Babcock E.E., Jeffrey F.M.H., Sherry A.D., Malloy C.R. Multiple bond C-13-C-13 spin-spin coupling provides complementary information in a C-13 NMR isotopomer analysis of glutamate. Magnetic Resonance in Medicine 1999, 42:197-200.
-
(1999)
Magnetic Resonance in Medicine
, vol.42
, pp. 197-200
-
-
Carvalho, R.A.1
Babcock, E.E.2
Jeffrey, F.M.H.3
Sherry, A.D.4
Malloy, C.R.5
-
9
-
-
79952145912
-
-
Resolving the TCA cycle and pentose-phosphate pathway of Clostridium acetobutylicum ATCC 824: Isotopomer analysis, in vitro activities and expression analysis. Biotechnology Journal 10.1002/biot.201000282
-
Crown, S.B., Indurthi, D.C., Ahn, W.S., Choi, J., Papoutsakis, E.T., Antoniewicz, M.R. 2010. Resolving the TCA cycle and pentose-phosphate pathway of Clostridium acetobutylicum ATCC 824: Isotopomer analysis, in vitro activities and expression analysis. Biotechnology Journal 10.1002/biot.201000282.
-
(2010)
-
-
Crown, S.B.1
Indurthi, D.C.2
Ahn, W.S.3
Choi, J.4
Papoutsakis, E.T.5
Antoniewicz, M.R.6
-
10
-
-
0034233268
-
GC-MS analysis of amino acids rapidly provides rich information for isotopomer balancing
-
Dauner M., Sauer U. GC-MS analysis of amino acids rapidly provides rich information for isotopomer balancing. Biotechnology Progress 2000, 16:642-649.
-
(2000)
Biotechnology Progress
, vol.16
, pp. 642-649
-
-
Dauner, M.1
Sauer, U.2
-
11
-
-
0742270738
-
A critical perspective of the use of C-13-isotopomer analysis by GCMS and NMR as applied to cardiac metabolism
-
Des Rosiers C., Lloyd S., Comte B., Chatham J.C. A critical perspective of the use of C-13-isotopomer analysis by GCMS and NMR as applied to cardiac metabolism. Metabolic Engineering 2004, 6:44-58.
-
(2004)
Metabolic Engineering
, vol.6
, pp. 44-58
-
-
Des Rosiers, C.1
Lloyd, S.2
Comte, B.3
Chatham, J.C.4
-
12
-
-
0037079597
-
C-13 isotopomer analysis of glutamate by tandem mass spectrometry
-
Jeffrey F.M.H., Roach J.S., Storey C.J., Sherry A.D., Malloy C.R. C-13 isotopomer analysis of glutamate by tandem mass spectrometry. Analytical Biochemistry. 2002, 300:192-205.
-
(2002)
Analytical Biochemistry.
, vol.300
, pp. 192-205
-
-
Jeffrey, F.M.H.1
Roach, J.S.2
Storey, C.J.3
Sherry, A.D.4
Malloy, C.R.5
-
13
-
-
1642503087
-
Glucose production, gluconeogenesis, and hepatic tricarboxylic acid cycle fluxes measured by nuclear magnetic resonance analysis of a single glucose derivative
-
Jin E.S., Jones J.G., Merritt M., Burgess S.C., Malloy C.R., Sherry A.D. Glucose production, gluconeogenesis, and hepatic tricarboxylic acid cycle fluxes measured by nuclear magnetic resonance analysis of a single glucose derivative. Analytical Biochemistry 2004, 327:149-155.
-
(2004)
Analytical Biochemistry
, vol.327
, pp. 149-155
-
-
Jin, E.S.1
Jones, J.G.2
Merritt, M.3
Burgess, S.C.4
Malloy, C.R.5
Sherry, A.D.6
-
14
-
-
0030754203
-
Measurement of gluconeogenesis and pyruvate recycling in the rat liver: a simple analysis of glucose and glutamate isotopomers during metabolism of [1,2,3-C-13(3)]propionate
-
Jones J.G., Naidoo R., Sherry A.D., Jeffrey F.M.H., Cottam G.L., Malloy C.R. Measurement of gluconeogenesis and pyruvate recycling in the rat liver: a simple analysis of glucose and glutamate isotopomers during metabolism of [1,2,3-C-13(3)]propionate. Febs Letters 1997, 412:131-137.
