Phosphodiesterase 4 inhibitors enhance sexual pleasure-seeking activity in rodents

Pharmacology Biochemistry and Behavior

Volumn 98, Issue 3, 2011, Pages 349-355

  Yuan, Peixiong ^a   Tragon, Tyson ^a   Xia, Menghang ^b   Leclair, Christopher A ^b   Skoumbourdis, Amanda P ^b   Zheng, Wei ^b   Thomas, Craig J ^b   Huang, Ruili ^b   Austin, Christopher P ^b   Chen, Guang ^a,c   Guitart, Xavier ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^c JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Depression; PDE4; Pleasure seeking activity; Postmortem human brain

Indexed keywords

CITALOPRAM; NCGC 00167114; NCGC 00168459; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE IV B; PHOSPHODIESTERASE IV D; PHOSPHODIESTERASE IV INHIBITOR; SEROTONIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; CINGULATE GYRUS; CONTROLLED STUDY; FEMALE; HUMAN; LEARNED HELPLESSNESS; MAJOR DEPRESSION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEROTONIN RELEASE; SEXUAL BEHAVIOR;

ANIMALS; BLOTTING, WESTERN; FEMALE; MALE; MICE; PHOSPHODIESTERASE 4 INHIBITORS; SEXUAL BEHAVIOR, ANIMAL;

ANIMALIA; MUS; RODENTIA;

EID: 79952104312     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pbb.2011.02.001     Document Type: Article

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