Phosphatidylinositol 3,4,5-triphosphate-dependent rac exchanger 1 (P-Rex-1), a guanine nucleotide exchange factor for rac, mediates angiogenic responses to stromal cell-derived factor-1/chemokine stromal cell derived factor-1 (SDF-1/CXCL-12) linked to rac activation, endothelial cell migration, and in vitro angiogenesis

Molecular Pharmacology

Volumn 77, Issue 3, 2010, Pages 435-442

  Carretero Ortega, Jorge ^a   Walsh, Colin T ^b   Hernández García, Ricardo ^a   Reyes Cruz, Guadalupe ^a   Brown, Joan Heller ^b   Vázquez Prado, José ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

^b San Diego   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P REX 1; RAC PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; STROMAL CELL DERIVED FACTOR 1; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION;

BASE SEQUENCE; CELL LINE; CELL MOVEMENT; CELLS, CULTURED; CHEMOKINE CXCL12; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; GENE KNOCKDOWN TECHNIQUES; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; MOLECULAR SEQUENCE DATA; NEOVASCULARIZATION, PHYSIOLOGIC; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 77149152165     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.109.060400     Document Type: Article

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