-
(1997)
Febs Letters
, vol.412
, pp. 131-137
-
-
Jones, J.G.1
Naidoo, R.2
Sherry, A.D.3
Jeffrey, F.M.H.4
Cottam, G.L.5
Malloy, C.R.6
-
15
-
-
0026522051
-
Model equations for condensation biosynthesis using stable isotopes and radioisotopes
-
Kelleher J.K., Masterson T.M. Model equations for condensation biosynthesis using stable isotopes and radioisotopes. American Journal of Physiology 1992, 262:E118-25.
-
(1992)
American Journal of Physiology
, vol.262
-
-
Kelleher, J.K.1
Masterson, T.M.2
-
16
-
-
0026794983
-
Isotopomer spectral analysis of triglyceride fatty acid synthesis in 3T3-L1 cells
-
Kharroubi A.T., Masterson T.M., Aldaghlas T.A., Kennedy K.A., Kelleher J.K. Isotopomer spectral analysis of triglyceride fatty acid synthesis in 3T3-L1 cells. American Journal of Physiology 1992, 263:E667-75.
-
(1992)
American Journal of Physiology
, vol.263
-
-
Kharroubi, A.T.1
Masterson, T.M.2
Aldaghlas, T.A.3
Kennedy, K.A.4
Kelleher, J.K.5
-
17
-
-
33845657876
-
Determination of carbon labeling distribution of intracellular metabolites from single fragment ions by ion chromatography tandem mass spectrometry
-
Kiefer P., Nicolas C., Letisse F., Portais J.C. Determination of carbon labeling distribution of intracellular metabolites from single fragment ions by ion chromatography tandem mass spectrometry. Analytical Biochemistry 2007, 360:182-188.
-
(2007)
Analytical Biochemistry
, vol.360
, pp. 182-188
-
-
Kiefer, P.1
Nicolas, C.2
Letisse, F.3
Portais, J.C.4
-
18
-
-
33846995458
-
Metabolic flux analysis of a glycerol-overproducing Saccharomyces cerevisiae strain based on GC-MS, LC-MS and NMR-derived C-13-labelling data
-
Kleijn R.J., Geertman J.M.A., Nfor B.K., Ras C., Schipper D., Pronk J.T., Heijnen J.J., van Maris A.J.A., van Winden W.A. Metabolic flux analysis of a glycerol-overproducing Saccharomyces cerevisiae strain based on GC-MS, LC-MS and NMR-derived C-13-labelling data. Fems Yeast Research 2007, 7:216-231.
-
(2007)
Fems Yeast Research
, vol.7
, pp. 216-231
-
-
Kleijn, R.J.1
Geertman, J.M.A.2
Nfor, B.K.3
Ras, C.4
Schipper, D.5
Pronk, J.T.6
Heijnen, J.J.7
van Maris, A.J.A.8
van Winden, W.A.9
-
19
-
-
33745758232
-
Application of Mass Spectrometry for Metabolite Identification
-
Ma S.K., Chowdhury S.B., Alton K. Application of Mass Spectrometry for Metabolite Identification. Current Drug Metabolism 2006, 7:503-523.
-
(2006)
Current Drug Metabolism
, vol.7
, pp. 503-523
-
-
Ma, S.K.1
Chowdhury, S.B.2
Alton, K.3
-
20
-
-
0025078865
-
Analysis of tricarboxylic acid cycle of the heart using 13C isotope isomers
-
Malloy C.R., Sherry A.D., Jeffrey F.M. Analysis of tricarboxylic acid cycle of the heart using 13C isotope isomers. American Journal of Physiology 1990, 259(3 Pt 2):H987-95.
-
(1990)
American Journal of Physiology
, vol.259
, Issue.3 PART 2
-
-
Malloy, C.R.1
Sherry, A.D.2
Jeffrey, F.M.3
-
21
-
-
0023126525
-
Carbon Flux through Citric-acid Cycle Pathways in Perfused Heart by C-13 NMR-Spectroscopy
-
Malloy C.R., Sherry A.D., Jeffrey F.M.H. Carbon Flux through Citric-acid Cycle Pathways in Perfused Heart by C-13 NMR-Spectroscopy. Febs Letters 1987, 212:58-62.
-
(1987)
Febs Letters
, vol.212
, pp. 58-62
-
-
Malloy, C.R.1
Sherry, A.D.2
Jeffrey, F.M.H.3
-
22
-
-
70449519259
-
Evaluation of 13C isotopic tracers for metabolic flux analysis in mammalian cells
-
Metallo C.M., Walther J.L., Stephanopoulos G. Evaluation of 13C isotopic tracers for metabolic flux analysis in mammalian cells. Journal of Biotechnology 2009, 144:167-174.
-
(2009)
Journal of Biotechnology
, vol.144
, pp. 167-174
-
-
Metallo, C.M.1
Walther, J.L.2
Stephanopoulos, G.3
-
23
-
-
66149122278
-
Linking high-resolution metabolic flux phenotypes and transcriptional regulation in yeast modulated by the global regulator Gcn4p
-
Moxley J.F., Jewett M.C., Antoniewicz M.R., Villas-Boas S.G., Alper H., Wheeler R.T., Tong L., Hinnebusch A.G., Ideker T., Nielsen J., Stephanopoulos G. Linking high-resolution metabolic flux phenotypes and transcriptional regulation in yeast modulated by the global regulator Gcn4p. Proceedings of the National Academy of Sciences 2009, 106:6477-6482.
-
(2009)
Proceedings of the National Academy of Sciences
, vol.106
, pp. 6477-6482
-
-
Moxley, J.F.1
Jewett, M.C.2
Antoniewicz, M.R.3
Villas-Boas, S.G.4
Alper, H.5
Wheeler, R.T.6
Tong, L.7
Hinnebusch, A.G.8
Ideker, T.9
Nielsen, J.10
Stephanopoulos, G.11
-
24
-
-
39049180766
-
Structural Determination of O-glycans by Tandem Mass Spectrometry
-
Robbe C., Michalski J.-C., Capon C. Structural Determination of O-glycans by Tandem Mass Spectrometry. Methods in Molecular Biology (Clifton, N.J.) 2006, 347:109-123.
-
(2006)
Methods in Molecular Biology (Clifton, N.J.)
, vol.347
, pp. 109-123
-
-
Robbe, C.1
Michalski, J.-C.2
Capon, C.3
-
25
-
-
33846061120
-
Metabolic networks in motion: C-13-based flux analysis
-
Sauer U. Metabolic networks in motion: C-13-based flux analysis. Molecular Systems Biology 2006, 2.
-
(2006)
Molecular Systems Biology
, pp. 2
-
-
Sauer, U.1
-
26
-
-
0343471424
-
Modeling isotopomer distributions in biochemical networks using isotopomer mapping matrices
-
Schmidt K., Carlsen M., Nielsen J., Villadsen J. Modeling isotopomer distributions in biochemical networks using isotopomer mapping matrices. Biotechnology and Bioengineering 1997, 55:831-840.
-
(1997)
Biotechnology and Bioengineering
, vol.55
, pp. 831-840
-
-
Schmidt, K.1
Carlsen, M.2
Nielsen, J.3
Villadsen, J.4
-
27
-
-
0013596620
-
Deuterium as an Indicator in the Study of Intermediary Metabolism
-
Schoenheimer R., Rittenberg D. Deuterium as an Indicator in the Study of Intermediary Metabolism. Science 1935, 82:156-157.
-
(1935)
Science
, vol.82
, pp. 156-157
-
-
Schoenheimer, R.1
Rittenberg, D.2
-
28
-
-
3643134833
-
The Application of Isotopes to the Study of Intermediary Metabolism
-
Schoenheimer R., Rittenberg D. The Application of Isotopes to the Study of Intermediary Metabolism. Science 1938, 87:221-226.
-
(1938)
Science
, vol.87
, pp. 221-226
-
-
Schoenheimer, R.1
Rittenberg, D.2
-
29
-
-
58149268329
-
Aldehyde-alcohol dehydrogenase and/or thiolase overexpression coupled with CoA transferase downregulation lead to higher alcohol titers and selectivity in Clostridium acetobutylicum fermentations
-
Sillers R., Al-Hinai M.A., Papoutsakis E.T. Aldehyde-alcohol dehydrogenase and/or thiolase overexpression coupled with CoA transferase downregulation lead to higher alcohol titers and selectivity in Clostridium acetobutylicum fermentations. Biotechnology and Bioengineering 2009, 102:38-49.
-
(2009)
Biotechnology and Bioengineering
, vol.102
, pp. 38-49
-
-
Sillers, R.1
Al-Hinai, M.A.2
Papoutsakis, E.T.3
-
30
-
-
76749140314
-
Improved computational performance of MFA using elementary metabolite units and flux coupling
-
Suthers P.F., Chang Y.J., Maranas C.D. Improved computational performance of MFA using elementary metabolite units and flux coupling. Metabolic Engineering 2010, 12(2):123-128.
-
(2010)
Metabolic Engineering
, vol.12
, Issue.2
, pp. 123-128
-
-
Suthers, P.F.1
Chang, Y.J.2
Maranas, C.D.3
-
31
-
-
0029146299
-
Biosynthetically Directed Fractional C-13-Labeling of Proteinogenic Amino-Acids-an Efficient Analytical Tool to Investigate Intermediary Metabolism
-
Szyperski T. Biosynthetically Directed Fractional C-13-Labeling of Proteinogenic Amino-Acids-an Efficient Analytical Tool to Investigate Intermediary Metabolism. European Journal of Biochemistry 1995, 232:433-448.
-
(1995)
European Journal of Biochemistry
, vol.232
, pp. 433-448
-
-
Szyperski, T.1
-
32
-
-
0035212187
-
Innovations in generation and analysis of 2D [C-13, H-1] COSYNMR spectra for metabolic flux analysis purposes
-
van Winden W., Schipper D., Verheijen P., Heijnen J. Innovations in generation and analysis of 2D [C-13, H-1] COSYNMR spectra for metabolic flux analysis purposes. Metabolic Engineering 2001, 3:322-343.
-
(2001)
Metabolic Engineering
, vol.3
, pp. 322-343
-
-
van Winden, W.1
Schipper, D.2
Verheijen, P.3
Heijnen, J.4
-
33
-
-
0021149774
-
Determination of Flux through The Branch Point of 2 Metabolic Cycles-The Trycarboxlic-Acid Cycle and The Glyoxylate Shunt
-
Walsh K., Koshland D.E. Determination of Flux through The Branch Point of 2 Metabolic Cycles-The Trycarboxlic-Acid Cycle and The Glyoxylate Shunt. Journal of Biological Chemistry 1984, 259:9646-9654.
-
(1984)
Journal of Biological Chemistry
, vol.259
, pp. 9646-9654
-
-
Walsh, K.1
Koshland, D.E.2
-
35
-
-
0343267841
-
Bidirectional reaction steps in metabolic networks: III. Explicit solution and analysis of isotopomer labeling systems
-
Wiechert W., Mollney M., Isermann N., Wurzel M., de Graaf A.A. Bidirectional reaction steps in metabolic networks: III. Explicit solution and analysis of isotopomer labeling systems. Biotechnol. Bioeng. 1999, 66:69-85.
-
(1999)
Biotechnol. Bioeng.
, vol.66
, pp. 69-85
-
-
Wiechert, W.1
Mollney, M.2
Isermann, N.3
Wurzel, M.4
de Graaf, A.A.5
-
36
-
-
78049451371
-
-
Metabolome, transcriptome and metabolic flux analysis of arabinose fermentation by engineered Saccharomyces cerevisiae. Metabolic Engineering 12
-
Wisselink, H.W., Cipollina, C., Oud, B., Crimi, B., Heijnen, J.J., Pronk, J.T., van Maris, A.J., 2010. Metabolome, transcriptome and metabolic flux analysis of arabinose fermentation by engineered Saccharomyces cerevisiae. Metabolic Engineering 12 (6), 537-551.
-
(2010)
, Issue.6
, pp. 537-551
-
-
Wisselink, H.W.1
Cipollina, C.2
Oud, B.3
Crimi, B.4
Heijnen, J.J.5
Pronk, J.T.6
van Maris, A.J.7
-
39
-
-
51049091904
-
Quantifying reductive carboxylation flux of glutamine to lipid in a brown adipocyte cell line
-
Yoo H., Antoniewicz M.R., Stephanopoulos G., Kelleher J.K. Quantifying reductive carboxylation flux of glutamine to lipid in a brown adipocyte cell line. Journal of Biological Chemistry 2008, 283:20621-20627.
-
(2008)
Journal of Biological Chemistry
, vol.283
, pp. 20621-20627
-
-
Yoo, H.1
Antoniewicz, M.R.2
Stephanopoulos, G.3
Kelleher, J.K.4
-
40
-
-
38449111120
-
An elementary metabolite unit (EMU) based method of isotopically nonstationary flux analysis
-
Young J.D., Walther J.L., Antoniewicz M.R., Yoo H., Stephanopoulos G. An elementary metabolite unit (EMU) based method of isotopically nonstationary flux analysis. Biotechnology and Bioengineering 2008, 99:686-699.
-
(2008)
Biotechnology and Bioengineering
, vol.99
, pp. 686-699
-
-
Young, J.D.1
Walther, J.L.2
Antoniewicz, M.R.3
Yoo, H.4
Stephanopoulos, G.5
|